PubMed

Urinary Albumin Excretion, HMW Adiponectin, and Insulin Sensitivity in Type 2 Diabetic Patients Undergoing Bariatric Surgery.

Navaneethan SD, Kelly KR, Sabbagh F, Schauer PR, Kirwan JP, Kashyap SR.

Obes Surg. 2009 Nov 20. [Epub ahead of print]PMID: 19936853 [PubMed - as supplied by publisher]Related articles

Free Fatty Acid-Induced Hepatic Insulin Resistance is Attenuated Following Lifestyle Intervention in Obese Individuals with Impaired Glucose Tolerance.

Haus JM, Solomon TP, Marchetti CM, Edmison JM, González F, Kirwan JP.

J Clin Endocrinol Metab. 2009 Nov 11. [Epub ahead of print]PMID: 19906790 [PubMed - as supplied by publisher]Related articles

Hormonal and metabolic factors associated with variations in insulin sensitivity in human pregnancy.

McIntyre HD, Chang AM, Callaway LK, Cowley DM, Dyer AR, Radaelli T, Farrell KA, Huston-Presley LP, Amini SB, Kirwan JP, Catalano PM; for the HAPO Study Cooperative Research Group.

Diabetes Care. 2009 Oct 30. [Epub ahead of print]PMID: 19880583 [PubMed - as supplied by publisher]Related articles

Exercise Training and Dietary Glycemic Load May Have Synergistic Effects on Insulin Resistance in Older Obese Adults.

Kirwan JP, Barkoukis H, Brooks LM, Marchetti CM, Stetzer BP, Gonzalez F.

Ann Nutr Metab. 2009 Oct 16;55(4):326-333. [Epub ahead of print]PMID: 19844089 [PubMed - as supplied by publisher]Related articles

Retinol-binding Protein 4 (RBP4) Protein Expression Is Increased in Omental Adipose Tissue of Severely Obese Patients.

Kelly KR, Kashyap SR, O'Leary VB, Major J, Schauer PR, Kirwan JP.

Obesity (Silver Spring). 2009 Oct 8. [Epub ahead of print]PMID: 19816414 [PubMed - as supplied by publisher]Related articles

Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans.

Solomon TP, Haus JM, Kelly KR, Cook MD, Riccardi M, Rocco M, Kashyap SR, Barkoukis H, Kirwan JP.

Am J Clin Nutr. 2009 Nov;90(5):1222-9. Epub 2009 Sep 30.PMID: 19793849 [PubMed - in process]Related articles

Acute altitude-induced hypoxia suppresses plasma glucose and leptin in healthy humans.

Kelly KR, Williamson DL, Fealy CE, Kriz DA, Krishnan RK, Huang H, Ahn J, Loomis JL, Kirwan JP.

Metabolism. 2009 Sep 16. [Epub ahead of print]PMID: 19765784 [PubMed - as supplied by publisher]Related articles

Identification of a unique "stability control region" that controls protein stability of tropomyosin: A two-stranded alpha-helical coiled-coil.

Hodges RS, Mills J, McReynolds S, Kirwan JP, Tripet B, Osguthorpe D.

J Mol Biol. 2009 Sep 25;392(3):747-62. Epub 2009 Jul 21.PMID: 19627992 [PubMed - in process]Related articles

Effects of exercise training and diet on lipid kinetics during free fatty acid-induced insulin resistance in older obese humans with impaired glucose tolerance.

Solomon TP, Haus JM, Marchetti CM, Stanley WC, Kirwan JP.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E552-9. Epub 2009 Jun 16.PMID: 19531640 [PubMed - indexed for MEDLINE]Related articles

Decreased visfatin after exercise training correlates with improved glucose tolerance.

Haus JM, Solomon TP, Marchetti CM, O'Leary VB, Brooks LM, Gonzalez F, Kirwan JP.

Med Sci Sports Exerc. 2009 Jun;41(6):1255-60.PMID: 19461540 [PubMed - in process]Related articles

Unique role of clusters of electrostatic attractions in controlling the stability of two-stranded alpha-helical coiled-coils.

