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    Results: 1 to 50 of 365

    1.

    Autophagy inhibition in combination cancer treatment.

    Livesey KM, Tang D, Zeh HJ, Lotze MT.

    Curr Opin Investig Drugs. 2009 Dec;10(12):1269-79.PMID: 19943199 [PubMed - in process]

    2.

    The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival.

    Kang R, Tang D, Schapiro NE, Livesey KM, Farkas A, Loughran P, Bierhaus A, Lotze MT, Zeh HJ.

    Cell Death Differ. 2009 Oct 16. [Epub ahead of print]PMID: 19834494 [PubMed - as supplied by publisher]Related articles

    3.

    Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cells.

    Lotfi R, Herzog GI, DeMarco RA, Beer-Stolz D, Lee JJ, Rubartelli A, Schrezenmeier H, Lotze MT.

    J Immunol. 2009 Oct 15;183(8):5023-31. Epub 2009 Sep 30.PMID: 19794066 [PubMed - indexed for MEDLINE]Related articles

    4.

    Receptor-mediated signalling in plants: molecular patterns and programmes.

    Tör M, Lotze MT, Holton N.

    J Exp Bot. 2009;60(13):3645-54. Epub 2009 Jul 23. Review.PMID: 19628572 [PubMed - in process]Related articles

    5.

    Ethyl pyruvate administration inhibits hepatic tumor growth.

    Liang X, Chavez AR, Schapiro NE, Loughran P, Thorne SH, Amoscato AA, Zeh HJ, Beer-Stolz D, Lotze MT, de Vera ME.

    J Leukoc Biol. 2009 Sep;86(3):599-607.PMID: 19584311 [PubMed - indexed for MEDLINE]Related articles

    6.

    Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology.

    Tahara H, Sato M, Thurin M, Wang E, Butterfield LH, Disis ML, Fox BA, Lee PP, Khleif SN, Wigginton JM, Ambs S, Akutsu Y, Chaussabel D, Doki Y, Eremin O, Fridman WH, Hirohashi Y, Imai K, Jacobson J, Jinushi M, Kanamoto A, Kashani-Sabet M, Kato K, Kawakami Y, Kirkwood JM, Kleen TO, Lehmann PV, Liotta L, Lotze MT, Maio M, Malyguine A, Masucci G, Matsubara H, Mayrand-Chung S, Nakamura K, Nishikawa H, Palucka AK, Petricoin EF, Pos Z, Ribas A, Rivoltini L, Sato N, Shiku H, Slingluff CL, Streicher H, Stroncek DF, Takeuchi H, Toyota M, Wada H, Wu X, Wulfkuhle J, Yaguchi T, Zeskind B, Zhao Y, Zocca MB, Marincola FM.

    J Transl Med. 2009 Jun 17;7:45.PMID: 19534815 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.

    Ueda R, Kohanbash G, Sasaki K, Fujita M, Zhu X, Kastenhuber ER, McDonald HA, Potter DM, Hamilton RL, Lotze MT, Khan SA, Sobol RW, Okada H.

    Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10746-51. Epub 2009 Jun 11.PMID: 19520829 [PubMed - indexed for MEDLINE]Related articles

    8.

    Low-dose cisplatin administration in murine cecal ligation and puncture prevents the systemic release of HMGB1 and attenuates lethality.

    Pan P, Cardinal J, Dhupar R, Rosengart MR, Lotze MT, Geller DA, Billiar TR, Tsung A.

    J Leukoc Biol. 2009 Sep;86(3):625-32.PMID: 19487305 [PubMed - indexed for MEDLINE]Related articles

    9.

    Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.

    Davé SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE.

    J Leukoc Biol. 2009 Sep;86(3):633-43. Epub 2009 May 19.PMID: 19454652 [PubMed - indexed for MEDLINE]Related articles

    10.

    Molecular basis of metastasis.

    Lee JJ, Lotze MT.

    N Engl J Med. 2009 Apr 16;360(16):1679; author reply 1679-80. No abstract available. PMID: 19373967 [PubMed - indexed for MEDLINE]Related articles

    11.

    RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation.

    Sparvero LJ, Asafu-Adjei D, Kang R, Tang D, Amin N, Im J, Rutledge R, Lin B, Amoscato AA, Zeh HJ, Lotze MT.

