PubMed

Energy substrate metabolism among habitually violent alcoholic offenders having antisocial personality disorder.

Virkkunen M, Rissanen A, Naukkarinen H, Franssila-Kallunki A, Linnoila M, Tiihonen J.

Psychiatry Res. 2007 Apr 15;150(3):287-95. Epub 2007 Feb 20.PMID: 17316826 [PubMed - indexed for MEDLINE]Related articles

Genetic and other contributions to alcohol intake in rhesus macaques (Macaca mulatta).

Lorenz JG, Long JC, Linnoila M, Goldman D, Suomi SJ, Higley JD.

Alcohol Clin Exp Res. 2006 Mar;30(3):389-98. Erratum in: Alcohol Clin Exp Res. 2006 Jun;30(6):1091. PMID: 16499479 [PubMed - indexed for MEDLINE]Related articles

Maternal absence and stability of individual differences in CSF 5-HIAA concentrations in rhesus monkey infants.

Shannon C, Schwandt ML, Champoux M, Shoaf SE, Suomi SJ, Linnoila M, Higley JD.

Am J Psychiatry. 2005 Sep;162(9):1658-64.PMID: 16135625 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors.

Okada M, Goldman D, Linnoila M, Iwata N, Ozaki N, Northup JK.

Ann N Y Acad Sci. 2004 Oct;1025:570-7.PMID: 15542764 [PubMed - indexed for MEDLINE]Related articles

Modification of human 5-HT(2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution.

Okada M, Northup JK, Ozaki N, Russell JT, Linnoila M, Goldman D.

Mol Psychiatry. 2004 Jan;9(1):55-64.PMID: 14699441 [PubMed - indexed for MEDLINE]Related articles

Relationship between cortisol and serotonin metabolites and transporters in alcoholism [correction of alcolholism].

Heinz A, Jones DW, Bissette G, Hommer D, Ragan P, Knable M, Wellek S, Linnoila M, Weinberger DR.

Pharmacopsychiatry. 2002 Jul;35(4):127-34.PMID: 12163982 [PubMed - indexed for MEDLINE]Related articles

Early experience and serotonin transporter gene variation interact to influence primate CNS function.

Bennett AJ, Lesch KP, Heils A, Long JC, Lorenz JG, Shoaf SE, Champoux M, Suomi SJ, Linnoila MV, Higley JD.

Mol Psychiatry. 2002;7(1):118-22.PMID: 11803458 [PubMed - indexed for MEDLINE]Related articlesFree article

A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity.

Heinz A, Jones DW, Mazzanti C, Goldman D, Ragan P, Hommer D, Linnoila M, Weinberger DR.

Biol Psychiatry. 2000 Apr 1;47(7):643-9.PMID: 10745057 [PubMed - indexed for MEDLINE]Related articles

The suitability of [11C]-alpha-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [11C] and [14C] labeled tracer.

Shoaf SE, Carson RE, Hommer D, Williams WA, Higley JD, Schmall B, Herscovitch P, Eckelman WC, Linnoila M.

J Cereb Blood Flow Metab. 2000 Feb;20(2):244-52.PMID: 10698060 [PubMed - indexed for MEDLINE]Related articlesFree article

Seasonal variation in CSF 5-HIAA concentrations in male rhesus macaques.

Zajicek KB, Price CS, Shoaf SE, Mehlman PT, Suomi SJ, Linnoila M, Higley JD.

Neuropsychopharmacology. 2000 Mar;22(3):240-50.PMID: 10693151 [PubMed - indexed for MEDLINE]Related articlesFree article

CSF 5-HIAA and nighttime activity in free-ranging primates.

Mehlman PT, Westergaard GC, Hoos BJ, Sallee FR, Marsh S, Suomi SJ, Linnoila M, Higley JD.

Neuropsychopharmacology. 2000 Feb;22(2):210-8.PMID: 10649833 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotype influences in vivo dopamine transporter availability in human striatum.

Heinz A, Goldman D, Jones DW, Palmour R, Hommer D, Gorey JG, Lee KS, Linnoila M, Weinberger DR.

Neuropsychopharmacology. 2000 Feb;22(2):133-9.PMID: 10649826 [PubMed - indexed for MEDLINE]Related articlesFree article

Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations.

Heinz A, Weingartner H, George D, Hommer D, Wolkowitz OM, Linnoila M.

