PubMed

Quantitative PCR Analysis for Bcl-2/IgH in a Phase III Study of Yttrium-90 Ibritumomab Tiuxetan As Consolidation of First Remission in Patients With Follicular Lymphoma.

Goff L, Summers K, Iqbal S, Kuhlmann J, Kunz M, Louton T, Hagenbeek A, Morschhauser F, Putz B, Lister A, Rohatiner A.

J Clin Oncol. 2009 Oct 26. [Epub ahead of print]PMID: 19858392 [PubMed - as supplied by publisher]Related articles

Dosimetry of 90Y-ibritumomab tiuxetan as consolidation of first remission in advanced-stage follicular lymphoma: results from the international phase 3 first-line indolent trial.

Delaloye AB, Antonescu C, Louton T, Kuhlmann J, Hagenbeek A.

J Nucl Med. 2009 Nov;50(11):1837-43. Epub 2009 Oct 16.PMID: 19837764 [PubMed - in process]Related articles

Farnesylation of pex19p is required for its structural integrity and function in peroxisome biogenesis.

Rucktäschel R, Thoms S, Sidorovitch V, Halbach A, Pechlivanis M, Volkmer R, Alexandrov K, Kuhlmann J, Rottensteiner H, Erdmann R.

J Biol Chem. 2009 Jul 31;284(31):20885-96. Epub 2009 May 18.PMID: 19451657 [PubMed - indexed for MEDLINE]Related articles

Analysis of heme-reconstitution of apoenzymes by means of surface plasmon resonance.

Fruk L, Kuhlmann J, Niemeyer CM.

Chem Commun (Camb). 2009 Jan 8;(2):230-2. Epub 2008 Dec 1.PMID: 19099078 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetics of alemtuzumab and the relevance in clinical practice.

Elter T, Molnar I, Kuhlmann J, Hallek M, Wendtner C.

Leuk Lymphoma. 2008 Dec;49(12):2256-62. Review.PMID: 19052972 [PubMed - indexed for MEDLINE]Related articles

Secondary structure of lipidated Ras bound to a lipid bilayer.

Güldenhaupt J, Adigüzel Y, Kuhlmann J, Waldmann H, Kötting C, Gerwert K.

FEBS J. 2008 Dec;275(23):5910-8.PMID: 19021766 [PubMed - indexed for MEDLINE]Related articles

Applicability of superfolder YFP bimolecular fluorescence complementation in vitro.

Ottmann C, Weyand M, Wolf A, Kuhlmann J, Ottmann C.

Biol Chem. 2009 Jan;390(1):81-90.PMID: 19007309 [PubMed - indexed for MEDLINE]Related articles

Synergism of aromatic amines and benzo[a]pyrene in induction of Ah receptor-dependent genes.

Borza A, Plöttner S, Wolf A, Behm C, Selinski S, Hengstler JG, Roos PH, Bolt HM, Kuhlmann J, Föllmann W.

Arch Toxicol. 2008 Dec;82(12):973-80. Epub 2008 Nov 7.PMID: 18989657 [PubMed - indexed for MEDLINE]Related articles

Phase III trial of consolidation therapy with yttrium-90-ibritumomab tiuxetan compared with no additional therapy after first remission in advanced follicular lymphoma.

Morschhauser F, Radford J, Van Hoof A, Vitolo U, Soubeyran P, Tilly H, Huijgens PC, Kolstad A, d'Amore F, Gonzalez Diaz M, Petrini M, Sebban C, Zinzani PL, van Oers MH, van Putten W, Bischof-Delaloye A, Rohatiner A, Salles G, Kuhlmann J, Hagenbeek A.

J Clin Oncol. 2008 Nov 10;26(32):5156-64. Epub 2008 Oct 14.PMID: 18854568 [PubMed - indexed for MEDLINE]Related articles

Mapping the isoprenoid binding pocket of PDEdelta by a semisynthetic, photoactivatable N-Ras lipoprotein.

Alexander M, Gerauer M, Pechlivanis M, Popkirova B, Dvorsky R, Brunsveld L, Waldmann H, Kuhlmann J.

Chembiochem. 2009 Jan 5;10(1):98-108.PMID: 18846587 [PubMed - indexed for MEDLINE]Related articles

[Hands and feet of prosimians primates. Attempts of morphologic characterization]

Kuhlmann JN.

Morphologie. 2008 Aug;92(297):68-77. Epub 2008 Sep 23. French. PMID: 18815065 [PubMed - indexed for MEDLINE]Related articles

[The first ray of the hand and the foot in the primates (II). Functional anatomy]

Kuhlmann JN.

