PubMed

Performance during constant workrate cycling exercise in women with COPD and hyperinflation.

Laviolette L, O'Donnell DE, Webb KA, Hamilton AL, Kesten S, Maltais F.

COPD. 2009 Oct;6(5):340-51.PMID: 19863363 [PubMed - in process]Related articles

Therapeutic conversion of the combination of ipratropium and albuterol to tiotropium in patients with chronic obstructive pulmonary disease.

Niewoehner DE, Lapidus R, Cote C, Sharafkhaneh A, Plautz M, Johnson P, Kesten S.

Pulm Pharmacol Ther. 2009 Dec;22(6):587-92. Epub 2009 Sep 6.PMID: 19737620 [PubMed - in process]Related articles

Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease.

Celli B, Decramer M, Kesten S, Liu D, Mehra S, Tashkin DP; UPLIFT Study Investigators.

Am J Respir Crit Care Med. 2009 Nov 15;180(10):948-55. Epub 2009 Sep 3.PMID: 19729663 [PubMed - in process]Related articles

Long-term efficacy of tiotropium in relation to smoking status in the UPLIFT trial.

Tashkin DP, Celli B, Kesten S, Lystig T, Mehra S, Decramer M.

Eur Respir J. 2009 Aug 28. [Epub ahead of print]PMID: 19717481 [PubMed - as supplied by publisher]Related articles

Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial.

Decramer M, Celli B, Kesten S, Lystig T, Mehra S, Tashkin DP; UPLIFT investigators.

Lancet. 2009 Oct 3;374(9696):1171-8. Epub 2009 Aug 27.PMID: 19716598 [PubMed - indexed for MEDLINE]Related articles

Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes.

Anzueto A, Leimer I, Kesten S.

Int J Chron Obstruct Pulmon Dis. 2009;4(2):245-51. Epub 2009 Jul 20.PMID: 19657398 [PubMed - in process]Related articlesFree article

Cardiovascular Safety of Tiotropium in Patients With COPD.

Celli B, Decramer M, Leimer I, Vogel U, Kesten S, Tashkin DP.

Chest. 2009 Jul 10. [Epub ahead of print]PMID: 19592475 [PubMed - as supplied by publisher]Related articles

Evaluation of withdrawal of maintenance tiotropium in COPD.

Adams SG, Anzueto A, Briggs DD Jr, Leimer I, Kesten S.

Respir Med. 2009 Oct;103(10):1415-20. Epub 2009 Jun 11.PMID: 19523796 [PubMed - in process]Related articles

Study design considerations in a large COPD trial comparing effects of tiotropium with salmeterol on exacerbations.

Beeh KM, Hederer B, Glaab T, Müller A, Moelken MR, Kesten S, Vogelmeier C.

Int J Chron Obstruct Pulmon Dis. 2009;4(1):119-25. Epub 2009 Apr 15.PMID: 19436693 [PubMed - in process]Related articlesFree article

Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH).

Johnson DS, Ahn K, Kesten S, Lazerwith SE, Song Y, Morris M, Fay L, Gregory T, Stiff C, Dunbar JB Jr, Liimatta M, Beidler D, Smith S, Nomanbhoy TK, Cravatt BF.

Bioorg Med Chem Lett. 2009 May 15;19(10):2865-9. Epub 2009 Mar 24.PMID: 19386497 [PubMed - indexed for MEDLINE]Related articles

Risk of major adverse cardiovascular events with inhaled anticholinergics in patients with chronic obstructive pulmonary disease.

Kesten S, Leimer I, Jara M.

JAMA. 2009 Mar 25;301(12):1224; author reply 1225-6. No abstract available. PMID: 19318648 [PubMed - indexed for MEDLINE]Related articles

Reliability of ventilatory parameters during cycle ergometry in multicentre trials in COPD.

O'Donnell DE, Travers J, Webb KA, He Z, Lam YM, Hamilton A, Kesten S, Maltais F, Magnussen H.

Eur Respir J. 2009 Oct;34(4):866-74. Epub 2009 Mar 12.PMID: 19282342 [PubMed - in process]Related articles

A 4-year trial of tiotropium in chronic obstructive pulmonary disease.

Tashkin DP, Celli B, Senn S, Burkhart D, Kesten S, Menjoge S, Decramer M; UPLIFT Study Investigators.