Psychiatry Res. 1999 Dec 20;89(2):97-106.PMID: 10646828 [PubMed - indexed for MEDLINE]Related articles

Plasma total cholesterol concentrations do not predict cerebrospinal fluid neurotransmitter metabolites: implications for the biophysical role of highly unsaturated fatty acids.

Hibbeln JR, Umhau JC, George DT, Shoaf SE, Linnoila M, Salem N Jr.

Am J Clin Nutr. 2000 Jan;71(1 Suppl):331S-8S.PMID: 10617992 [PubMed - indexed for MEDLINE]Related articlesFree article

Oral self-administration of ethanol, phencyclidine, methadone, pentobarbital and quinine in rhesus monkeys.

Vivian JA, Liang YJ, Higley JD, Linnoila M, Woods JH.

Psychopharmacology (Berl). 1999 Nov;147(2):113-24.PMID: 10591878 [PubMed - indexed for MEDLINE]Related articles

HTR2C Cys23Ser polymorphism in relation to CSF monoamine metabolite concentrations and DSM-III-R psychiatric diagnoses.

Lappalainen J, Long JC, Virkkunen M, Ozaki N, Goldman D, Linnoila M.

Biol Psychiatry. 1999 Sep 15;46(6):821-6.PMID: 10494451 [PubMed - indexed for MEDLINE]Related articles

Identification of four variants in the tryptophan hydroxylase promoter and association to behavior.

Rotondo A, Schuebel K, Bergen A, Aragon R, Virkkunen M, Linnoila M, Goldman D, Nielsen D.

Mol Psychiatry. 1999 Jul;4(4):360-8.PMID: 10483053 [PubMed - indexed for MEDLINE]Related articles

Oral ethanol self-administration in rhesus monkeys: behavioral and neurochemical correlates.

Vivian JA, Higley JD, Linnoila M, Woods JH.

Alcohol Clin Exp Res. 1999 Aug;23(8):1352-61.PMID: 10470978 [PubMed - indexed for MEDLINE]Related articles

Salivary prolactin as a marker for central serotonin turnover.

Lindell SG, Suomi SJ, Shoaf S, Linnoila M, Higley JD.

Biol Psychiatry. 1999 Aug 15;46(4):568-72.PMID: 10459408 [PubMed - indexed for MEDLINE]Related articles

Coupling efficiency of brain beta-adrenergic receptors to Gs protein in suicide, alcoholism and control subjects.

Gurguis GN, Turkka J, Laruelle M, Kleinman J, Linnoila M.

Psychopharmacology (Berl). 1999 Jul;145(1):31-8.PMID: 10445370 [PubMed - indexed for MEDLINE]Related articles

Autosomal, mitochondrial, and Y chromosome DNA variation in Finland: evidence for a male-specific bottleneck.

Kittles RA, Bergen AW, Urbanek M, Virkkunen M, Linnoila M, Goldman D, Long JC.

Am J Phys Anthropol. 1999 Apr;108(4):381-99.PMID: 10229384 [PubMed - indexed for MEDLINE]Related articles

Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers.

Williams WA, Shoaf SE, Hommer D, Rawlings R, Linnoila M.

J Neurochem. 1999 Apr;72(4):1641-7.PMID: 10098872 [PubMed - indexed for MEDLINE]Related articles

Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits.

Kittles RA, Long JC, Bergen AW, Eggert M, Virkkunen M, Linnoila M, Goldman D.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4204-9.PMID: 10097188 [PubMed - indexed for MEDLINE]Related articlesFree article

No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive-compulsive disorder, anorexia nervosa, and alcoholism.

Han L, Nielsen DA, Rosenthal NE, Jefferson K, Kaye W, Murphy D, Altemus M, Humphries J, Cassano G, Rotondo A, Virkkunen M, Linnoila M, Goldman D.

Biol Psychiatry. 1999 Mar 1;45(5):615-9.PMID: 10088048 [PubMed - indexed for MEDLINE]Related articles

Buspirone treatment of alcoholism: age of onset, and cerebrospinal fluid 5-hydroxyindolacetic acid and homovanillic acid concentrations, but not medication treatment, predict return to drinking.

George DT, Rawlings R, Eckardt MJ, Phillips MJ, Shoaf SE, Linnoila M.

Alcohol Clin Exp Res. 1999 Feb;23(2):272-8.PMID: 10069556 [PubMed - indexed for MEDLINE]Related articles

The combined effects of chronic ethanol/desipramine treatment on beta-adrenoceptor density and coupling efficiency in rat brain.

