PubMed

A pilot study to assess the feasibility of a multicenter cluster randomized trial for the management of asymptomatic persons with a thrombophilia.

Wells PS, Louzada ML, Taljaard M, Anderson DR, Kahn SR, Langlois NJ, Rutberg J, Kovacs MJ, Rodger MA.

J Genet Couns. 2009 Oct;18(5):475-82. Epub 2009 Jun 3.PMID: 19495945 [PubMed - in process]Related articles

Predicting warfarin maintenance dose in patients with venous thromboembolism based on the response to a standardized warfarin initiation nomogram.

Lazo-Langner A, Monkman K, Kovacs MJ.

J Thromb Haemost. 2009 Aug;7(8):1276-83. Epub 2009 May 12.PMID: 19453939 [PubMed - in process]Related articles

Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial.

Crowther MA, Ageno W, Garcia D, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Vesely SK, Schulman S, Kovacs MJ, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MB, Kearon C.

Ann Intern Med. 2009 Mar 3;150(5):293-300.PMID: 19258557 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of a diagnostic approach to exclude recurrent venous thromboembolism.

Le Gal G, Kovacs MJ, Carrier M, Do K, Kahn SR, Wells PS, Anderson DA, Chagnon I, Solymoss S, Crowther M, Righini M, Perrier A, White RH, Vickars L, Rodger M.

J Thromb Haemost. 2009 May;7(5):752-9. Epub 2009 Feb 18.PMID: 19228281 [PubMed - indexed for MEDLINE]Related articles

A 10 mg warfarin initiation nomogram is safe and effective in outpatients starting oral anticoagulant therapy for venous thromboembolism.

Monkman K, Lazo-Langner A, Kovacs MJ.

Thromb Res. 2009 Jul;124(3):275-80. Epub 2009 Jan 19.PMID: 19155056 [PubMed - indexed for MEDLINE]Related articles

MGUS: not so benign after all.

Kovacs MJ.

Blood. 2008 Nov 1;112(9):3533. No abstract available. PMID: 18948581 [PubMed]Related articlesFree article

Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trial.

Kearon C, Julian JA, Kovacs MJ, Anderson DR, Wells P, Mackinnon B, Weitz JI, Crowther MA, Dolan S, Turpie AG, Geerts W, Solymoss S, van Nguyen P, Demers C, Kahn SR, Kassis J, Rodger M, Hambleton J, Gent M, Ginsberg JS; ELATE Investigators.

Blood. 2008 Dec 1;112(12):4432-6. Epub 2008 Sep 12.PMID: 18791166 [PubMed - indexed for MEDLINE]Related articles

Identifying unprovoked thromboembolism patients at low risk for recurrence who can discontinue anticoagulant therapy.

Rodger MA, Kahn SR, Wells PS, Anderson DA, Chagnon I, Le Gal G, Solymoss S, Crowther M, Perrier A, White R, Vickars L, Ramsay T, Betancourt MT, Kovacs MJ.

CMAJ. 2008 Aug 26;179(5):417-26.PMID: 18725614 [PubMed - indexed for MEDLINE]Related articlesFree article

Inter-observer reliability of measures to assess the post-thrombotic syndrome.

Rodger MA, Kahn SR, Le Gal G, Solymoss S, Chagnon I, Anderson DR, Wells PS, Kovacs MJ.

Thromb Haemost. 2008 Jul;100(1):164-6. No abstract available. PMID: 18612557 [PubMed - indexed for MEDLINE]Related articles

Treatment of relapsed and refractory myeloma.

Reece DE, Leitch HA, Atkins H, Voralia M, Canning LA, LeBlanc R, Belch AR, White D, Kovacs MJ.

Leuk Lymphoma. 2008 Aug;49(8):1470-85. Review.PMID: 18608859 [PubMed - indexed for MEDLINE]Related articles

Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial.

Anderson DR, Kahn SR, Rodger MA, Kovacs MJ, Morris T, Hirsch A, Lang E, Stiell I, Kovacs G, Dreyer J, Dennie C, Cartier Y, Barnes D, Burton E, Pleasance S, Skedgel C, O'Rouke K, Wells PS.

