PubMed

Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation.

Funderburg NT, Mayne E, Sieg SF, Asaad R, Jiang W, Kalinowska M, Luciano AA, Stevens W, Rodriguez B, Brenchley JM, Douek DC, Lederman MM.

Blood. 2009 Oct 14. [Epub ahead of print]PMID: 19828697 [PubMed - as supplied by publisher]Related articles

Oral cyclosporin A inhibits CD4 T cell P-glycoprotein activity in HIV-infected adults initiating treatment with nucleoside reverse transcriptase inhibitors.

Hulgan T, Donahue JP, Smeaton L, Pu M, Wang H, Lederman MM, Smith K, Valdez H, Pilcher C, Haas DW; AIDS Clinical Trials Group Study A5138 Team.

Eur J Clin Pharmacol. 2009 Nov;65(11):1081-8.PMID: 19779705 [PubMed - in process]Related articles

Impaired plasmacytoid dendritic cell (PDC)-NK cell activity in viremic human immunodeficiency virus infection attributable to impairments in both PDC and NK cell function.

Conry SJ, Milkovich KA, Yonkers NL, Rodriguez B, Bernstein HB, Asaad R, Heinzel FP, Tary-Lehmann M, Lederman MM, Anthony DD.

J Virol. 2009 Nov;83(21):11175-87. Epub 2009 Aug 19.PMID: 19692459 [PubMed - in process]Related articles

Characterizing traditionally defined periodontal disease in HIV+ adults.

Vernon LT, Demko CA, Whalen CC, Lederman MM, Toossi Z, Wu M, Han YW, Weinberg A.

Community Dent Oral Epidemiol. 2009 Oct;37(5):427-37. Epub 2009 Jul 14.PMID: 19624697 [PubMed - in process]Related articlesFree article

Dose-modified oral chemotherapy in the treatment of AIDS-related non-Hodgkin's lymphoma in East Africa.

Mwanda WO, Orem J, Fu P, Banura C, Kakembo J, Onyango CA, Ness A, Reynolds S, Johnson JL, Subbiah V, Bako J, Wabinga H, Abdallah FK, Meyerson HJ, Whalen CC, Lederman MM, Black J, Ayers LW, Katongole-Mbidde E, Remick SC.

J Clin Oncol. 2009 Jul 20;27(21):3480-8. Epub 2009 May 26.PMID: 19470940 [PubMed - indexed for MEDLINE]Related articles

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.

Sereti I, Dunham RM, Spritzler J, Aga E, Proschan MA, Medvik K, Battaglia CA, Landay AL, Pahwa S, Fischl MA, Asmuth DM, Tenorio AR, Altman JD, Fox L, Moir S, Malaspina A, Morre M, Buffet R, Silvestri G, Lederman MM; ACTG 5214 Study Team.

Blood. 2009 Jun 18;113(25):6304-14. Epub 2009 Apr 20.PMID: 19380868 [PubMed - indexed for MEDLINE]Related articles

Targeting a host element as a strategy to block HIV replication: is it nice to fool with Mother Nature?

Lederman MM, Este J.

Curr Opin HIV AIDS. 2009 Mar;4(2):79-81. No abstract available. PMID: 19339944 [PubMed - indexed for MEDLINE]Related articles

Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge.

Veazey RS, Ling B, Green LC, Ribka EP, Lifson JD, Piatak M Jr, Lederman MM, Mosier D, Offord R, Hartley O.

J Infect Dis. 2009 May 15;199(10):1525-7.PMID: 19331577 [PubMed - indexed for MEDLINE]Related articles

Desensitization to type I interferon in HIV-1 infection correlates with markers of immune activation and disease progression.

Hardy GA, Sieg SF, Rodriguez B, Jiang W, Asaad R, Lederman MM, Harding CV.

Blood. 2009 May 28;113(22):5497-505. Epub 2009 Mar 19.PMID: 19299650 [PubMed - indexed for MEDLINE]Related articles

Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection.

Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM.

J Infect Dis. 2009 Apr 15;199(8):1177-85. Erratum in: J Infect Dis. 2009 Jul 1;200(1):160. PMID: 19265479 [PubMed - indexed for MEDLINE]Related articlesFree article

Topical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection.

Lederman MM, Jump R, Pilch-Cooper HA, Root M, Sieg SF.

Retrovirology. 2008 Dec 18;5:116. Review.PMID: 19094217 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of aging on T-regulatory cell frequency in HIV infection.

