PubMed

Genetic analysis of albuminuria in aging mice and concordance with loci for human diabetic nephropathy found in a genome-wide association scan.

Tsaih SW, Pezzolesi MG, Yuan R, Warram JH, Krolewski AS, Korstanje R.

Kidney Int. 2009 Nov 18. [Epub ahead of print]PMID: 19924099 [PubMed - as supplied by publisher]Related articles

In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria.

Perkins BA, Ficociello LH, Roshan B, Warram JH, Krolewski AS.

Kidney Int. 2009 Oct 21. [Epub ahead of print]PMID: 19847154 [PubMed - as supplied by publisher]Related articles

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction.

Borowiec M, Liew CW, Thompson R, Boonyasrisawat W, Hu J, Mlynarski WM, El Khattabi I, Kim SH, Marselli L, Rich SS, Krolewski AS, Bonner-Weir S, Sharma A, Sale M, Mychaleckyj JC, Kulkarni RN, Doria A.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14460-5. Epub 2009 Aug 10.PMID: 19667185 [PubMed - indexed for MEDLINE]Related articles

confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.

Pezzolesi MG, Katavetin P, Kure M, Poznik GD, Skupien J, Mychaleckyj JC, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Nov;58(11):2698-702. Epub 2009 Aug 3.PMID: 19651817 [PubMed - in process]Related articles

Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria.

Merchant ML, Perkins BA, Boratyn GM, Ficociello LH, Wilkey DW, Barati MT, Bertram CC, Page GP, Rovin BH, Warram JH, Krolewski AS, Klein JB.

J Am Soc Nephrol. 2009 Sep;20(9):2065-74. Epub 2009 Jul 30.PMID: 19643930 [PubMed - indexed for MEDLINE]Related articles

Diabetes complications and the renin-angiotensin system.

Perkins BA, Aiello LP, Krolewski AS.

N Engl J Med. 2009 Jul 2;361(1):83-5. No abstract available. PMID: 19571288 [PubMed - indexed for MEDLINE]Related articles

Early nephropathy in type 1 diabetes: the importance of early renal function decline.

Perkins BA, Krolewski AS.

Curr Opin Nephrol Hypertens. 2009 May;18(3):233-40. Review.PMID: 19300247 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.

Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, Ng DP, Placha G, Canani LH, Bochenski J, Waggott D, Merchant ML, Krolewski B, Mirea L, Wanic K, Katavetin P, Kure M, Wolkow P, Dunn JS, Smiles A, Walker WH, Boright AP, Bull SB; DCCT/EDIC Research Group, Doria A, Rogus JJ, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Jun;58(6):1403-10. Epub 2009 Feb 27.PMID: 19252134 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal hyperfiltration and the development of microalbuminuria in type 1 diabetes.

Ficociello LH, Perkins BA, Roshan B, Weinberg JM, Aschengrau A, Warram JH, Krolewski AS.

Diabetes Care. 2009 May;32(5):889-93. Epub 2009 Feb 5.PMID: 19196883 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes.

Niewczas MA, Ficociello LH, Johnson AC, Walker W, Rosolowsky ET, Roshan B, Warram JH, Krolewski AS.

Clin J Am Soc Nephrol. 2009 Jan;4(1):62-70. Epub 2008 Dec 10.PMID: 19073786 [PubMed - indexed for MEDLINE]Related articles

Between hyperfiltration and impairment: demystifying early renal functional changes in diabetic nephropathy.

Rosolowsky ET, Niewczas MA, Ficociello LH, Perkins BA, Warram JH, Krolewski AS.

Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S46-53. Epub 2008 Oct 11. Review.PMID: 18849087 [PubMed - indexed for MEDLINE]Related articles

Exclusion of polymorphisms in carnosinase genes (CNDP1 and CNDP2) as a cause of diabetic nephropathy in type 1 diabetes: results of large case-control and follow-up studies.

Wanic K, Placha G, Dunn J, Smiles A, Warram JH, Krolewski AS.

Diabetes. 2008 Sep;57(9):2547-51.PMID: 18753673 [PubMed - indexed for MEDLINE]Related articlesFree article

High-density single nucleotide polymorphism genome-wide linkage scan for susceptibility genes for diabetic nephropathy in type 1 diabetes: discordant sibpair approach.

Rogus JJ, Poznik GD, Pezzolesi MG, Smiles AM, Dunn J, Walker W, Wanic K, Moczulski D, Canani L, Araki S, Makita Y, Warram JH, Krolewski AS.