JAMA. 2007 Dec 19;298(23):2743-53.PMID: 18165667 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased mortality in hemodialysis patients having specific antibodies to the platelet factor 4-heparin complex.

Carrier M, Rodger MA, Fergusson D, Doucette S, Kovacs MJ, Moore J, Kelton JG, Knoll GA.

Kidney Int. 2008 Jan;73(2):213-9. Epub 2007 Oct 17.PMID: 17943076 [PubMed - indexed for MEDLINE]Related articles

Effectiveness of compression stockings to prevent the post-thrombotic syndrome (the SOX Trial and Bio-SOX biomarker substudy): a randomized controlled trial.

Kahn SR, Shbaklo H, Shapiro S, Wells PS, Kovacs MJ, Rodger MA, Anderson DR, Ginsberg JS, Johri M, Tagalakis V; SOX Trial Investigators.

BMC Cardiovasc Disord. 2007 Jul 24;7:21.PMID: 17711595 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term dalteparin in pregnancy not associated with a decrease in bone mineral density: substudy of a randomized controlled trial.

Rodger MA, Kahn SR, Cranney A, Hodsman A, Kovacs MJ, Clement AM, Lazo-Langner A, Hague WM; TIPPS investigators.

J Thromb Haemost. 2007 Aug;5(8):1600-6.PMID: 17663731 [PubMed - indexed for MEDLINE]Related articles

The effect of dalteparin on coagulation activation during pregnancy in women with thrombophilia. A randomized trial.

Abou-Nassar K, Kovacs MJ, Kahn SR, Wells P, Doucette S, Ramsay T, Clement AM, Khurana R, Mackinnon K, Blostein M, Solymoss S, Kingdom J, Sermer M, Rey E, Rodger M; TIPPS investigators.

Thromb Haemost. 2007 Jul;98(1):163-71.PMID: 17598009 [PubMed - indexed for MEDLINE]Related articles

A pilot study of central venous catheter survival in cancer patients using low-molecular-weight heparin (dalteparin) and warfarin without catheter removal for the treatment of upper extremity deep vein thrombosis (The Catheter Study).

Kovacs MJ, Kahn SR, Rodger M, Anderson DR, Andreou R, Mangel JE, Morrow B, Clement AM, Wells PS.

J Thromb Haemost. 2007 Aug;5(8):1650-3. Epub 2007 May 7.PMID: 17488349 [PubMed - indexed for MEDLINE]Related articles

Frequency of renal impairment, advanced age, obesity and cancer in venous thromboembolism patients in clinical practice.

Cook LM, Kahn SR, Goodwin J, Kovacs MJ.

J Thromb Haemost. 2007 May;5(5):937-41. Erratum in: J Thromb Haemost. 2007 Aug;5(8):1791. PMID: 17461927 [PubMed - indexed for MEDLINE]Related articles

A randomised comparison of melphalan with prednisone or dexamethasone as induction therapy and dexamethasone or observation as maintenance therapy in multiple myeloma: NCIC CTG MY.7.

Shustik C, Belch A, Robinson S, Rubin SH, Dolan SP, Kovacs MJ, Grewal KS, Walde D, Barr R, Wilson J, Gill K, Vickars L, Rudinskas L, Sicheri DA, Wilson K, Djurfeldt M, Shepherd LE, Ding K, Meyer RM.

Br J Haematol. 2007 Jan;136(2):203-11.PMID: 17233817 [PubMed - indexed for MEDLINE]Related articles

The prevalence of antibodies to the platelet factor 4 -heparin complex and association with access thrombosis in patients on chronic hemodialysis.

Carrier M, Knoll GA, Kovacs MJ, Moore JC, Fergusson D, Rodger MA.

Thromb Res. 2007;120(2):215-20. Epub 2006 Nov 13.PMID: 17098277 [PubMed - indexed for MEDLINE]Related articles

A phase II study of ZD6474 (Zactima, a selective inhibitor of VEGFR and EGFR tyrosine kinase in patients with relapsed multiple myeloma--NCIC CTG IND.145.

