PubMed

Remote control of insulin secretion by fat cells in Drosophila.

Géminard C, Rulifson EJ, Léopold P.

Cell Metab. 2009 Sep;10(3):199-207.PMID: 19723496 [PubMed - in process]Related articles

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.

Vincent T, Neve EP, Johnson JR, Kukalev A, Rojo F, Albanell J, Pietras K, Virtanen I, Philipson L, Leopold PL, Crystal RG, de Herreros AG, Moustakas A, Pettersson RF, Fuxe J.

Nat Cell Biol. 2009 Aug;11(8):943-50. Epub 2009 Jul 13.PMID: 19597490 [PubMed - indexed for MEDLINE]Related articles

Virus-induced neuronal dysfunction and degeneration.

Berth SH, Leopold PL, Morfini GN.

Front Biosci. 2009 Jun 1;14:5239-59. Review.PMID: 19482613 [PubMed - indexed for MEDLINE]Related articles

Sonic hedgehog expands diaphyseal trabecular bone altering bone marrow niche and lymphocyte compartment.

Kiuru M, Hidaka C, Hubner RH, Solomon J, Krause A, Leopold PL, Crystal RG.

Mol Ther. 2009 Aug;17(8):1442-52. Epub 2009 May 12.PMID: 19436267 [PubMed - indexed for MEDLINE]Related articles

Health checks every five years. Ankle brachial pressure index?

Chong P, Gerrard D, Leopold P.

BMJ. 2009 Apr 21;338:b1599. doi: 10.1136/bmj.b1599. No abstract available. PMID: 19383739 [PubMed - indexed for MEDLINE]Related articles

A new central venous catheter cap: decreased microbial growth and risk for catheter-related bloodstream infection.

Buchman AL, Spapperi J, Leopold P.

J Vasc Access. 2009 Jan-Mar;10(1):11-21.PMID: 19340794 [PubMed - indexed for MEDLINE]Related articles

Medical device development: design, engineering, testing, and legal issues protection-steps in the process to success.

Buchman AL, Spapperi J, Francuzenko KW, Blakeslee MR, Toffenetti J, Leopold P; FDA Related Matters Committee of the American College of Gastroenterology.

Am J Gastroenterol. 2009 Mar;104(3):543-5. No abstract available. PMID: 19262512 [PubMed - indexed for MEDLINE]Related articles

Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.

Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG.

Hum Gene Ther. 2009 Mar;20(3):267-81.PMID: 19257851 [PubMed - indexed for MEDLINE]Related articles

Functional CFTR Expression in Cystic Fibrosis Airway Epithelial Cells by AAV6.2-mediated Segmental Trans-splicing.

Song Y, Lou H, Boyer J, Limberis M, Vandenberghe L, Hackett N, Leopold P, Wilson J, Crystal R.

Hum Gene Ther. 2008 Dec 12. [Epub ahead of print]PMID: 19072293 [PubMed - as supplied by publisher]Related articles

The TOR pathway couples nutrition and developmental timing in Drosophila.

Layalle S, Arquier N, Léopold P.

Dev Cell. 2008 Oct;15(4):568-77.PMID: 18854141 [PubMed - indexed for MEDLINE]Related articles

Dysfunctional glycogen storage in a mouse model of alpha1-antitrypsin deficiency.

Hubner RH, Leopold PL, Kiuru M, De BP, Krause A, Crystal RG.

Am J Respir Cell Mol Biol. 2009 Feb;40(2):239-47. Epub 2008 Aug 7.PMID: 18688041 [PubMed - indexed for MEDLINE]Related articles

Drosophila ALS regulates growth and metabolism through functional interaction with insulin-like peptides.

Arquier N, Géminard C, Bourouis M, Jarretou G, Honegger B, Paix A, Léopold P.

Cell Metab. 2008 Apr;7(4):333-8. Erratum in: Cell Metab. 2008 Nov;8(5):446. PMID: 18396139 [PubMed - indexed for MEDLINE]Related articles

Drosophila and the genetics of the internal milieu.

Leopold P, Perrimon N.

Nature. 2007 Nov 8;450(7167):186-8. Review.PMID: 17994083 [PubMed - indexed for MEDLINE]Related articles

Intracellular trafficking of adenovirus: many means to many ends.

Leopold PL, Crystal RG.

Adv Drug Deliv Rev. 2007 Aug 10;59(8):810-21. Epub 2007 Jun 28. Review.PMID: 17707546 [PubMed - indexed for MEDLINE]Related articles

Human embryonic stem cells and gene therapy.

Strulovici Y, Leopold PL, O'Connor TP, Pergolizzi RG, Crystal RG.

Mol Ther. 2007 May;15(5):850-66. Epub 2007 Mar 20. Review.PMID: 17356540 [PubMed - indexed for MEDLINE]Related articles

Fly foie gras: modeling fatty liver in Drosophila.

Arquier N, Léopold P.

Cell Metab. 2007 Feb;5(2):83-5.PMID: 17276349 [PubMed - indexed for MEDLINE]Related articles

Responses of the human airway epithelium transcriptome to in vivo injury.

