PubMed

Long-term effect of modification of dietary protein intake on the progression of diabetic nephropathy: a randomised controlled trial.

Koya D, Haneda M, Inomata S, Suzuki Y, Suzuki D, Makino H, Shikata K, Murakami Y, Tomino Y, Yamada K, Araki SI, Kashiwagi A, Kikkawa R; Low-Protein Diet Study Group.

Diabetologia. 2009 Oct;52(10):2037-45. Epub 2009 Aug 4.PMID: 19652945 [PubMed - in process]Related articlesFree article

Steroid-induced crisis and rhabdomyolysis in a patient with pheochromocytoma: A case report and review.

Takahashi N, Shimada T, Tanabe K, Yoshitomi H, Murakami Y, Ishibashi Y, Kikkawa R, Yano S, Araki A, Inoue A.

Int J Cardiol. 2009 Jan 31. [Epub ahead of print]PMID: 19187985 [PubMed - as supplied by publisher]Related articles

Experience with laparoscopic sleeve gastrectomy for morbid versus super morbid obesity.

Tagaya N, Kasama K, Kikkawa R, Kanahira E, Umezawa A, Oshiro T, Negishi Y, Kurokawa Y, Nakazato T, Kubota K.

Obes Surg. 2009 Oct;19(10):1371-6. Epub 2008 Dec 9.PMID: 19067089 [PubMed - in process]Related articles

International Symposium on Diabetic Nephropathy. Preface.

Kikkawa R.

Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S1. No abstract available. PMID: 18994671 [PubMed - indexed for MEDLINE]Related articles

Clinical impact of reducing microalbuminuria in patients with type 2 diabetes mellitus.

Araki S, Haneda M, Koya D, Kashiwagi A, Uzu T, Kikkawa R.

Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S54-8. Epub 2008 Oct 22. Review.PMID: 18947896 [PubMed - indexed for MEDLINE]Related articles

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, Andersen G, Ng DP, Holmkvist J, Borch-Johnsen K, Jørgensen T, Sandbaek A, Lauritzen T, Hansen T, Nurbaya S, Tsunoda T, Kubo M, Babazono T, Hirose H, Hayashi M, Iwamoto Y, Kashiwagi A, Kaku K, Kawamori R, Tai ES, Pedersen O, Kamatani N, Kadowaki T, Kikkawa R, Nakamura Y, Maeda S.

Nat Genet. 2008 Sep;40(9):1098-102.PMID: 18711366 [PubMed - indexed for MEDLINE]Related articles

Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population.

Maeda S, Osawa N, Hayashi T, Tsukada S, Kobayashi M, Kikkawa R.

Kidney Int Suppl. 2007 Aug;(106):S43-8.PMID: 17653210 [PubMed - indexed for MEDLINE]Related articles

Genomic cluster and network analysis for predictive screening for hepatotoxicity.

Fukushima T, Kikkawa R, Hamada Y, Horii I.

J Toxicol Sci. 2006 Dec;31(5):419-32.PMID: 17202758 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: toxicity differentiation in hepatotoxicants.

Yamamoto T, Kikkawa R, Yamada H, Horii I.

J Toxicol Sci. 2006 Feb;31(1):49-60.PMID: 16538043 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo hepatotoxicity study of rats in comparison with in vitro hepatotoxicity screening system.

Kikkawa R, Fujikawa M, Yamamoto T, Hamada Y, Yamada H, Horii I.

J Toxicol Sci. 2006 Feb;31(1):23-34.PMID: 16538041 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of oxidative stress-related proteins for predictive screening of hepatotoxicity using a proteomic approach.

Yamamoto T, Kikkawa R, Yamada H, Horii I.

J Toxicol Sci. 2005 Aug;30(3):213-27.PMID: 16141655 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of male reproductive toxicants on gene expression in rat testes.

Fukushima T, Yamamoto T, Kikkawa R, Hamada Y, Komiyama M, Mori C, Horii I.

J Toxicol Sci. 2005 Aug;30(3):195-206.PMID: 16141653 [PubMed - indexed for MEDLINE]Related articlesFree article

MAPK/AP-1-dependent regulation of PAI-1 gene expression by TGF-beta in rat mesangial cells.

Guo B, Inoki K, Isono M, Mori H, Kanasaki K, Sugimoto T, Akiba S, Sato T, Yang B, Kikkawa R, Kashiwagi A, Haneda M, Koya D.

Kidney Int. 2005 Sep;68(3):972-84.PMID: 16105028 [PubMed - indexed for MEDLINE]Related articles

Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.

