PubMed

Steroid 5-{alpha}-Reductase Type 2 (SRD5a2) Gene Polymorphisms and Risk of Prostate Cancer: A HuGE Review.

Li J, Coates RJ, Gwinn M, Khoury MJ.

Am J Epidemiol. 2009 Nov 13. [Epub ahead of print]PMID: 19914946 [PubMed - as supplied by publisher]Related articles

Phenopedia and Genopedia: Disease-centered and Gene-centered Views of the Evolving Knowledge of Human Genetic Associations.

Yu W, Clyne M, Khoury MJ, Gwinn M.

Bioinformatics. 2009 Oct 30. [Epub ahead of print]PMID: 19864262 [PubMed - as supplied by publisher]Related articlesFree article

Comparative effectiveness research and genomic medicine: an evolving partnership for 21st century medicine.

Khoury MJ, Rich EC, Randhawa G, Teutsch SM, Niederhuber J.

Genet Med. 2009 Oct;11(10):707-11.PMID: 19752739 [PubMed - in process]Related articles

Health care provider and consumer awareness, perceptions, and use of direct-to-consumer personal genomic tests, United States, 2008.

Kolor K, Liu T, St Pierre J, Khoury MJ.

Genet Med. 2009 Aug;11(8):595. No abstract available. PMID: 19680046 [PubMed - in process]Related articles

Invited commentary: genes, environment, and hybrid vigor.

Gwinn M, Guessous I, Khoury MJ.

Am J Epidemiol. 2009 Sep 15;170(6):703-7. Epub 2009 Aug 11.PMID: 19671836 [PubMed - indexed for MEDLINE]Related articles

Systems-based candidate genes for human response to influenza infection.

Zhang L, Katz JM, Gwinn M, Dowling NF, Khoury MJ.

Infect Genet Evol. 2009 Jul 30. [Epub ahead of print]PMID: 19647099 [PubMed - as supplied by publisher]Related articles

Personal utility and genomic information: look before you leap.

Grosse SD, McBride CM, Evans JP, Khoury MJ.

Genet Med. 2009 Aug;11(8):575-6. No abstract available. PMID: 19623080 [PubMed - in process]Related articles

The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop.

Khoury MJ, McBride CM, Schully SD, Ioannidis JP, Feero WG, Janssens AC, Gwinn M, Simons-Morton DG, Bernhardt JM, Cargill M, Chanock SJ, Church GM, Coates RJ, Collins FS, Croyle RT, Davis BR, Downing GJ, Duross A, Friedman S, Gail MH, Ginsburg GS, Green RC, Greene MH, Greenland P, Gulcher JR, Hsu A, Hudson KL, Kardia SL, Kimmel PL, Lauer MS, Miller AM, Offit K, Ransohoff DF, Roberts JS, Rasooly RS, Stefansson K, Terry SF, Teutsch SM, Trepanier A, Wanke KL, Witte JS, Xu J.

Genet Med. 2009 Aug;11(8):559-67.PMID: 19617843 [PubMed - in process]Related articles

Population Screening for Genetic Disorders in the 21st Century: Evidence, Economics, and Ethics.

Grosse SD, Rogowski WH, Ross LF, Cornel MC, Dondorp WJ, Khoury MJ.

Public Health Genomics. 2009 Jun 29. [Epub ahead of print]PMID: 19556749 [PubMed - as supplied by publisher]Related articles

Challenges of translating genetic tests into clinical and public health practice.

Rogowski WH, Grosse SD, Khoury MJ.

Nat Rev Genet. 2009 Jul;10(7):489-95. Review.PMID: 19506575 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases.

Khoury MJ, Bertram L, Boffetta P, Butterworth AS, Chanock SJ, Dolan SM, Fortier I, Garcia-Closas M, Gwinn M, Higgins JP, Janssens AC, Ostell J, Owen RP, Pagon RA, Rebbeck TR, Rothman N, Bernstein JL, Burton PR, Campbell H, Chockalingam A, Furberg H, Little J, O'Brien TR, Seminara D, Vineis P, Winn DM, Yu W, Ioannidis JP.

