PubMed

Using plasma renin (PRA) testing to design follow-up drug treatment strategies in hypertensive patients already taking antirenin system drugs.

Sealey JE, Laragh JH.

Am J Hypertens. 2009 Sep;22(9):950. No abstract available. PMID: 19701164 [PubMed - in process]Related articles

Plasma Renin test-guided drug treatment algorithm for correcting patients with treated but uncontrolled hypertension: a randomized controlled trial.

Egan BM, Basile JN, Rehman SU, Davis PB, Grob CH 3rd, Riehle JF, Walters CA, Lackland DT, Merali C, Sealey JE, Laragh JH.

Am J Hypertens. 2009 Jul;22(7):792-801. Epub 2009 Apr 16.PMID: 19373213 [PubMed - indexed for MEDLINE]Related articles

Aliskiren fails to lower blood pressure in patients who have either low PRA levels or whose PRA falls insufficiently or reactively rises.

Sealey JE, Laragh JH.

Am J Hypertens. 2009 Jan;22(1):112-21. Epub 2008 Sep 18. Review.PMID: 18802434 [PubMed - indexed for MEDLINE]Related articles

It is the plasma renin activity level that counts, not stoichiometry.

Sealey JE, Laragh JH.

Hypertension. 2008 Aug;52(2):e20; author reply e21. Epub 2008 Jul 7. No abstract available. PMID: 18606895 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of angiotensin receptor blockers on ambulatory plasma Renin activity in healthy, normal subjects during unrestricted sodium intake.

Jones MR, Sealey JE, Laragh JH.

Am J Hypertens. 2007 Aug;20(8):907-16.PMID: 17679042 [PubMed - indexed for MEDLINE]Related articles

Aliskiren, the first renin inhibitor for treating hypertension: reactive renin secretion may limit its effectiveness.

Sealey JE, Laragh JH.

Am J Hypertens. 2007 May;20(5):587-97.PMID: 17485026 [PubMed - indexed for MEDLINE]Related articles

Dr. Michael H. Alderman takes the helm as editor-in-chief of the American Journal of Hypertension.

Laragh JH.

Am J Hypertens. 2006 Dec;19(12):1197-8. No abstract available. PMID: 17161762 [PubMed - indexed for MEDLINE]Related articles

Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: An analysis of findings from the VALUE trial.

Zanchetti A, Julius S, Kjeldsen S, McInnes GT, Hua T, Weber M, Laragh JH, Plat F, Battegay E, Calvo-Vargas C, Cieśliński A, Degaute JP, Holwerda NJ, Kobalava J, Pedersen OL, Rudyatmoko FP, Siamopoulos KC, Störset O.

J Hypertens. 2006 Nov;24(11):2163-8.PMID: 17053536 [PubMed - indexed for MEDLINE]Related articles

Low renin hypertensive states: perspectives, unsolved problems, future research.

Gordon RD, Laragh JH, Funder JW.

Trends Endocrinol Metab. 2005 Apr;16(3):108-13. Review.PMID: 15808808 [PubMed - indexed for MEDLINE]Related articles

A free-ranging roundtable discussion on hypertension.

Standridge JB, Sealey JE, Laragh JH, Houston MC, Gavras H, Johnson RJ, Blumenfeld JD, Brown M, Egan BM, Meltzer JI, Shimosawa T, Fujita T.

J Hum Hypertens. 2005 Apr;19(4):259-66. No abstract available. PMID: 15716983 [PubMed - indexed for MEDLINE]Related articles

Prorenin cryoactivation as a possible cause of normal renin levels in patients with primary aldosteronism.

Sealey JE, Blumenfeld J, Laragh JH.

J Hypertens. 2005 Feb;23(2):459-60; author reply 460. No abstract available. PMID: 15662236 [PubMed - indexed for MEDLINE]Related articles

Plagiarism and scientific misconduct.

Catanzaro DF, Blumenfeld JD, Laragh JH.

Am J Hypertens. 2004 Nov;17(11 Pt 1):1077. No abstract available. PMID: 15533738 [PubMed - indexed for MEDLINE]Related articles

Beyond hypertension toward guidelines for cardiovascular risk reduction.

Volpe M, Alderman MH, Furberg CD, Jackson R, Kostis JB, Laragh JH, Psaty BM, Ruilope LM.