    J Transl Med. 2009 Mar 17;7:17. Review.PMID: 19292913 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Immunotherapy for cancer: promoting innate immunity.

    Lotfi R, Schrezenmeier H, Lotze MT.

    Front Biosci. 2009 Jan 1;14:818-32.PMID: 19273102 [PubMed - indexed for MEDLINE]Related articles

    13.

    Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function.

    Tang D, Kang R, Xiao W, Zhang H, Lotze MT, Wang H, Xiao X.

    Am J Respir Cell Mol Biol. 2009 Dec;41(6):651-60. Epub 2009 Mar 5.PMID: 19265175 [PubMed - in process]Related articles

    14.

    The biology of interleukin-2 efficacy in the treatment of patients with renal cell carcinoma.

    Romo de Vivar Chavez A, de Vera ME, Liang X, Lotze MT.

    Med Oncol. 2009;26 Suppl 1:3-12. Epub 2009 Jan 16. Review.PMID: 19148593 [PubMed - indexed for MEDLINE]Related articles

    15.

    Not just nuclear proteins: 'novel' autophagy cancer treatment targets - p53 and HMGB1.

    Livesey KM, Tang D, Zeh HJ, Lotze MT.

    Curr Opin Investig Drugs. 2008 Dec;9(12):1259-63. No abstract available. PMID: 19037832 [PubMed - indexed for MEDLINE]Related articles

    16.

    Focus on FOCIS: interleukin 2 treatment associated autoimmunity.

    Moschos SJ, Mandic M, Kirkwood JM, Storkus WJ, Lotze MT.

    Clin Immunol. 2008 May;127(2):123-9. Review.PMID: 18405863 [PubMed - indexed for MEDLINE]Related articles

    17.

    A nexus of science and clinical immunology: the Federation of Clinical Immunology Societies and the FOCIS Centers of Excellence.

    Lotze MT, Nepom GT.

    Clin Immunol. 2008 May;127(2):119-20. No abstract available. PMID: 18405861 [PubMed - indexed for MEDLINE]Related articles

    18.

    Coordinate NF-kappaB and STAT1 activation promotes development of myeloid type 1 dendritic cells.

    Vakkila J, Demarco RA, Lotze MT.

    Scand J Immunol. 2008 Mar;67(3):260-9.PMID: 18261039 [PubMed - indexed for MEDLINE]Related articles

    19.

    Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis.

    Ostberg T, Wähämaa H, Palmblad K, Ito N, Stridh P, Shoshan M, Lotze MT, Harris HE, Andersson U.

    Arthritis Res Ther. 2008;10(1):R1. Epub 2008 Jan 7.PMID: 18179697 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Detecting DNA: getting and begetting cancer.

    Farkas AM, Kilgore TM, Lotze MT.

    Curr Opin Investig Drugs. 2007 Dec;8(12):981-6. Review. No abstract available. PMID: 18058568 [PubMed - indexed for MEDLINE]Related articles

    21.

    Eosinophils induce DC maturation, regulating immunity.

    Lotfi R, Lotze MT.

    J Leukoc Biol. 2008 Mar;83(3):456-60. Epub 2007 Nov 8.PMID: 17991762 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity.

    Lotze MT, Zeh HJ, Rubartelli A, Sparvero LJ, Amoscato AA, Washburn NR, Devera ME, Liang X, Tör M, Billiar T.

    Immunol Rev. 2007 Dec;220:60-81. Review.PMID: 17979840 [PubMed - indexed for MEDLINE]Related articles

    23.

    A life in passing: Jonathan Gray.

    Lotze MT, Gray J.

    J Transl Med. 2007 Oct 30;5:54. No abstract available. PMID: 17971233 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate.

    Zetterström CK, Jiang W, Wähämaa H, Ostberg T, Aveberger AC, Schierbeck H, Lotze MT, Andersson U, Pisetsky DS, Erlandsson Harris H.

    J Leukoc Biol. 2008 Jan;83(1):31-8. Epub 2007 Oct 3.PMID: 17913975 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Induction of peripheral tolerance by local delivery of dendritic cell progenitors to cardiac allografts in a murine heterotopic heart transplantation model.

    Hikawa H, Lotze MT, Rosenblum WD.

