PubMed

Effect of Genetic Variation in the Human Fatty Acid Synthase Gene (FASN) on Obesity and Fat Depot-Specific mRNA Expression.

Schleinitz D, Klöting N, Körner A, Berndt J, Reichenbächer M, Tönjes A, Ruschke K, Böttcher Y, Dietrich K, Enigk B, Filz M, Schön MR, Jenkner J, Kiess W, Stumvoll M, Blüher M, Kovacs P.

Obesity (Silver Spring). 2009 Oct 29. [Epub ahead of print]PMID: 19876008 [PubMed - as supplied by publisher]Related articles

Genes on rat chromosomes 3, 5, 10, and 16 are linked with facets of metabolic syndrome.

Baguhl R, Wilke B, Klöting N, Klöting I.

Obesity (Silver Spring). 2009 Jun;17(6):1215-9. Epub 2009 Feb 19.PMID: 19584880 [PubMed - indexed for MEDLINE]Related articles

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity.

Böttcher Y, Unbehauen H, Klöting N, Ruschke K, Körner A, Schleinitz D, Tönjes A, Enigk B, Wolf S, Dietrich K, Koriath M, Scholz GH, Tseng YH, Dietrich A, Schön MR, Kiess W, Stumvoll M, Blüher M, Kovacs P.

Diabetes. 2009 Sep;58(9):2119-28. Epub 2009 Jun 5.PMID: 19502417 [PubMed - indexed for MEDLINE]Related articles

Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice.

Ruschke K, Ebelt H, Klöting N, Boettger T, Raum K, Blüher M, Braun T.

PLoS One. 2009;4(5):e5516. Epub 2009 May 13.PMID: 19436734 [PubMed - indexed for MEDLINE]Related articlesFree article

Antioxidants prevent health-promoting effects of physical exercise in humans.

Ristow M, Zarse K, Oberbach A, Klöting N, Birringer M, Kiehntopf M, Stumvoll M, Kahn CR, Blüher M.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8665-70. Epub 2009 May 11.PMID: 19433800 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity.

Blüher M, Bashan N, Shai I, Harman-Boehm I, Tarnovscki T, Avinaoch E, Stumvoll M, Dietrich A, Klöting N, Rudich A.

J Clin Endocrinol Metab. 2009 Jul;94(7):2507-15. Epub 2009 Apr 7.PMID: 19351724 [PubMed - indexed for MEDLINE]Related articles

MicroRNA expression in human omental and subcutaneous adipose tissue.

Klöting N, Berthold S, Kovacs P, Schön MR, Fasshauer M, Ruschke K, Stumvoll M, Blüher M.

PLoS One. 2009;4(3):e4699. Epub 2009 Mar 4.PMID: 19259271 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue.

Youn BS, Bang SI, Klöting N, Park JW, Lee N, Oh JE, Pi KB, Lee TH, Ruschke K, Fasshauer M, Stumvoll M, Blüher M.

Diabetes. 2009 Mar;58(3):627-36. Epub 2008 Dec 3.PMID: 19056610 [PubMed - indexed for MEDLINE]Related articlesFree article

Vaspin serum concentrations in patients with carotid stenosis.

Aust G, Richter O, Rohm S, Kerner C, Hauss J, Klöting N, Ruschke K, Kovacs P, Youn BS, Blüher M.

Atherosclerosis. 2009 May;204(1):262-6. Epub 2008 Sep 2.PMID: 18848328 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus.

Kovacs P, Berndt J, Ruschke K, Klöting N, Schön MR, Körner A, Stumvoll M, Blüher M.

Metabolism. 2008 Sep;57(9):1227-31.PMID: 18702948 [PubMed - indexed for MEDLINE]Related articles

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth.

Klöting N, Koch L, Wunderlich T, Kern M, Ruschke K, Krone W, Brüning JC, Blüher M.

Diabetes. 2008 Aug;57(8):2074-82. Epub 2008 Apr 28.PMID: 18443199 [PubMed - indexed for MEDLINE]Related articlesFree article

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans.

Klöting N, Schleinitz D, Ruschke K, Berndt J, Fasshauer M, Tönjes A, Schön MR, Kovacs P, Stumvoll M, Blüher M.

Diabetologia. 2008 Apr;51(4):641-7. Epub 2008 Feb 5.PMID: 18251005 [PubMed - indexed for MEDLINE]Related articles

Adipose triglyceride lipase gene expression in human visceral obesity.

Berndt J, Kralisch S, Klöting N, Ruschke K, Kern M, Fasshauer M, Schön MR, Stumvoll M, Blüher M.

Exp Clin Endocrinol Diabetes. 2008 Apr;116(4):203-10. Epub 2007 Dec 10.PMID: 18072017 [PubMed - indexed for MEDLINE]Related articles

Serum vaspin concentrations in human obesity and type 2 diabetes.

