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A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding.
Ko ER, Ko D, Chen C, Lipsick JS.
Mol Cancer. 2008 Oct 7;7:77.PMID: 18840288 [PubMed - indexed for MEDLINE]Related articlesFree article
Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex.
Wen H, Andrejka L, Ashton J, Karess R, Lipsick JS.
Genes Dev. 2008 Mar 1;22(5):601-14.PMID: 18316477 [PubMed - indexed for MEDLINE]Related articlesFree article
Loss of Drosophila Myb interrupts the progression of chromosome condensation.
Manak JR, Wen H, Van T, Andrejka L, Lipsick JS.
Nat Cell Biol. 2007 May;9(5):581-7. Epub 2007 Apr 22.PMID: 17450131 [PubMed - indexed for MEDLINE]Related articles
Myb proteins inhibit fibroblast transformation by v-Rel.
Fu SL, Ganter B, Lipsick JS.
Mol Cancer. 2006 Nov 2;5:54.PMID: 17081304 [PubMed - indexed for MEDLINE]Related articlesFree article
v-Myb represses the transcription of Ets-2.
Wang DM, Sevcikova S, Wen H, Roberts S, Lipsick JS.
Oncogene. 2007 Feb 22;26(8):1238-44. Epub 2006 Aug 14.PMID: 16909100 [PubMed - indexed for MEDLINE]Related articles
synMuv verite--Myb comes into focus.
Lipsick JS.
Genes Dev. 2004 Dec 1;18(23):2837-44. Review. No abstract available. PMID: 15574590 [PubMed - indexed for MEDLINE]Related articlesFree article
Functional evolution of the vertebrate Myb gene family: B-Myb, but neither A-Myb nor c-Myb, complements Drosophila Myb in hemocytes.
Davidson CJ, Tirouvanziam R, Herzenberg LA, Lipsick JS.
Genetics. 2005 Jan;169(1):215-29. Epub 2004 Oct 16.PMID: 15489525 [PubMed - indexed for MEDLINE]Related articlesFree article
Fluorescence-activated cell sorting (FACS) of Drosophila hemocytes reveals important functional similarities to mammalian leukocytes.
Tirouvanziam R, Davidson CJ, Lipsick JS, Herzenberg LA.
Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2912-7. Epub 2004 Feb 19.PMID: 14976247 [PubMed - indexed for MEDLINE]Related articlesFree article
Role for a Drosophila Myb-containing protein complex in site-specific DNA replication.
Beall EL, Manak JR, Zhou S, Bell M, Lipsick JS, Botchan MR.
Nature. 2002 Dec 19-26;420(6917):833-7.PMID: 12490953 [PubMed - indexed for MEDLINE]Related articles
Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability.
Manak JR, Mitiku N, Lipsick JS.
Proc Natl Acad Sci U S A. 2002 May 28;99(11):7438-43.PMID: 12032301 [PubMed - indexed for MEDLINE]Related articlesFree article
Mutational analysis of the transcriptional activation domains of v-Myb.
Wang DM, Lipsick JS.
Oncogene. 2002 Feb 28;21(10):1611-5.PMID: 11896590 [PubMed - indexed for MEDLINE]Related articlesFree article
Functional evolution of the Myb oncogene family.
Lipsick JS, Manak J, Mitiku N, Chen CK, Fogarty P, Guthrie E.
Blood Cells Mol Dis. 2001 Mar-Apr;27(2):456-8.PMID: 11259167 [PubMed - indexed for MEDLINE]Related articles
BS69, an adenovirus E1A-associated protein, inhibits the transcriptional activity of c-Myb.
Ladendorff NE, Wu S, Lipsick JS.
Oncogene. 2001 Jan 4;20(1):125-32.PMID: 11244510 [PubMed - indexed for MEDLINE]Related articlesFree article
Transcriptional activation by the myb proteins requires a specific local promoter structure.
Ganter B, Chao ST, Lipsick JS.
FEBS Lett. 1999 Nov 5;460(3):401-10. Review.PMID: 10556506 [PubMed - indexed for MEDLINE]Related articles
Transformation by v-Myb.
Lipsick JS, Wang DM.
Oncogene. 1999 May 13;18(19):3047-55. Review.PMID: 10378700 [PubMed - indexed for MEDLINE]Related articlesFree article
Transcriptional regulation by the carboxyl terminus of c-Myb depends upon both the Myb DNA-binding domain and the DNA recognition site.
Dubendorff JW, Lipsick JS.
Oncogene. 1999 Jun 10;18(23):3452-60.PMID: 10376523 [PubMed - indexed for MEDLINE]Related articlesFree article
Functional analysis of carboxy-terminal deletion mutants of c-Myb.