    Gen Thorac Cardiovasc Surg. 2007 Aug;55(8):307-14.PMID: 17867275 [PubMed - indexed for MEDLINE]Related articles

    26.

    Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox.

    Rubartelli A, Lotze MT.

    Trends Immunol. 2007 Oct;28(10):429-36. Epub 2007 Sep 12.PMID: 17845865 [PubMed - indexed for MEDLINE]Related articles

    27.

    Interleukin-12: biological properties and clinical application.

    Del Vecchio M, Bajetta E, Canova S, Lotze MT, Wesa A, Parmiani G, Anichini A.

    Clin Cancer Res. 2007 Aug 15;13(16):4677-85. Review.PMID: 17699845 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    High mobility group box I (HMGB1) release from tumor cells after treatment: implications for development of targeted chemoimmunotherapy.

    Dong Xda E, Ito N, Lotze MT, Demarco RA, Popovic P, Shand SH, Watkins S, Winikoff S, Brown CK, Bartlett DL, Zeh HJ 3rd.

    J Immunother. 2007 Sep;30(6):596-606.PMID: 17667523 [PubMed - indexed for MEDLINE]Related articles

    29.

    Report on the ISBTC mini-symposium on biologic effects of targeted therapeutics.

    Atkins MB, Carbone D, Coukos G, Dhodapkar M, Ernstoff MS, Finke J, Gajewski TF, Gollob J, Lotze MT, Storkus W, Weiner LM.

    J Immunother. 2007 Sep;30(6):577-90. Review.PMID: 17667521 [PubMed - indexed for MEDLINE]Related articles

    30.

    Systemic inflammation and remote organ injury following trauma require HMGB1.

    Levy RM, Mollen KP, Prince JM, Kaczorowski DJ, Vallabhaneni R, Liu S, Tracey KJ, Lotze MT, Hackam DJ, Fink MP, Vodovotz Y, Billiar TR.

    Am J Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1538-44. Epub 2007 Jul 25.PMID: 17652366 [PubMed - indexed for MEDLINE]Related articles

    31.

    Masquerader: high mobility group box-1 and cancer.

    Ellerman JE, Brown CK, de Vera M, Zeh HJ, Billiar T, Rubartelli A, Lotze MT.

    Clin Cancer Res. 2007 May 15;13(10):2836-48. Review.PMID: 17504981 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Damage associated molecular pattern molecules.

    Lotze MT, Deisseroth A, Rubartelli A.

    Clin Immunol. 2007 Jul;124(1):1-4. Epub 2007 Apr 30. No abstract available. PMID: 17468050 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Cancer gene therapy: the power of negative thinking.

    Lotze MT.

    Gene Ther. 2006 Feb;13(3):191-3. No abstract available. PMID: 17243202 [PubMed - indexed for MEDLINE]Related articles

    34.

    Eosinophilic granulocytes and damage-associated molecular pattern molecules (DAMPs): role in the inflammatory response within tumors.

    Lotfi R, Lee JJ, Lotze MT.

    J Immunother. 2007 Jan;30(1):16-28. Review.PMID: 17198080 [PubMed - indexed for MEDLINE]Related articles

    35.

    Multianalyte profiling of serum cytokines for detection of pancreatic cancer.

    Zeh HJ, Winikoff S, Landsittel DP, Gorelik E, Marrangoni AM, Velikokhatnaya L, Winans MT, Lee K, Moser A, Bartlett D, Lotze MT, Siegfried JM, Whitcomb D, Papacristou G, Slivka A, Bigbee WL, Lokshin AE.

    Cancer Biomark. 2005;1(6):259-69. Erratum in: Cancer Biomark. 2006;2(3-4):175. Papacristou, G [added]. PMID: 17192050 [PubMed - indexed for MEDLINE]Related articles

    36.

    High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists.

    Popovic PJ, DeMarco R, Lotze MT, Winikoff SE, Bartlett DL, Krieg AM, Guo ZS, Brown CK, Tracey KJ, Zeh HJ 3rd.

    J Immunol. 2006 Dec 15;177(12):8701-7.PMID: 17142771 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    In vivo expansion of two distinct dendritic cells in mouse livers and its impact on liver immune regulation.

