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Glyceraldehyde 3 phosphate dehydrogenase in retinal microvasculature: Implications for the development and progression of diabetic retinopathy.

Madsen-Bouterse S, Mohammad G, Kowluru RA.

Invest Ophthalmol Vis Sci. 2009 Oct 29. [Epub ahead of print]PMID: 19875652 [PubMed - as supplied by publisher]Related articles

Translocation of H-Ras and its implications in the development of diabetic retinopathy.

Kowluru RA, Kanwar M.

Biochem Biophys Res Commun. 2009 Sep 25;387(3):461-6. Epub 2009 Jul 14.PMID: 19607814 [PubMed - indexed for MEDLINE]Related articles

Metabolic memory in diabetes - from in vitro oddity to in vivo problem: Role of Apoptosis.

Kowluru RA, Chan PS.

Brain Res Bull. 2009 May 20. [Epub ahead of print]PMID: 19463916 [PubMed - as supplied by publisher]Related articles

Oxidative stress and the development of diabetic retinopathy: contributory role of matrix metalloproteinase-2.

Kowluru RA, Kanwar M.

Free Radic Biol Med. 2009 Jun 15;46(12):1677-85. Epub 2009 Apr 5.PMID: 19345729 [PubMed - indexed for MEDLINE]Related articles

Resistance of retinal inflammatory mediators to suppress after reinstitution of good glycemic control: novel mechanism for metabolic memory.

Chan PS, Kanwar M, Kowluru RA.

J Diabetes Complications. 2008 Dec 2. [Epub ahead of print]PMID: 19056300 [PubMed - as supplied by publisher]Related articles

Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy.

Kanwar M, Kowluru RA.

Diabetes. 2009 Jan;58(1):227-34. Epub 2008 Oct 13.PMID: 18852331 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of retinopathy and retinal metabolic abnormalities in diabetic rats with AREDS-based micronutrients.

Kowluru RA, Kanwar M, Chan PS, Zhang JP.

Arch Ophthalmol. 2008 Sep;126(9):1266-72.PMID: 18779489 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives.

Madsen-Bouterse SA, Kowluru RA.

Rev Endocr Metab Disord. 2008 Dec;9(4):315-27. Review.PMID: 18654858 [PubMed - indexed for MEDLINE]Related articles

Diabetes regulates small molecular weight G-protein, H-Ras, in the microvasculature of the retina: implication in the development of retinopathy.

Kanwar M, Kowluru RA.

Microvasc Res. 2008 Nov;76(3):189-93. Epub 2008 Apr 25.PMID: 18514235 [PubMed - indexed for MEDLINE]Related articlesFree article

Beneficial effect of zeaxanthin on retinal metabolic abnormalities in diabetic rats.

Kowluru RA, Menon B, Gierhart DL.

Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1645-51.PMID: 18385086 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase.

Kanwar M, Chan PS, Kern TS, Kowluru RA.

Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3805-11.PMID: 17652755 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress and diabetic retinopathy.

Kowluru RA, Chan PS.

Exp Diabetes Res. 2007;2007:43603. Review.PMID: 17641741 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries.

Kowluru RA, Kanwar M, Kennedy A.

Exp Diabetes Res. 2007;2007:21976.PMID: 17641740 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased oxidative stress in diabetes regulates activation of a small molecular weight G-protein, H-Ras, in the retina.

Kowluru V, Kowluru RA.

Mol Vis. 2007 Apr 19;13:602-10.PMID: 17515880 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of curcumin on retinal oxidative stress and inflammation in diabetes.

Kowluru RA, Kanwar M.

Nutr Metab (Lond). 2007 Apr 16;4:8.PMID: 17437639 [PubMed]Related articlesFree article

Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress.

Kowluru RA, Kowluru V, Xiong Y, Ho YS.

Free Radic Biol Med. 2006 Oct 15;41(8):1191-6. Epub 2006 Feb 6.PMID: 17015165 [PubMed - indexed for MEDLINE]Related articles

Small molecular weight G-protein, H-Ras, and retinal endothelial cell apoptosis in diabetes.