Heguy A, Harvey BG, Leopold PL, Dolgalev I, Raman T, Crystal RG.

Physiol Genomics. 2007 Apr 24;29(2):139-48. Epub 2006 Dec 12.PMID: 17164391 [PubMed - indexed for MEDLINE]Related articlesFree article

Modification of gene expression of the small airway epithelium in response to cigarette smoking.

Harvey BG, Heguy A, Leopold PL, Carolan BJ, Ferris B, Crystal RG.

J Mol Med. 2007 Jan;85(1):39-53. Epub 2006 Nov 8. Erratum in: J Mol Med. 2008 Jul;86(7):853. PMID: 17115125 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers.

Carolan BJ, Heguy A, Harvey BG, Leopold PL, Ferris B, Crystal RG.

Cancer Res. 2006 Nov 15;66(22):10729-40.PMID: 17108109 [PubMed - indexed for MEDLINE]Related articlesFree article

Neutralized adenovirus-immune complexes can mediate effective gene transfer via an Fc receptor-dependent infection pathway.

Leopold PL, Wendland RL, Vincent T, Crystal RG.

J Virol. 2006 Oct;80(20):10237-47.PMID: 17005701 [PubMed - indexed for MEDLINE]Related articlesFree article

A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes.

Kelkar S, De BP, Gao G, Wilson JM, Crystal RG, Leopold PL.

J Virol. 2006 Aug;80(15):7781-5.PMID: 16840360 [PubMed - indexed for MEDLINE]Related articlesFree article

Development biology. Linking nutrition and tissue growth.

Léopold P, Layalle S.

Science. 2006 Jun 2;312(5778):1317-8. No abstract available. PMID: 16741099 [PubMed - indexed for MEDLINE]Related articles

Viral strategies for intracellular trafficking: motors and microtubules.

Leopold PL, Pfister KK.

Traffic. 2006 May;7(5):516-23. Review.PMID: 16643275 [PubMed - indexed for MEDLINE]Related articles

Correction of a murine model of von Willebrand disease by gene transfer.

Pergolizzi RG, Jin G, Chan D, Pierre L, Bussel J, Ferris B, Leopold PL, Crystal RG.

Blood. 2006 Aug 1;108(3):862-9. Epub 2006 Apr 25.PMID: 16638935 [PubMed - indexed for MEDLINE]Related articlesFree article

[Steroids, insulin and growth: the flies dope the research]

Colombani J, Bianchini L, Layalle S, Léopold P.

Med Sci (Paris). 2006 Mar;22(3):241-3. French. No abstract available. PMID: 16527200 [PubMed - indexed for MEDLINE]Related articles

High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses.

De BP, Heguy A, Hackett NR, Ferris B, Leopold PL, Lee J, Pierre L, Gao G, Wilson JM, Crystal RG.

Mol Ther. 2006 Jan;13(1):67-76. Epub 2005 Nov 2.PMID: 16260185 [PubMed - indexed for MEDLINE]Related articles

Antagonistic actions of ecdysone and insulins determine final size in Drosophila.

Colombani J, Bianchini L, Layalle S, Pondeville E, Dauphin-Villemant C, Antoniewski C, Carré C, Noselli S, Léopold P.

Science. 2005 Oct 28;310(5748):667-70. Epub 2005 Sep 22.PMID: 16179433 [PubMed - indexed for MEDLINE]Related articlesFree article

AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.

Sondhi D, Peterson DA, Giannaris EL, Sanders CT, Mendez BS, De B, Rostkowski AB, Blanchard B, Bjugstad K, Sladek JR Jr, Redmond DE Jr, Leopold PL, Kaminsky SM, Hackett NR, Crystal RG.

Gene Ther. 2005 Nov;12(22):1618-32.PMID: 16052206 [PubMed - indexed for MEDLINE]Related articles

Enhanced efficacy of cholesterol-minus sonic hedgehog in postnatal skin.

Lou H, Crystal RG, Leopold PL.

Mol Ther. 2005 Sep;12(3):575-8.PMID: 15987672 [PubMed - indexed for MEDLINE]Related articles

Drosophila Lk6 kinase controls phosphorylation of eukaryotic translation initiation factor 4E and promotes normal growth and development.

Arquier N, Bourouis M, Colombani J, Léopold P.

Curr Biol. 2005 Jan 11;15(1):19-23.PMID: 15649359 [PubMed - indexed for MEDLINE]Related articles

Mass mapping of cancer cell lysates using two-dimensional liquid separations, electrospray-time of flight-mass spectrometry, and automated data processing.

Buchanan NS, Hamler RL, Leopold PE, Miller FR, Lubman DM.

Electrophoresis. 2005 Jan;26(1):248-56.PMID: 15624161 [PubMed - indexed for MEDLINE]Related articles

Intrapleural administration of a serotype 5 adeno-associated virus coding for alpha1-antitrypsin mediates persistent, high lung and serum levels of alpha1-antitrypsin.