Am J Hypertens. 2004 Nov;17(11 Pt 1):1068-74.PMID: 15533736 [PubMed - indexed for MEDLINE]Related articles

Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial.

Weber MA, Julius S, Kjeldsen SE, Brunner HR, Ekman S, Hansson L, Hua T, Laragh JH, McInnes GT, Mitchell L, Plat F, Schork MA, Smith B, Zanchetti A.

Lancet. 2004 Jun 19;363(9426):2049-51.PMID: 15207957 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide synthase inhibition accelerates the pressor response to low-dose angiotensin II, exacerbates target organ damage, and induces renin escape.

Hu L, Sealey JE, Chen R, Zhou Y, Merali C, Shi Y, Laragh JH, Catanzaro DF.

Am J Hypertens. 2004 May;17(5 Pt 1):395-403.PMID: 15110897 [PubMed - indexed for MEDLINE]Related articles

Acute vascular effects of the angiotensin II receptor antagonist olmesartan in normal subjects: relation to the renin-aldosterone system.

Resnick LM, Catanzaro D, Sealey JE, Laragh JH.

Am J Hypertens. 2004 Mar;17(3):203-8.PMID: 15001191 [PubMed - indexed for MEDLINE]Related articles

Plasma renin activity levels in hypertensive persons: their wide range and lack of suppression in diabetic and in most elderly patients.

Alderman MH, Cohen HW, Sealey JE, Laragh JH.

Am J Hypertens. 2004 Jan;17(1):1-7.PMID: 14700504 [PubMed - indexed for MEDLINE]Related articles

Optimal resources for the examination and endovascular treatment of the peripheral and visceral vascular systems. AHA Intercouncil Report on Peripheral and Visceral Angiographic and Interventional Laboratories.

Cardella JF, Casarella WJ, DeWeese JA, Dorros GM, Gray JE, Katzen BT, Laragh JH, Levin DC, Marx VM, Nickoloff EL, Pentecost MJ, Roubin GS, Martin EC; Intersociety Commission for Heart Disease Resources, American Heart Association.

J Vasc Interv Radiol. 2003 Sep;14(9 Pt 2):S517-30. No abstract available. PMID: 14514866 [PubMed]Related articles

VALUE trial: Long-term blood pressure trends in 13,449 patients with hypertension and high cardiovascular risk.

Julius S, Kjeldsen SE, Brunner H, Hansson L, Platt F, Ekman S, Laragh JH, McInnes G, Schork AM, Smith B, Weber M, Zanchetti A; VALUE Trial.

Am J Hypertens. 2003 Jul;16(7):544-8.PMID: 12850387 [PubMed - indexed for MEDLINE]Related articles

Relevance of the plasma renin hormonal control system that regulates blood pressure and sodium balance for correctly treating hypertension and for evaluating ALLHAT.

Laragh JH, Sealey JE.

Am J Hypertens. 2003 May;16(5 Pt 1):407-15. Review. No abstract available. PMID: 12745204 [PubMed - indexed for MEDLINE]Related articles

Hypertension is not all alike nor are its treatments: where would a better calcium-channel blocker fit in a modern treatment system?

Laragh JH.

Clin Cardiol. 2003 Feb;26(2 Suppl 2):II21-2. No abstract available. PMID: 12622323 [PubMed - indexed for MEDLINE]Related articles

Left ventricular mass change during treatment and outcome in patients with essential hypertension.

Koren MJ, Ulin RJ, Koren AT, Laragh JH, Devereux RB.

Am J Hypertens. 2002 Dec;15(12):1021-8.PMID: 12460696 [PubMed - indexed for MEDLINE]Related articles

Hypertension guidelines: criteria that might make them more clinically useful.

Alderman MH, Furberg CD, Kostis JB, Laragh JH, Psaty BM, Ruilope LM, Volpe M, Jackson R.

Am J Hypertens. 2002 Oct;15(10 Pt 1):917-23. Review.PMID: 12372681 [PubMed - indexed for MEDLINE]Related articles

Abstract, closing summary, and table of contents for Laragh's 25 lessons in pathophysiology and 12 clinical pearls for treating hypertension.

Laragh JH.