Tenorio AR, Spritzler J, Martinson J, Gichinga CN, Pollard RB, Lederman MM, Kalayjian RC, Landay AL.

Clin Immunol. 2009 Mar;130(3):298-303. Epub 2008 Nov 12.PMID: 19008157 [PubMed - indexed for MEDLINE]Related articles

Increased levels of human beta-defensins mRNA in sexually HIV-1 exposed but uninfected individuals.

Zapata W, Rodriguez B, Weber J, Estrada H, Quiñones-Mateu ME, Zimermman PA, Lederman MM, Rugeles MT.

Curr HIV Res. 2008 Nov;6(6):531-8.PMID: 18991618 [PubMed - indexed for MEDLINE]Related articles

Chemokine analogues show suitable stability for development as microbicides.

Cerini F, Landay A, Gichinga C, Lederman MM, Flyckt R, Starks D, Offord RE, Le Gal F, Hartley O.

J Acquir Immune Defic Syndr. 2008 Dec 15;49(5):472-6.PMID: 18989226 [PubMed - indexed for MEDLINE]Related articles

Editors' perspective and conclusions.

Lederman MM, Sereni D, Simonneau G, Voelkel NF.

AIDS. 2008 Sep;22 Suppl 3:S63-7. No abstract available. PMID: 18845924 [PubMed - indexed for MEDLINE]Related articles

Pulmonary arterial hypertension and its association with HIV infection: an overview.

Lederman MM, Sereni D, Simonneau G, Voelkel NF.

AIDS. 2008 Sep;22 Suppl 3:S1-6. Review.PMID: 18845916 [PubMed - indexed for MEDLINE]Related articles

Hepatitis C virus-specific T-cell gamma interferon and proliferative responses are more common in perihepatic lymph nodes than in peripheral blood or liver.

Moonka D, Milkovich KA, Rodriguez B, Abouljoud M, Lederman MM, Anthony DD.

J Virol. 2008 Dec;82(23):11742-8. Epub 2008 Aug 20.PMID: 18715927 [PubMed - indexed for MEDLINE]Related articlesFree article

Whither or wither microbicides?

Grant RM, Hamer D, Hope T, Johnston R, Lange J, Lederman MM, Lieberman J, Miller CJ, Moore JP, Mosier DE, Richman DD, Schooley RT, Springer MS, Veazey RS, Wainberg MA.

Science. 2008 Jul 25;321(5888):532-4.PMID: 18653884 [PubMed - indexed for MEDLINE]Related articlesFree article

The lymph node in HIV pathogenesis.

Lederman MM, Margolis L.

Semin Immunol. 2008 Jun;20(3):187-95. Epub 2008 Jul 14. Review.PMID: 18620868 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired naive and memory B-cell responsiveness to TLR9 stimulation in human immunodeficiency virus infection.

Jiang W, Lederman MM, Mohner RJ, Rodriguez B, Nedrich TM, Harding CV, Sieg SF.

J Virol. 2008 Aug;82(16):7837-45. Epub 2008 Jun 4.PMID: 18524824 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis.

Funderburg N, Luciano AA, Jiang W, Rodriguez B, Sieg SF, Lederman MM.

PLoS One. 2008 Apr 2;3(4):e1915.PMID: 18382686 [PubMed - indexed for MEDLINE]Related articlesFree article

S-phase entry leads to cell death in circulating T cells from HIV-infected persons.

Sieg SF, Bazdar DA, Lederman MM.

J Leukoc Biol. 2008 Jun;83(6):1382-7. Epub 2008 Mar 27.PMID: 18372341 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety, pharmacokinetics, and antiviral activity of HGS004, a novel fully human IgG4 monoclonal antibody against CCR5, in HIV-1-infected patients.

Lalezari J, Yadavalli GK, Para M, Richmond G, Dejesus E, Brown SJ, Cai W, Chen C, Zhong J, Novello LA, Lederman MM, Subramanian GM.

J Infect Dis. 2008 Mar 1;197(5):721-7.PMID: 18266604 [PubMed - indexed for MEDLINE]Related articles

Cohort profile: the Centers for AIDS Research Network of Integrated Clinical Systems.

Kitahata MM, Rodriguez B, Haubrich R, Boswell S, Mathews WC, Lederman MM, Lober WB, Van Rompaey SE, Crane HM, Moore RD, Bertram M, Kahn JO, Saag MS.

Int J Epidemiol. 2008 Oct;37(5):948-55. Epub 2008 Feb 8. No abstract available. PMID: 18263650 [PubMed - indexed for MEDLINE]Related articlesFree article

CCR5 and its ligands: a new axis of evil?

