PubMed

Network analysis of genes regulated in renal diseases: implications for a molecular-based classification.

Bhavnani SK, Eichinger F, Martini S, Saxman P, Jagadish HV, Kretzler M.

BMC Bioinformatics. 2009 Sep 17;10 Suppl 9:S3.PMID: 19761573 [PubMed - in process]Related articlesFree article

Mouse Models of Diabetic Nephropathy.

Brosius FC 3rd, Alpers CE, Bottinger EP, Breyer MD, Coffman TM, Gurley SB, Harris RC, Kakoki M, Kretzler M, Leiter EH, Levi M, McIndoe RA, Sharma K, Smithies O, Susztak K, Takahashi N, Takahashi T; for the Animal Models of Diabetic Complications Consortium.

J Am Soc Nephrol. 2009 Sep 3. [Epub ahead of print]PMID: 19729434 [PubMed - as supplied by publisher]Related articles

The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.

Zhao W, Thacker SG, Hodgin JB, Zhang H, Wang JH, Park JL, Randolph A, Somers EC, Pennathur S, Kretzler M, Brosius FC 3rd, Kaplan MJ.

J Immunol. 2009 Aug 15;183(4):2729-40. Epub 2009 Jul 20.PMID: 19620300 [PubMed - indexed for MEDLINE]Related articles

How to build a tight but permeable glomerular junction.

Martini S, Kretzler M.

J Am Soc Nephrol. 2009 Jul;20(7):1420-1. Epub 2009 Jun 11. No abstract available. PMID: 19520750 [PubMed - indexed for MEDLINE]Related articles

Renal gene and protein expression signatures for prediction of kidney disease progression.

Ju W, Eichinger F, Bitzer M, Oh J, McWeeney S, Berthier CC, Shedden K, Cohen CD, Henger A, Krick S, Kopp JB, Stoeckert CJ Jr, Dikman S, Schröppel B, Thomas DB, Schlondorff D, Kretzler M, Böttinger EP.

Am J Pathol. 2009 Jun;174(6):2073-85.PMID: 19465643 [PubMed - indexed for MEDLINE]Related articles

Urine podocyte mRNAs mark progression of renal disease.

Sato Y, Wharram BL, Lee SK, Wickman L, Goyal M, Venkatareddy M, Chang JW, Wiggins JE, Lienczewski C, Kretzler M, Wiggins RC.

J Am Soc Nephrol. 2009 May;20(5):1041-52. Epub 2009 Apr 23.PMID: 19389856 [PubMed - indexed for MEDLINE]Related articles

Role of basic fibroblast growth factor (FGF-2) in diabetic nephropathy and mechanisms of its induction by hyperglycemia in human renal fibroblasts.

Vasko R, Koziolek M, Ikehata M, Rastaldi MP, Jung K, Schmid H, Kretzler M, Müller GA, Strutz F.

Am J Physiol Renal Physiol. 2009 Jun;296(6):F1452-63. Epub 2009 Mar 11.PMID: 19279131 [PubMed - indexed for MEDLINE]Related articles

Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays.

Moll AG, Lindenmeyer MT, Kretzler M, Nelson PJ, Zimmer R, Cohen CD.

PLoS One. 2009;4(3):e4702. Epub 2009 Mar 11.PMID: 19277110 [PubMed - indexed for MEDLINE]Related articlesFree article

[Transcriptomics illustrate a deadly TRAIL to diabetic nephropathy]

Benito-Martín A, Ucero AC, Santamaría B, Lorz C, Kretzler M, Rastaldi MP, Sánchez-Niño MD, Sanz A, Izquierdo MC, Ruiz Ortega M, Egido J, Ortiz A.

Nefrologia. 2009;29(1):13-9. doi: 10.3265/Nefrologia.2009.29.1.13.1.en.full.pdf. Review. Spanish. PMID: 19240767 [PubMed - indexed for MEDLINE]Related articlesFree article

[Gene expression analyses of kidney biopsies: the European renal cDNA bank--Kröner-Fresenius biopsy bank]

Cohen CD, Kretzler M.