Gurguis GN, Turkka J, Karanian J, Linnoila M.

Eur J Pharmacol. 1998 Dec 18;363(2-3):241-51.PMID: 9881595 [PubMed - indexed for MEDLINE]Related articles

Linkage of antisocial alcoholism to the serotonin 5-HT1B receptor gene in 2 populations.

Lappalainen J, Long JC, Eggert M, Ozaki N, Robin RW, Brown GL, Naukkarinen H, Virkkunen M, Linnoila M, Goldman D.

Arch Gen Psychiatry. 1998 Nov;55(11):989-94.PMID: 9819067 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced central serotonin transporters in alcoholism.

Heinz A, Ragan P, Jones DW, Hommer D, Williams W, Knable MB, Gorey JG, Doty L, Geyer C, Lee KS, Coppola R, Weinberger DR, Linnoila M.

Am J Psychiatry. 1998 Nov;155(11):1544-9.PMID: 9812115 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of isolation-rearing on voluntary consumption of ethanol, sucrose and saccharin solutions in Fawn Hooded and Wistar rats.

Hall FS, Huang S, Fong GW, Pert A, Linnoila M.

Psychopharmacology (Berl). 1998 Oct;139(3):210-6.PMID: 9784075 [PubMed - indexed for MEDLINE]Related articles

Effects of isolation-rearing on locomotion, anxiety and responses to ethanol in Fawn Hooded and Wistar rats.

Hall FS, Huang S, Fong GW, Pert A, Linnoila M.

Psychopharmacology (Berl). 1998 Oct;139(3):203-9.PMID: 9784074 [PubMed - indexed for MEDLINE]Related articles

Role of the serotonin transporter promoter polymorphism in anxiety-related traits.

Mazzanti CM, Lappalainen J, Long JC, Bengel D, Naukkarinen H, Eggert M, Virkkunen M, Linnoila M, Goldman D.

Arch Gen Psychiatry. 1998 Oct;55(10):936-40.PMID: 9783565 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain serotonin synthesis rates in rhesus monkeys determined by [11C]alpha-methyl-L-tryptophan and positron emission tomography compared to CSF 5-hydroxyindole-3-acetic acid concentrations.

Shoaf SE, Carson R, Hommer D, Williams W, Higley JD, Schmall B, Herscovitch P, Eckelman W, Linnoila M.

Neuropsychopharmacology. 1998 Nov;19(5):345-53.PMID: 9778657 [PubMed - indexed for MEDLINE]Related articlesFree article

A replication study of violent and nonviolent subjects: cerebrospinal fluid metabolites of serotonin and dopamine are predicted by plasma essential fatty acids.

Hibbeln JR, Umhau JC, Linnoila M, George DT, Ragan PW, Shoaf SE, Vaughan MR, Rawlings R, Salem N Jr.

Biol Psychiatry. 1998 Aug 15;44(4):243-9.PMID: 9715355 [PubMed - indexed for MEDLINE]Related articles

Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics.

Hibbeln JR, Linnoila M, Umhau JC, Rawlings R, George DT, Salem N Jr.

Biol Psychiatry. 1998 Aug 15;44(4):235-42.PMID: 9715354 [PubMed - indexed for MEDLINE]Related articles

Mutation screening of the 5-hydroxytryptamine7 receptor gene among Finnish alcoholics and controls.

Pesonen U, Koulu M, Bergen A, Eggert M, Naukkarinen H, Virkkunen M, Linnoila M, Goldman D.

Psychiatry Res. 1998 Feb 27;77(3):139-45.PMID: 9707296 [PubMed - indexed for MEDLINE]Related articles

In vivo association between alcohol intoxication, aggression, and serotonin transporter availability in nonhuman primates.

Heinz A, Higley JD, Gorey JG, Saunders RC, Jones DW, Hommer D, Zajicek K, Suomi SJ, Lesch KP, Weinberger DR, Linnoila M.

Am J Psychiatry. 1998 Aug;155(8):1023-8.PMID: 9699688 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a naturally occurring Pro15-Ser15 substitution in the serotonin5A receptor gene in alcoholics and healthy volunteers.

Iwata N, Virkkunen M, Linnoila M, Goldman D.

Brain Res Mol Brain Res. 1998 Jul 15;58(1-2):217-20.PMID: 9685650 [PubMed - indexed for MEDLINE]Related articles

A tryptophan hydroxylase gene marker for suicidality and alcoholism.