Maeda S, Tsukada S, Kanazawa A, Sekine A, Tsunoda T, Koya D, Maegawa H, Kashiwagi A, Babazono T, Matsuda M, Tanaka Y, Fujioka T, Hirose H, Eguchi T, Ohno Y, Groves CJ, Hattersley AT, Hitman GA, Walker M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Kamatani N, McCarthy MI, Nakamura Y.

J Hum Genet. 2005;50(6):283-92. Epub 2005 Jun 7.PMID: 15940393 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.

Kanazawa A, Kawamura Y, Sekine A, Iida A, Tsunoda T, Kashiwagi A, Tanaka Y, Babazono T, Matsuda M, Kawai K, Iiizumi T, Fujioka T, Imanishi M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S.

Diabetologia. 2005 Jul;48(7):1315-22. Epub 2005 Jun 4.PMID: 15937668 [PubMed - indexed for MEDLINE]Related articles

Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants.

Yamamoto T, Fukushima T, Kikkawa R, Yamada H, Horii I.

J Toxicol Sci. 2005 May;30(2):111-26.PMID: 15928459 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of a hepatotoxicity screening system in primary cell cultures --"what biomarkers would need to be addressed to estimate toxicity in conventional and new approaches?".

Kikkawa R, Yamamoto T, Fukushima T, Yamada H, Horii I.

J Toxicol Sci. 2005 Feb;30(1):61-72.PMID: 15800402 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.

Shimazaki A, Kawamura Y, Kanazawa A, Sekine A, Saito S, Tsunoda T, Koya D, Babazono T, Tanaka Y, Matsuda M, Kawai K, Iiizumi T, Imanishi M, Shinosaki T, Yanagimoto T, Ikeda M, Omachi S, Kashiwagi A, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakajima M, Nakamura Y, Maeda S.

Diabetes. 2005 Apr;54(4):1171-8.PMID: 15793258 [PubMed - indexed for MEDLINE]Related articlesFree article

Successful recovery of infective endocarditis-induced rapidly progressive glomerulonephritis by steroid therapy combined with antibiotics: a case report.

Koya D, Shibuya K, Kikkawa R, Haneda M.

BMC Nephrol. 2004 Dec 21;5(1):18.PMID: 15610562 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.

Kanazawa A, Tsukada S, Sekine A, Tsunoda T, Takahashi A, Kashiwagi A, Tanaka Y, Babazono T, Matsuda M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S.

Am J Hum Genet. 2004 Nov;75(5):832-43. Epub 2004 Sep 21.PMID: 15386214 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiproteinuric effect of candesartan cilexetil in Japanese subjects with type 2 diabetes and nephropathy.

Haneda M, Kikkawa R, Sakai H, Kawamori R; Candesartan in Diabetic Nephropathy Study Group.

Diabetes Res Clin Pract. 2004 Oct;66(1):87-95.PMID: 15364166 [PubMed - indexed for MEDLINE]Related articles

Characteristics of pancreas transplantation currently performed in japan.

Ishibashi M, Ito T, Sugitani A, Nakajima K, Abe T, Matsuno N, Hirao Y, Gotoh M, Tanaka M, Teraoka S, Matsuda H, Taniguchi H, Fukao T, Kikkawa R, Idezuki Y, Kanazawa Y.

Transplant Proc. 2004 May;36(4):1086-9.PMID: 15194378 [PubMed - indexed for MEDLINE]Related articles

A simple and sensitive method for glutamine:fructose-6-phosphate amidotransferase assay.

Ye F, Maegawa H, Morino K, Kashiwagi A, Kikkawa R, Xie M, Shen Z.

J Biochem Biophys Methods. 2004 Jun 30;59(3):201-8.PMID: 15165751 [PubMed - indexed for MEDLINE]Related articles

Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.

Tanaka N, Babazono T, Saito S, Sekine A, Tsunoda T, Haneda M, Tanaka Y, Fujioka T, Kaku K, Kawamori R, Kikkawa R, Iwamoto Y, Nakamura Y, Maeda S.

Diabetes. 2003 Nov;52(11):2848-53.PMID: 14578305 [PubMed - indexed for MEDLINE]Related articlesFree article

[Diabetic nephropathy--progress in its preclinical and clinical studies]

Kikkawa R, Koya D, Haneda M.

