PubMed

The roles of telomeres and telomerase in beta-cell regeneration.

Liew CW, Holman A, Kulkarni RN.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:21-9.PMID: 19817785 [PubMed - in process]Related articles

Mouse-specific tandem IgY7-SuperMix immunoaffinity separations for improved LC-MS/MS coverage of the plasma proteome.

Zhou JY, Petritis BO, Petritis K, Norbeck AD, Weitz KK, Moore RJ, Camp DG, Kulkarni RN, Smith RD, Qian WJ.

J Proteome Res. 2009 Nov;8(11):5387-95.PMID: 19722698 [PubMed - in process]Related articles

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction.

Borowiec M, Liew CW, Thompson R, Boonyasrisawat W, Hu J, Mlynarski WM, El Khattabi I, Kim SH, Marselli L, Rich SS, Krolewski AS, Bonner-Weir S, Sharma A, Sale M, Mychaleckyj JC, Kulkarni RN, Doria A.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14460-5. Epub 2009 Aug 10.PMID: 19667185 [PubMed - indexed for MEDLINE]Related articles

Uncoupling modifier genes from uncoupling protein 2 in pancreatic beta-cells.

Kulkarni RN.

Endocrinology. 2009 Jul;150(7):2994-6. No abstract available. PMID: 19549885 [PubMed - indexed for MEDLINE]Related articles

Insulin signaling in alpha cells modulates glucagon secretion in vivo.

Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN.

Cell Metab. 2009 Apr;9(4):350-61.PMID: 19356716 [PubMed - indexed for MEDLINE]Related articles

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Assmann A, Ueki K, Winnay JN, Kadowaki T, Kulkarni RN.

Mol Cell Biol. 2009 Jun;29(11):3219-28. Epub 2009 Mar 9.PMID: 19273608 [PubMed - indexed for MEDLINE]Related articles

Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.

Torii S, Saito N, Kawano A, Hou N, Ueki K, Kulkarni RN, Takeuchi T.

Diabetes. 2009 Mar;58(3):682-92. Epub 2008 Dec 10.PMID: 19073770 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells.

Hisanaga E, Nagasawa M, Ueki K, Kulkarni RN, Mori M, Kojima I.

Diabetes. 2009 Jan;58(1):174-84. Epub 2008 Nov 4.PMID: 18984736 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt signaling: relevance to beta-cell biology and diabetes.

Welters HJ, Kulkarni RN.

Trends Endocrinol Metab. 2008 Dec;19(10):349-55. Epub 2008 Oct 14. Review.PMID: 18926717 [PubMed - indexed for MEDLINE]Related articles

Differential expression of cell cycle proteins during ageing of pancreatic islet cells.

Hinault C, Hu J, Maier BF, Mirmira RG, Kulkarni RN.

Diabetes Obes Metab. 2008 Nov;10 Suppl 4:136-46. Review.PMID: 18834441 [PubMed - indexed for MEDLINE]Related articles

Growth factor control of pancreatic islet regeneration and function.

Assmann A, Hinault C, Kulkarni RN.

Pediatr Diabetes. 2009 Feb;10(1):14-32. Epub 2008 Sep 19. Review. No abstract available. PMID: 18828795 [PubMed - indexed for MEDLINE]Related articles

Retraction. Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis.

Wang L, Huang J, Saha P, Kulkarni RN, Hu M, Kim Y, Park K, Chan L, Rajan AS, Lee I, Moore DD.

Mol Endocrinol. 2008 Sep;22(9):2203. No abstract available. PMID: 18757780 [PubMed - indexed for MEDLINE]Related articlesFree article

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.

Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR.

Nature. 2008 Aug 21;454(7207):1000-4.PMID: 18719589 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the mouse pancreatic islet proteome and comparative analysis with other mouse tissues.

Petyuk VA, Qian WJ, Hinault C, Gritsenko MA, Singhal M, Monroe ME, Camp DG 2nd, Kulkarni RN, Smith RD.

J Proteome Res. 2008 Aug;7(8):3114-26. Epub 2008 Jun 21.PMID: 18570455 [PubMed - indexed for MEDLINE]Related articlesFree article

Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

DeAngelis AM, Heinrich G, Dai T, Bowman TA, Patel PR, Lee SJ, Hong EG, Jung DY, Assmann A, Kulkarni RN, Kim JK, Najjar SM.

Diabetes. 2008 Sep;57(9):2296-303. Epub 2008 Jun 10.PMID: 18544705 [PubMed - indexed for MEDLINE]Related articlesFree article

Inheritance of pollen-less anthers and "thrum" and "pin" flowers in periwinkle.

Kulkarni RN, Baskaran K.

J Hered. 2008 Jul-Aug;99(4):426-31. Epub 2008 Mar 13.PMID: 18339651 [PubMed - indexed for MEDLINE]Related articlesFree article

A patient with type B insulin resistance syndrome, responsive to immune therapy.