Nielsen DA, Virkkunen M, Lappalainen J, Eggert M, Brown GL, Long JC, Goldman D, Linnoila M.

Arch Gen Psychiatry. 1998 Jul;55(7):593-602.PMID: 9672049 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of serotonin and metergoline on 125[I]-iodocyanopindolol binding parameters to beta-adrenergic receptors in rat brain.

Gurguis GN, Turkka J, Linnoila M.

Eur Neuropsychopharmacol. 1998 May;8(2):131-40.PMID: 9619692 [PubMed - indexed for MEDLINE]Related articles

Low central nervous system serotonergic activity is traitlike and correlates with impulsive behavior. A nonhuman primate model investigating genetic and environmental influences on neurotransmission.

Higley JD, Linnoila M.

Ann N Y Acad Sci. 1997 Dec 29;836:39-56. Review.PMID: 9616793 [PubMed - indexed for MEDLINE]Related articles

Dual origins of Finns revealed by Y chromosome haplotype variation.

Kittles RA, Perola M, Peltonen L, Bergen AW, Aragon RA, Virkkunen M, Linnoila M, Goldman D, Long JC.

Am J Hum Genet. 1998 May;62(5):1171-9.PMID: 9545401 [PubMed - indexed for MEDLINE]Related articlesFree article

The serotonin reuptake inhibitor sertraline reduces excessive alcohol consumption in nonhuman primates: effect of stress.

Higley J, Hasert M, Suomi S, Linnoila M.

Neuropsychopharmacology. 1998 Jun;18(6):431-43.PMID: 9571652 [PubMed - indexed for MEDLINE]Related articlesFree article

Fluoxetine normalizes increased cardiac vagal tone in bulimia nervosa.

Rissanen A, Naukkarinen H, Virkkunen M, Rawlings RR, Linnoila M.

J Clin Psychopharmacol. 1998 Feb;18(1):26-32.PMID: 9472839 [PubMed - indexed for MEDLINE]Related articles

Rhesus macaques with high CSF 5-HIAA concentrations exhibit early sleep onset.

Zajicek KB, Higley JD, Suomi SJ, Linnoila M.

Psychiatry Res. 1997 Nov 14;73(1-2):15-25.PMID: 9463835 [PubMed - indexed for MEDLINE]Related articles

Mu opioid receptor gene variants: lack of association with alcohol dependence.

Bergen AW, Kokoszka J, Peterson R, Long JC, Virkkunen M, Linnoila M, Goldman D.

Mol Psychiatry. 1997 Oct-Nov;2(6):490-4.PMID: 9399694 [PubMed - indexed for MEDLINE]Related articles

Effect of alcoholism on the incidence of lactate-induced panic attacks.

George DT, Lindquist T, Ragan PW, Alim T, Eckardt MJ, Linnoila M.

Biol Psychiatry. 1997 Dec 1;42(11):992-9.PMID: 9386850 [PubMed - indexed for MEDLINE]Related articles

CSF 5-HIAA, testosterone, and sociosexual behaviors in free-ranging male rhesus macaques in the mating season.

Mehlman PT, Higley JD, Fernald BJ, Sallee FR, Suomi SJ, Linnoila M.

Psychiatry Res. 1997 Sep 19;72(2):89-102.PMID: 9335200 [PubMed - indexed for MEDLINE]Related articles

Effects of m-chlorophenylpiperazine on regional brain glucose utilization: a positron emission tomographic comparison of alcoholic and control subjects.

Hommer D, Andreasen P, Rio D, Williams W, Ruttimann U, Momenan R, Zametkin A, Rawlings R, Linnoila M.

J Neurosci. 1997 Apr 15;17(8):2796-806.PMID: 9092601 [PubMed - indexed for MEDLINE]Related articlesFree article

Criminal and psychiatric histories of Finnish arsonists.

Repo E, Virkkunen M, Rawlings R, Linnoila M.

Acta Psychiatr Scand. 1997 Apr;95(4):318-23.PMID: 9150826 [PubMed - indexed for MEDLINE]Related articles

Serum ionized magnesium in chronic alcoholism: is it really decreased?

Hristova EN, Rehak NN, Cecco S, Ruddel M, Herion D, Eckardt M, Linnoila M, Elin RJ.

Clin Chem. 1997 Feb;43(2):394-9.PMID: 9023146 [PubMed - indexed for MEDLINE]Related articlesFree article