Am J Hypertens. 2001 Dec;14(12):1173-7. Review.PMID: 11775122 [PubMed - indexed for MEDLINE]Related articles

Management of hypertensive crises: the scientific basis for treatment decisions.

Blumenfeld JD, Laragh JH.

Am J Hypertens. 2001 Nov;14(11 Pt 1):1154-67. Review.PMID: 11724216 [PubMed - indexed for MEDLINE]Related articles

K(+) depletion and the progression of hypertensive disease or heart failure. The pathogenic role of diuretic-induced aldosterone secretion.

Laragh JH, Sealey JE.

Hypertension. 2001 Feb;37(2 Part 2):806-10. Review. No abstract available. PMID: 11230377 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma renin activity in the emergency department and its independent association with acute myocardial infarction.

Blumenfeld JD, Sealey JE, Alderman MH, Cohen H, Lappin R, Catanzaro DF, Laragh JH.

Am J Hypertens. 2000 Aug;13(8):855-63.PMID: 10950393 [PubMed - indexed for MEDLINE]Related articles

Possible role of increased blood viscosity in the hemodynamics of systemic hypertension.

Devereux RB, Case DB, Alderman MH, Pickering TG, Chien S, Laragh JH.

Am J Cardiol. 2000 May 15;85(10):1265-8. No abstract available. PMID: 10802017 [PubMed - indexed for MEDLINE]Related articles

Delayed recovery of hypertension after single dose losartan in angiotensin II-infused conscious rats.

Hu L, Catanzaro DF, Laragh JH, Sealey JE.

J Hypertens. 1999 Oct;17(10):1443-50.PMID: 10526905 [PubMed - indexed for MEDLINE]Related articles

Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.

Blumenfeld JD, Sealey JE, Mann SJ, Bragat A, Marion R, Pecker MS, Sotelo J, August P, Pickering TG, Laragh JH.

Am J Hypertens. 1999 May;12(5):451-9.PMID: 10342782 [PubMed - indexed for MEDLINE]Related articles

Appropriate regulation of renin and blood pressure in 45-kb human renin/human angiotensinogen transgenic mice.

Catanzaro DF, Chen R, Yan Y, Hu L, Sealey JE, Laragh JH.

Hypertension. 1999 Jan;33(1 Pt 2):318-22.PMID: 9931123 [PubMed - indexed for MEDLINE]Related articlesFree article

Kidney is the only source of human plasma renin in 45-kb human renin transgenic mice.

Yan Y, Chen R, Pitarresi T, Sigmund CD, Gross KW, Sealey JE, Laragh JH, Catanzaro DF.

Circ Res. 1998 Dec 14-28;83(12):1279-88.PMID: 9851945 [PubMed - indexed for MEDLINE]Related articlesFree article

Renin system analysis defines the special value of combination antihypertensive therapy using an antirenin agent (CEI) with a long-acting calcium channel blocker (CCB).

Laragh JH.

Am J Hypertens. 1998 Oct;11(10):170S-174S. Review. No abstract available. PMID: 9799052 [PubMed - indexed for MEDLINE]Related articles

Identical hemodynamic and hormonal responses to 14-day infusions of renin or angiotensin II in conscious rats.

Hu L, Catanzaro DF, Pitarresi TM, Laragh JH, Sealey JE.

J Hypertens. 1998 Sep;16(9):1285-98.PMID: 9746116 [PubMed - indexed for MEDLINE]Related articles

Appropriate regulation of human renin gene expression and secretion in 45-kb human renin transgenic mice.

Yan Y, Hu L, Chen R, Sealey JE, Laragh JH, Catanzaro DF.

Hypertension. 1998 Aug;32(2):205-14.PMID: 9719044 [PubMed - indexed for MEDLINE]Related articlesFree article

Renin system analysis: a rational method for the diagnosis and treatment of the individual patient with hypertension.

Blumenfeld JD, Laragh JH.

Am J Hypertens. 1998 Jul;11(7):894-6. No abstract available. PMID: 9683058 [PubMed - indexed for MEDLINE]Related articles

Serum sex hormone levels in postmenopausal women with hypertension.

Phillips GB, Jing TY, Laragh JH.

J Hum Hypertens. 1997 Aug;11(8):523-6.PMID: 9322834 [PubMed - indexed for MEDLINE]Related articles

Usefulness of subnormal midwall fractional shortening in predicting left ventricular exercise dysfunction in asymptomatic patients with systemic hypertension.