Kowluru RA, Kowluru A, Kanwar M.

Mol Cell Biochem. 2007 Feb;296(1-2):69-76. Epub 2006 Aug 19.PMID: 16924412 [PubMed - indexed for MEDLINE]Related articles

Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy.

Kowluru RA, Atasi L, Ho YS.

Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1594-9.PMID: 16565397 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death.

Kowluru RA.

Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1581-87. Review.PMID: 16356121 [PubMed - indexed for MEDLINE]Related articles

Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kappaB) in the retina.

Kowluru RA, Chakrabarti S, Chen S.

Acta Diabetol. 2004 Dec;41(4):194-9.PMID: 15660203 [PubMed - indexed for MEDLINE]Related articles

Effect of advanced glycation end products on accelerated apoptosis of retinal capillary cells under in vitro conditions.

Kowluru RA.

Life Sci. 2005 Jan 14;76(9):1051-60.PMID: 15607333 [PubMed - indexed for MEDLINE]Related articles

Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats.

Kowluru RA, Odenbach S.

Diabetes. 2004 Dec;53(12):3233-8.PMID: 15561955 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of interleukin-1beta in the development of retinopathy in rats: effect of antioxidants.

Kowluru RA, Odenbach S.

Invest Ophthalmol Vis Sci. 2004 Nov;45(11):4161-6.PMID: 15505070 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of interleukin-1beta in the pathogenesis of diabetic retinopathy.

Kowluru RA, Odenbach S.

Br J Ophthalmol. 2004 Oct;88(10):1343-7.PMID: 15377563 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of hyperglycemia and diabetic nephropathy: effect of reinstitution of good metabolic control on oxidative stress in the kidney of diabetic rats.

Kowluru RA, Abbas SN, Odenbach S.

J Diabetes Complications. 2004 Sep-Oct;18(5):282-8.PMID: 15337502 [PubMed - indexed for MEDLINE]Related articles

Potential contributory role of H-Ras, a small G-protein, in the development of retinopathy in diabetic rats.

Kowluru RA, Kowluru A, Chakrabarti S, Khan Z.

Diabetes. 2004 Mar;53(3):775-83.PMID: 14988264 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants.

Kowluru RA, Koppolu P, Chakrabarti S, Chen S.

Free Radic Res. 2003 Nov;37(11):1169-80.PMID: 14703729 [PubMed - indexed for MEDLINE]Related articles

Diabetes-induced mitochondrial dysfunction in the retina.

Kowluru RA, Abbas SN.

Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5327-34.PMID: 14638734 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats.

Kowluru RA.

Diabetes. 2003 Mar;52(3):818-23.PMID: 12606525 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-induced activation of caspase-3 in retina: effect of antioxidant therapy.

Kowluru RA, Koppolu P.

Free Radic Res. 2002 Sep;36(9):993-9.PMID: 12448825 [PubMed - indexed for MEDLINE]Related articles

Termination of experimental galactosemia in rats, and progression of retinal metabolic abnormalities.

Kowluru RA, Koppolu P.

Invest Ophthalmol Vis Sci. 2002 Oct;43(10):3287-91.PMID: 12356836 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal metabolic abnormalities in diabetic mouse: comparison with diabetic rat.

Kowluru RA.

Curr Eye Res. 2002 Feb;24(2):123-8.PMID: 12187484 [PubMed - indexed for MEDLINE]Related articles

Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are interrelated.

Kowluru RA.

Acta Diabetol. 2001 Dec;38(4):179-85.PMID: 11855796 [PubMed - indexed for MEDLINE]Related articles

Therapeutic potential of anti-oxidants and diabetic retinopathy.

Kowluru RA, Kennedy A.

Expert Opin Investig Drugs. 2001 Sep;10(9):1665-76. Review.PMID: 11772276 [PubMed - indexed for MEDLINE]Related articles

Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy.

Kowluru RA, Tang J, Kern TS.

Diabetes. 2001 Aug;50(8):1938-42.PMID: 11473058 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal glutamate in diabetes and effect of antioxidants.

Kowluru RA, Engerman RL, Case GL, Kern TS.

