PubMed

Inter-individual variation of dietary fat-induced mesoderm specific transcript in adipose tissue within inbred mice is not caused by altered promoter methylation.

Koza RA, Rogers P, Kozak LP.

Epigenetics. 2009 Oct 9;4(7). [Epub ahead of print]PMID: 19875931 [PubMed - as supplied by publisher]Related articles

Have we entered the brown adipose tissue renaissance?

Ravussin E, Kozak LP.

Obes Rev. 2009 May;10(3):265-8. Epub 2009 Jan 19. Review.PMID: 19175509 [PubMed - indexed for MEDLINE]Related articles

UCP1: its involvement and utility in obesity.

Kozak LP, Anunciado-Koza R.

Int J Obes (Lond). 2008 Dec;32 Suppl 7:S32-8. Review.PMID: 19136989 [PubMed - indexed for MEDLINE]Related articlesFree article

Inactivation of UCP1 and the glycerol phosphate cycle synergistically increases energy expenditure to resist diet-induced obesity.

Anunciado-Koza R, Ukropec J, Koza RA, Kozak LP.

J Biol Chem. 2008 Oct 10;283(41):27688-97. Epub 2008 Aug 4.PMID: 18678870 [PubMed - indexed for MEDLINE]Related articlesFree article

Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance.

Nikonova L, Koza RA, Mendoza T, Chao PM, Curley JP, Kozak LP.

FASEB J. 2008 Nov;22(11):3925-37. Epub 2008 Jul 21.PMID: 18644838 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat.

Xue B, Rim JS, Hogan JC, Coulter AA, Koza RA, Kozak LP.

J Lipid Res. 2007 Jan;48(1):41-51. Epub 2006 Oct 14.PMID: 17041251 [PubMed - indexed for MEDLINE]Related articlesFree article

UCP1-independent thermogenesis in white adipose tissue of cold-acclimated Ucp1-/- mice.

Ukropec J, Anunciado RP, Ravussin Y, Hulver MW, Kozak LP.

J Biol Chem. 2006 Oct 20;281(42):31894-908. Epub 2006 Aug 16.PMID: 16914547 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effect of amaranth oil and intermittent hypoxic training on ultrastructural and metabolic changes in the liver induced by fluorine and low doses of radiation]

Hzhehots'kyĭ MP, Konyk UV, Kozak LP, Kovalyshyn VI.

Fiziol Zh. 2006;52(3):90-8. Ukrainian. PMID: 16909762 [PubMed - indexed for MEDLINE]Related articles

Changes in gene expression foreshadow diet-induced obesity in genetically identical mice.

Koza RA, Nikonova L, Hogan J, Rim JS, Mendoza T, Faulk C, Skaf J, Kozak LP.

PLoS Genet. 2006 May;2(5):e81. Epub 2006 May 26.PMID: 16733553 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress.

Ukropec J, Anunciado RV, Ravussin Y, Kozak LP.

Endocrinology. 2006 May;147(5):2468-80. Epub 2006 Feb 9.PMID: 16469807 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling proteins: current status and therapeutic prospects.

Nedergaard J, Ricquier D, Kozak LP.

EMBO Rep. 2005 Oct;6(10):917-21. No abstract available. PMID: 16179945 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots.

Xue B, Coulter A, Rim JS, Koza RA, Kozak LP.

Mol Cell Biol. 2005 Sep;25(18):8311-22.PMID: 16135818 [PubMed - indexed for MEDLINE]Related articlesFree article

Contributions of dysregulated energy metabolism to type 2 diabetes development in NZO/H1Lt mice with polygenic obesity.

Koza RA, Flurkey K, Graunke DM, Braun C, Pan HJ, Reifsnyder PC, Kozak LP, Leiter EH.

Metabolism. 2004 Jun;53(6):799-808.PMID: 15164332 [PubMed - indexed for MEDLINE]Related articles

Sequestration of thermogenic transcription factors in the cytoplasm during development of brown adipose tissue.

Rim JS, Xue B, Gawronska-Kozak B, Kozak LP.

J Biol Chem. 2004 Jun 11;279(24):25916-26. Epub 2004 Apr 8.PMID: 15073176 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling protein 2, but not uncoupling protein 1, is expressed in the female mouse reproductive tract.

Rousset S, Alves-Guerra MC, Ouadghiri-Bencherif S, Kozak LP, Miroux B, Richard D, Bouillaud F, Ricquier D, Cassard-Doulcier AM.

J Biol Chem. 2003 Nov 14;278(46):45843-7. Epub 2003 Aug 26.PMID: 12941933 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in type 2 diabetes--related traits in mouse strains susceptible to diet-induced obesity.

Rossmeisl M, Rim JS, Koza RA, Kozak LP.

Diabetes. 2003 Aug;52(8):1958-66.PMID: 12882911 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary fat interacts with QTLs controlling induction of Pgc-1 alpha and Ucp1 during conversion of white to brown fat.