Morphologie. 2008 Aug;92(297):55-67. French. PMID: 18675573 [PubMed - indexed for MEDLINE]Related articles

The applications of biomarkers in early clinical drug development to improve decision-making processes.

Kuhlmann J, Wensing G.

Curr Clin Pharmacol. 2006 May;1(2):185-91. Review.PMID: 18666370 [PubMed - indexed for MEDLINE]Related articles

Synthesis and application of fluorescence-labeled Ras-proteins for live-cell imaging.

Reents R, Wagner M, Kuhlmann J, Waldmann H.

Angew Chem Int Ed Engl. 2004 May 10;43(20):2711-4. No abstract available. PMID: 18629997 [PubMed - indexed for MEDLINE]Related articles

Evaluation of time dependence and interindividual differences in benzo[a]pyrene-mediated CYP1A1 induction and genotoxicity in porcine urinary bladder cell cultures.

Plottner S, Borza A, Wolf A, Bolt HM, Kuhlmann J, Follmann W.

J Toxicol Environ Health A. 2008;71(13-14):969-75.PMID: 18569604 [PubMed - indexed for MEDLINE]Related articles

Miniaturization of primary porcine urinary bladder epithelial cell cultures and application for gene expression studies after exposure to benzo[a]pyrene.

Alexander M, Behm C, Follmann W, Kuhlmann J.

J Toxicol Environ Health A. 2008;71(13-14):915-22.PMID: 18569596 [PubMed - indexed for MEDLINE]Related articles

Photochemical surface patterning by the thiol-ene reaction.

Jonkheijm P, Weinrich D, Köhn M, Engelkamp H, Christianen PC, Kuhlmann J, Maan JC, Nüsse D, Schroeder H, Wacker R, Breinbauer R, Niemeyer CM, Waldmann H.

Angew Chem Int Ed Engl. 2008;47(23):4421-4. No abstract available. PMID: 18428169 [PubMed - indexed for MEDLINE]Related articles

Mapping of phosphorylation-dependent anti-tau monoclonal antibodies in immunoblots using human tau-constructs synthesized by native chemical ligation.

Singer D, Herth N, Kuhlmann J, Holland-Nell K, Beck-Sickinger AG, Hoffmann R.

Biochem Biophys Res Commun. 2008 Mar 7;367(2):318-22. Epub 2007 Dec 26.PMID: 18162172 [PubMed - indexed for MEDLINE]Related articles

B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding.

Fischer A, Hekman M, Kuhlmann J, Rubio I, Wiese S, Rapp UR.

J Biol Chem. 2007 Sep 7;282(36):26503-16. Epub 2007 Jul 16.PMID: 17635919 [PubMed - indexed for MEDLINE]Related articlesFree article

CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats.

Herling AW, Gossel M, Haschke G, Stengelin S, Kuhlmann J, Müller G, Schmoll D, Kramer W.

Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E826-32. Epub 2007 Jun 26.PMID: 17595216 [PubMed - indexed for MEDLINE]Related articlesFree article

Population pharmacokinetics-pharmacodynamics of alemtuzumab (Campath) in patients with chronic lymphocytic leukaemia and its link to treatment response.

Mould DR, Baumann A, Kuhlmann J, Keating MJ, Weitman S, Hillmen P, Brettman LR, Reif S, Bonate PL.

Br J Clin Pharmacol. 2007 Sep;64(3):278-91. Epub 2007 May 16.PMID: 17506867 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenylation of Ras facilitates hSOS1-promoted nucleotide exchange, upon Ras binding to the regulatory site.

Pechlivanis M, Ringel R, Popkirova B, Kuhlmann J.

Biochemistry. 2007 May 8;46(18):5341-8. Epub 2007 Apr 17.PMID: 17437339 [PubMed - indexed for MEDLINE]Related articles

Structural and biochemical characterization of the Importin-beta.Ran.GTP.RanBD1 complex.

Sarić M, Zhao X, Körner C, Nowak C, Kuhlmann J, Vetter IR.

FEBS Lett. 2007 Apr 3;581(7):1369-76. Epub 2007 Mar 6.PMID: 17359978 [PubMed - indexed for MEDLINE]Related articles

Pharmacodynamic Effects of an Angiotensin II Receptor-Antagonist in Phase I-Comparison between Healthy Subjects and Patients with Hypertension.

Wensing G, Ochmann K, Boettcher M, Schäfer A, Kuhlmann J.

Biomark Insights. 2007 Mar 22;2:81-93.PMID: 19662194 [PubMed - in process]Related articlesFree article

Membrane binding of a lipidated N-Ras protein studied in lipid monolayers.