    Wang Y, Zheng N, Lu Z, Wu W, Wang L, Nakao A, Lotze MT, Langer CE, Fung JJ, Qian S, Lu L.

    Liver Transpl. 2006 Dec;12(12):1850-61.PMID: 17133587 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury.

    Tsung A, Zheng N, Jeyabalan G, Izuishi K, Klune JR, Geller DA, Lotze MT, Lu L, Billiar TR.

    J Leukoc Biol. 2007 Jan;81(1):119-28. Epub 2006 Oct 24.PMID: 17062605 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Cytolytic cells induce HMGB1 release from melanoma cell lines.

    Ito N, DeMarco RA, Mailliard RB, Han J, Rabinowich H, Kalinski P, Stolz DB, Zeh HJ 3rd, Lotze MT.

    J Leukoc Biol. 2007 Jan;81(1):75-83. Epub 2006 Sep 12.PMID: 16968820 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Rapid flow cytometric measurement of cytokine-induced phosphorylation pathways [CIPP] in human peripheral blood leukocytes.

    Montag DT, Lotze MT.

    Clin Immunol. 2006 Nov;121(2):215-26. Epub 2006 Sep 7.PMID: 16959540 [PubMed - indexed for MEDLINE]Related articles

    41.

    Cancer genomics: the unknown unknowns.

    Lotze MT, Yu Y.

    Curr Opin Investig Drugs. 2006 Jun;7(6):497-500. No abstract available. PMID: 16784019 [PubMed - indexed for MEDLINE]Related articles

    42.

    Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury.

    Izuishi K, Tsung A, Jeyabalan G, Critchlow ND, Li J, Tracey KJ, Demarco RA, Lotze MT, Fink MP, Geller DA, Billiar TR.

    J Immunol. 2006 Jun 15;176(12):7154-8.PMID: 16751357 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    Successful simultaneous measurement of cell membrane and cytokine induced phosphorylation pathways [CIPP] in human peripheral blood mononuclear cells.

    Montag DT, Lotze MT.

    J Immunol Methods. 2006 Jun 30;313(1-2):48-60. Epub 2006 May 2.PMID: 16716344 [PubMed - indexed for MEDLINE]Related articles

    44.

    Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: a major nosologic difference with adult tumors.

    Vakkila J, Jaffe R, Michelow M, Lotze MT.

    Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2049-54.PMID: 16609014 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Evidence of the capability of the CMV enhancer to activate in trans gene expression in mammalian cells.

    D'Aiuto L, De Marco R, Edward N, Rizzo A, Chaillet JR, Montecalvo A, Lotze MT, Gambotto A.

    DNA Cell Biol. 2006 Mar;25(3):171-80.PMID: 16569196 [PubMed - indexed for MEDLINE]Related articles

    46.

    Importance of C16 ceramide accumulation during apoptosis in prostate cancer cells.

    Eto M, Bennouna J, Hunter OC, Lotze MT, Amoscato AA.

    Int J Urol. 2006 Feb;13(2):148-56.PMID: 16563140 [PubMed - indexed for MEDLINE]Related articles

    47.

    Mechanistic insights into achievement of cardiac allograft long-term survival by treatment with immature dendritic cells and sub-dose sirolimus.

    Tao R, Wang L, Chen CH, Wang SH, Demarco RA, Lotze MT, Thai NL, Fung JJ, Lu L, Qian S.

    J Heart Lung Transplant. 2006 Mar;25(3):310-9. Epub 2006 Jan 25.PMID: 16507425 [PubMed - indexed for MEDLINE]Related articles

    49.

    Feature Selection for Classification of SELDI-TOF-MS Proteomic Profiles.

    Hauskrecht M, Pelikan R, Malehorn DE, Bigbee WL, Lotze MT, Zeh HJ, Whitcomb DC, Lyons-Weiler J.

    Appl Bioinformatics. 2005;4(4):227-46.PMID: 16309341 [PubMed - in process]Related articles

    50.

    Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells.

    Tsung A, Hoffman RA, Izuishi K, Critchlow ND, Nakao A, Chan MH, Lotze MT, Geller DA, Billiar TR.

    J Immunol. 2005 Dec 1;175(11):7661-8.PMID: 16301676 [PubMed - indexed for MEDLINE]Related articlesFree article

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