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NON-MHC genes in type 1 diabetes. Family-based association studies and functional studies of disease-associated polymorphisms.

Kristiansen OP.

Dan Med Bull. 2005 Dec;52(4):186-233. Review. No abstract available. PMID: 16764050 [PubMed - indexed for MEDLINE]Related articles

Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3.

Karlsen AE, Størling ZM, Sparre T, Larsen MR, Mahmood A, Størling J, Roepstorff P, Wrzesinski K, Larsen PM, Fey S, Nielsen K, Heding P, Ricordi C, Johannesen J, Kristiansen OP, Christensen UB, Kockum I, Luthman H, Nerup J, Pociot F.

Biochem Biophys Res Commun. 2006 May 26;344(1):406-15. Epub 2006 Mar 29.PMID: 16600178 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 and diabetes: the good, the bad, or the indifferent?

Kristiansen OP, Mandrup-Poulsen T.

Diabetes. 2005 Dec;54 Suppl 2:S114-24. Review.PMID: 16306329 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia.

Nolsøe RL, Kelly JA, Pociot F, Moser KL, Kristiansen OP, Mandrup-Poulsen T, Harley JB.

Genes Immun. 2005 Dec;6(8):699-706.PMID: 16163374 [PubMed - indexed for MEDLINE]Related articles

Is puberty an accelerator of type 1 diabetes in IL6-174CC females?

Gillespie KM, Nolsøe R, Betin VM, Kristiansen OP, Bingley PJ, Mandrup-Poulsen T, Gale EA.

Diabetes. 2005 Apr;54(4):1245-8.PMID: 15793269 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes.

Hamid YH, Rose CS, Urhammer SA, Glümer C, Nolsøe R, Kristiansen OP, Mandrup-Poulsen T, Borch-Johnsen K, Jorgensen T, Hansen T, Pedersen O.

Diabetologia. 2005 Feb;48(2):251-60. Epub 2005 Jan 11.PMID: 15645209 [PubMed - indexed for MEDLINE]Related articles

Is mortalin a candidate gene for T1DM ?

Johannesen J, Pie A, Karlsen AE, Larsen ZM, Jensen A, Vissing H, Kristiansen OP, Pociot F, Nerup J; Danish Study Group of Diabetes in Childhood, Denmark; Danish IDDM Epidemiology and Genetics Group.

Autoimmunity. 2004 Sep-Nov;37(6-7):423-30.PMID: 15621568 [PubMed - indexed for MEDLINE]Related articles

Release of endothelium-associated proteins into blood by injection of heparin in normal subjects and in patients with Type 1 diabetes.

Myrup B, Yokoyama H, Kristiansen OP, Østergaard PB, Olivecrona T.

Diabet Med. 2004 Oct;21(10):1135-40.PMID: 15384962 [PubMed - indexed for MEDLINE]Related articles

Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity.

Kristiansen OP, Karlsen AE, Larsen ZM, Johannesen J, Pociot F, Mandrup-Poulsen T; Danish IDDM Epidemiology and Genetics Group and Danish Study Group of IDDM in Childhood.

Scand J Immunol. 2004 Jun;59(6):582-91.PMID: 15182254 [PubMed - indexed for MEDLINE]Related articles

Genetic and functional evaluation of an interleukin-12 polymorphism (IDDM18) in families with type 1 diabetes.

Bergholdt R, Ghandil P, Johannesen J, Kristiansen OP, Kockum I, Luthman H, Rønningen KS, Nerup J, Julier C, Pociot F.

J Med Genet. 2004 Apr;41(4):e39. No abstract available. PMID: 15060115 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for linkage on chromosome 4p16.1 in Type 1 diabetes Danish families and complete mutation scanning of the WFS1 (Wolframin) gene.

Larsen ZM, Johannesen J, Kristiansen OP, Nerup J, Pociot F; Danish IDDM Epidemiology and Genetics Group; Danish Study Group of IDDM in Childhood.

Diabet Med. 2004 Mar;21(3):218-22.PMID: 15008830 [PubMed - indexed for MEDLINE]Related articles

Association of a functional 17beta-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females.

Kristiansen OP, Nolsøe RL, Larsen L, Gjesing AM, Johannesen J, Larsen ZM, Lykkesfeldt AE, Karlsen AE, Pociot F, Mandrup-Poulsen T; DIEGG; DSGD.

Hum Mol Genet. 2003 May 15;12(10):1101-10.PMID: 12719374 [PubMed - indexed for MEDLINE]Related articlesFree article

Complete mutation scan of the human Fas ligand gene: linkage studies in Type I diabetes mellitus families.

Nolsøe RL, Kristiansen OP, Larsen ZM, Johannesen J, Pociot F, Mandrup-Poulsen T.

Diabetologia. 2002 Jan;45(1):134-9.PMID: 11845233 [PubMed - indexed for MEDLINE]Related articles

Linkage of the human inducible nitric oxide synthase gene to type 1 diabetes.

Johannesen J, Pie A, Pociot F, Kristiansen OP, Karlsen AE, Nerup J; Danish Study Group of Diabetes in Childhood. The Danish Insulin-dependent Diabetes Mellitus Epidemiology and Genetics Group.

J Clin Endocrinol Metab. 2001 Jun;86(6):2792-6.PMID: 11397889 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of new polymorphisms in the 5' UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level.

Bergholdt R, Larsen ZM, Andersen NA, Johannesen J, Kristiansen OP, Mandrup-Poulsen T, Nerup J, Pociot F; Danish Study Group of IDDM in Childhood; Danish IDDM Epidemiology and Genetics Group.

Genes Immun. 2000 Dec;1(8):495-500.PMID: 11197691 [PubMed - indexed for MEDLINE]Related articlesFree article

CTLA-4 in autoimmune diseases--a general susceptibility gene to autoimmunity?