Kovacs MJ, Reece DE, Marcellus D, Meyer RM, Mathews S, Dong RP, Eisenhauer E.

Invest New Drugs. 2006 Nov;24(6):529-35.PMID: 16791411 [PubMed - indexed for MEDLINE]Related articles

An evaluation of D-dimer in the diagnosis of pulmonary embolism: a randomized trial.

Kearon C, Ginsberg JS, Douketis J, Turpie AG, Bates SM, Lee AY, Crowther MA, Weitz JI, Brill-Edwards P, Wells P, Anderson DR, Kovacs MJ, Linkins LA, Julian JA, Bonilla LR, Gent M; Canadian Pulmonary Embolism Diagnosis Study (CANPEDS) Group.

Ann Intern Med. 2006 Jun 6;144(11):812-21.PMID: 16754923 [PubMed - indexed for MEDLINE]Related articlesFree article

Standard-intensity vs low-dose anticoagulation for long-term management of patients with venous thromboembolism.

Lazo-Langner A, Kovacs MJ.

Clin Adv Hematol Oncol. 2005 Nov;3(11):877-9. Review. No abstract available. PMID: 16491633 [PubMed - indexed for MEDLINE]Related articles

The standard is still the standard or why an INR of 2-3 is still the optimal intensity for secondary prevention of venous thromboembolism.

Kovacs MJ.

J Thromb Thrombolysis. 2006 Feb;21(1):53-6.PMID: 16475043 [PubMed - indexed for MEDLINE]Related articles

Protein C and protein S levels can be accurately determined within 24 hours of diagnosis of acute venous thromboembolism.

Kovacs MJ, Kovacs J, Anderson J, Rodger MA, Mackinnon K, Wells PS.

Clin Lab Haematol. 2006 Feb;28(1):9-13.PMID: 16430453 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of spiral computed tomography contrast angiography and ultrasonography to exclude the diagnosis of pulmonary embolism in the emergency department.

Anderson DR, Kovacs MJ, Dennie C, Kovacs G, Stiell I, Dreyer J, McCarron B, Pleasance S, Burton E, Cartier Y, Wells PS.

J Emerg Med. 2005 Nov;29(4):399-404.PMID: 16243195 [PubMed - indexed for MEDLINE]Related articles

Fondaparinux: a potential new therapy for HIT.

Kuo KH, Kovacs MJ.

Hematology. 2005 Aug;10(4):271-5. Review.PMID: 16085538 [PubMed - indexed for MEDLINE]Related articles

Deep vein thrombosis.

Kearon C, Kovacs MJ, Julian JA.

Lancet. 2005 Jul 9-15;366(9480):118; author reply 119-20. No abstract available. PMID: 16005325 [PubMed - indexed for MEDLINE]Related articles

Anti-Xa effect of a low molecular weight heparin (dalteparin) does not accumulate in extended duration therapy for venous thromboembolism in cancer patients.

Kovacs MJ, Levine MN, Keeney M, Mackinnon KM, Lee AY.

Thromb Haemost. 2005 Jun;93(6):1185-8.PMID: 15968406 [PubMed - indexed for MEDLINE]Related articles

Successful treatment of heparin induced thrombocytopenia (HIT) with fondaparinux.

Kovacs MJ.

Thromb Haemost. 2005 May;93(5):999-1000. No abstract available. PMID: 15886823 [PubMed - indexed for MEDLINE]Related articles

Does the type of hormone replacement therapy influence the risk of deep vein thrombosis? A prospective case-control study.

Douketis JD, Julian JA, Kearon C, Anderson DR, Crowther MA, Bates SM, Barone M, Piovella F, Turpie AG, Middeldorp S, van Nguyen P, Prandoni P, Wells PS, Kovacs MJ, MacGillavry MR, Costantini L, Ginsberg JS.

J Thromb Haemost. 2005 May;3(5):943-8.PMID: 15869589 [PubMed - indexed for MEDLINE]Related articles

A randomized trial comparing 2 low-molecular-weight heparins for the outpatient treatment of deep vein thrombosis and pulmonary embolism.