Pathologe. 2009 Mar;30(2):101-4. German. PMID: 19224215 [PubMed - indexed for MEDLINE]Related articles

A pilot study of gene expression-based categorization of pancreas transplant biopsies.

Luan FL, Trillsch F, Henger A, Eichinger F, Norman S, Appelman H, Kretzler M.

Transplantation. 2009 Jan 27;87(2):222-6. Erratum in: Transplantation. 2009 Mar 27;87(6):945. PMID: 19155976 [PubMed - indexed for MEDLINE]Related articles

Palladin is a dynamic actin-associated protein in podocytes.

Endlich N, Schordan E, Cohen CD, Kretzler M, Lewko B, Welsch T, Kriz W, Otey CA, Endlich K; European Renal cDNA Bank Consortium.

Kidney Int. 2009 Jan;75(2):214-26. Epub 2008 Oct 1.PMID: 19116644 [PubMed - indexed for MEDLINE]Related articles

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy.

Berthier CC, Zhang H, Schin M, Henger A, Nelson RG, Yee B, Boucherot A, Neusser MA, Cohen CD, Carter-Su C, Argetsinger LS, Rastaldi MP, Brosius FC, Kretzler M.

Diabetes. 2009 Feb;58(2):469-77. Epub 2008 Nov 18.PMID: 19017763 [PubMed - indexed for MEDLINE]Related articlesFree article

The MIF receptor CD74 in diabetic podocyte injury.

Sanchez-Niño MD, Sanz AB, Ihalmo P, Lassila M, Holthofer H, Mezzano S, Aros C, Groop PH, Saleem MA, Mathieson PW, Langham R, Kretzler M, Nair V, Lemley KV, Nelson RG, Mervaala E, Mattinzoli D, Rastaldi MP, Ruiz-Ortega M, Martin-Ventura JL, Egido J, Ortiz A.

J Am Soc Nephrol. 2009 Feb;20(2):353-62. Epub 2008 Oct 8.PMID: 18842989 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of chemokine CCL5 expression in monocytes/macrophages and renal cells by Y-box protein-1.

Raffetseder U, Rauen T, Djudjaj S, Kretzler M, En-Nia A, Tacke F, Zimmermann HW, Nelson PJ, Frye BC, Floege J, Stefanidis I, Weber C, Mertens PR.

Kidney Int. 2009 Jan;75(2):185-96. Epub 2008 Sep 17.PMID: 18800033 [PubMed - indexed for MEDLINE]Related articles

Proteinuria and hyperglycemia induce endoplasmic reticulum stress.

Lindenmeyer MT, Rastaldi MP, Ikehata M, Neusser MA, Kretzler M, Cohen CD, Schlöndorff D.

J Am Soc Nephrol. 2008 Nov;19(11):2225-36. Epub 2008 Sep 5.PMID: 18776125 [PubMed - indexed for MEDLINE]Related articlesFree article

Defining human diabetic nephropathy on the molecular level: integration of transcriptomic profiles with biological knowledge.

Martini S, Eichinger F, Nair V, Kretzler M.

Rev Endocr Metab Disord. 2008 Dec;9(4):267-74. Review.PMID: 18704688 [PubMed - indexed for MEDLINE]Related articles

Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis.

Cohen CD, Lindenmeyer MT, Eichinger F, Hahn A, Seifert M, Moll AG, Schmid H, Kiss E, Gröne E, Gröne HJ, Kretzler M, Werner T, Nelson PJ.

PLoS One. 2008 Aug 13;3(8):e2937.PMID: 18698414 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy.

Zhang H, Saha J, Byun J, Schin M, Lorenz M, Kennedy RT, Kretzler M, Feldman EL, Pennathur S, Brosius FC 3rd.