Am J Epidemiol. 2009 Aug 1;170(3):269-79. Epub 2009 Jun 4.PMID: 19498075 [PubMed - indexed for MEDLINE]Related articlesFree article

The genomic applications in practice and prevention network.

Khoury MJ, Feero WG, Reyes M, Citrin T, Freedman A, Leonard D, Burke W, Coates R, Croyle RT, Edwards K, Kardia S, McBride C, Manolio T, Randhawa G, Rasooly R, St Pierre J, Terry S; GAPPNet Planning Group.

Genet Med. 2009 Jul;11(7):488-94.PMID: 19471162 [PubMed - indexed for MEDLINE]Related articlesFree article

The association between family history of asthma and the prevalence of asthma among US adults: National Health and Nutrition Examination Survey, 1999-2004.

Liu T, Valdez R, Yoon PW, Crocker D, Moonesinghe R, Khoury MJ.

Genet Med. 2009 May;11(5):323-8.PMID: 19452621 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association studies in pharmacogenomics: untapped potential for translation.

Guessous I, Gwinn M, Khoury MJ.

Genome Med. 2009 Apr 28;1(4):46.PMID: 19439031 [PubMed - in process]Related articlesFree article

An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses.

Janssens AC, González-Zuloeta Ladd AM, López-Léon S, Ioannidis JP, Oostra BA, Khoury MJ, van Duijn CM.

Genet Med. 2009 Mar;11(3):153-62.PMID: 19367188 [PubMed - indexed for MEDLINE]Related articles

A health services research agenda for cellular, molecular and genomic technologies in cancer care.

Wideroff L, Phillips KA, Randhawa G, Ambs A, Armstrong K, Bennett CL, Brown ML, Donaldson MS, Follen M, Goldie SJ, Hiatt RA, Khoury MJ, Lewis G, McLeod HL, Piper M, Powell I, Schrag D, Schulman KA, Scott J.

Public Health Genomics. 2009;12(4):233-44. Epub 2009 Feb 20. Review.PMID: 19367091 [PubMed - indexed for MEDLINE]Related articles

The need for genetic variant naming standards in published abstracts of human genetic association studies.

Yu W, Ned R, Wulf A, Liu T, Khoury MJ, Gwinn M.

BMC Res Notes. 2009 Apr 14;2:56.PMID: 19366450 [PubMed - in process]Related articlesFree article

Family History as a Risk Factor for Early-Onset Stroke/Transient Ischemic Attack among Adults in the United States.

Mvundura M, McGruder H, Khoury MJ, Valdez R, Yoon PW.

Public Health Genomics. 2009 Mar 23. [Epub ahead of print]PMID: 19307734 [PubMed - as supplied by publisher]Related articles

STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N.

Eur J Clin Invest. 2009 Apr;39(4):247-66.PMID: 19297801 [PubMed - indexed for MEDLINE]Related articlesFree article

STrengthening the REporting of Genetic Association Studies (STREGA)--an extension of the STROBE statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N.

Genet Epidemiol. 2009 Nov;33(7):581-98.PMID: 19278015 [PubMed - in process]Related articles

Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart AF, Birkett N.

J Clin Epidemiol. 2009 Jun;62(6):597-608.e4. Epub 2009 Feb 12.PMID: 19217256 [PubMed - indexed for MEDLINE]Related articles

Trends in pharmacogenomic epidemiology: 2001-2007.

Guessous I, Gwinn M, Yu W, Yeh J, Clyne M, Khoury MJ.

Public Health Genomics. 2009;12(3):142-8. Epub 2009 Feb 10.PMID: 19204416 [PubMed - indexed for MEDLINE]Related articles

STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N; STrengthening the REporting of Genetic Association Studies.

PLoS Med. 2009 Feb 3;6(2):e22.PMID: 19192942 [PubMed - indexed for MEDLINE]Related articlesFree article

STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N.

Ann Intern Med. 2009 Feb 3;150(3):206-15.PMID: 19189911 [PubMed - indexed for MEDLINE]Related articlesFree article

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N.

