PubMed

Restriction fragment length polymorphism typing demonstrates substantial diversity among Pneumocystis jirovecii isolates.

Ripamonti C, Orenstein A, Kutty G, Huang L, Schuhegger R, Sing A, Fantoni G, Atzori C, Vinton C, Huber C, Conville PS, Kovacs JA.

J Infect Dis. 2009 Nov 15;200(10):1616-22.PMID: 19795979 [PubMed - indexed for MEDLINE]Related articles

Gemfibrozil Concentrations Are Significantly Decreased in the Presence of Lopinavir-Ritonavir.

Busse KH, Hadigan C, Chairez C, Alfaro RM, Formentini E, Kovacs JA, Penzak SR.

J Acquir Immune Defic Syndr. 2009 Jul 30. [Epub ahead of print]PMID: 19648824 [PubMed - as supplied by publisher]Related articles

Interleukin-2 cycling causes transient increases in high-sensitivity C-reactive protein and D-dimer that are not associated with plasma HIV-RNA levels.

Porter BO, Shen J, Kovacs JA, Davey RT, Rehm C, Lozier J, Csako G, Nghiem K, Costello R, Lane HC, Sereti I.

AIDS. 2009 Sep 24;23(15):2015-9.PMID: 19617815 [PubMed - in process]Related articles

Evolving health effects of Pneumocystis: one hundred years of progress in diagnosis and treatment.

Kovacs JA, Masur H.

JAMA. 2009 Jun 24;301(24):2578-85.PMID: 19549975 [PubMed - indexed for MEDLINE]Related articles

High sensitivity and specificity of acid-fast microscopy for diagnosis of pulmonary tuberculosis in an African population with a high prevalence of human immunodeficiency virus.

Shea YR, Davis JL, Huang L, Kovacs JA, Masur H, Mulindwa F, Opus S, Chow Y, Murray PR.

J Clin Microbiol. 2009 May;47(5):1553-5. Epub 2009 Mar 18.PMID: 19297594 [PubMed - indexed for MEDLINE]Related articlesFree article

Four-antigen mixture containing v-cyclin for serological screening of human herpesvirus 8 infection.

Burbelo PD, Leahy HP, Groot S, Bishop LR, Miley W, Iadarola MJ, Whitby D, Kovacs JA.

Clin Vaccine Immunol. 2009 May;16(5):621-7. Epub 2009 Mar 4.PMID: 19261774 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymerase chain reaction of secA1 on sputum or oral wash samples for the diagnosis of pulmonary tuberculosis.

Davis JL, Huang L, Kovacs JA, Masur H, Murray P, Havlir DV, Worodria WO, Charlebois ED, Srikantiah P, Cattamanchi A, Huber C, Shea YR, Chow Y, Fischer SH.

Clin Infect Dis. 2009 Mar 15;48(6):725-32.PMID: 19207077 [PubMed - indexed for MEDLINE]Related articles

Inferiority of IL-2 alone versus IL-2 with HAART in maintaining CD4 T cell counts during HAART interruption: a randomized controlled trial.

Porter BO, Anthony KB, Shen J, Hahn B, Keh CE, Maldarelli F, Blackwelder WC, Lane HC, Kovacs JA, Davey RT, Sereti I.

AIDS. 2009 Jan 14;23(2):203-12.PMID: 19098490 [PubMed - indexed for MEDLINE]Related articles

Properties of square-pyramidal alkyl-thiolate Fe(III) complexes, including an analogue of the unmodified form of nitrile hydratase.

Lugo-Mas P, Taylor W, Schweitzer D, Theisen RM, Xu L, Shearer J, Swartz RD, Gleaves MC, Dipasquale A, Kaminsky W, Kovacs JA.

Inorg Chem. 2008 Dec 1;47(23):11228-36.PMID: 18989922 [PubMed - indexed for MEDLINE]Related articles

CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients.

Read SW, Lempicki RA, Di Mascio M, Srinivasula S, Burke R, Sachau W, Bosche M, Adelsberger JW, Sereti I, Davey RT Jr, Tavel JA, Huang CY, Issaq HJ, Fox SD, Lane HC, Kovacs JA.

J Infect Dis. 2008 Sep 15;198(6):843-50.PMID: 18684102 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of antiretroviral drugs on the pharmacokinetics of prednisolone in HIV-infected individuals.

Busse KH, Formentini E, Alfaro RM, Kovacs JA, Penzak SR.

J Acquir Immune Defic Syndr. 2008 Aug 15;48(5):561-6.PMID: 18645517 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the major surface glycoprotein genes in Pneumocystis jirovecii.

Kutty G, Maldarelli F, Achaz G, Kovacs JA.