Youn BS, Klöting N, Kratzsch J, Lee N, Park JW, Song ES, Ruschke K, Oberbach A, Fasshauer M, Stumvoll M, Blüher M.

Diabetes. 2008 Feb;57(2):372-7. Epub 2007 Nov 8.PMID: 17991760 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training.

Blüher M, Williams CJ, Klöting N, Hsi A, Ruschke K, Oberbach A, Fasshauer M, Berndt J, Schön MR, Wolk A, Stumvoll M, Mantzoros CS.

Diabetes Care. 2007 Dec;30(12):3110-5. Epub 2007 Sep 18.PMID: 17878241 [PubMed - indexed for MEDLINE]Related articlesFree article

Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats.

Kuttler B, Wanka H, Klöting N, Gerstmayer B, Volk HD, Sawitzki B, Ritter T.

J Cell Mol Med. 2007 Jul-Aug;11(4):868-80.PMID: 17760846 [PubMed - indexed for MEDLINE]Related articles

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.

Kovacs P, Geyer M, Berndt J, Klöting N, Graham TE, Böttcher Y, Enigk B, Tönjes A, Schleinitz D, Schön MR, Kahn BB, Blüher M, Stumvoll M.

Diabetes. 2007 Dec;56(12):3095-100. Epub 2007 Aug 29.PMID: 17728376 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.

Klöting N, Graham TE, Berndt J, Kralisch S, Kovacs P, Wason CJ, Fasshauer M, Schön MR, Stumvoll M, Blüher M, Kahn BB.

Cell Metab. 2007 Jul;6(1):79-87.PMID: 17618858 [PubMed - indexed for MEDLINE]Related articles

Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes.

Berndt J, Kovacs P, Ruschke K, Klöting N, Fasshauer M, Schön MR, Körner A, Stumvoll M, Blüher M.

Diabetologia. 2007 Jul;50(7):1472-80. Epub 2007 May 11.PMID: 17492427 [PubMed - indexed for MEDLINE]Related articles

Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity.

Harman-Boehm I, Blüher M, Redel H, Sion-Vardy N, Ovadia S, Avinoach E, Shai I, Klöting N, Stumvoll M, Bashan N, Rudich A.

J Clin Endocrinol Metab. 2007 Jun;92(6):2240-7. Epub 2007 Mar 20.PMID: 17374712 [PubMed - indexed for MEDLINE]Related articlesFree article

[The biology of visceral fat]

Klöting N, Stumvoll M, Blüher M.

Internist (Berl). 2007 Feb;48(2):126-33. Review. German. PMID: 17216235 [PubMed - indexed for MEDLINE]Related articles

Triplet repeat in the Repin1 3'-untranslated region on rat chromosome 4 correlates with facets of the metabolic syndrome.

Klöting N, Wilke B, Klöting I.

Diabetes Metab Res Rev. 2007 Jul;23(5):406-10.PMID: 17173329 [PubMed - indexed for MEDLINE]Related articles

Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity.

Blüher M, Engeli S, Klöting N, Berndt J, Fasshauer M, Bátkai S, Pacher P, Schön MR, Jordan J, Stumvoll M.

Diabetes. 2006 Nov;55(11):3053-60.PMID: 17065342 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulates expression of the nerve growth factor (NGF) receptors TrkA and p75NTR in rat islets and INS-1E beta-cells.

Raile K, Klammt J, Garten A, Laue S, Blüher M, Kralisch S, Klöting N, Kiess W.

Regul Pept. 2006 Jul 15;135(1-2):30-8. Epub 2006 Apr 27.PMID: 16644033 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.

Böttcher Y, Teupser D, Enigk B, Berndt J, Klöting N, Schön MR, Thiery J, Blüher M, Stumvoll M, Kovacs P.

J Clin Endocrinol Metab. 2006 Jul;91(7):2725-31. Epub 2006 Apr 24.PMID: 16636125 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance.

Oberbach A, Tönjes A, Klöting N, Fasshauer M, Kratzsch J, Busse MW, Paschke R, Stumvoll M, Blüher M.

Eur J Endocrinol. 2006 Apr;154(4):577-85.PMID: 16556721 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training.

Blüher M, Bullen JW Jr, Lee JH, Kralisch S, Fasshauer M, Klöting N, Niebauer J, Schön MR, Williams CJ, Mantzoros CS.

J Clin Endocrinol Metab. 2006 Jun;91(6):2310-6. Epub 2006 Mar 21.PMID: 16551730 [PubMed - indexed for MEDLINE]Related articlesFree article

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes.

Klöting N, Berndt J, Kralisch S, Kovacs P, Fasshauer M, Schön MR, Stumvoll M, Blüher M.