Diabetes. 2008 Sep;57(9):2519-26. Epub 2008 Jun 16.PMID: 18559660 [PubMed - indexed for MEDLINE]Related articlesFree article

Exclusion of polymorphisms in carnosinase genes (CNDP1 & CNDP2) as cause of diabetic nephropathy in type 1 diabetes mellitus. Results of large case - control and follow - up studies.

Wanic K, Placha G, Dunn J, Smiles A, Warram JH, Krolewski AS.

Diabetes. 2008 Jun 5. [Epub ahead of print]PMID: 18535186 [PubMed - as supplied by publisher]Related articles

An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.

Ng DP, Nurbaya S, Ye SH, Krolewski AS.

Kidney Int. 2008 Aug;74(4):521-7. Epub 2008 May 21.PMID: 18496509 [PubMed - indexed for MEDLINE]Related articlesFree article

High-normal serum uric acid is associated with impaired glomerular filtration rate in nonproteinuric patients with type 1 diabetes.

Rosolowsky ET, Ficociello LH, Maselli NJ, Niewczas MA, Binns AL, Roshan B, Warram JH, Krolewski AS.

Clin J Am Soc Nephrol. 2008 May;3(3):706-13. Epub 2008 Feb 13.PMID: 18272826 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation at the SLC12A3 locus is unlikely to explain risk for advanced diabetic nephropathy in Caucasians with type 2 diabetes.

Ng DP, Nurbaya S, Choo S, Koh D, Chia KS, Krolewski AS.

Nephrol Dial Transplant. 2008 Jul;23(7):2260-4. Epub 2008 Feb 10.PMID: 18263927 [PubMed - indexed for MEDLINE]Related articles

Association of urinary inflammatory markers and renal decline in microalbuminuric type 1 diabetics.

Wolkow PP, Niewczas MA, Perkins B, Ficociello LH, Lipinski B, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2008 Apr;19(4):789-97. Epub 2008 Feb 6.PMID: 18256362 [PubMed - indexed for MEDLINE]Related articlesFree article

Determinants of progression from microalbuminuria to proteinuria in patients who have type 1 diabetes and are treated with angiotensin-converting enzyme inhibitors.

Ficociello LH, Perkins BA, Silva KH, Finkelstein DM, Ignatowska-Switalska H, Gaciong Z, Cupples LA, Aschengrau A, Warram JH, Krolewski AS.

Clin J Am Soc Nephrol. 2007 May;2(3):461-9. Epub 2007 Mar 27.PMID: 17699452 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association between polymorphisms in the gene encoding protein tyrosine phosphatase 1B (PTPN1) and risk of Type 2 diabetes.

Wanic K, Malecki MT, Klupa T, Warram JH, Sieradzki J, Krolewski AS.

Diabet Med. 2007 Jun;24(6):650-5. Epub 2007 Apr 2.PMID: 17403124 [PubMed - indexed for MEDLINE]Related articles

Identification of a locus modulating serum C-reactive protein levels on chromosome 5p15.

Keenan HA, Poznik GD, Varo N, Schneider J, Almasy L, Warram JH, Duggirala R, Schoenbeck U, Krolewski AS, Doria A.

Atherosclerosis. 2008 Feb;196(2):863-70. Epub 2007 Mar 7.PMID: 17343862 [PubMed - indexed for MEDLINE]Related articlesFree article

Microalbuminuria and the risk for early progressive renal function decline in type 1 diabetes.

Perkins BA, Ficociello LH, Ostrander BE, Silva KH, Weinberg J, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2007 Apr;18(4):1353-61. Epub 2007 Feb 28.PMID: 17329575 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide linkage scan for genes controlling variation in renal function estimated by serum cystatin C levels in extended families with type 2 diabetes.

Placha G, Poznik GD, Dunn J, Smiles A, Krolewski B, Glew T, Puppala S, Schneider J, Rogus JJ, Rich SS, Duggirala R, Warram JH, Krolewski AS.

Diabetes. 2006 Dec;55(12):3358-65.PMID: 17130480 [PubMed - indexed for MEDLINE]Related articlesFree article

A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus.

Ng DP, Placha G, Choo S, Chia KS, Warram JH, Krolewski AS.

Diabetes. 2006 Sep;55(9):2660-3.PMID: 16936219 [PubMed - indexed for MEDLINE]Related articlesFree article

New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals.

Bochenski J, Placha G, Wanic K, Malecki M, Sieradzki J, Warram JH, Krolewski AS.