J Infect Dis. 2008 Sep 1;198(5):741-9.PMID: 18627244 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of continuous versus pericycle antiretroviral therapy on IL-2 responsiveness.

Healey LM, Hahn BK, Rehm CA, Adelsberger J, Qin J, Follmann DA, Tavel J, Kovacs JA, Sereti I, Davey RT Jr.

J Interferon Cytokine Res. 2008 Jul;28(7):455-62.PMID: 18597618 [PubMed - indexed for MEDLINE]Related articlesFree article

Damped-dynamics flexible fitting.

Kovacs JA, Yeager M, Abagyan R.

Biophys J. 2008 Oct;95(7):3192-207. Epub 2008 Jun 27.PMID: 18586844 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune responses to Pneumocystis murina are robust in healthy mice but largely absent in CD40 ligand-deficient mice.

Hernandez-Novoa B, Bishop L, Logun C, Munson PJ, Elnekave E, Rangel ZG, Barb J, Danner RL, Kovacs JA.

J Leukoc Biol. 2008 Aug;84(2):420-30. Epub 2008 May 8.PMID: 18467653 [PubMed - indexed for MEDLINE]Related articlesFree article

Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors.

Zonios DI, Falloon J, Bennett JE, Shaw PA, Chaitt D, Baseler MW, Adelsberger JW, Metcalf JA, Polis MA, Kovacs SJ, Kovacs JA, Davey RT, Lane HC, Masur H, Sereti I.

Blood. 2008 Jul 15;112(2):287-94. Epub 2008 May 2.PMID: 18456875 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy.

Chun TW, Nickle DC, Justement JS, Meyers JH, Roby G, Hallahan CW, Kottilil S, Moir S, Mican JM, Mullins JI, Ward DJ, Kovacs JA, Mannon PJ, Fauci AS.

J Infect Dis. 2008 Mar 1;197(5):714-20.PMID: 18260759 [PubMed - indexed for MEDLINE]Related articles

HIV-infected immunologic non-responders: can we provide a helping hand?

Morse CG, Kovacs JA.

Enferm Infecc Microbiol Clin. 2008 Jan;26(1):1-3. No abstract available. PMID: 18208758 [PubMed - indexed for MEDLINE]Related articlesFree article

Pneumocystis encodes a functional S-adenosylmethionine synthetase gene.

Kutty G, Hernandez-Novoa B, Czapiga M, Kovacs JA.

Eukaryot Cell. 2008 Feb;7(2):258-67. Epub 2007 Dec 7.PMID: 18065654 [PubMed - indexed for MEDLINE]Related articlesFree article

Periodic trends within a series of five-coordinate thiolate-ligated [MII(SMe2N4(tren))]+ (M = Mn, Fe, Co, Ni, Cu, Zn) complexes, including a rare example of a stable CuII-thiolate.

Brines LM, Shearer J, Fender JK, Schweitzer D, Shoner SC, Barnhart D, Kaminsky W, Lovell S, Kovacs JA.

Inorg Chem. 2007 Oct 29;46(22):9267-77. Epub 2007 Sep 15.PMID: 17867686 [PubMed - indexed for MEDLINE]Related articlesFree article

Does atovaquone provide effective prophylaxis for Pneumocystis pneumonia in children with leukemia?

Morse CG, Kovacs JA.

Nat Clin Pract Oncol. 2007 Oct;4(10):566-7. Epub 2007 Aug 14. No abstract available. PMID: 17700556 [PubMed]Related articles

CD4+ T cell responses to interleukin-2 administration in HIV-infected patients are directly related to the baseline level of immune activation.

Sereti I, Sklar P, Ramchandani MS, Read SW, Aggarwal V, Imamichi H, Natarajan V, Metcalf JA, Kovacs JA, Tavel J, Davey RT, Dersimonian R, Lane HC.

J Infect Dis. 2007 Sep 1;196(5):677-83. Epub 2007 Jul 16.PMID: 17674308 [PubMed - indexed for MEDLINE]Related articles

Understanding how the thiolate sulfur contributes to the function of the non-heme iron enzyme superoxide reductase.

Kovacs JA, Brines LM.

Acc Chem Res. 2007 Jul;40(7):501-9. Epub 2007 May 31. Review.PMID: 17536780 [PubMed - indexed for MEDLINE]Related articles

Molecular modeling and mutagenesis of gap junction channels.

Kovacs JA, Baker KA, Altenberg GA, Abagyan R, Yeager M.

Prog Biophys Mol Biol. 2007 May-Jun;94(1-2):15-28. Epub 2007 Mar 23. Review.PMID: 17524457 [PubMed - indexed for MEDLINE]Related articles

Computational prediction of atomic structures of helical membrane proteins aided by EM maps.

Kovacs JA, Yeager M, Abagyan R.