Biochem Biophys Res Commun. 2006 Jan 6;339(1):430-6. Epub 2005 Nov 15.PMID: 16298335 [PubMed - indexed for MEDLINE]Related articles

Is there an autoimmune process in bone? Gene expression studies in diabetic and nondiabetic BB rats as well as BB rat-related and -unrelated rat strains.

Klöting N, Follak N, Klöting I.

Physiol Genomics. 2005 Dec 14;24(1):59-64. Epub 2005 Sep 27.PMID: 16189279 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma visfatin concentrations and fat depot-specific mRNA expression in humans.

Berndt J, Klöting N, Kralisch S, Kovacs P, Fasshauer M, Schön MR, Stumvoll M, Blüher M.

Diabetes. 2005 Oct;54(10):2911-6.PMID: 16186392 [PubMed - indexed for MEDLINE]Related articlesFree article

Extended longevity and insulin signaling in adipose tissue.

Klöting N, Blüher M.

Exp Gerontol. 2005 Nov;40(11):878-83. Epub 2005 Aug 25. Review.PMID: 16125891 [PubMed - indexed for MEDLINE]Related articles

Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells.

Raile K, Klammt J, Laue S, Garten A, Blüher M, Kralisch S, Klöting N, Kiess W.

Diabetologia. 2005 Sep;48(9):1798-809. Epub 2005 Jul 29.PMID: 16052330 [PubMed - indexed for MEDLINE]Related articles

The polygenetically inherited metabolic syndrome of WOKW rats is associated with insulin resistance and altered gene expression in adipose tissue.

Klöting N, Blüher M, Klöting I.

Diabetes Metab Res Rev. 2006 Mar-Apr;22(2):146-54.PMID: 16041833 [PubMed - indexed for MEDLINE]Related articles

Visfatin: gene expression in isolated adipocytes and sequence analysis in obese WOKW rats compared with lean control rats.

Klöting N, Klöting I.

Biochem Biophys Res Commun. 2005 Jul 15;332(4):1070-2.PMID: 15922301 [PubMed - indexed for MEDLINE]Related articles

Alleles on rat chromosome 4 (D4Got41-Fabp1/Tacr1) regulate subphenotypes of obesity.

Klöting N, Wilke B, Klöting I.

Obes Res. 2005 Mar;13(3):589-95.PMID: 15833945 [PubMed - indexed for MEDLINE]Related articles

Diabetes per se and metabolic state influence gene expression in tissue-dependent manner of BB/OK rats.

Klöting N, Follak N, Klöting I.

Diabetes Metab Res Rev. 2005 May-Jun;21(3):281-7.PMID: 15619288 [PubMed - indexed for MEDLINE]Related articles

Congenic mapping of type 1 diabetes--protective gene(s) in an interval of 4 Mb on rat chromosome 6q32.

Klöting N, Klöting I.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):388-94.PMID: 15369764 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.

Klöting N, Klöting I.

Mol Genet Metab. 2004 Jul;82(3):255-9.PMID: 15234341 [PubMed - indexed for MEDLINE]Related articles

Phenotypic and genetic analyses of subcongenic BB.SHR rat lines shorten the region on chromosome 4 bearing gene(s) for underlying facets of metabolic syndrome.

Klöting N, Wilke B, Klöting I.

Physiol Genomics. 2004 Aug 11;18(3):325-30.PMID: 15173549 [PubMed - indexed for MEDLINE]Related articles

Aminoguanidine downregulates expression of cytokine-induced Fas and inducible nitric oxide synthase but not cytokine-enhanced surface antigens of rat islet cells.

Kuttler B, Steveling A, Klöting N, Morgenstern O, Wanka H.

Biochem Pharmacol. 2003 Dec 15;66(12):2437-48.PMID: 14637201 [PubMed - indexed for MEDLINE]Related articles

CD14 triggers autoimmune Type 1 diabetes in the NOD mouse.

Klöting N, Klöting I, Jack RS.

Diabetologia. 2004 Jan;47(1):151-2. Epub 2003 Nov 12. No abstract available. PMID: 14614560 [PubMed - indexed for MEDLINE]Related articles

Is there relatedness between maternal lines of Type 1 diabetic patients?

Klöting I, Poetsch M, Müller-Myhsok B, Rjasanowski I, Kerner W, Klöting N.

Diabetologia. 2003 Mar;46(3):441-2. Epub 2003 Mar 1. No abstract available. PMID: 12687346 [PubMed - indexed for MEDLINE]Related articles

Alleles of diabetes-resistant BN rats contribute to insulin-dependent type 1 diabetes mellitus.

Klöting I, van den Brandt J, Klöting N, Radović B.

J Autoimmun. 2003 Mar;20(2):119-23.PMID: 12657525 [PubMed - indexed for MEDLINE]Related articles