Wang DM, Dubendorff JW, Woo CH, Lipsick JS.
J Virol. 1999 Jul;73(7):5875-86.PMID: 10364339 [PubMed - indexed for MEDLINE]Related articlesFree article
Myb and oncogenesis.
Ganter B, Lipsick JS.
Adv Cancer Res. 1999;76:21-60. Review. No abstract available. PMID: 10218098 [PubMed - indexed for MEDLINE]Related articles
Overexpression of an alternatively spliced form of c-Myb results in increases in transactivation and transforms avian myelomonoblasts.
Woo CH, Sopchak L, Lipsick JS.
J Virol. 1998 Aug;72(8):6813-21.PMID: 9658130 [PubMed - indexed for MEDLINE]Related articlesFree article
Myb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes.
Ohi R, Feoktistova A, McCann S, Valentine V, Look AT, Lipsick JS, Gould KL.
Mol Cell Biol. 1998 Jul;18(7):4097-108. Erratum in: Mol Cell Biol 1998 Oct;18(10):6164. PMID: 9632794 [PubMed - indexed for MEDLINE]Related articlesFree article
D-type cyclins repress transcriptional activation by the v-Myb but not the c-Myb DNA-binding domain.
Ganter B, Fu S, Lipsick JS.
EMBO J. 1998 Jan 2;17(1):255-68.PMID: 9427759 [PubMed - indexed for MEDLINE]Related articlesFree article
Myb binding sites within the N-ras promoter repress transcription.
Oncogene. 1997 Jul 10;15(2):193-202.PMID: 9244354 [PubMed - indexed for MEDLINE]Related articlesFree article
Cells transformed by a v-Myb-estrogen receptor fusion differentiate into multinucleated giant cells.
Engelke U, Wang DM, Lipsick JS.
J Virol. 1997 May;71(5):3760-6.PMID: 9094651 [PubMed - indexed for MEDLINE]Related articlesFree article
Constitutive expression of full-length c-Myb transforms avian cells characteristic of both the monocytic and granulocytic lineages.
Fu SL, Lipsick JS.
Cell Growth Differ. 1997 Jan;8(1):35-45.PMID: 8993832 [PubMed - indexed for MEDLINE]Related articlesFree article
FAETL motif required for leukemic transformation by v-Myb.
J Virol. 1996 Aug;70(8):5600-10.PMID: 8764074 [PubMed - indexed for MEDLINE]Related articlesFree article
One billion years of Myb.
Oncogene. 1996 Jul 18;13(2):223-35. Review.PMID: 8710361 [PubMed - indexed for MEDLINE]Related articles
Dissociation of transcriptional activation and oncogenic transformation by v-Myb.
Chen RH, Fields S, Lipsick JS.
Oncogene. 1995 Nov 2;11(9):1771-9.PMID: 7478605 [PubMed - indexed for MEDLINE]Related articles
By-pass of TPA-induced differentiation and cell cycle arrest by the c-Myb DNA-binding domain.
Engelke U, Smarda J, Lipsick JS.
Oncogene. 1995 Aug 17;11(4):735-41.PMID: 7651737 [PubMed - indexed for MEDLINE]Related articles
Weak transcriptional activation is sufficient for transformation by v-Myb.
Engelke U, Whittaker L, Lipsick JS.
Virology. 1995 Apr 20;208(2):467-77.PMID: 7747419 [PubMed - indexed for MEDLINE]Related articles
Mutations in the DNA-binding and transcriptional activation domains of v-Myb cooperate in transformation.
Dini PW, Eltman JT, Lipsick JS.
J Virol. 1995 Apr;69(4):2515-24.PMID: 7884901 [PubMed - indexed for MEDLINE]Related articlesFree article
Transformation of myelomonocytic cells by the avian myeloblastosis virus is determined by the v-myb oncogene, not by the unique long terminal repeats of the virus.
Engelke U, Lipsick JS.
J Virol. 1994 Apr;68(4):2752-5.PMID: 8139052 [PubMed - indexed for MEDLINE]Related articlesFree article
c-Myb prevents TPA-induced differentiation and cell death in v-Myb transformed monoblasts.
Smarda J, Lipsick JS.
Oncogene. 1994 Jan;9(1):237-45.PMID: 8302585 [PubMed - indexed for MEDLINE]Related articles
Dicistronic selection for nuclear proteins in living animal cells.
Gene. 1993 Dec 27;137(1):145-9.PMID: 8282197 [PubMed - indexed for MEDLINE]Related articles
Oncogenic truncation of the first repeat of c-Myb decreases DNA binding in vitro and in vivo.
Dini PW, Lipsick JS.