Coulter AA, Bearden CM, Liu X, Koza RA, Kozak LP.

Physiol Genomics. 2003 Jul 7;14(2):139-47.PMID: 12746468 [PubMed - indexed for MEDLINE]Related articles

[The role of oxidative metabolism in development of adaptation effect after exposure to ethanol and pulsed hypoxic training]

Kozak LP, Terlets'ka OI, Koval'chuk SM.

Fiziol Zh. 2002;48(6):74-9. Ukrainian. PMID: 12577474 [PubMed - indexed for MEDLINE]Related articles

Paradoxical resistance to diet-induced obesity in UCP1-deficient mice.

Liu X, Rossmeisl M, McClaine J, Riachi M, Harper ME, Kozak LP.

J Clin Invest. 2003 Feb;111(3):399-407. Erratum in: J Clin Invest. 2003 Mar;111(5):759. PMID: 12569166 [PubMed - indexed for MEDLINE]Related articlesFree article

Lethal hypoglycemic ketosis and glyceroluria in mice lacking both the mitochondrial and the cytosolic glycerol phosphate dehydrogenases.

Brown LJ, Koza RA, Marshall L, Kozak LP, MacDonald MJ.

J Biol Chem. 2002 Sep 6;277(36):32899-904. Epub 2002 Jul 1.PMID: 12093800 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal thyroid thermogenesis but reduced viability and adiposity in mice lacking the mitochondrial glycerol phosphate dehydrogenase.

Brown LJ, Koza RA, Everett C, Reitman ML, Marshall L, Fahien LA, Kozak LP, MacDonald MJ.

J Biol Chem. 2002 Sep 6;277(36):32892-8. Epub 2002 Jul 1.PMID: 12093799 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulatory motifs for CREB-binding protein and Nfe2l2 transcription factors in the upstream enhancer of the mitochondrial uncoupling protein 1 gene.

Rim JS, Kozak LP.

J Biol Chem. 2002 Sep 13;277(37):34589-600. Epub 2002 Jun 25.PMID: 12084707 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiposity and the development of diabetes in mouse genetic models.

Kozak LP, Rossmeisl M.

Ann N Y Acad Sci. 2002 Jun;967:80-7. Review.PMID: 12079838 [PubMed - indexed for MEDLINE]Related articles

Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance.

Guerra C, Navarro P, Valverde AM, Arribas M, Brüning J, Kozak LP, Kahn CR, Benito M.

J Clin Invest. 2001 Oct;108(8):1205-13.PMID: 11602628 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of fasting on muscle mitochondrial energetics and fatty acid metabolism in Ucp3(-/-) and wild-type mice.

Bézaire V, Hofmann W, Kramer JK, Kozak LP, Harper ME.

Am J Physiol Endocrinol Metab. 2001 Nov;281(5):E975-82.PMID: 11595653 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of genetic background on thermoregulation and fatty acid-induced uncoupling of mitochondria in UCP1-deficient mice.

Hofmann WE, Liu X, Bearden CM, Harper ME, Kozak LP.

J Biol Chem. 2001 Apr 13;276(15):12460-5. Epub 2001 Jan 24.PMID: 11279075 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II as a trophic factor of white adipose tissue: stimulation of adipose cell formation.

Saint-Marc P, Kozak LP, Ailhaud G, Darimont C, Negrel R.

Endocrinology. 2001 Jan;142(1):487-92.PMID: 11145613 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic studies of brown adipocyte induction.

Kozak LP.

J Nutr. 2000 Dec;130(12):3132S-3133S. Review.PMID: 11110889 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling diet and diabetes.

Kozak LP.

Nat Med. 2000 Oct;6(10):1092-3. No abstract available. PMID: 11017131 [PubMed - indexed for MEDLINE]Related articles

Increased mitochondrial proton leak in skeletal muscle mitochondria of UCP1-deficient mice.

Monemdjou S, Hofmann WE, Kozak LP, Harper ME.

Am J Physiol Endocrinol Metab. 2000 Oct;279(4):E941-6.PMID: 11001779 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial uncoupling proteins in energy expenditure.

Kozak LP, Harper ME.

Annu Rev Nutr. 2000;20:339-63. Review.PMID: 10940338 [PubMed - indexed for MEDLINE]Related articles

Synergistic gene interactions control the induction of the mitochondrial uncoupling protein (Ucp1) gene in white fat tissue.

Koza RA, Hohmann SM, Guerra C, Rossmeisl M, Kozak LP.

J Biol Chem. 2000 Nov 3;275(44):34486-92.PMID: 10931824 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3.

Gong DW, Monemdjou S, Gavrilova O, Leon LR, Marcus-Samuels B, Chou CJ, Everett C, Kozak LP, Li C, Deng C, Harper ME, Reitman ML.