Diabetes. 2006 Sep;55(9):2626-30.PMID: 16936213 [PubMed - indexed for MEDLINE]Related articlesFree article

Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23.

Dunn JS, Mlynarski WM, Pezzolesi MG, Borowiec M, Powers C, Krolewski AS, Doria A.

Ann Hum Genet. 2006 Sep;70(Pt 5):587-93.PMID: 16907705 [PubMed - indexed for MEDLINE]Related articles

Genetics of Kidneys in Diabetes (GoKinD) study: a genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes.

Mueller PW, Rogus JJ, Cleary PA, Zhao Y, Smiles AM, Steffes MW, Bucksa J, Gibson TB, Cordovado SK, Krolewski AS, Nierras CR, Warram JH.

J Am Soc Nephrol. 2006 Jul;17(7):1782-90. Epub 2006 Jun 14.PMID: 16775037 [PubMed - indexed for MEDLINE]Related articlesFree article

A newly identified mutation in an IPF1 binding site of the insulin gene promoter may predispose to type 2 diabetes mellitus.

Malecki MT, Lebrun P, Pezzolesi M, Warram JH, Krolewski AS, Jhala US.

Diabetologia. 2006 Aug;49(8):1985-7. Epub 2006 Jun 2. No abstract available. PMID: 16741735 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the gene encoding hepatocyte nuclear factor-4alpha and susceptibility to type 2 diabetes in a Polish population.

Wanic K, Malecki MT, Wolkow PP, Klupa T, Skupien J, Bobrek J, Kozek E, Krolewski AS, Sieradzki J.

Diabetes Metab. 2006 Feb;32(1):86-8.PMID: 16523192 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide linkage scan for genes controlling variation in urinary albumin excretion in type II diabetes.

Krolewski AS, Poznik GD, Placha G, Canani L, Dunn J, Walker W, Smiles A, Krolewski B, Fogarty DG, Moczulski D, Araki S, Makita Y, Ng DP, Rogus J, Duggirala R, Rich SS, Warram JH.

Kidney Int. 2006 Jan;69(1):129-36.PMID: 16374433 [PubMed - indexed for MEDLINE]Related articles

A novel framework for sib pair linkage analysis.

Poznik GD, Adamska K, Xu X, Krolewski AS, Rogus JJ.

Am J Hum Genet. 2006 Feb;78(2):222-30. Epub 2005 Dec 8.PMID: 16358216 [PubMed - indexed for MEDLINE]Related articlesFree article

Early nephropathy in type 1 diabetes: a new perspective on who will and who will not progress.

Perkins BA, Krolewski AS.

Curr Diab Rep. 2005 Dec;5(6):455-63. Review.PMID: 16316598 [PubMed - indexed for MEDLINE]Related articles

Risk of diabetic nephropathy in type 1 diabetes is associated with functional polymorphisms in RANTES receptor gene (CCR5): a sex-specific effect.

Mlynarski WM, Placha GP, Wolkow PP, Bochenski JP, Warram JH, Krolewski AS.

Diabetes. 2005 Nov;54(11):3331-5.PMID: 16249462 [PubMed - indexed for MEDLINE]Related articlesFree article

The fatty acid-binding protein-2 A54T polymorphism is associated with renal disease in patients with type 2 diabetes.

Canani LH, Capp C, Ng DP, Choo SG, Maia AL, Nabinger GB, Santos K, Crispim D, Roisemberg I, Krolewski AS, Gross JL.

Diabetes. 2005 Nov;54(11):3326-30.PMID: 16249461 [PubMed - indexed for MEDLINE]Related articlesFree article

Cystatin C and the risk of death.

Perkins BA, Nelson RG, Krolewski AS.

N Engl J Med. 2005 Aug 25;353(8):842-4; author reply 842-4. No abstract available. PMID: 16124125 [PubMed - indexed for MEDLINE]Related articles

Molecular genetic approaches for studying the etiology of diabetic nephropathy.

Ng DP, Krolewski AS.

Curr Mol Med. 2005 Aug;5(5):509-25. Review.PMID: 16101480 [PubMed - indexed for MEDLINE]Related articles

Epidemic of end-stage renal disease in people with diabetes in the United States population: do we know the cause?

Jones CA, Krolewski AS, Rogus J, Xue JL, Collins A, Warram JH.

Kidney Int. 2005 May;67(5):1684-91.PMID: 15840014 [PubMed - indexed for MEDLINE]Related articles

Evidence for different susceptibility genes for proteinuria and ESRD in type 2 diabetes.