Wells PS, Anderson DR, Rodger MA, Forgie MA, Florack P, Touchie D, Morrow B, Gray L, O'Rourke K, Wells G, Kovacs J, Kovacs MJ.

Arch Intern Med. 2005 Apr 11;165(7):733-8.PMID: 15824291 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of warfarin on symptoms of fatigue: findings of a randomized trial.

Kovacs MJ, Kearon C, Julian JA, Douketis JD, Demers C, Wells PS, Turpie AG, Anderson DR, Kahn SR, Nguyen PV, Green D, Kassis J, Geerts W, Mackinnon B, Ginsberg JS.

Ann Pharmacother. 2005 May;39(5):840-2. Epub 2005 Mar 15.PMID: 15769830 [PubMed - indexed for MEDLINE]Related articles

Predictors of the post-thrombotic syndrome during long-term treatment of proximal deep vein thrombosis.

Kahn SR, Kearon C, Julian JA, Mackinnon B, Kovacs MJ, Wells P, Crowther MA, Anderson DR, Van Nguyen P, Demers C, Solymoss S, Kassis J, Geerts W, Rodger M, Hambleton J, Ginsberg JS; Extended Low-intensity Anticoagulation for Thrombo-embolism (ELATE) Investigators.

J Thromb Haemost. 2005 Apr;3(4):718-23. Epub 2005 Feb 23.PMID: 15733061 [PubMed - indexed for MEDLINE]Related articles

The safety of dosing dalteparin based on actual body weight for the treatment of acute venous thromboembolism in obese patients.

Al-Yaseen E, Wells PS, Anderson J, Martin J, Kovacs MJ.

J Thromb Haemost. 2005 Jan;3(1):100-2.PMID: 15634272 [PubMed - indexed for MEDLINE]Related articles

Results of a multicenter randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant.

Stewart AK, Chen CI, Howson-Jan K, White D, Roy J, Kovacs MJ, Shustik C, Sadura A, Shepherd L, Ding K, Meyer RM, Belch AR.

Clin Cancer Res. 2004 Dec 15;10(24):8170-6.PMID: 15623591 [PubMed - indexed for MEDLINE]Related articlesFree article

Single-arm study of bridging therapy with low-molecular-weight heparin for patients at risk of arterial embolism who require temporary interruption of warfarin.

Kovacs MJ, Kearon C, Rodger M, Anderson DR, Turpie AG, Bates SM, Desjardins L, Douketis J, Kahn SR, Solymoss S, Wells PS.

Circulation. 2004 Sep 21;110(12):1658-63. Epub 2004 Sep 13.PMID: 15364803 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term low-dose warfarin use is effective in the prevention of recurrent venous thromboembolism: no.

Kovacs MJ.

J Thromb Haemost. 2004 Jul;2(7):1041-3. No abstract available. PMID: 15219183 [PubMed - indexed for MEDLINE]Related articles

Imatinib mesylate treatment in two patients with idiopathic hypereosinophilic syndrome.

Payne SM, Kovacs MJ.

Ann Pharmacother. 2004 Jul-Aug;38(7-8):1215-8. Epub 2004 Jun 8.PMID: 15187212 [PubMed - indexed for MEDLINE]Related articles

D-dimer levels < 250 ng/mL after oral anticoagulation predicted a low risk for recurrent venous thromboembolism.

Kovacs MJ.

ACP J Club. 2004 Mar-Apr;140(2):50. No abstract available. PMID: 15122870 [PubMed]Related articles

Comparison of 1 month with 3 months of anticoagulation for a first episode of venous thromboembolism associated with a transient risk factor.

Kearon C, Ginsberg JS, Anderson DR, Kovacs MJ, Wells P, Julian JA, Mackinnon B, Demers C, Douketis J, Turpie AG, Van Nguyen P, Green D, Kassis J, Kahn SR, Solymoss S, Desjardins L, Geerts W, Johnston M, Weitz JI, Hirsh J, Gent M; SOFAST Investigators.