Mol Cell Biol. 1993 Dec;13(12):7334-48.PMID: 8246954 [PubMed - indexed for MEDLINE]Related articlesFree article
Individual repeats of Drosophila Myb can function in transformation by v-Myb.
Bin X, Lipsick JS.
J Virol. 1993 Dec;67(12):7332-9.PMID: 8230457 [PubMed - indexed for MEDLINE]Related articlesFree article
c-Myb and v-Myb are differentially phosphorylated by p42mapk in vitro.
Aziz N, Wu J, Dubendorff JW, Lipsick JS, Sturgill TW, Bender TP.
Oncogene. 1993 Aug;8(8):2259-65.PMID: 8336948 [PubMed - indexed for MEDLINE]Related articles
Differential transcriptional activation by v-myb and c-myb in animal cells and Saccharomyces cerevisiae.
Chen RH, Lipsick JS.
Mol Cell Biol. 1993 Jul;13(7):4423-31.PMID: 8321242 [PubMed - indexed for MEDLINE]Related articlesFree article
Carboxy-terminal elements of c-Myb negatively regulate transcriptional activation in cis and in trans.
Dubendorff JW, Whittaker LJ, Eltman JT, Lipsick JS.
Genes Dev. 1992 Dec;6(12B):2524-35.PMID: 1340467 [PubMed - indexed for MEDLINE]Related articlesFree article
Protein truncation is not required for c-myb proto-oncogene activity in neuroretina cells.
Garrido C, Grässer F, Lipsick JS, Stehelin D, Saule S.
J Virol. 1992 Nov;66(11):6773-6.PMID: 1404616 [PubMed - indexed for MEDLINE]Related articlesFree article
A highly conserved cysteine in the v-Myb DNA-binding domain is essential for transformation and transcriptional trans-activation.
Grässer FA, LaMontagne K, Whittaker L, Stohr S, Lipsick JS.
Oncogene. 1992 May;7(5):1005-9.PMID: 1570148 [PubMed - indexed for MEDLINE]Related articles
Expression of the CD4 gene requires a Myb transcription factor.
Siu G, Wurster AL, Lipsick JS, Hedrick SM.
Mol Cell Biol. 1992 Apr;12(4):1592-604.PMID: 1347906 [PubMed - indexed for MEDLINE]Related articlesFree article
The Myb DNA-binding domain is highly conserved in Dictyostelium discoideum.
Stober-Grässer U, Brydolf B, Bin X, Grässer F, Firtel RA, Lipsick JS.
Oncogene. 1992 Mar;7(3):589-96.PMID: 1549373 [PubMed - indexed for MEDLINE]Related articles
Definition of functional domains in P135gag-myb-ets and p48v-myb proteins required to maintain the response of neuroretina cells to basic fibroblast growth factor.
Garrido C, Leprince D, Lipsick JS, Stehelin D, Gospodarowicz D, Saule S.
J Virol. 1992 Jan;66(1):160-6.PMID: 1727478 [PubMed - indexed for MEDLINE]Related articlesFree article
Protein truncation is required for the activation of the c-myb proto-oncogene.
Grässer FA, Graf T, Lipsick JS.
Mol Cell Biol. 1991 Aug;11(8):3987-96.PMID: 2072904 [PubMed - indexed for MEDLINE]Related articlesFree article
Determinants of sequence-specific DNA-binding by p48v-myb.
Garcia A, LaMontagne K, Reavis D, Stober-Grässer U, Lipsick JS.
Oncogene. 1991 Feb;6(2):265-73.PMID: 2000220 [PubMed - indexed for MEDLINE]Related articles
trans activation of gene expression by v-myb.
Ibanez CE, Lipsick JS.
Mol Cell Biol. 1990 May;10(5):2285-93.PMID: 2325652 [PubMed - indexed for MEDLINE]Related articlesFree article
DNA-binding activity associated with the v-myb oncogene product is not sufficient for transformation.
Ibanez CE, Garcia A, Stober-Grässer U, Lipsick JS.
J Virol. 1988 Nov;62(11):4398-402.PMID: 2845150 [PubMed - indexed for MEDLINE]Related articlesFree article
Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation.
J Virol. 1988 Jun;62(6):1981-8.PMID: 2835503 [PubMed - indexed for MEDLINE]Related articlesFree article
Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus.
Stober-Grässer U, Lipsick JS.
J Virol. 1988 Mar;62(3):1093-6.PMID: 2828660 [PubMed - indexed for MEDLINE]Related articlesFree article
v-myb does not prevent the expression of c-myb in avian erythroblasts.
J Virol. 1987 Oct;61(10):3284-7.PMID: 3041047 [PubMed - indexed for MEDLINE]Related articlesFree article
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Mol Cancer. 2008 Oct 7; 7:77.
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