Neurochem Int. 2001 Apr;38(5):385-90.PMID: 11222918 [PubMed - indexed for MEDLINE]Related articles

Abnormalities of retinal metabolism in diabetes or experimental galactosemia VIII. Prevention by aminoguanidine.

Kowluru RA, Engerman RL, Kern TS.

Curr Eye Res. 2000 Oct;21(4):814-9.PMID: 11120572 [PubMed - indexed for MEDLINE]Related articles

Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia.

Kern TS, Tang J, Mizutani M, Kowluru RA, Nagaraj RH, Romeo G, Podesta F, Lorenzi M.

Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3972-8.PMID: 11053301 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-induced metabolic abnormalities in myocardium: effect of antioxidant therapy.

Kowluru RA, Engerman RL, Kern TS.

Free Radic Res. 2000 Jan;32(1):67-74.PMID: 10625218 [PubMed - indexed for MEDLINE]Related articles

Subnormal retinal oxygenation response precedes diabetic-like retinopathy.

Berkowitz BA, Kowluru RA, Frank RN, Kern TS, Hohman TC, Prakash M.

Invest Ophthalmol Vis Sci. 1999 Aug;40(9):2100-5.PMID: 10440266 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormalities of retinal metabolism in diabetes or experimental galactosemia. VI. Comparison of retinal and cerebral cortex metabolism, and effects of antioxidant therapy.

Kowluru RA, Engerman RL, Kern TS.

Free Radic Biol Med. 1999 Feb;26(3-4):371-8.PMID: 9895229 [PubMed - indexed for MEDLINE]Related articles

Subcellular localization and characterization of nucleoside diphosphate kinase in rat retina: effect of diabetes.

Kowluru A, Kowluru RA.

Biosci Rep. 1998 Aug;18(4):187-98.PMID: 9877232 [PubMed - indexed for MEDLINE]Related articles

Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases.

Kowluru RA, Jirousek MR, Stramm L, Farid N, Engerman RL, Kern TS.

Diabetes. 1998 Mar;47(3):464-9.PMID: 9519755 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormalities of retinal metabolism in diabetes or experimental galactosemia. IV. Antioxidant defense system.

Kowluru RA, Kern TS, Engerman RL.

Free Radic Biol Med. 1997;22(4):587-92.PMID: 9013121 [PubMed - indexed for MEDLINE]Related articles

Abnormalities of retinal metabolism in diabetes or experimental galactosemia. III. Effects of antioxidants.

Kowluru RA, Kern TS, Engerman RL, Armstrong D.

Diabetes. 1996 Sep;45(9):1233-7.PMID: 8772728 [PubMed - indexed for MEDLINE]Related articles

Abnormalities of retinal metabolism in diabetes or galactosemia: ATPases and glutathione.

Kern TS, Kowluru RA, Engerman RL.

Invest Ophthalmol Vis Sci. 1994 Jun;35(7):2962-7.PMID: 8206713 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional alterations of G-proteins in diabetic rat retina: a possible explanation for the early visual abnormalities in diabetes mellitus.

Kowluru A, Kowluru RA, Yamazaki A.

Diabetologia. 1992 Jul;35(7):624-31.PMID: 1322850 [PubMed - indexed for MEDLINE]Related articles

Phospholipid N-methylation in diabetic erythrocytes: effects on membrane Na+, K+ ATPase activity.

Kowluru A, Kowluru RA.

Cell Biochem Funct. 1992 Jun;10(2):95-101.PMID: 1321009 [PubMed - indexed for MEDLINE]Related articles

Preferential excretion of glycated albumin in C57BL-Ks-J mice: effects of diabetes.

Kowluru A, Kowluru RA.

Experientia. 1992 May 15;48(5):486-8.PMID: 1601114 [PubMed - indexed for MEDLINE]Related articles

Erythrocyte sodium-potassium ATPase activity and thiol metabolism in genetically hyperglycemic mice.

Kowluru RA, Kowluru A.

Metabolism. 1992 Feb;41(2):160-4.PMID: 1310517 [PubMed - indexed for MEDLINE]Related articles