J Thromb Haemost. 2004 May;2(5):743-9.PMID: 15099280 [PubMed - indexed for MEDLINE]Related articles

Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis.

Wells PS, Anderson DR, Rodger M, Forgie M, Kearon C, Dreyer J, Kovacs G, Mitchell M, Lewandowski B, Kovacs MJ.

N Engl J Med. 2003 Sep 25;349(13):1227-35.PMID: 14507948 [PubMed - indexed for MEDLINE]Related articlesFree article

A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome.

Crowther MA, Ginsberg JS, Julian J, Denburg J, Hirsh J, Douketis J, Laskin C, Fortin P, Anderson D, Kearon C, Clarke A, Geerts W, Forgie M, Green D, Costantini L, Yacura W, Wilson S, Gent M, Kovacs MJ.

N Engl J Med. 2003 Sep 18;349(12):1133-8. Erratum in: N Engl J Med. 2003 Dec 25;349(26):2577. N Engl J Med. 2004 Jul 8;351(2):200. PMID: 13679527 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of 3.2 vs. 3.8% sodium citrate concentration on anti-Xa levels for patients on therapeutic low molecular weight heparin.

Payne S, MacKinnon K, Keeney M, Morrow B, Kovacs MJ.

Clin Lab Haematol. 2003 Oct;25(5):317-9.PMID: 12974723 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparing the quality of oral anticoagulant management by anticoagulation clinics and by family physicians: a randomized controlled trial.

Wilson SJ, Wells PS, Kovacs MJ, Lewis GM, Martin J, Burton E, Anderson DR.

CMAJ. 2003 Aug 19;169(4):293-8. Erratum in: CMAJ. 2004 Feb 17;170(4):451. PMID: 12925422 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism.

Kearon C, Ginsberg JS, Kovacs MJ, Anderson DR, Wells P, Julian JA, MacKinnon B, Weitz JI, Crowther MA, Dolan S, Turpie AG, Geerts W, Solymoss S, van Nguyen P, Demers C, Kahn SR, Kassis J, Rodger M, Hambleton J, Gent M; Extended Low-Intensity Anticoagulation for Thrombo-Embolism Investigators.

N Engl J Med. 2003 Aug 14;349(7):631-9.PMID: 12917299 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined use of clinical assessment and d-dimer to improve the management of patients presenting to the emergency department with suspected deep vein thrombosis (the EDITED Study).

Anderson DR, Kovacs MJ, Kovacs G, Stiell I, Mitchell M, Khoury V, Dryer J, Ward J, Wells PS.

J Thromb Haemost. 2003 Apr;1(4):645-51.PMID: 12871396 [PubMed - indexed for MEDLINE]Related articles

Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer.

Lee AY, Levine MN, Baker RI, Bowden C, Kakkar AK, Prins M, Rickles FR, Julian JA, Haley S, Kovacs MJ, Gent M; Randomized Comparison of Low-Molecular-Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer (CLOT) Investigators.

N Engl J Med. 2003 Jul 10;349(2):146-53.PMID: 12853587 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of 10-mg and 5-mg warfarin initiation nomograms together with low-molecular-weight heparin for outpatient treatment of acute venous thromboembolism. A randomized, double-blind, controlled trial.

Kovacs MJ, Rodger M, Anderson DR, Morrow B, Kells G, Kovacs J, Boyle E, Wells PS.

Ann Intern Med. 2003 May 6;138(9):714-9.PMID: 12729425 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoimmune thrombocytopenia due to chronic lymphocytic leukemia treated with fludarabine.

Wells T, Kovacs MJ.

Ann Pharmacother. 2003 May;37(5):671-4.PMID: 12708944 [PubMed - indexed for MEDLINE]Related articles

Cutaneous dalteparin reactions associated with antibodies of heparin-induced thrombocytopenia.

Payne SM, Kovacs MJ.

Ann Pharmacother. 2003 May;37(5):655-8.PMID: 12708940 [PubMed - indexed for MEDLINE]Related articles