N Engl J Med. 2008 Oct 9;359(15):1543-54. Epub 2008 Oct 5.PMID: 18836213 [PubMed - indexed for MEDLINE]Related articlesFree article

Responses to tiotropium in African-American and Caucasian patients with chronic obstructive pulmonary disease.

Rice KL, Leimer I, Kesten S, Niewoehner DE.

Transl Res. 2008 Aug;152(2):88-94. Epub 2008 Jun 23.PMID: 18674743 [PubMed - indexed for MEDLINE]Related articles

Improvement in self-reported exercise participation with the combination of tiotropium and rehabilitative exercise training in COPD patients.

Kesten S, Casaburi R, Kukafka D, Cooper CB.

Int J Chron Obstruct Pulmon Dis. 2008;3(1):127-36.PMID: 18488436 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of tiotropium bromide and combined ipratropium/salbutamol for the treatment of COPD: a UK General Practice Research Database 12-month follow-up study.

Griffin J, Lee S, Caiado M, Kesten S, Price D.

Prim Care Respir J. 2008 Jun;17(2):104-10.PMID: 18385913 [PubMed - indexed for MEDLINE]Related articlesFree article

Bronchodilator responsiveness in patients with COPD.

Tashkin DP, Celli B, Decramer M, Liu D, Burkhart D, Cassino C, Kesten S.

Eur Respir J. 2008 Apr;31(4):742-50. Epub 2008 Feb 6.PMID: 18256071 [PubMed - indexed for MEDLINE]Related articlesFree article

Tiotropium and exercise training in COPD patients: effects on dyspnea and exercise tolerance.

Ambrosino N, Foglio K, Balzano G, Paggiaro PL, Lessi P, Kesten S; Tiotropium Multicentric Italian Study Group.

Int J Chron Obstruct Pulmon Dis. 2008;3(4):771-80.PMID: 19281092 [PubMed - indexed for MEDLINE]Related articlesFree article

Outcomes in COPD patients receiving tiotropium or salmeterol plus treatment with inhaled corticosteroids.

Hodder R, Kesten S, Menjoge S, Viel K.

Int J Chron Obstruct Pulmon Dis. 2007;2(2):157-67.PMID: 18044688 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative safety of long-acting inhaled bronchodilators: a cohort study using the UK THIN primary care database.

Jara M, Lanes SF, Wentworth C 3rd, May C, Kesten S.

Drug Saf. 2007;30(12):1151-60.PMID: 18035867 [PubMed - indexed for MEDLINE]Related articles

Improvements with tiotropium in COPD patients with concomitant asthma.

Magnussen H, Bugnas B, van Noord J, Schmidt P, Gerken F, Kesten S.

Respir Med. 2008 Jan;102(1):50-6. Epub 2007 Oct 24.PMID: 17920256 [PubMed - indexed for MEDLINE]Related articles

(1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.

Hu LY, Du D, Hoffman J, Smith Y, Fedij V, Kostlan C, Johnson TR, Huang Y, Kesten S, Harter W, Yue WS, Li JJ, Barvian N, Mitchell L, Lei HJ, Lefker B, Carroll M, Dettling D, Krieger-Burke T, Samas B, Yalamanchili R, Lapham K, Pocalyko D, Sliskovic D, Ciotti S, Stoller B, Hena MA, Ding Q, Maiti SN, Stier M, Welgus H.

Bioorg Med Chem Lett. 2007 Nov 1;17(21):5983-8. Epub 2007 Aug 21.PMID: 17827000 [PubMed - indexed for MEDLINE]Related articles

Premature discontinuation of patients: a potential bias in COPD clinical trials.

Kesten S, Plautz M, Piquette CA, Habib MP, Niewoehner DE.

Eur Respir J. 2007 Nov;30(5):898-906. Epub 2007 Aug 9. Erratum in: Eur Respir J. 2008 Jan;31(1):226. PMID: 17690120 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD.

Powrie DJ, Wilkinson TM, Donaldson GC, Jones P, Scrine K, Viel K, Kesten S, Wedzicha JA.

Eur Respir J. 2007 Sep;30(3):472-8. Epub 2007 May 15.PMID: 17504798 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of tiotropium bromide on the cardiovascular response to exercise in COPD.

