PubMed

ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors.

Schmalhofer WA, Calhoun J, Burrows R, Bailey T, Kohler MG, Weinglass AB, Kaczorowski GJ, Garcia ML, Koltzenburg M, Priest BT.

Mol Pharmacol. 2008 Nov;74(5):1476-84. Epub 2008 Aug 26.PMID: 18728100 [PubMed - indexed for MEDLINE]Related articlesFree article

Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.

Weinglass AB, Köhler MG, Nketiah EO, Liu J, Schmalhofer W, Thomas A, Williams B, Beers L, Smith L, Hafey M, Bleasby K, Leone J, Tang YS, Braun M, Ujjainwalla F, McCann ME, Kaczorowski GJ, Garcia ML.

Mol Pharmacol. 2008 Apr;73(4):1072-84. Epub 2008 Jan 10.PMID: 18187582 [PubMed - indexed for MEDLINE]Related articlesFree article

Blockers of the delayed-rectifier potassium current in pancreatic beta-cells enhance glucose-dependent insulin secretion.

Herrington J, Zhou YP, Bugianesi RM, Dulski PM, Feng Y, Warren VA, Smith MM, Kohler MG, Garsky VM, Sanchez M, Wagner M, Raphaelli K, Banerjee P, Ahaghotu C, Wunderler D, Priest BT, Mehl JT, Garcia ML, McManus OB, Kaczorowski GJ, Slaughter RS.

Diabetes. 2006 Apr;55(4):1034-42. Erratum in: Diabetes. 2006 Jun;55(6):1904. PMID: 16567526 [PubMed - indexed for MEDLINE]Related articlesFree article

A high-capacity membrane potential FRET-based assay for NaV1.8 channels.

Liu CJ, Priest BT, Bugianesi RM, Dulski PM, Felix JP, Dick IE, Brochu RM, Knaus HG, Middleton RE, Kaczorowski GJ, Slaughter RS, Garcia ML, Köhler MG.

Assay Drug Dev Technol. 2006 Feb;4(1):37-48.PMID: 16506887 [PubMed - indexed for MEDLINE]Related articles

Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats.

Lindia JA, Köhler MG, Martin WJ, Abbadie C.

Pain. 2005 Sep;117(1-2):145-53.PMID: 16061326 [PubMed - indexed for MEDLINE]Related articles

Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior.

Priest BT, Murphy BA, Lindia JA, Diaz C, Abbadie C, Ritter AM, Liberator P, Iyer LM, Kash SF, Kohler MG, Kaczorowski GJ, MacIntyre DE, Martin WJ.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9382-7. Epub 2005 Jun 17.PMID: 15964986 [PubMed - indexed for MEDLINE]Related articlesFree article

Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic beta-cells.

Herrington J, Sanchez M, Wunderler D, Yan L, Bugianesi RM, Dick IE, Clark SA, Brochu RM, Priest BT, Kohler MG, McManus OB.

J Physiol. 2005 Aug 15;567(Pt 1):159-75. Epub 2005 Jun 2.PMID: 15932888 [PubMed - indexed for MEDLINE]Related articlesFree article

The behavioral and neuroanatomical effects of IB4-saporin treatment in rat models of nociceptive and neuropathic pain.

Tarpley JW, Kohler MG, Martin WJ.

Brain Res. 2004 Dec 10;1029(1):65-76.PMID: 15533317 [PubMed - indexed for MEDLINE]Related articles

A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model.

Priest BT, Garcia ML, Middleton RE, Brochu RM, Clark S, Dai G, Dick IE, Felix JP, Liu CJ, Reiseter BS, Schmalhofer WA, Shao PP, Tang YS, Chou MZ, Kohler MG, Smith MM, Warren VA, Williams BS, Cohen CJ, Martin WJ, Meinke PT, Parsons WH, Wafford KA, Kaczorowski GJ.

Biochemistry. 2004 Aug 3;43(30):9866-76.PMID: 15274641 [PubMed - indexed for MEDLINE]Related articles

Expression of voltage-gated potassium channels in human and rhesus pancreatic islets.

Yan L, Figueroa DJ, Austin CP, Liu Y, Bugianesi RM, Slaughter RS, Kaczorowski GJ, Kohler MG.

Diabetes. 2004 Mar;53(3):597-607.PMID: 14988243 [PubMed - indexed for MEDLINE]Related articlesFree article

Two tarantula peptides inhibit activation of multiple sodium channels.

Middleton RE, Warren VA, Kraus RL, Hwang JC, Liu CJ, Dai G, Brochu RM, Kohler MG, Gao YD, Garsky VM, Bogusky MJ, Mehl JT, Cohen CJ, Smith MM.

Biochemistry. 2002 Dec 17;41(50):14734-47.PMID: 12475222 [PubMed - indexed for MEDLINE]Related articles