J Biol Chem. 2000 May 26;275(21):16251-7.PMID: 10748195 [PubMed - indexed for MEDLINE]Related articlesFree article

Cig30 and Pitx3 genes are arranged in a partially overlapping tail-to-tail array resulting in complementary transcripts.

Tvrdik P, Asadi A, Kozak LP, Nuglozeh E, Parente F, Nedergaard J, Jacobsson A.

J Biol Chem. 1999 Sep 10;274(37):26387-92.PMID: 10473596 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondria uncoupling proteins and obesity: molecular and genetic aspects of UCP1.

Kozak LP, Koza RA.

Int J Obes Relat Metab Disord. 1999 Jun;23 Suppl 6:S33-7. Review.PMID: 10454119 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial proton leak in brown adipose tissue mitochondria of Ucp1-deficient mice is GDP insensitive.

Monemdjou S, Kozak LP, Harper ME.

Am J Physiol. 1999 Jun;276(6 Pt 1):E1073-82.PMID: 10362620 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation.

Guerra C, Koza RA, Walsh K, Kurtz DM, Wood PA, Kozak LP.

J Clin Invest. 1998 Nov 1;102(9):1724-31.PMID: 9802886 [PubMed - indexed for MEDLINE]Related articlesFree article

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity.

Guerra C, Koza RA, Yamashita H, Walsh K, Kozak LP.

J Clin Invest. 1998 Jul 15;102(2):412-20.PMID: 9664083 [PubMed - indexed for MEDLINE]Related articlesFree article

Cig30, a mouse member of a novel membrane protein gene family, is involved in the recruitment of brown adipose tissue.

Tvrdik P, Asadi A, Kozak LP, Nedergaard J, Cannon B, Jacobsson A.

J Biol Chem. 1997 Dec 12;272(50):31738-46.PMID: 9395518 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic mapping of the C-type natriuretic peptide receptor (Npr2) gene to mouse chromosome 4.

Nuglozeh E, Kozak LP.

Mamm Genome. 1997 Aug;8(8):624-5. No abstract available. PMID: 9250880 [PubMed - indexed for MEDLINE]Related articles

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese.

Enerbäck S, Jacobsson A, Simpson EM, Guerra C, Yamashita H, Harper ME, Kozak LP.

Nature. 1997 May 1;387(6628):90-4.PMID: 9139827 [PubMed - indexed for MEDLINE]Related articles

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein.

Ackerman SL, Kozak LP, Przyborski SA, Rund LA, Boyer BB, Knowles BB.

Nature. 1997 Apr 24;386(6627):838-42.PMID: 9126743 [PubMed - indexed for MEDLINE]Related articles

Sequence and tissue-dependent RNA expression of mouse FAD-linked glycerol-3-phosphate dehydrogenase.

Koza RA, Kozak UC, Brown LJ, Leiter EH, MacDonald MJ, Kozak LP.

Arch Biochem Biophys. 1996 Dec 1;336(1):97-104.PMID: 8951039 [PubMed - indexed for MEDLINE]Related articles

Reduction of dietary obesity in aP2-Ucp transgenic mice: physiology and adipose tissue distribution.

Kopecký J, Hodný Z, Rossmeisl M, Syrový I, Kozak LP.

Am J Physiol. 1996 May;270(5 Pt 1):E768-75.PMID: 8967464 [PubMed - indexed for MEDLINE]Related articles

Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity.

Kopecky J, Clarke G, Enerbäck S, Spiegelman B, Kozak LP.

J Clin Invest. 1995 Dec;96(6):2914-23.PMID: 8675663 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines.

Rohlfs EM, Daniel KW, Premont RT, Kozak LP, Collins S.

J Biol Chem. 1995 May 5;270(18):10723-32.PMID: 7738011 [PubMed - indexed for MEDLINE]Related articlesFree article

Norepinephrine-dependent selection of brown adipocyte cell lines.

Kozak UC, Kozak LP.

Endocrinology. 1994 Feb;134(2):906-13.PMID: 7905411 [PubMed - indexed for MEDLINE]Related articles

An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene.

Kozak UC, Kopecky J, Teisinger J, Enerbäck S, Boyer B, Kozak LP.

Mol Cell Biol. 1994 Jan;14(1):59-67.PMID: 8264627 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue.

Lowell BB, S-Susulic V, Hamann A, Lawitts JA, Himms-Hagen J, Boyer BB, Kozak LP, Flier JS.

Nature. 1993 Dec 23-30;366(6457):740-2.PMID: 8264795 [PubMed - indexed for MEDLINE]Related articles

Adrenergic regulation of the mitochondrial uncoupling protein gene in brown fat tumor cells.

Kozak UC, Held W, Kreutter D, Kozak LP.

Mol Endocrinol. 1992 May;6(5):763-72.PMID: 1603085 [PubMed - indexed for MEDLINE]Related articles