Kristiansen OP, Larsen ZM, Pociot F.

Genes Immun. 2000 Feb;1(3):170-84. Review.PMID: 11196709 [PubMed - indexed for MEDLINE]Related articlesFree article

No evidence for linkage in the promoter region of the inducible nitric oxide synthase gene (NOS2) in a Danish type 1 diabetes population.

Johannesen J, Pociot F, Kristiansen OP, Karlsen AE, Nerup J; DIEGG and DSGD. Danish IDDM Epidemiology and Genetics Group. Danish Study Group of Diabetis in Childhood.

Genes Immun. 2000 Aug;1(6):362-6.PMID: 11196682 [PubMed - indexed for MEDLINE]Related articlesFree article

The intercellular adhesion molecule-1 K469E polymorphism in type 1 diabetes.

Kristiansen OP, Nolsøe RL, Holst H, Reker S, Larsen ZM, Johannesen J, Nerup J, Pociot F, Mandrup-Poulsen T; Danish Study Group of IDDM in Childhood.

Immunogenetics. 2000 Nov;52(1-2):107-11.PMID: 11132145 [PubMed - indexed for MEDLINE]Related articles

Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type I diabetes mellitus. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group.

Nolsøe RL, Kristiansen OP, Sangthongpitag K, Larsen ZM, Johannesen J, Karlsen AE, Pociot F, Nerup J, Verge CF, Mandrup-Poulsen T.

Diabetologia. 2000 Jun;43(6):800-8.PMID: 10907126 [PubMed - indexed for MEDLINE]Related articles

NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epidemiology and Genetics Group.

Hansen L, Jensen JN, Urioste S, Petersen HV, Pociot F, Eiberg H, Kristiansen OP, Hansen T, Serup P, Nerup J, Pedersen O.

Diabetes. 2000 May;49(5):876-8.PMID: 10905500 [PubMed - indexed for MEDLINE]Related articlesFree article

IDDM7 links to insulin-dependent diabetes mellitus in Danish multiplex families but linkage is not explained by novel polymorphisms in the candidate gene GALNT3. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group.

Kristiansen OP, Pociot F, Bennett EP, Clausen H, Johannesen J, Nerup J, Mandrup-Poulsen T.

Hum Mutat. 2000 Mar;15(3):295-6.PMID: 10679951 [PubMed - indexed for MEDLINE]Related articles

Linkage disequilibrium testing of four interleukin-1 gene-cluster polymorphisms in Danish multiplex families with insulin-dependent diabetes mellitus.

Kristiansen OP, Pociot F, Johannesen J, Bergholdt R, Dinarello CA, Nerup J, Mandrup-Poulsen T.

Cytokine. 2000 Feb;12(2):171-5.PMID: 10671304 [PubMed - indexed for MEDLINE]Related articles

IDDM12 (CTLA4) on 2q33 and IDDM13 on 2q34 in genetic susceptibility to type 1 diabetes (insulin-dependent).

Larsen ZM, Kristiansen OP, Mato E, Johannesen J, Puig-Domingo M, de Leiva A, Nerup J, Pociot F.

Autoimmunity. 1999;31(1):35-42.PMID: 10593567 [PubMed - indexed for MEDLINE]Related articles

No linkage of P187S polymorphism in NAD(P)H: quinone oxidoreductase (NQO1/DIA4) and type 1 diabetes in the Danish population. DIEGG and DSGD. Danish IDDM Epidemiology and Genetics Group and The Danish Study Group of Diabetes in Childhood.

Kristiansen OP, Larsen ZM, Johannesen J, Nerup J, Mandrup-Poulsen T, Pociot F.

Hum Mutat. 1999;14(1):67-70.PMID: 10447260 [PubMed - indexed for MEDLINE]Related articles

A population-based survey of frequencies of self-reported spontaneous and induced abortions in Danish women with Type 1 diabetes mellitus. Danish IDDM Epidemiology and Genetics Group.

Lorenzen T, Pociot F, Johannesen J, Kristiansen OP, Nerup J.

Diabet Med. 1999 Jun;16(6):472-6.PMID: 10391394 [PubMed - indexed for MEDLINE]Related articles

[Markers for risk of IDDM in children of Danish patients with IDDM. A population-based, historical prospective study]

Lorenzen T, Pociot F, Stilgren LS, Kristiansen OP, Johannesen J, Olsen PB, Walmar A, Larsen AV, Albrechtsen NC, Eskildsen PC, Andersen OO, Nerup J.

Ugeskr Laeger. 1999 Feb 15;161(7):953-8. Danish. PMID: 10051805 [PubMed - indexed for MEDLINE]Related articles

Predictors of IDDM recurrence risk in offspring of Danish IDDM patients. Danish IDDM Epidemiology and Genetics Group.

Lorenzen T, Pociot F, Stilgren L, Kristiansen OP, Johannesen J, Olsen PB, Walmar A, Larsen A, Albrechtsen NC, Eskildsen PC, Andersen OO, Nerup J.

Diabetologia. 1998 Jun;41(6):666-73.PMID: 9662048 [PubMed - indexed for MEDLINE]Related articles

Linkage and association between a CD4 gene polymorphism and IDDM in Danish IDDM patients. The Danish IDDM Epidemiology and Genetics Group, and The Danish Study Group of Diabetes in Childhood.

Kristiansen OP, Zamani M, Johannesen J, Mandrup-Poulsen T, Cassiman JJ, Nerup J, Pociot F.

Diabetes. 1998 Feb;47(2):281-3. No abstract available. PMID: 9519727 [PubMed - indexed for MEDLINE]Related articles