Eur J Epidemiol. 2009;24(1):37-55. Epub 2009 Feb 3. Review.PMID: 19189221 [PubMed - indexed for MEDLINE]Related articlesFree article

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement.

Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N.

Hum Genet. 2009 Mar;125(2):131-51. Epub 2009 Feb 1.PMID: 19184668 [PubMed - indexed for MEDLINE]Related articles

Building a knowledge base on genetic variation and cancer risk through field synopses.

Yesupriya A, Gwinn M, Khoury MJ.

J Natl Cancer Inst. 2009 Jan 7;101(1):4-5. Epub 2008 Dec 30. No abstract available. PMID: 19116390 [PubMed - indexed for MEDLINE]Related articles

Public awareness and use of direct-to-consumer genetic tests: results from 3 state population-based surveys, 2006.

Goddard KA, Duquette D, Zlot A, Johnson J, Annis-Emeott A, Lee PW, Bland MP, Edwards KL, Oehlke K, Giles RT, Rafferty A, Cook ML, Khoury MJ.

Am J Public Health. 2009 Mar;99(3):442-5. Epub 2008 Dec 23.PMID: 19106425 [PubMed - indexed for MEDLINE]Related articles

Developing Family Healthware, a family history screening tool to prevent common chronic diseases.

Yoon PW, Scheuner MT, Jorgensen C, Khoury MJ.

Prev Chronic Dis. 2009 Jan;6(1):A33. Epub 2008 Dec 15.PMID: 19080039 [PubMed - indexed for MEDLINE]Related articlesFree article

Public health genomics: translating obesity genomics research into population health benefits.

Agurs-Collins T, Khoury MJ, Simon-Morton D, Olster DH, Harris JR, Milner JA.

Obesity (Silver Spring). 2008 Dec;16 Suppl 3:S85-94.PMID: 19037221 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene Prospector: an evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseases.

Yu W, Wulf A, Liu T, Khoury MJ, Gwinn M.

BMC Bioinformatics. 2008 Dec 8;9:528.PMID: 19063745 [PubMed - indexed for MEDLINE]Related articlesFree article

Sample size requirements to detect the effect of a group of genetic variants in case-control studies.

Moonesinghe R, Yang Q, Khoury MJ.

Emerg Themes Epidemiol. 2008 Dec 3;5:24.PMID: 19055767 [PubMed - in process]Related articlesFree article

Health-related direct-to-consumer genetic tests: a public health assessment and analysis of practices related to Internet-based tests for risk of thrombosis.

Goddard KA, Robitaille J, Dowling NF, Parrado AR, Fishman J, Bradley LA, Moore CA, Khoury MJ.

Public Health Genomics. 2009;12(2):92-104. Epub 2008 Nov 26.PMID: 19039253 [PubMed - indexed for MEDLINE]Related articles

A Decade of Public Health Genomics in the United States: Centers for Disease Control and Prevention 1997-2007.

Khoury MJ, Bowen S, Bradley LA, Coates R, Dowling NF, Gwinn M, Kolor K, Moore CA, St Pierre J, Valdez R, Yoon PW.

Public Health Genomics. 2008 Sep 3. [Epub ahead of print]PMID: 19023187 [PubMed - as supplied by publisher]Related articles

Invited commentary: from genome-wide association studies to gene-environment-wide interaction studies--challenges and opportunities.

Khoury MJ, Wacholder S.

Am J Epidemiol. 2009 Jan 15;169(2):227-30; discussion 234-5. Epub 2008 Nov 20.PMID: 19022826 [PubMed - indexed for MEDLINE]Related articles

The evidence dilemma in genomic medicine.

Khoury MJ, Berg A, Coates R, Evans J, Teutsch SM, Bradley LA.

Health Aff (Millwood). 2008 Nov-Dec;27(6):1600-11.PMID: 18997217 [PubMed - indexed for MEDLINE]Related articles

Public health genomics approach to type 2 diabetes.

Khoury MJ, Valdez R, Albright A.

Diabetes. 2008 Nov;57(11):2911-4. No abstract available. PMID: 18971439 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.