Kirwan JP, Kwok SC, McReynolds S, Mills J, Osguthorpe D, Hodges RS.

Adv Exp Med Biol. 2009;611:77-8. No abstract available. PMID: 19400101 [PubMed - indexed for MEDLINE]Related articles

Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus.

Kirwan JP, Solomon TP, Wojta DM, Staten MA, Holloszy JO.

Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E151-6. Epub 2009 Apr 21.PMID: 19383872 [PubMed - indexed for MEDLINE]Related articles

Evidence of proatherogenic inflammation in polycystic ovary syndrome.

González F, Rote NS, Minium J, Kirwan JP.

Metabolism. 2009 Jul;58(7):954-62.PMID: 19375763 [PubMed - indexed for MEDLINE]Related articles

The glucose-dependent insulinotropic polypeptide and glucose-stimulated insulin response to exercise training and diet in obesity.

Kelly KR, Brooks LM, Solomon TP, Kashyap SR, O'Leary VB, Kirwan JP.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1269-74. Epub 2009 Apr 7.PMID: 19351807 [PubMed - indexed for MEDLINE]Related articles

Effects of exercise and caloric restriction on insulin resistance and cardiometabolic risk factors in older obese adults--a randomized clinical trial.

Yassine HN, Marchetti CM, Krishnan RK, Vrobel TR, Gonzalez F, Kirwan JP.

J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):90-5. Epub 2009 Jan 20.PMID: 19164269 [PubMed - indexed for MEDLINE]Related articles

Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance.

Haus JM, Kashyap SR, Kasumov T, Zhang R, Kelly KR, Defronzo RA, Kirwan JP.

Diabetes. 2009 Feb;58(2):337-43. Epub 2008 Nov 13.PMID: 19008343 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of aging on basal fat oxidation in obese humans.

Solomon TP, Marchetti CM, Krishnan RK, Gonzalez F, Kirwan JP.

Metabolism. 2008 Aug;57(8):1141-7.PMID: 18640394 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise and diet enhance fat oxidation and reduce insulin resistance in older obese adults.

Solomon TP, Sistrun SN, Krishnan RK, Del Aguila LF, Marchetti CM, O'Carroll SM, O'Leary VB, Kirwan JP.

J Appl Physiol. 2008 May;104(5):1313-9. Epub 2008 Mar 6.PMID: 18323464 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased skeletal muscle tumor necrosis factor-alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum.

Friedman JE, Kirwan JP, Jing M, Presley L, Catalano PM.

Diabetes. 2008 Mar;57(3):606-13. Epub 2007 Dec 14.PMID: 18083784 [PubMed - indexed for MEDLINE]Related articlesFree article

A high glycemic meal suppresses the postprandial leptin response in normal healthy adults.

Barkoukis H, Marchetti CM, Nolan B, Sistrun SN, Krishnan RK, Kirwan JP.

Ann Nutr Metab. 2007;51(6):512-8. Epub 2007 Dec 10.PMID: 18073462 [PubMed - indexed for MEDLINE]Related articles

Computational model of glucose homeostasis during exercise.

Kim J, Saidel GM, Kirwan JP, Cabrera ME.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:311-4.PMID: 17946814 [PubMed - indexed for MEDLINE]Related articles

Obese reproductive-age women exhibit a proatherogenic inflammatory response during hyperglycemia.

González F, Rote NS, Minium J, O'leary VB, Kirwan JP.

Obesity (Silver Spring). 2007 Oct;15(10):2436-44.PMID: 17925469 [PubMed - indexed for MEDLINE]Related articles

Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse.

Hakimi P, Yang J, Casadesus G, Massillon D, Tolentino-Silva F, Nye CK, Cabrera ME, Hagen DR, Utter CB, Baghdy Y, Johnson DH, Wilson DL, Kirwan JP, Kalhan SC, Hanson RW.

