PubMed

High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.

Masson E, Koren S, Razik F, Goldberg H, Kwan EP, Sheu L, Gaisano HY, Fantus IG.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1251-61. Epub 2009 Feb 17.PMID: 19223654 [PubMed - indexed for MEDLINE]Related articles

Rescuing the subprime meltdown in insulin exocytosis in diabetes.

Kwan EP, Gaisano HY.

Ann N Y Acad Sci. 2009 Jan;1152:154-64. Review.PMID: 19161386 [PubMed - indexed for MEDLINE]Related articles

The RalA GTPase is a central regulator of insulin exocytosis from pancreatic islet beta cells.

Lopez JA, Kwan EP, Xie L, He Y, James DE, Gaisano HY.

J Biol Chem. 2008 Jun 27;283(26):17939-45. Epub 2008 Apr 21.PMID: 18426794 [PubMed - indexed for MEDLINE]Related articlesFree article

New insights into the molecular mechanisms of priming of insulin exocytosis.

Kwan EP, Gaisano HY.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:99-108.PMID: 17919184 [PubMed - indexed for MEDLINE]Related articles

Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet beta cells.

Kwan EP, Gao X, Leung YM, Gaisano HY.

Pancreas. 2007 Oct;35(3):e45-54.PMID: 17895835 [PubMed - indexed for MEDLINE]Related articles

SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins.

Leung YM, Kwan EP, Ng B, Kang Y, Gaisano HY.

Endocr Rev. 2007 Oct;28(6):653-63. Epub 2007 Sep 18. Review.PMID: 17878408 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.

Kwan EP, Xie L, Sheu L, Ohtsuka T, Gaisano HY.

Diabetes. 2007 Oct;56(10):2579-88. Epub 2007 Jul 16.PMID: 17639022 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance.

Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY.

Diabetes. 2006 May;55(5):1421-9.PMID: 16644700 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells.

Kwan EP, Gaisano HY.

Diabetes. 2005 Sep;54(9):2734-43.PMID: 16123364 [PubMed - indexed for MEDLINE]Related articlesFree article