Chang MH, Lindegren ML, Butler MA, Chanock SJ, Dowling NF, Gallagher M, Moonesinghe R, Moore CA, Ned RM, Reichler MR, Sanders CL, Welch R, Yesupriya A, Khoury MJ; CDC/NCI NHANES III Genomics Working Group.

Am J Epidemiol. 2009 Jan 1;169(1):54-66. Epub 2008 Oct 20.PMID: 18936436 [PubMed - indexed for MEDLINE]Related articlesFree article

Why should genomic medicine become more evidence-based?

Khoury MJ, Bradley LA.

Genomic Med. 2007;1(3-4):91-3. Epub 2007 Dec 25. No abstract available. PMID: 18923933 [PubMed - in process]Related articlesFree article

Evaluation of the potential excess of statistically significant findings in published genetic association studies: application to Alzheimer's disease.

Kavvoura FK, McQueen MB, Khoury MJ, Tanzi RE, Bertram L, Ioannidis JP.

Am J Epidemiol. 2008 Oct 15;168(8):855-65. Epub 2008 Sep 8.PMID: 18779388 [PubMed - indexed for MEDLINE]Related articlesFree article

Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology.

Burton PR, Hansell AL, Fortier I, Manolio TA, Khoury MJ, Little J, Elliott P.

Int J Epidemiol. 2009 Feb;38(1):263-73. Epub 2008 Aug 1.PMID: 18676414 [PubMed - indexed for MEDLINE]Related articlesFree article

The continued need to synthesize the results of genetic associations across multiple studies.

Yesupriya A, Yu W, Clyne M, Gwinn M, Khoury MJ.

Genet Med. 2008 Aug;10(8):633-5. No abstract available. PMID: 18641511 [PubMed - indexed for MEDLINE]Related articles

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.

Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L.

Nat Genet. 2008 Jul;40(7):827-34.PMID: 18583979 [PubMed - indexed for MEDLINE]Related articles

Five genetic variants associated with prostate cancer.

Coates RJ, Khoury MJ, Gwinn M.

N Engl J Med. 2008 Jun 19;358(25):2738; author reply 2741. No abstract available. PMID: 18565871 [PubMed - indexed for MEDLINE]Related articles

Prevalence, family history, and prevention of reported osteoporosis in U.S. women.

Robitaille J, Yoon PW, Moore CA, Liu T, Irizarry-Delacruz M, Looker AC, Khoury MJ.

Am J Prev Med. 2008 Jul;35(1):47-54.PMID: 18541176 [PubMed - indexed for MEDLINE]Related articles

Reporting of human genome epidemiology (HuGE) association studies: an empirical assessment.

Yesupriya A, Evangelou E, Kavvoura FK, Patsopoulos NA, Clyne M, Walsh MC, Lin BK, Yu W, Gwinn M, Ioannidis JP, Khoury MJ.

BMC Med Res Methodol. 2008 May 20;8:31. Review.PMID: 18492284 [PubMed - indexed for MEDLINE]Related articlesFree article

HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real time.

Yu W, Wulf A, Yesupriya A, Clyne M, Khoury MJ, Gwinn M.

Eur J Hum Genet. 2008 Sep;16(9):1155-8. Epub 2008 May 14.PMID: 18478035 [PubMed - indexed for MEDLINE]Related articlesFree article

GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique.

Yu W, Clyne M, Dolan SM, Yesupriya A, Wulf A, Liu T, Khoury MJ, Gwinn M.

BMC Bioinformatics. 2008 Apr 22;9:205.PMID: 18430222 [PubMed - indexed for MEDLINE]Related articlesFree article

A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions.

Janssens AC, Gwinn M, Bradley LA, Oostra BA, van Duijn CM, Khoury MJ.

Am J Hum Genet. 2008 Mar;82(3):593-9.PMID: 18319070 [PubMed - indexed for MEDLINE]Related articlesFree article

A navigator for human genome epidemiology.

Yu W, Gwinn M, Clyne M, Yesupriya A, Khoury MJ.

Nat Genet. 2008 Feb;40(2):124-5. No abstract available. PMID: 18227866 [PubMed - indexed for MEDLINE]Related articles