Biophys J. 2007 Sep 15;93(6):1950-9. Epub 2007 May 11.PMID: 17496035 [PubMed - indexed for MEDLINE]Related articlesFree article

ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia.

Maldarelli F, Palmer S, King MS, Wiegand A, Polis MA, Mican J, Kovacs JA, Davey RT, Rock-Kress D, Dewar R, Liu S, Metcalf JA, Rehm C, Brun SC, Hanna GJ, Kempf DJ, Coffin JM, Mellors JW.

PLoS Pathog. 2007 Apr;3(4):e46.PMID: 17411338 [PubMed - indexed for MEDLINE]Related articlesFree article

The incidence and natural history of osteonecrosis in HIV-infected adults.

Morse CG, Mican JM, Jones EC, Joe GO, Rick ME, Formentini E, Kovacs JA.

Clin Infect Dis. 2007 Mar 1;44(5):739-48. Epub 2007 Jan 23.PMID: 17278070 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of rad51 of Pneumocystis.

Kutty G, Kovacs JA.

Gene. 2007 Mar 15;389(2):204-11. Epub 2006 Nov 24.PMID: 17207588 [PubMed - indexed for MEDLINE]Related articles

Rapid antibody quantification and generation of whole proteome antibody response profiles using LIPS (luciferase immunoprecipitation systems).

Burbelo PD, Ching KH, Mattson TL, Light JS, Bishop LR, Kovacs JA.

Biochem Biophys Res Commun. 2007 Jan 26;352(4):889-95. Epub 2006 Dec 6.PMID: 17157815 [PubMed - indexed for MEDLINE]Related articles

Pneumocystis carinii: a fungus resistant to antifungal therapies - mechanisms of action of antipneumocystis drugs.

Russian DA, Kovacs JA.

Drug Resist Updat. 1998 Mar;1(1):16-20.PMID: 17092792 [PubMed]Related articles

A functional model for the cysteinate-ligated non-heme iron enzyme superoxide reductase (SOR).

Kitagawa T, Dey A, Lugo-Mas P, Benedict JB, Kaminsky W, Solomon E, Kovacs JA.

J Am Chem Soc. 2006 Nov 15;128(45):14448-9.PMID: 17090014 [PubMed - indexed for MEDLINE]Related articlesFree article

How does single oxygen atom addition affect the properties of an Fe-nitrile hydratase analogue? The compensatory role of the unmodified thiolate.

Lugo-Mas P, Dey A, Xu L, Davin SD, Benedict J, Kaminsky W, Hodgson KO, Hedman B, Solomon EI, Kovacs JA.

J Am Chem Soc. 2006 Aug 30;128(34):11211-21.PMID: 16925440 [PubMed - indexed for MEDLINE]Related articles

Metabolic and skeletal complications of HIV infection: the price of success.

Morse CG, Kovacs JA.

JAMA. 2006 Aug 16;296(7):844-54.PMID: 16905789 [PubMed - indexed for MEDLINE]Related articles

Lopinavir-ritonavir: effects on endothelial cell function in healthy subjects.

Grubb JR, Dejam A, Voell J, Blackwelder WC, Sklar PA, Kovacs JA, Cannon RO, Masur H, Gladwin MT.

J Infect Dis. 2006 Jun 1;193(11):1516-9. Epub 2006 Apr 27.PMID: 16652279 [PubMed - indexed for MEDLINE]Related articles

Naïve T-cell dynamics in human immunodeficiency virus type 1 infection: effects of highly active antiretroviral therapy provide insights into the mechanisms of naive T-cell depletion.

Di Mascio M, Sereti I, Matthews LT, Natarajan V, Adelsberger J, Lempicki R, Yoder C, Jones E, Chow C, Metcalf JA, Sidorov IA, Dimitrov DS, Polis MA, Kovacs JA.

J Virol. 2006 Mar;80(6):2665-74.PMID: 16501076 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulfur K-edge XAS and DFT calculations on nitrile hydratase: geometric and electronic structure of the non-heme iron active site.

Dey A, Chow M, Taniguchi K, Lugo-Mas P, Davin S, Maeda M, Kovacs JA, Odaka M, Hodgson KO, Hedman B, Solomon EI.

J Am Chem Soc. 2006 Jan 18;128(2):533-41.PMID: 16402841 [PubMed - indexed for MEDLINE]Related articles

Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients.

Kovacs JA, Lempicki RA, Sidorov IA, Adelsberger JW, Sereti I, Sachau W, Kelly G, Metcalf JA, Davey RT Jr, Falloon J, Polis MA, Tavel J, Stevens R, Lambert L, Hosack DA, Bosche M, Issaq HJ, Fox SD, Leitman S, Baseler MW, Masur H, Di Mascio M, Dimitrov DS, Lane HC.