Schussheim AE, Devereux RB, de Simone G, Borer JS, Herrold EM, Laragh JH.

Am J Cardiol. 1997 Apr 15;79(8):1070-4.PMID: 9114766 [PubMed - indexed for MEDLINE]Related articles

Plasma renin activity: a risk factor for myocardial infarction in hypertensive patients.

Alderman MH, Ooi WL, Cohen H, Madhavan S, Sealey JE, Laragh JH.

Am J Hypertens. 1997 Jan;10(1):1-8.PMID: 9008242 [PubMed - indexed for MEDLINE]Related articles

Chronic carvedilol reduces mortality and renal damage in hypertensive stroke-prone rats.

Barone FC, Nelson AH, Ohlstein EH, Willette RN, Sealey JE, Laragh JH, Campbell WG Jr, Feuerstein GZ.

J Pharmacol Exp Ther. 1996 Nov;279(2):948-55.PMID: 8930204 [PubMed - indexed for MEDLINE]Related articles

Influence of obesity on left ventricular midwall mechanics in arterial hypertension.

de Simone G, Devereux RB, Mureddu GF, Roman MJ, Ganau A, Alderman MH, Contaldo F, Laragh JH.

Hypertension. 1996 Aug;28(2):276-83.PMID: 8707394 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma renin activity and plasma prorenin are not suppressed in hypertensives surviving to old age.

Trenkwalder P, James GD, Laragh JH, Sealey JE.

Am J Hypertens. 1996 Jul;9(7):621-7.PMID: 8806973 [PubMed - indexed for MEDLINE]Related articles

Renin and prorenin: advances and declines in methodology.

Sealey JE, Laragh JH.

Clin Chem. 1996 Jul;42(7):993-4. No abstract available. PMID: 8674211 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise renography in untreated subjects with essential hypertension.

Fine EJ, Blaufox MD, Blumenfeld JD, Laragh JH, Chun KJ, Heller SL, Bongiovanni JA.

J Nucl Med. 1996 May;37(5):838-42.PMID: 8965157 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific prorenin/renin binding (ProBP). Identification and characterization of a novel membrane site.

Sealey JE, Catanzaro DF, Lavin TN, Gahnem F, Pitarresi T, Hu LF, Laragh JH.

Am J Hypertens. 1996 May;9(5):491-502.PMID: 8735181 [PubMed - indexed for MEDLINE]Related articles

Plasma and renal prorenin/renin, renin mRNA, and blood pressure in Dahl salt-sensitive and salt-resistant rats.

Campbell WG Jr, Gahnem F, Catanzaro DF, James GD, Camargo MJ, Laragh JH, Sealey JE.

Hypertension. 1996 May;27(5):1121-33.PMID: 8621206 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of development of left ventricular hypertrophy in salt-loaded Dahl salt-sensitive rats by angiotensin II receptor inhibition.

de Simone G, Devereux RB, Camargo MJ, Wallerson DC, Sealey JE, Laragh JH.

Am J Hypertens. 1996 Mar;9(3):216-22.PMID: 8695019 [PubMed - indexed for MEDLINE]Related articles

Calcium antagonists and cardiovascular prognosis: a homogeneous group?

Laragh JH, Held C, Messerli F, Pepine C, Sleight P.

Am J Hypertens. 1996 Feb;9(2):99-109. Review. No abstract available. PMID: 8924271 [PubMed - indexed for MEDLINE]Related articles

Midwall LV mechanics in rats with or without renovascular hypertension: effect of different Na+ intakes.

De Simone G, Devereux RB, Volpe M, Camargo MJ, Wallerson DC, Laragh JH.

Am J Physiol. 1996 Feb;270(2 Pt 2):H628-37.PMID: 8779839 [PubMed - indexed for MEDLINE]Related articles

Midwall left ventricular mechanics. An independent predictor of cardiovascular risk in arterial hypertension.

de Simone G, Devereux RB, Koren MJ, Mensah GA, Casale PN, Laragh JH.

Circulation. 1996 Jan 15;93(2):259-65.PMID: 8548897 [PubMed - indexed for MEDLINE]Related articlesFree article