J Biol Chem. 2007 Nov 9;282(45):32844-55. Epub 2007 Aug 23.PMID: 17716967 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes.

Barbour LA, McCurdy CE, Hernandez TL, Kirwan JP, Catalano PM, Friedman JE.

Diabetes Care. 2007 Jul;30 Suppl 2:S112-9. No abstract available. Erratum in: Diabetes Care. 2007 Dec;30(12):3154. PMID: 17596458 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced adiponectin multimer ratio and skeletal muscle adiponectin receptor expression following exercise training and diet in older insulin-resistant adults.

O'Leary VB, Jorett AE, Marchetti CM, Gonzalez F, Phillips SA, Ciaraldi TP, Kirwan JP.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E421-7. Epub 2007 May 8.PMID: 17488807 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of chromium supplementation on glycogen synthesis after high-intensity exercise.

Volek JS, Silvestre R, Kirwan JP, Sharman MJ, Judelson DA, Spiering BA, Vingren JL, Maresh CM, Vanheest JL, Kraemer WJ.

Med Sci Sports Exerc. 2006 Dec;38(12):2102-9.PMID: 17146316 [PubMed - indexed for MEDLINE]Related articles

In vitro evidence that hyperglycemia stimulates tumor necrosis factor-alpha release in obese women with polycystic ovary syndrome.

González F, Rote NS, Minium J, Kirwan JP.

J Endocrinol. 2006 Mar;188(3):521-9.PMID: 16522732 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased activation of nuclear factor kappaB triggers inflammation and insulin resistance in polycystic ovary syndrome.

González F, Rote NS, Minium J, Kirwan JP.

J Clin Endocrinol Metab. 2006 Apr;91(4):1508-12. Epub 2006 Feb 7.PMID: 16464947 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered tumor necrosis factor alpha release from mononuclear cells of obese reproductive-age women during hyperglycemia.

González F, Minium J, Rote NS, Kirwan JP.

Metabolism. 2006 Feb;55(2):271-6.PMID: 16423637 [PubMed - indexed for MEDLINE]Related articles

The gastroenteroinsular response to glucose ingestion during postexercise recovery.

O'Connor AM, Pola S, Ward BM, Fillmore D, Buchanan KD, Kirwan JP.

Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1155-61. Epub 2006 Jan 10.PMID: 16403776 [PubMed - indexed for MEDLINE]Related articlesFree article

Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI.

Kirwan JP, Gould TA, Schweizer HP, Bearden SW, Murphy RC, Churchill ME.

J Bacteriol. 2006 Jan;188(2):784-8.PMID: 16385067 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat.

O'Leary VB, Marchetti CM, Krishnan RK, Stetzer BP, Gonzalez F, Kirwan JP.

J Appl Physiol. 2006 May;100(5):1584-9. Epub 2005 Dec 22.PMID: 16373444 [PubMed - indexed for MEDLINE]Related articlesFree article

Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome.

González F, Rote NS, Minium J, Kirwan JP.

J Clin Endocrinol Metab. 2006 Jan;91(1):336-40. Epub 2005 Oct 25.PMID: 16249279 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia alters tumor necrosis factor-alpha release from mononuclear cells in women with polycystic ovary syndrome.

González F, Minium J, Rote NS, Kirwan JP.

J Clin Endocrinol Metab. 2005 Sep;90(9):5336-42. Epub 2005 Jun 28.PMID: 15985479 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling.

Kirwan JP, Varastehpour A, Jing M, Presley L, Shao J, Friedman JE, Catalano PM.

J Clin Endocrinol Metab. 2004 Sep;89(9):4678-84.PMID: 15356080 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signalling, exercise and cellular integrity.

Kirwan JP, del Aguila LF.

Biochem Soc Trans. 2003 Dec;31(Pt 6):1281-5. Review.PMID: 14641043 [PubMed - indexed for MEDLINE]Related articles

Glucose clearance is delayed after hyperglycemia in healthy elderly men.