Nippon Naika Gakkai Zasshi. 2003 Sep 10;92(9):1650-61. Review. Japanese. No abstract available. PMID: 14560599 [PubMed - indexed for MEDLINE]Related articles

[18F]Fluorodeoxyglucose positron emission tomography surveillance of hepatic metastases from prostate cancer following radiofrequency ablation: a case report.

Ludwig V, Hopper OW, Martin WH, Kikkawa R, Delbeke D.

Am Surg. 2003 Jul;69(7):593-8.PMID: 12889623 [PubMed - indexed for MEDLINE]Related articles

APOE polymorphism and the progression of diabetic nephropathy in Japanese subjects with type 2 diabetes: results of a prospective observational follow-up study.

Araki S, Koya D, Makiishi T, Sugimoto T, Isono M, Kikkawa R, Kashiwagi A, Haneda M.

Diabetes Care. 2003 Aug;26(8):2416-20.PMID: 12882872 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats.

Koya D, Hayashi K, Kitada M, Kashiwagi A, Kikkawa R, Haneda M.

J Am Soc Nephrol. 2003 Aug;14(8 Suppl 3):S250-3.PMID: 12874441 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of Src kinase in platelet-derived growth factor-B-dependent tubular regeneration after acute ischemic renal injury.

Takikita-Suzuki M, Haneda M, Sasahara M, Owada MK, Nakagawa T, Isono M, Takikita S, Koya D, Ogasawara K, Kikkawa R.

Am J Pathol. 2003 Jul;163(1):277-86.PMID: 12819032 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetic neuropathy and nerve regeneration.

Yasuda H, Terada M, Maeda K, Kogawa S, Sanada M, Haneda M, Kashiwagi A, Kikkawa R.

Prog Neurobiol. 2003 Mar;69(4):229-85. Review.PMID: 12757748 [PubMed - indexed for MEDLINE]Related articles

Overview of glucose signaling in mesangial cells in diabetic nephropathy.

Haneda M, Koya D, Isono M, Kikkawa R.

J Am Soc Nephrol. 2003 May;14(5):1374-82. Review. No abstract available. PMID: 12707407 [PubMed - indexed for MEDLINE]Related articlesFree article

Progression of diabetic nephropathy.

Kikkawa R, Koya D, Haneda M.

Am J Kidney Dis. 2003 Mar;41(3 Suppl 1):S19-21. Review.PMID: 12612945 [PubMed - indexed for MEDLINE]Related articles

Antiproteinuric effect of candesartan cilexetil in patients with chronic glomerulonephritis.

Kurokawa K, Abe K, Saruta T, Arakawa M, Kikkawa R, Ueda N, Onoyama K, Tomita K, Ogawa N.

J Renin Angiotensin Aldosterone Syst. 2002 Sep;3(3):167-75.PMID: 12563567 [PubMed - indexed for MEDLINE]Related articles

[History of nephrology in the last 100 years: Diabetic nephropathies]

Kikkawa R.

Nippon Naika Gakkai Zasshi. 2002 May 10;91(5):1489-91. Review. Japanese. No abstract available. PMID: 12082740 [PubMed - indexed for MEDLINE]Related articles

15-Deoxy-Delta12,14-prostaglandin J2 inhibits IL-1beta-induced cyclooxygenase-2 expression in mesangial cells.

Sawano H, Haneda M, Sugimoto T, Inoki K, Koya D, Kikkawa R.

Kidney Int. 2002 Jun;61(6):1957-67.PMID: 12028436 [PubMed - indexed for MEDLINE]Related articlesFree article

A new approach of direct sample-digestion before vaporization for determination of a metal in rocks by inductively coupled plasma atomic emission spectrometry.

Okamoto Y, Kikkawa R, Fujiwara T.

Anal Sci. 2001 Apr;17(4):523-6.PMID: 11990570 [PubMed]Related articlesFree article

Increase in intracellular Ca(2+) and calcitonin gene-related peptide release through metabotropic P2Y receptors in rat dorsal root ganglion neurons.

Sanada M, Yasuda H, Omatsu-Kanbe M, Sango K, Isono T, Matsuura H, Kikkawa R.

Neuroscience. 2002;111(2):413-22.PMID: 11983326 [PubMed - indexed for MEDLINE]Related articles

Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulin.

Kojima H, Nakamura T, Fujita Y, Kishi A, Fujimiya M, Yamada S, Kudo M, Nishio Y, Maegawa H, Haneda M, Yasuda H, Kojima I, Seno M, Wong NC, Kikkawa R, Kashiwagi A.