Am J Physiol Renal Physiol. 2008 Oct;295(4):F1071-81. Epub 2008 Jul 30.PMID: 18667486 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic analysis in nephrology--towards systems biology and systematic medicine?

Neusser MA, Lindenmeyer MT, Kretzler M, Cohen CD.

Nephrol Ther. 2008 Oct;4(5):306-11. Epub 2008 Jun 30. Review.PMID: 18586598 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2J mice.

Wiggin TD, Kretzler M, Pennathur S, Sullivan KA, Brosius FC, Feldman EL.

Endocrinology. 2008 Oct;149(10):4928-37. Epub 2008 Jun 26.PMID: 18583417 [PubMed - indexed for MEDLINE]Related articlesFree article

From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy.

Qian Y, Feldman E, Pennathur S, Kretzler M, Brosius FC 3rd.

Diabetes. 2008 Jun;57(6):1439-45. Review. No abstract available. PMID: 18511444 [PubMed - indexed for MEDLINE]Related articlesFree article

IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.

Murphy M, Docherty NG, Griffin B, Howlin J, McArdle E, McMahon R, Schmid H, Kretzler M, Droguett A, Mezzano S, Brady HR, Furlong F, Godson C, Martin F.

J Am Soc Nephrol. 2008 Sep;19(9):1672-80. Epub 2008 May 28.PMID: 18508967 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of PINCH-2 in regulation of glomerular cell shape change and fibronectin matrix deposition.

Shi X, Qu H, Kretzler M, Wu C.

Am J Physiol Renal Physiol. 2008 Jul;295(1):F253-63. Epub 2008 May 14.PMID: 18480182 [PubMed - indexed for MEDLINE]Related articlesFree article

Maternal environment interacts with modifier genes to influence progression of nephrotic syndrome.

Ratelade J, Lavin TA, Muda AO, Morisset L, Mollet G, Boyer O, Chen DS, Henger A, Kretzler M, Hubner N, Théry C, Gubler MC, Montagutelli X, Antignac C, Esquivel EL.

J Am Soc Nephrol. 2008 Aug;19(8):1491-9. Epub 2008 Apr 2.PMID: 18385421 [PubMed - indexed for MEDLINE]Related articlesFree article

Notch inhibition reverses kidney failure.

Kretzler M, Allred L.

Nat Med. 2008 Mar;14(3):246-7. No abstract available. PMID: 18323843 [PubMed - indexed for MEDLINE]Related articles

The death ligand TRAIL in diabetic nephropathy.

Lorz C, Benito-Martín A, Boucherot A, Ucero AC, Rastaldi MP, Henger A, Armelloni S, Santamaría B, Berthier CC, Kretzler M, Egido J, Ortiz A.

J Am Soc Nephrol. 2008 May;19(5):904-14. Epub 2008 Feb 20.PMID: 18287563 [PubMed - indexed for MEDLINE]Related articlesFree article

Modification of kidney barrier function by the urokinase receptor.

Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J.

Nat Med. 2008 Jan;14(1):55-63. Epub 2007 Dec 16.PMID: 18084301 [PubMed - indexed for MEDLINE]Related articles

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.

Higgins DF, Kimura K, Bernhardt WM, Shrimanker N, Akai Y, Hohenstein B, Saito Y, Johnson RS, Kretzler M, Cohen CD, Eckardt KU, Iwano M, Haase VH.

J Clin Invest. 2007 Dec;117(12):3810-20.PMID: 18037992 [PubMed - indexed for MEDLINE]Related articlesFree article

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy.

Walsh DW, Roxburgh SA, McGettigan P, Berthier CC, Higgins DG, Kretzler M, Cohen CD, Mezzano S, Brazil DP, Martin F.

Biochim Biophys Acta. 2008 Jan;1782(1):10-21. Epub 2007 Oct 11.PMID: 17980714 [PubMed - indexed for MEDLINE]Related articles

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease.