Krishnan RK, Evans WJ, Kirwan JP.

J Nutr. 2003 Jul;133(7):2363-6.PMID: 12840207 [PubMed - indexed for MEDLINE]Related articlesFree article

Maternal factors that determine neonatal size and body fat.

Catalano PM, Kirwan JP.

Curr Diab Rep. 2001 Aug;1(1):71-7. Review.PMID: 12762960 [PubMed - indexed for MEDLINE]Related articles

Gestational diabetes and insulin resistance: role in short- and long-term implications for mother and fetus.

Catalano PM, Kirwan JP, Haugel-de Mouzon S, King J.

J Nutr. 2003 May;133(5 Suppl 2):1674S-1683S. Review.PMID: 12730484 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired substrate oxidation in healthy elderly men after eccentric exercise.

Krishnan RK, Evans WJ, Kirwan JP.

J Appl Physiol. 2003 Feb;94(2):716-23. Epub 2002 Oct 25.PMID: 12433853 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical utility and approaches for estimating insulin sensitivity in pregnancy.

Catalano PM, Kirwan JP.

Semin Perinatol. 2002 Jun;26(3):181-9.PMID: 12099307 [PubMed - indexed for MEDLINE]Related articles

TNF-alpha is a predictor of insulin resistance in human pregnancy.

Kirwan JP, Hauguel-De Mouzon S, Lepercq J, Challier JC, Huston-Presley L, Friedman JE, Kalhan SC, Catalano PM.

Diabetes. 2002 Jul;51(7):2207-13.PMID: 12086951 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of insulin signaling in human skeletal muscle in response to exercise.

Kirwan JP, Jing M.

Exerc Sport Sci Rev. 2002 Apr;30(2):85-90. Review.PMID: 11991543 [PubMed - indexed for MEDLINE]Related articles

Physiological and metabolic characteristics of elite tug of war athletes.

Warrington G, Ryan C, Murray F, Duffy P, Kirwan JP.

Br J Sports Med. 2001 Dec;35(6):396-401.PMID: 11726473 [PubMed - indexed for MEDLINE]Related articlesFree article

Euglycemic clamp study in clozapine-induced diabetic ketoacidosis.

Avram AM, Patel V, Taylor HC, Kirwan JP, Kalhan S.

Ann Pharmacother. 2001 Nov;35(11):1381-7.PMID: 11724088 [PubMed - indexed for MEDLINE]Related articles

Human aging is associated with altered TNF-alpha production during hyperglycemia and hyperinsulinemia.

Kirwan JP, Krishnan RK, Weaver JA, Del Aguila LF, Evans WJ.

Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1137-43.PMID: 11701426 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of a moderate glycemic meal on exercise duration and substrate utilization.

Kirwan JP, O'Gorman DJ, Cyr-Campbell D, Campbell WW, Yarasheski KE, Evans WJ.

Med Sci Sports Exerc. 2001 Sep;33(9):1517-23.PMID: 11528341 [PubMed - indexed for MEDLINE]Related articles

Clinically useful estimates of insulin sensitivity during pregnancy: validation studies in women with normal glucose tolerance and gestational diabetes mellitus.

Kirwan JP, Huston-Presley L, Kalhan SC, Catalano PM.

Diabetes Care. 2001 Sep;24(9):1602-7.PMID: 11522706 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of moderate and high glycemic index meals on metabolism and exercise performance.

Kirwan JP, Cyr-Campbell D, Campbell WW, Scheiber J, Evans WJ.

Metabolism. 2001 Jul;50(7):849-55.PMID: 11436193 [PubMed - indexed for MEDLINE]Related articles

Insulin and exercise differentially regulate PI3-kinase and glycogen synthase in human skeletal muscle.

O'Gorman DJ, Del Aguila LF, Williamson DL, Krishnan RK, Kirwan JP.

J Appl Physiol. 2000 Oct;89(4):1412-9.PMID: 11007576 [PubMed - indexed for MEDLINE]Related articlesFree article