Lederman MM, Sieg SF.

Nat Immunol. 2007 Dec;8(12):1283-5. No abstract available. PMID: 18026077 [PubMed - indexed for MEDLINE]Related articles

Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2.

Funderburg N, Lederman MM, Feng Z, Drage MG, Jadlowsky J, Harding CV, Weinberg A, Sieg SF.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18631-5. Epub 2007 Nov 15.PMID: 18006661 [PubMed - indexed for MEDLINE]Related articlesFree article

Understanding the benign nature of SIV infection in natural hosts.

Silvestri G, Paiardini M, Pandrea I, Lederman MM, Sodora DL.

J Clin Invest. 2007 Nov;117(11):3148-54. Review.PMID: 17975656 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired induction of CD27 and CD28 predicts naive CD4 T cell proliferation defects in HIV disease.

Luciano AA, Lederman MM, Valentin-Torres A, Bazdar DA, Sieg SF.

J Immunol. 2007 Sep 15;179(6):3543-9.PMID: 17785788 [PubMed - indexed for MEDLINE]Related articlesFree article

A new approach for 'deep salvage' trials in advanced HIV infection.

Lederman MM, Miller V, Weller I, Deeks SG.

AIDS. 2007 Jul 31;21(12):1503-6. Review.PMID: 17630543 [PubMed - indexed for MEDLINE]Related articles

TLR9 stimulation drives naïve B cells to proliferate and to attain enhanced antigen presenting function.

Jiang W, Lederman MM, Harding CV, Rodriguez B, Mohner RJ, Sieg SF.

Eur J Immunol. 2007 Aug;37(8):2205-13.PMID: 17621369 [PubMed - indexed for MEDLINE]Related articles

Statins Blunt HAART-Induced CD4 T-Cell Gains but Have No Long-Term Effect on Virologic Response to HAART.

Rodriguez B, Valdez H, Mijch A, Watson K, Lederman MM, McComsey GA, Loupa CV, Woolley I.

J Int Assoc Physicians AIDS Care (Chic Ill). 2007 Sep;6(3):198-202. Epub 2007 Jun 19.PMID: 17579125 [PubMed - in process]Related articles

The virologic, immunologic, and clinical effects of interleukin 2 with potent antiretroviral therapy in patients with moderately advanced human immunodeficiency virus infection: a randomized controlled clinical trial--AIDS Clinical Trials Group 328.

Mitsuyasu R, Gelman R, Cherng DW, Landay A, Fahey J, Reichman R, Erice A, Bucy RP, Kilby JM, Lederman MM, Hamilton CD, Lertora J, White BL, Tebas P, Duliege AM, Pollard RB; AIDS Clinical Trials Group 328 Study Team.

Arch Intern Med. 2007 Mar 26;167(6):597-605.PMID: 17389292 [PubMed - indexed for MEDLINE]Related articlesFree article

TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection.

Yonkers NL, Rodriguez B, Milkovich KA, Asaad R, Lederman MM, Heeger PS, Anthony DD.

J Immunol. 2007 Apr 1;178(7):4436-44.PMID: 17372001 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.

Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM.

Blood. 2007 May 15;109(10):4272-9. Epub 2007 Feb 8.PMID: 17289812 [PubMed - indexed for MEDLINE]Related articlesFree article

Monitoring clinical trials of therapeutic vaccines in HIV infection: role of treatment interruption.

Lederman MM, Penn-Nicholson A, Stone SF, Sieg SF, Rodriguez B.

Curr Opin HIV AIDS. 2007 Jan;2(1):56-61.PMID: 19372866 [PubMed - in process]Related articles

Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment.

Bosch RJ, Wang R, Vaida F, Lederman MM, Albrecht MA.

J Acquir Immune Defic Syndr. 2006 Dec 1;43(4):433-5.PMID: 17183628 [PubMed - indexed for MEDLINE]Related articles

Slow disease progression and robust therapy-mediated CD4+ T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection.

Dion ML, Bordi R, Zeidan J, Asaad R, Boulassel MR, Routy JP, Lederman MM, Sekaly RP, Cheynier R.

Blood. 2007 Apr 1;109(7):2912-20.PMID: 17164338 [PubMed - indexed for MEDLINE]Related articlesFree article

Microbial translocation is a cause of systemic immune activation in chronic HIV infection.

Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC.