De B, Heguy A, Leopold PL, Wasif N, Korst RJ, Hackett NR, Crystal RG.

Mol Ther. 2004 Dec;10(6):1003-10.PMID: 15564132 [PubMed - indexed for MEDLINE]Related articles

Neuronal differentiation: TOR and insulin receptor pathways set the tempo.

Léopold P.

Cell. 2004 Oct 1;119(1):4-5. Review.PMID: 15454075 [PubMed - indexed for MEDLINE]Related articles

Cytoplasmic dynein mediates adenovirus binding to microtubules.

Kelkar SA, Pfister KK, Crystal RG, Leopold PL.

J Virol. 2004 Sep;78(18):10122-32.PMID: 15331745 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells.

Vincent T, Pettersson RF, Crystal RG, Leopold PL.

J Virol. 2004 Aug;78(15):8047-58.PMID: 15254176 [PubMed - indexed for MEDLINE]Related articlesFree article

[A nutrient sensor mechanism]

Colombani J, Arquier N, Léopold P.

Med Sci (Paris). 2004 Feb;20(2):141-3. French. No abstract available. PMID: 14997429 [PubMed - indexed for MEDLINE]Related articlesFree article

Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses.

Worgall S, Busch A, Rivara M, Bonnyay D, Leopold PL, Merritt R, Hackett NR, Rovelink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG.

J Virol. 2004 Mar;78(5):2572-80.PMID: 14963160 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs.

Whitlock PR, Hackett NR, Leopold PL, Rosengart TK, Crystal RG.

Mol Ther. 2004 Jan;9(1):67-75.PMID: 14741779 [PubMed - indexed for MEDLINE]Related articles

Association of adenovirus with the microtubule organizing center.

Bailey CJ, Crystal RG, Leopold PL.

J Virol. 2003 Dec;77(24):13275-87.PMID: 14645584 [PubMed - indexed for MEDLINE]Related articlesFree article

The lateral accessory saphenous vein - a common cause of recurrent varicose veins.

Garner JP, Heppell PS, Leopold PW.

Ann R Coll Surg Engl. 2003 Nov;85(6):389-92.PMID: 14629879 [PubMed - indexed for MEDLINE]Related articlesFree article

A nutrient sensor mechanism controls Drosophila growth.

Colombani J, Raisin S, Pantalacci S, Radimerski T, Montagne J, Léopold P.

Cell. 2003 Sep 19;114(6):739-49.PMID: 14505573 [PubMed - indexed for MEDLINE]Related articles

The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

Pantalacci S, Tapon N, Léopold P.

Nat Cell Biol. 2003 Oct;5(10):921-7. Epub 2003 Sep 21.PMID: 14502295 [PubMed - indexed for MEDLINE]Related articles

A new genetic locus controlling growth and proliferation in Drosophila melanogaster.

Raisin S, Pantalacci S, Breittmayer JP, Léopold P.

Genetics. 2003 Jul;164(3):1015-25.PMID: 12871911 [PubMed - indexed for MEDLINE]Related articlesFree article

[Drosophila and cancer: proof by sav]

Pantalacci S, Léopold P, Tapon N.

Med Sci (Paris). 2003 Feb;19(2):149-51. French. No abstract available. PMID: 12836609 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell physiology as a variable in gene transfer to endothelium.

Leopold PL.

Curr Atheroscler Rep. 2003 May;5(3):171-7. Review.PMID: 12667428 [PubMed - indexed for MEDLINE]Related articles

Multicentre Aneurysm Screening Study (MASS).

Tomlinson M, Arshad I, Gerrard D, Leopold P.

Lancet. 2003 Mar 22;361(9362):1057; author reply 1058. No abstract available. PMID: 12660084 [PubMed - indexed for MEDLINE]Related articles

Automated postprocessing of electrospray LC/MS data for profiling protein expression in bacteria.

Williams TL, Leopold P, Musser S.

Anal Chem. 2002 Nov 15;74(22):5807-13.PMID: 12463365 [PubMed - indexed for MEDLINE]Related articles

Drosophila crooked-neck protein co-fractionates in a multiprotein complex with splicing factors.

Raisin-Tani S, Léopold P.

Biochem Biophys Res Commun. 2002 Aug 16;296(2):288-92.PMID: 12163015 [PubMed - indexed for MEDLINE]Related articles

In vivo enhanced expression of patched dampens the sonic hedgehog pathway.

Bergstein I, Leopold PL, Sato N, Panteleyev A, Christiano A, Crystal R.

Mol Ther. 2002 Aug;6(2):258-64.PMID: 12161193 [PubMed - indexed for MEDLINE]Related articles

Inhibition of HIV-1 replication in alveolar macrophages by adenovirus gene transfer vectors.

Rice J, Connor R, Worgall S, Moore JP, Leopold PL, Kaner RJ, Crystal RG.

Am J Respir Cell Mol Biol. 2002 Aug;27(2):214-9.PMID: 12151313 [PubMed - indexed for MEDLINE]Related articlesFree article