Sever S, Altintas MM, Nankoe SR, Möller CC, Ko D, Wei C, Henderson J, del Re EC, Hsing L, Erickson A, Cohen CD, Kretzler M, Kerjaschki D, Rudensky A, Nikolic B, Reiser J.

J Clin Invest. 2007 Aug;117(8):2095-104.PMID: 17671649 [PubMed - indexed for MEDLINE]Related articlesFree article

Differentially spliced isoforms of FAT1 are asymmetrically distributed within migrating cells.

Braun GS, Kretzler M, Heider T, Floege J, Holzman LB, Kriz W, Moeller MJ.

J Biol Chem. 2007 Aug 3;282(31):22823-33. Epub 2007 May 11.PMID: 17500054 [PubMed - indexed for MEDLINE]Related articlesFree article

Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.

Lindenmeyer MT, Kretzler M, Boucherot A, Berra S, Yasuda Y, Henger A, Eichinger F, Gaiser S, Schmid H, Rastaldi MP, Schrier RW, Schlöndorff D, Cohen CD.

J Am Soc Nephrol. 2007 Jun;18(6):1765-76. Epub 2007 May 2.PMID: 17475821 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of filtrin in human glomerular diseases.

Ihalmo P, Schmid H, Rastaldi MP, Mattinzoli D, Langham RG, Luimula P, Kilpikari R, Lassila M, Gilbert RE, Kerjaschki D, Kretzler M, Holthöfer H.

Nephrol Dial Transplant. 2007 Jul;22(7):1903-9. Epub 2007 Apr 18.PMID: 17442742 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of the chemokine receptor CCR1 in human renal allografts.

Mayer V, Hudkins KL, Heller F, Schmid H, Kretzler M, Brandt U, Anders HJ, Regele H, Nelson PJ, Alpers CE, Schlöndorff D, Segerer S.

Nephrol Dial Transplant. 2007 Jun;22(6):1720-9. Epub 2007 Feb 13.PMID: 17298994 [PubMed - indexed for MEDLINE]Related articlesFree article

The contribution of B cells to renal interstitial inflammation.

Heller F, Lindenmeyer MT, Cohen CD, Brandt U, Draganovici D, Fischereder M, Kretzler M, Anders HJ, Sitter T, Mosberger I, Kerjaschki D, Regele H, Schlöndorff D, Segerer S.

Am J Pathol. 2007 Feb;170(2):457-68.PMID: 17255314 [PubMed - indexed for MEDLINE]Related articlesFree article

TGF-beta1 regulates the PINCH-1-integrin-linked kinase-alpha-parvin complex in glomerular cells.

Jung KY, Chen K, Kretzler M, Wu C.

J Am Soc Nephrol. 2007 Jan;18(1):66-73. Epub 2006 Dec 13.PMID: 17167118 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of TRPC6 channel in acquired forms of proteinuric kidney disease.

Möller CC, Wei C, Altintas MM, Li J, Greka A, Ohse T, Pippin JW, Rastaldi MP, Wawersik S, Schiavi S, Henger A, Kretzler M, Shankland SJ, Reiser J.

J Am Soc Nephrol. 2007 Jan;18(1):29-36. Epub 2006 Dec 13.PMID: 17167110 [PubMed - indexed for MEDLINE]Related articlesFree article

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy.

Schmid H, Boucherot A, Yasuda Y, Henger A, Brunner B, Eichinger F, Nitsche A, Kiss E, Bleich M, Gröne HJ, Nelson PJ, Schlöndorff D, Cohen CD, Kretzler M; European Renal cDNA Bank (ERCB) Consortium.

Diabetes. 2006 Nov;55(11):2993-3003.PMID: 17065335 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of endothelin receptors for renal protection and survival in hypertension: waiting for clinical trials.

Barton M, Mullins JJ, Bailey MA, Kretzler M.