Bringezu F, Majerowicz M, Wen S, Reuther G, Tan KT, Kuhlmann J, Waldmann H, Huster D.

Eur Biophys J. 2007 Apr;36(4-5):491-8. Epub 2006 Dec 22.PMID: 17186235 [PubMed - indexed for MEDLINE]Related articles

The applications of biomarkers in early clinical drug development to improve decision-making processes.

Kuhlmann J.

Ernst Schering Res Found Workshop. 2007;(59):29-45. Review.PMID: 17117713 [PubMed - indexed for MEDLINE]Related articles

Hydrophobic modifications of Ras proteins by isoprenoid groups and fatty acids--More than just membrane anchoring.

Pechlivanis M, Kuhlmann J.

Biochim Biophys Acta. 2006 Dec;1764(12):1914-31. Epub 2006 Oct 4. Review.PMID: 17110180 [PubMed - indexed for MEDLINE]Related articles

The lipidated membrane anchor of full length N-Ras protein shows an extensive dynamics as revealed by solid-state NMR spectroscopy.

Reuther G, Tan KT, Vogel A, Nowak C, Arnold K, Kuhlmann J, Waldmann H, Huster D.

J Am Chem Soc. 2006 Oct 25;128(42):13840-6.PMID: 17044712 [PubMed - indexed for MEDLINE]Related articles

Lipidated ras and rab peptides and proteins--synthesis, structure, and function.

Brunsveld L, Kuhlmann J, Alexandrov K, Wittinghofer A, Goody RS, Waldmann H.

Angew Chem Int Ed Engl. 2006 Oct 13;45(40):6622-46. Review.PMID: 17031879 [PubMed - indexed for MEDLINE]Related articles

Synthesis of palmitoylated Ras-peptides and -proteins.

Brunsveld L, Kuhlmann J, Waldmann H.

Methods. 2006 Oct;40(2):151-65. Review.PMID: 17012027 [PubMed - indexed for MEDLINE]Related articles

Light-driven water splitting for (bio-)hydrogen production: photosystem 2 as the central part of a bioelectrochemical device.

Badura A, Esper B, Ataka K, Grunwald C, Wöll C, Kuhlmann J, Heberle J, Rögner M.

Photochem Photobiol. 2006 Sep-Oct;82(5):1385-90.PMID: 16898857 [PubMed - indexed for MEDLINE]Related articles

Structural model of the membrane-bound C terminus of lipid-modified human N-ras protein.

Reuther G, Tan KT, Köhler J, Nowak C, Pampel A, Arnold K, Kuhlmann J, Waldmann H, Huster D.

Angew Chem Int Ed Engl. 2006 Aug 11;45(32):5387-90. No abstract available. PMID: 16847854 [PubMed - indexed for MEDLINE]Related articles

Insertion of lipidated Ras proteins into lipid monolayers studied by infrared reflection absorption spectroscopy (IRRAS).

Meister A, Nicolini C, Waldmann H, Kuhlmann J, Kerth A, Winter R, Blume A.

Biophys J. 2006 Aug 15;91(4):1388-401. Epub 2006 May 26.PMID: 16731561 [PubMed - indexed for MEDLINE]Related articlesFree article

A generic building block for C- and N-terminal protein-labeling and protein-immobilization.

Watzke A, Gutierrez-Rodriguez M, Köhn M, Wacker R, Schroeder H, Breinbauer R, Kuhlmann J, Alexandrov K, Niemeyer CM, Goody RS, Waldmann H.

Bioorg Med Chem. 2006 Sep 15;14(18):6288-306. Epub 2006 May 24.PMID: 16725326 [PubMed - indexed for MEDLINE]Related articles

The alpha-helix of the second chromodomain of the 43 kDa subunit of the chloroplast signal recognition particle facilitates binding to the 54 kDa subunit.

Hermkes R, Funke S, Richter C, Kuhlmann J, Schünemann D.

FEBS Lett. 2006 May 29;580(13):3107-11. Epub 2006 Apr 27.PMID: 16678173 [PubMed - indexed for MEDLINE]Related articles

Site-selective protein immobilization by Staudinger ligation.

Watzke A, Köhn M, Gutierrez-Rodriguez M, Wacker R, Schröder H, Breinbauer R, Kuhlmann J, Alexandrov K, Niemeyer CM, Goody RS, Waldmann H.

Angew Chem Int Ed Engl. 2006 Feb 20;45(9):1408-12. No abstract available. PMID: 16440394 [PubMed - indexed for MEDLINE]Related articles

Intein-mediated in vitro synthesis of lipidated Ras proteins.