J Clin Invest. 2005 Aug;115(8):2139-48. Epub 2005 Jul 14.PMID: 16025158 [PubMed - indexed for MEDLINE]Related articlesFree article

Representing receptor flexibility in ligand docking through relevant normal modes.

Cavasotto CN, Kovacs JA, Abagyan RA.

J Am Chem Soc. 2005 Jul 6;127(26):9632-40.PMID: 15984891 [PubMed - indexed for MEDLINE]Related articles

In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients.

Sereti I, Imamichi H, Natarajan V, Imamichi T, Ramchandani MS, Badralmaa Y, Berg SC, Metcalf JA, Hahn BK, Shen JM, Powers A, Davey RT, Kovacs JA, Shevach EM, Lane HC.

J Clin Invest. 2005 Jul;115(7):1839-47. Epub 2005 Jun 2.PMID: 15937547 [PubMed - indexed for MEDLINE]Related articlesFree article

Spectroscopy of non-heme iron thiolate complexes: insight into the electronic structure of the low-spin active site of nitrile hydratase.

Kennepohl P, Neese F, Schweitzer D, Jackson HL, Kovacs JA, Solomon EI.

Inorg Chem. 2005 Mar 21;44(6):1826-36.PMID: 15762709 [PubMed - indexed for MEDLINE]Related articles

Role of protons in superoxide reduction by a superoxide reductase analogue.

Theisen RM, Kovacs JA.

Inorg Chem. 2005 Mar 7;44(5):1169-71.PMID: 15732947 [PubMed - indexed for MEDLINE]Related articles

Ligand oxidations in high-spin nickel thiolate complexes and zinc analogues.

Chohan BS, Shoner SC, Kovacs JA, Maroney MJ.

Inorg Chem. 2004 Nov 29;43(24):7726-34.PMID: 15554637 [PubMed - indexed for MEDLINE]Related articles

Steric and electronic control over the reactivity of a thiolate-ligated Fe(II) complex with dioxygen and superoxide: reversible mu-oxo dimer formation.

Theisen RM, Shearer J, Kaminsky W, Kovacs JA.

Inorg Chem. 2004 Nov 29;43(24):7682-90.PMID: 15554633 [PubMed - indexed for MEDLINE]Related articles

Strain typing methods and molecular epidemiology of Pneumocystis pneumonia.

Beard CB, Roux P, Nevez G, Hauser PM, Kovacs JA, Unnasch TR, Lundgren B.

Emerg Infect Dis. 2004 Oct;10(10):1729-35. Review.PMID: 15504257 [PubMed - indexed for MEDLINE]Related articlesFree article

Predictions of protein flexibility: first-order measures.

Kovacs JA, Chacón P, Abagyan R.

Proteins. 2004 Sep 1;56(4):661-8.PMID: 15281119 [PubMed - indexed for MEDLINE]Related articles

HIV Infection, hepatitis C infection, and HAART: hard clinical choices.

Kottilil S, Polis MA, Kovacs JA.

JAMA. 2004 Jul 14;292(2):243-50.PMID: 15249574 [PubMed - indexed for MEDLINE]Related articles

Inability of Pneumocystis organisms to incorporate bromodeoxyuridine suggests the absence of a salvage pathway for thymidine.

Vestereng VH, Kovacs JA.

Microbiology. 2004 May;150(Pt 5):1179-82.PMID: 15133078 [PubMed - indexed for MEDLINE]Related articlesFree article

A prospective, blinded study of quantitative touch-down polymerase chain reaction using oral-wash samples for diagnosis of Pneumocystis pneumonia in HIV-infected patients.

Larsen HH, Huang L, Kovacs JA, Crothers K, Silcott VA, Morris A, Turner JR, Beard CB, Masur H, Fischer SH.

J Infect Dis. 2004 May 1;189(9):1679-83. Epub 2004 Apr 16.PMID: 15116305 [PubMed - indexed for MEDLINE]Related articles

IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation.

Sereti I, Anthony KB, Martinez-Wilson H, Lempicki R, Adelsberger J, Metcalf JA, Hallahan CW, Follmann D, Davey RT, Kovacs JA, Lane HC.

Blood. 2004 Aug 1;104(3):775-80. Epub 2004 Apr 13.PMID: 15090457 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative real-time polymerase chain-reaction assay allows characterization of pneumocystis infection in immunocompetent mice.

Vestereng VH, Bishop LR, Hernandez B, Kutty G, Larsen HH, Kovacs JA.

J Infect Dis. 2004 Apr 15;189(8):1540-4. Epub 2004 Apr 2.PMID: 15073693 [PubMed - indexed for MEDLINE]Related articles