Placha G, Canani LH, Warram JH, Krolewski AS.

Adv Chronic Kidney Dis. 2005 Apr;12(2):155-69. Review.PMID: 15822051 [PubMed - indexed for MEDLINE]Related articles

Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: results of a 4-year follow-up study.

Perkins BA, Nelson RG, Ostrander BE, Blouch KL, Krolewski AS, Myers BD, Warram JH.

J Am Soc Nephrol. 2005 May;16(5):1404-12. Epub 2005 Mar 23.PMID: 15788478 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23.

Kim SH, Ma X, Weremowicz S, Ercolino T, Powers C, Mlynarski W, Bashan KA, Warram JH, Mychaleckyj J, Rich SS, Krolewski AS, Doria A.

Diabetes. 2004 May;53(5):1375-84.PMID: 15111509 [PubMed - indexed for MEDLINE]Related articlesFree article

Scrutiny of the glutamine-fructose-6-phosphate transaminase 1 (GFPT1) locus reveals conserved haplotype block structure not associated with diabetic nephropathy.

Ng DP, Walker WH, Chia KS, Choo S, Warram JH, Krolewski AS.

Diabetes. 2004 Mar;53(3):865-9.PMID: 14988277 [PubMed - indexed for MEDLINE]Related articlesFree article

Examination of candidate chromosomal regions for type 2 diabetes reveals a susceptibility locus on human chromosome 8p23.1.

Pezzolesi MG, Nam M, Nagase T, Klupa T, Dunn JS, Mlynarski WM, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2004 Feb;53(2):486-91.PMID: 14747302 [PubMed - indexed for MEDLINE]Related articlesFree article

To: Rippin JD, Patel A, Belyaev ND, Gill GV, Barnett AH, Bain SC (2003) Nitric oxide synthase gene polymorphisms and diabetic nephropathy. Diabetologia 46:426-428.

Ng DP, Warram JH, Krolewski AS.

Diabetologia. 2003 Dec;46(12):1706. Epub 2003 Nov 1. No abstract available. PMID: 14595537 [PubMed - indexed for MEDLINE]Related articles

Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24.

Kim SH, Ma X, Klupa T, Powers C, Pezzolesi M, Warram JH, Rich SS, Krolewski AS, Doria A.

Diabetes. 2003 Aug;52(8):2182-6.PMID: 12882939 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a common risk haplotype for diabetic nephropathy at the protein kinase C-beta1 (PRKCB1) gene locus.

Araki S, Ng DP, Krolewski B, Wyrwicz L, Rogus JJ, Canani L, Makita Y, Haneda M, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2003 Aug;14(8):2015-24.PMID: 12874455 [PubMed - indexed for MEDLINE]Related articlesFree article

Regression of microalbuminuria in type 1 diabetes.

Perkins BA, Ficociello LH, Silva KH, Finkelstein DM, Warram JH, Krolewski AS.

N Engl J Med. 2003 Jun 5;348(23):2285-93.PMID: 12788992 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylenetetrahydrofolate reductase gene polymorphism and susceptibility to diabetic nephropathy in type 1 diabetes.

Makita Y, Moczulski DK, Bochenski J, Smiles AM, Warram JH, Krolewski AS.

Am J Kidney Dis. 2003 Jun;41(6):1189-94.PMID: 12776270 [PubMed - indexed for MEDLINE]Related articles

TGF-beta 1 as a genetic susceptibility locus for advanced diabetic nephropathy in type 1 diabetes mellitus: an investigation of multiple known DNA sequence variants.

Ng DP, Warram JH, Krolewski AS.

Am J Kidney Dis. 2003 Jan;41(1):22-8.PMID: 12500218 [PubMed - indexed for MEDLINE]Related articles

Determinants of the development of diabetes (maturity-onset diabetes of the young-3) in carriers of HNF-1alpha mutations: evidence for parent-of-origin effect.

Klupa T, Warram JH, Antonellis A, Pezzolesi M, Nam M, Malecki MT, Doria A, Rich SS, Krolewski AS.

Diabetes Care. 2002 Dec;25(12):2292-301.PMID: 12453976 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity.

Szabó C, Zanchi A, Komjáti K, Pacher P, Krolewski AS, Quist WC, LoGerfo FW, Horton ES, Veves A.

Circulation. 2002 Nov 19;106(21):2680-6.PMID: 12438293 [PubMed - indexed for MEDLINE]Related articlesFree article