Page KA, Dejardin S, Kahn CR, Kulkarni RN, Herold KC, Inzucchi SE.

Nat Clin Pract Endocrinol Metab. 2007 Dec;3(12):835-40.PMID: 18026162 [PubMed - indexed for MEDLINE]Related articles

Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.

Handschin C, Choi CS, Chin S, Kim S, Kawamori D, Kurpad AJ, Neubauer N, Hu J, Mootha VK, Kim YB, Kulkarni RN, Shulman GI, Spiegelman BM.

J Clin Invest. 2007 Nov;117(11):3463-74.PMID: 17932564 [PubMed - indexed for MEDLINE]Related articlesFree article

Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.

Morioka T, Asilmaz E, Hu J, Dishinger JF, Kurpad AJ, Elias CF, Li H, Elmquist JK, Kennedy RT, Kulkarni RN.

J Clin Invest. 2007 Oct;117(10):2860-8.PMID: 17909627 [PubMed - indexed for MEDLINE]Related articlesFree article

Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.

Matsumura K, Chang BH, Fujimiya M, Chen W, Kulkarni RN, Eguchi Y, Kimura H, Kojima H, Chan L.

Mol Cell Biol. 2007 Sep;27(17):6026-37. Epub 2007 Jun 18. Erratum in: Mol Cell Biol. 2007 Oct;27(20):7354. PMID: 17576812 [PubMed - indexed for MEDLINE]Related articlesFree article

Ephs and ephrins keep pancreatic Beta cells connected.

Kulkarni RN, Kahn CR.

Cell. 2007 Apr 20;129(2):241-3.PMID: 17448984 [PubMed - indexed for MEDLINE]Related articles

Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance.

Okada T, Liew CW, Hu J, Hinault C, Michael MD, Krtzfeldt J, Yin C, Holzenberger M, Stoffel M, Kulkarni RN.

Proc Natl Acad Sci U S A. 2007 May 22;104(21):8977-82. Epub 2007 Apr 6.PMID: 17416680 [PubMed - indexed for MEDLINE]Related articlesFree article

Microsurgical anatomy of the posterior circulation.

Pai BS, Varma RG, Kulkarni RN, Nirmala S, Manjunath LC, Rakshith S.

Neurol India. 2007 Jan-Mar;55(1):31-41.PMID: 17272897 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanin concentrating hormone is a novel regulator of islet function and growth.

Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN.

Diabetes. 2007 Feb;56(2):311-9.PMID: 17259374 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3.

Koh HJ, Arnolds DE, Fujii N, Tran TT, Rogers MJ, Jessen N, Li Y, Liew CW, Ho RC, Hirshman MF, Kulkarni RN, Kahn CR, Goodyear LJ.

Mol Cell Biol. 2006 Nov;26(22):8217-27. Epub 2006 Sep 11.PMID: 16966378 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular approaches to study control of glucose homeostasis.

Neubauer N, Kulkarni RN.

ILAR J. 2006;47(3):199-211. Review.PMID: 16804195 [PubMed - indexed for MEDLINE]Related articlesFree article

Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis.

Wang L, Huang J, Saha P, Kulkarni RN, Hu M, Kim Y, Park K, Chan L, Rajan AS, Lee I, Moore DD.

Mol Endocrinol. 2006 Nov;20(11):2671-81. Epub 2006 Jun 27. Retraction in: Wang L, Huang J, Saha P, Kulkarni RN, Hu M, Kim Y, Park K, Chan L, Rajan AS, Lee I, Moore DD. Mol Endocrinol. 2008 Sep;22(9):2203. PMID: 16803864 [PubMed - indexed for MEDLINE]Related articlesFree article

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M.

Science. 2006 Jun 23;312(5781):1763-6.PMID: 16794074 [PubMed - indexed for MEDLINE]Related articlesFree article

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.

Ueki K, Okada T, Hu J, Liew CW, Assmann A, Dahlgren GM, Peters JL, Shackman JG, Zhang M, Artner I, Satin LS, Stein R, Holzenberger M, Kennedy RT, Kahn CR, Kulkarni RN.

Nat Genet. 2006 May;38(5):583-8. Epub 2006 Apr 23.PMID: 16642022 [PubMed - indexed for MEDLINE]Related articles

A study of leucorrhoea in reproductive age group women of Nagpur City.

Kulkarni RN, Durge PM.

Indian J Public Health. 2005 Oct-Dec;49(4):238-9.PMID: 16479906 [PubMed - indexed for MEDLINE]Related articles

Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia.

He Z, Opland DM, Way KJ, Ueki K, Bodyak N, Kang PM, Izumo S, Kulkarni RN, Wang B, Liao R, Kahn CR, King GL.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):787-93. Epub 2006 Feb 9.PMID: 16469952 [PubMed - indexed for MEDLINE]Related articlesFree article

New insights into the roles of insulin/IGF-I in the development and maintenance of beta-cell mass.