Diabetes. 2002 May;51(5):1398-408.PMID: 11978636 [PubMed - indexed for MEDLINE]Related articlesFree article

Amelioration of high fructose-induced metabolic derangements by activation of PPARalpha.

Nagai Y, Nishio Y, Nakamura T, Maegawa H, Kikkawa R, Kashiwagi A.

Am J Physiol Endocrinol Metab. 2002 May;282(5):E1180-90.PMID: 11934685 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclic AMP inhibits stretch-induced overexpression of fibronectin in glomerular mesangial cells.

Nishio T, Haneda M, Koya D, Inoki K, Maeda S, Kikkawa R.

Eur J Pharmacol. 2002 Feb 22;437(3):113-22.PMID: 11890898 [PubMed - indexed for MEDLINE]Related articles

Reduced activity of mtTFA decreases the transcription in mitochondria isolated from diabetic rat heart.

Kanazawa A, Nishio Y, Kashiwagi A, Inagaki H, Kikkawa R, Horiike K.

Am J Physiol Endocrinol Metab. 2002 Apr;282(4):E778-85.PMID: 11882497 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of captopril or imidapril on the progression of diabetic nephropathy in Japanese with type 1 diabetes mellitus: a randomized controlled study (JAPAN-IDDM).

Katayama S, Kikkawa R, Isogai S, Sasaki N, Matsuura N, Tajima N, Urakami T, Uchigata Y, Ohashi Y.

Diabetes Res Clin Pract. 2002 Feb;55(2):113-21. Erratum in: Diabetes Res Clin Pract 2002 Jul;57(1):71. PMID: 11796177 [PubMed - indexed for MEDLINE]Related articles

Association of the DD genotype and development of Japanese type 2 diabetic nephropathy.

Gohda T, Makita Y, Shike T, Kobayashi M, Funabiki K, Haneda M, Kikkawa R, Watanabe T, Baba T, Yoshida H, Tomino Y.

Clin Nephrol. 2001 Dec;56(6):475-80.PMID: 11770799 [PubMed - indexed for MEDLINE]Related articles

Coronary endothelial dysfunction in the insulin-resistant state is linked to abnormal pteridine metabolism and vascular oxidative stress.

Shinozaki K, Hirayama A, Nishio Y, Yoshida Y, Ohtani T, Okamura T, Masada M, Kikkawa R, Kodama K, Kashiwagi A.

J Am Coll Cardiol. 2001 Dec;38(7):1821-8.PMID: 11738280 [PubMed - indexed for MEDLINE]Related articles

Increased arterial wall stiffness limits flow volume in the lower extremities in type 2 diabetic patients.

Suzuki E, Kashiwagi A, Nishio Y, Egawa K, Shimizu S, Maegawa H, Haneda M, Yasuda H, Morikawa S, Inubushi T, Kikkawa R.

Diabetes Care. 2001 Dec;24(12):2107-14.PMID: 11723092 [PubMed - indexed for MEDLINE]Related articlesFree article

Mesangial cell dysfunction as a pathogenesis of diabetic nephropathy.

Haneda M, Koya D, Kikkawa R.

Contrib Nephrol. 2001;(134):16-29. Review. No abstract available. PMID: 11665284 [PubMed - indexed for MEDLINE]Related articles

Cellular mechanisms in the development and progression of diabetic nephropathy: activation of the DAG-PKC-ERK pathway.

Haneda M, Koya D, Kikkawa R.

Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S178-81.PMID: 11576950 [PubMed - indexed for MEDLINE]Related articles

Dinucleotide repeat polymorphism of matrix metalloproteinase-9 gene is associated with diabetic nephropathy.

Maeda S, Haneda M, Guo B, Koya D, Hayashi K, Sugimoto T, Isshiki K, Yasuda H, Kashiwagi A, Kikkawa R.

Kidney Int. 2001 Oct;60(4):1428-34.PMID: 11576356 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study.

Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group.

Diabetes Care. 2001 Oct;24(10):1776-82. Erratum in: Diabetes Care 2002 Feb;25(2):413-4. PMID: 11574441 [PubMed - indexed for MEDLINE]Related articlesFree article

[Interstitial nephritis after treatment with mesalazine in the patient with ulcerative colitis]

Maeda S, Nomura S, Tahara M, Haneda M, Kikkawa R.

Nippon Naika Gakkai Zasshi. 2001 May 10;90(5):872-3. Japanese. No abstract available. PMID: 11460356 [PubMed - indexed for MEDLINE]Related articles