Nat Med. 2006 Dec;12(12):1365-71. Epub 2006 Nov 19.PMID: 17115046 [PubMed - indexed for MEDLINE]Related articles

Cyclosporin A provides no sustained immunologic benefit to persons with chronic HIV-1 infection starting suppressive antiretroviral therapy: results of a randomized, controlled trial of the AIDS Clinical Trials Group A5138.

Lederman MM, Smeaton L, Smith KY, Rodriguez B, Pu M, Wang H, Sevin A, Tebas P, Sieg SF, Medvik K, Margolis DM, Pollard R, Ertl HC, Valdez H.

J Infect Dis. 2006 Dec 15;194(12):1677-85. Epub 2006 Nov 2.PMID: 17109339 [PubMed - indexed for MEDLINE]Related articles

A plea for justice for jailed medical workers.

Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA.

Science. 2006 Nov 10;314(5801):924-5. Epub 2006 Oct 24. No abstract available. PMID: 17062652 [PubMed - indexed for MEDLINE]Related articlesFree article

A randomized trial of treatment interruption before optimized antiretroviral therapy for persons with drug-resistant HIV: 48-week virologic results of ACTG A5086.

Benson CA, Vaida F, Havlir DV, Downey GF, Lederman MM, Gulick RM, Glesby MJ, Wantman M, Bixby CJ, Rinehart AR, Snyder S, Wang R, Patel S, Mellors JW; ACTG A5086 Study Team.

J Infect Dis. 2006 Nov 1;194(9):1309-18. Epub 2006 Sep 22.PMID: 17041858 [PubMed - indexed for MEDLINE]Related articles

Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection.

Rodríguez B, Sethi AK, Cheruvu VK, Mackay W, Bosch RJ, Kitahata M, Boswell SL, Mathews WC, Bangsberg DR, Martin J, Whalen CC, Sieg S, Yadavalli S, Deeks SG, Lederman MM.

JAMA. 2006 Sep 27;296(12):1498-506.PMID: 17003398 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration.

Haas DW, Bartlett JA, Andersen JW, Sanne I, Wilkinson GR, Hinkle J, Rousseau F, Ingram CD, Shaw A, Lederman MM, Kim RB; Adult AIDS Clinical Trials Group.

Clin Infect Dis. 2006 Sep 15;43(6):783-6. Epub 2006 Aug 15.PMID: 16912957 [PubMed - indexed for MEDLINE]Related articles

Biology of CCR5 and its role in HIV infection and treatment.

Lederman MM, Penn-Nicholson A, Cho M, Mosier D.

JAMA. 2006 Aug 16;296(7):815-26. Review.PMID: 16905787 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV coinfection impairs CD28-mediated costimulation of hepatitis C virus-specific CD8 cells.

Yonkers NL, Rodriguez B, Post AB, Asaad R, Jones L, Lederman MM, Lehmann PV, Anthony DD.

J Infect Dis. 2006 Aug 1;194(3):391-400. Epub 2006 Jun 30.PMID: 16826489 [PubMed - indexed for MEDLINE]Related articles

Cutting edge: human beta defensin 3--a novel antagonist of the HIV-1 coreceptor CXCR4.

Feng Z, Dubyak GR, Lederman MM, Weinberg A.

J Immunol. 2006 Jul 15;177(2):782-6.PMID: 16818731 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon-alpha differentially rescues CD4 and CD8 T cells from apoptosis in HIV infection.

Rodriguez B, Lederman MM, Jiang W, Bazdar DA, Gàrate K, Harding CV, Sieg SF.

AIDS. 2006 Jun 26;20(10):1379-89.PMID: 16791012 [PubMed - indexed for MEDLINE]Related articles

Role of human beta-defensins in HIV infection.

Weinberg A, Quiñones-Mateu ME, Lederman MM.

Adv Dent Res. 2006 Apr 1;19(1):42-8. Review.PMID: 16672548 [PubMed - indexed for MEDLINE]Related articlesFree article

Microbicides and other topical strategies to prevent vaginal transmission of HIV.

Lederman MM, Offord RE, Hartley O.

Nat Rev Immunol. 2006 May;6(5):371-82. Review.PMID: 16639430 [PubMed - indexed for MEDLINE]Related articles

Gender differences in human immunodeficiency virus (HIV) RNA and CD4 cell counts among new entrants to HIV care.

Loupa CV, Rodriguez B, McComsey G, Gripshover B, Salata RA, Valdez H, Lisgaris MV, Fulton SA, Lederman MM.

Clin Microbiol Infect. 2006 Apr;12(4):389-91.PMID: 16524417 [PubMed - indexed for MEDLINE]Related articles