Kulkarni RN.

Rev Endocr Metab Disord. 2005 Aug;6(3):199-210. Review. No abstract available. PMID: 16151624 [PubMed - indexed for MEDLINE]Related articles

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.

Gunton JE, Kulkarni RN, Yim S, Okada T, Hawthorne WJ, Tseng YH, Roberson RS, Ricordi C, O'Connell PJ, Gonzalez FJ, Kahn CR.

Cell. 2005 Aug 12;122(3):337-49.PMID: 16096055 [PubMed - indexed for MEDLINE]Related articles

Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis.

Bates SH, Kulkarni RN, Seifert M, Myers MG Jr.

Cell Metab. 2005 Mar;1(3):169-78.PMID: 16054060 [PubMed - indexed for MEDLINE]Related articles

Microsurgical anatomy of the middle cerebral artery.

Pai SB, Varma RG, Kulkarni RN.

Neurol India. 2005 Jun;53(2):186-90.PMID: 16010057 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.

Hennige AM, Ozcan U, Okada T, Jhala US, Schubert M, White MF, Kulkarni RN.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E337-46. Epub 2005 Apr 12.PMID: 15827066 [PubMed - indexed for MEDLINE]Related articlesFree article

Allelic differences at two loci govern different mechanisms of intraflower self-pollination in self-pollinating strains of periwinkle.

Kulkarni RN, Sreevalli Y, Baskaran K.

J Hered. 2005 Jan-Feb;96(1):71-7. Epub 2004 Dec 14.PMID: 15598715 [PubMed - indexed for MEDLINE]Related articlesFree article

PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance.

Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR.

J Clin Invest. 2004 Sep;114(6):828-36.PMID: 15372107 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3.

Kulkarni RN, Roper MG, Dahlgren G, Shih DQ, Kauri LM, Peters JL, Stoffel M, Kennedy RT.

Diabetes. 2004 Jun;53(6):1517-25.PMID: 15161756 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.

Goren HJ, Kulkarni RN, Kahn CR.

Endocrinology. 2004 Jul;145(7):3307-23. Epub 2004 Mar 24.PMID: 15044376 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular biology. HNFs--linking the liver and pancreatic islets in diabetes.

Kulkarni RN, Kahn CR.

Science. 2004 Feb 27;303(5662):1311-2. No abstract available. PMID: 14988544 [PubMed - indexed for MEDLINE]Related articles

The islet beta-cell.

Kulkarni RN.

Int J Biochem Cell Biol. 2004 Mar;36(3):365-71. Review.PMID: 14687913 [PubMed - indexed for MEDLINE]Related articles

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.

Hennige AM, Burks DJ, Ozcan U, Kulkarni RN, Ye J, Park S, Schubert M, Fisher TL, Dow MA, Leshan R, Zakaria M, Mossa-Basha M, White MF.

J Clin Invest. 2003 Nov;112(10):1521-32.PMID: 14617753 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice.

Otani K, Kulkarni RN, Baldwin AC, Krutzfeldt J, Ueki K, Stoffel M, Kahn CR, Polonsky KS.

Am J Physiol Endocrinol Metab. 2004 Jan;286(1):E41-9. Epub 2003 Sep 30.PMID: 14519599 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis.

Rosen ED, Kulkarni RN, Sarraf P, Ozcan U, Okada T, Hsu CH, Eisenman D, Magnuson MA, Gonzalez FJ, Kahn CR, Spiegelman BM.

Mol Cell Biol. 2003 Oct;23(20):7222-9.PMID: 14517292 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of socio-economic factors and cytology in cervical erosion in reproductive age group women.

Kulkarni RN, Durge PM.

Indian J Med Sci. 2002 Dec;56(12):598-601.PMID: 14514242 [PubMed - indexed for MEDLINE]Related articlesFree article

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M.

Genes Dev. 2003 Jul 1;17(13):1575-80.PMID: 12842910 [PubMed - indexed for MEDLINE]Related articlesFree article

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver.

Du K, Herzig S, Kulkarni RN, Montminy M.

Science. 2003 Jun 6;300(5625):1574-7.PMID: 12791994 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis.

Jiang ZY, He Z, King BL, Kuroki T, Opland DM, Suzuma K, Suzuma I, Ueki K, Kulkarni RN, Kahn CR, King GL.

J Biol Chem. 2003 Aug 22;278(34):31964-71. Epub 2003 May 29.PMID: 12775712 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance.

Almind K, Kulkarni RN, Lannon SM, Kahn CR.

Diabetes. 2003 Jun;52(6):1535-43.PMID: 12765967 [PubMed - indexed for MEDLINE]Related articlesFree article