Hypertension. 2006 Nov;48(5):834-7. Epub 2006 Oct 2. Review. No abstract available. PMID: 17015776 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.

Patole PS, Pawar RD, Lech M, Zecher D, Schmidt H, Segerer S, Ellwart A, Henger A, Kretzler M, Anders HJ.

Nephrol Dial Transplant. 2006 Nov;21(11):3062-73. Epub 2006 Sep 5.PMID: 16954173 [PubMed - indexed for MEDLINE]Related articlesFree article

Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex.

Wienecke R, Fackler I, Linsenmaier U, Mayer K, Licht T, Kretzler M.

Am J Kidney Dis. 2006 Sep;48(3):e27-9.PMID: 16931204 [PubMed - indexed for MEDLINE]Related articles

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice.

Ding M, Cui S, Li C, Jothy S, Haase V, Steer BM, Marsden PA, Pippin J, Shankland S, Rastaldi MP, Cohen CD, Kretzler M, Quaggin SE.

Nat Med. 2006 Sep;12(9):1081-7. Epub 2006 Aug 13.PMID: 16906157 [PubMed - indexed for MEDLINE]Related articles

Gene expression profiling analysis in nephrology: towards molecular definition of renal disease.

Yasuda Y, Cohen CD, Henger A, Kretzler M; European Renal cDNA Bank (ERCB) Consortium.

Clin Exp Nephrol. 2006 Jun;10(2):91-8. Review.PMID: 16791393 [PubMed - indexed for MEDLINE]Related articles

Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

El-Aouni C, Herbach N, Blattner SM, Henger A, Rastaldi MP, Jarad G, Miner JH, Moeller MJ, St-Arnaud R, Dedhar S, Holzman LB, Wanke R, Kretzler M.

J Am Soc Nephrol. 2006 May;17(5):1334-44. Epub 2006 Apr 12.PMID: 16611717 [PubMed - indexed for MEDLINE]Related articlesFree article

Glomerular podocytes contain neuron-like functional synaptic vesicles.

Rastaldi MP, Armelloni S, Berra S, Calvaresi N, Corbelli A, Giardino LA, Li M, Wang GQ, Fornasieri A, Villa A, Heikkila E, Soliymani R, Boucherot A, Cohen CD, Kretzler M, Nitsche A, Ripamonti M, Malgaroli A, Pesaresi M, Forloni GL, Schlöndorff D, Holthofer H, D'Amico G.

FASEB J. 2006 May;20(7):976-8. Epub 2006 Apr 3.PMID: 16585060 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins.

Cohen CD, Klingenhoff A, Boucherot A, Nitsche A, Henger A, Brunner B, Schmid H, Merkle M, Saleem MA, Koller KP, Werner T, Gröne HJ, Nelson PJ, Kretzler M.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5682-7. Epub 2006 Mar 31.PMID: 16581909 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of the chemokine receptor CXCR1 in human glomerular diseases.

Segerer S, Henger A, Schmid H, Kretzler M, Draganovici D, Brandt U, Noessner E, Nelson PJ, Kerjaschki D, Schlöndorff D, Regele H.

Kidney Int. 2006 May;69(10):1765-73.PMID: 16541017 [PubMed - indexed for MEDLINE]Related articles

Molecular approaches to chronic kidney disease.

Schmid H, Henger A, Kretzler M.

Curr Opin Nephrol Hypertens. 2006 Mar;15(2):123-9. Review.PMID: 16481877 [PubMed - indexed for MEDLINE]Related articles

Differential expression of profibrotic and growth factors in chronic allograft nephropathy.

Hotchkiss H, Chu TT, Hancock WW, Schröppel B, Kretzler M, Schmid H, Liu Y, Dikman S, Akalin E.

Transplantation. 2006 Feb 15;81(3):342-9.PMID: 16477218 [PubMed - indexed for MEDLINE]Related articles