Gottlieb D, Grunwald C, Nowak C, Kuhlmann J, Waldmann H.

Chem Commun (Camb). 2006 Jan 21;(3):260-2. Epub 2005 Nov 28.PMID: 16391727 [PubMed - indexed for MEDLINE]Related articlesFree article

Visualizing association of N-ras in lipid microdomains: influence of domain structure and interfacial adsorption.

Nicolini C, Baranski J, Schlummer S, Palomo J, Lumbierres-Burgues M, Kahms M, Kuhlmann J, Sanchez S, Gratton E, Waldmann H, Winter R.

J Am Chem Soc. 2006 Jan 11;128(1):192-201.PMID: 16390147 [PubMed - indexed for MEDLINE]Related articles

Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats.

Beha A, Juretschke HP, Kuhlmann J, Neumann-Haefelin C, Belz U, Gerl M, Kramer W, Roden M, Herling AW.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E989-97. Epub 2005 Dec 27.PMID: 16380389 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of serine O-glycosylation or O-phosphorylation close to the vJun nuclear localisation sequence on nuclear import.

Schlummer S, Vetter R, Kuder N, Henkel A, Chen YX, Li YM, Kuhlmann J, Waldmann H.

Chembiochem. 2006 Jan;7(1):88-97.PMID: 16345111 [PubMed - indexed for MEDLINE]Related articles

In deuterated water the unspecific adsorption of proteins is significantly slowed down: results of an SPR study using model organic surfaces.

Grunwald C, Kuhlmann J, Wöll C.

Langmuir. 2005 Sep 27;21(20):9017-9.PMID: 16171326 [PubMed - indexed for MEDLINE]Related articles

Mechanism-based pharmacokinetic-pharmacodynamic modeling-a new classification of biomarkers.

Danhof M, Alvan G, Dahl SG, Kuhlmann J, Paintaud G.

Pharm Res. 2005 Sep;22(9):1432-7. Epub 2005 Aug 24.PMID: 16132354 [PubMed - indexed for MEDLINE]Related articles

[Hands and feet of Simian primates: an attempt at morphological characterization]

Kuhlmann JN.

Morphologie. 2005 Jun;89(285):102-12. French. PMID: 16110746 [PubMed - indexed for MEDLINE]Related articles

Development and biological evaluation of acyl protein thioesterase 1 (APT1) inhibitors.

Deck P, Pendzialek D, Biel M, Wagner M, Popkirova B, Ludolph B, Kragol G, Kuhlmann J, Giannis A, Waldmann H.

Angew Chem Int Ed Engl. 2005 Aug 5;44(31):4975-80. No abstract available. PMID: 16003812 [PubMed - indexed for MEDLINE]Related articles

Concentration-effect relationships of alcohol in a computerised psychometric test system.

Versavel M, Zühlsdorf M, Unger S, Wensing G, Kuhlmann J.

Arzneimittelforschung. 2005;55(5):289-95.PMID: 15960429 [PubMed - indexed for MEDLINE]Related articles

Adverse events in volunteers participating in phase I clinical trials: a single-center five-year survey in 1,559 subjects.

Lutfullin A, Kuhlmann J, Wensing G.

Int J Clin Pharmacol Ther. 2005 May;43(5):217-26.PMID: 15906587 [PubMed - indexed for MEDLINE]Related articles

Correlation between insulin resistance and intramyocellular lipid levels in rats.

Kuhlmann J, Neumann-Haefelin C, Belz U, Kramer W, Juretschke HP, Herling AW.

Magn Reson Med. 2005 Jun;53(6):1275-82.PMID: 15906287 [PubMed - indexed for MEDLINE]Related articles

[Bilateral testicular gunshot injuries]

Kuhlmann J, Böhme H, Tauber R.

Urologe A. 2005 Aug;44(8):918-20. German. PMID: 15900433 [PubMed - indexed for MEDLINE]Related articles

Influences of caffeine, acetazolamide and cognitive stimulation on cerebral blood flow velocities.

Haase CG, Becka M, Kuhlmann J, Wensing G.

Prog Neuropsychopharmacol Biol Psychiatry. 2005 May;29(4):549-56.PMID: 15866357 [PubMed - indexed for MEDLINE]Related articles

Double-wavelength technique for surface plasmon resonance measurements: basic concept and applications for single sensors and two-dimensional sensor arrays.

Zybin A, Grunwald C, Mirsky VM, Kuhlmann J, Wolfbeis OS, Niemax K.

Anal Chem. 2005 Apr 15;77(8):2393-9.PMID: 15828772 [PubMed - indexed for MEDLINE]Related articles