Travers J, Laveneziana P, Webb KA, Kesten S, O'Donnell DE.

Respir Med. 2007 Sep;101(9):2017-24. Epub 2007 May 1.PMID: 17475459 [PubMed - indexed for MEDLINE]Related articles

Risk indexes for exacerbations and hospitalizations due to COPD.

Niewoehner DE, Lokhnygina Y, Rice K, Kuschner WG, Sharafkhaneh A, Sarosi GA, Krumpe P, Pieper K, Kesten S.

Chest. 2007 Jan;131(1):20-8.PMID: 17218552 [PubMed - indexed for MEDLINE]Related articlesFree article

Pooled clinical trial analysis of tiotropium safety.

Kesten S, Jara M, Wentworth C, Lanes S.

Chest. 2006 Dec;130(6):1695-703.PMID: 17166984 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical trial design considerations in assessing long-term functional impacts of tiotropium in COPD: the UPLIFT trial.

Decramer M, Celli B, Tashkin DP, Pauwels RA, Burkhart D, Cassino C, Kesten S.

COPD. 2004;1(2):303-12.PMID: 17136995 [PubMed - indexed for MEDLINE]Related articles

Eletrocardiographic monitoring in COPD patients receiving tiotropium.

Morganroth J, Golisch W, Kesten S.

COPD. 2004;1(2):181-90.PMID: 17136986 [PubMed - indexed for MEDLINE]Related articles

Tiotropium in COPD patients not previously receiving maintenance respiratory medications.

Adams SG, Anzueto A, Briggs DD Jr, Menjoge SS, Kesten S.

Respir Med. 2006 Sep;100(9):1495-503. Epub 2006 May 15.PMID: 16698259 [PubMed - indexed for MEDLINE]Related articles

Health outcomes following treatment for 6 months with once daily tiotropium compared with twice daily salmeterol in patients with COPD.

Brusasco V, Hodder R, Miravitlles M, Korducki L, Towse L, Kesten S.

Thorax. 2006 Jan;61(1):91. No abstract available. PMID: 16396956 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of electrocardiographic findings and improved function with once-daily tiotropium in patients with chronic obstructive pulmonary disease.

Covelli H, Bhattacharya S, Cassino C, Conoscenti C, Kesten S.

Pharmacotherapy. 2005 Dec;25(12):1708-18.PMID: 16305289 [PubMed - indexed for MEDLINE]Related articles

Improved daytime spirometric efficacy of tiotropium compared with salmeterol in patients with COPD.

Briggs DD Jr, Covelli H, Lapidus R, Bhattycharya S, Kesten S, Cassino C.

Pulm Pharmacol Ther. 2005;18(6):397-404. Epub 2005 Apr 25.PMID: 16179215 [PubMed - indexed for MEDLINE]Related articles

Improvements in symptom-limited exercise performance over 8 h with once-daily tiotropium in patients with COPD.

Maltais F, Hamilton A, Marciniuk D, Hernandez P, Sciurba FC, Richter K, Kesten S, O'Donnell D.

Chest. 2005 Sep;128(3):1168-78.PMID: 16162703 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial.

Niewoehner DE, Rice K, Cote C, Paulson D, Cooper JA Jr, Korducki L, Cassino C, Kesten S.

Ann Intern Med. 2005 Sep 6;143(5):317-26.PMID: 16144890 [PubMed - indexed for MEDLINE]Related articlesFree article

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.

Hu LY, Boxer PA, Kesten SR, Lei HJ, Wustrow DJ, Moreland DW, Zhang L, Ahn K, Ryder TR, Liu X, Rubin JR, Fahnoe K, Carroll RT, Dutta S, Fahnoe DC, Probert AW, Roof RL, Rafferty MF, Kostlan CR, Scholten JD, Hood M, Ren XD, Schielke GP, Su TZ, Taylor CP, Mistry A, McConnell P, Hasemann C, Ohren J.

Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6.PMID: 16143519 [PubMed - indexed for MEDLINE]Related articles

Improvement in exercise tolerance with the combination of tiotropium and pulmonary rehabilitation in patients with COPD.

Casaburi R, Kukafka D, Cooper CB, Witek TJ Jr, Kesten S.

Chest. 2005 Mar;127(3):809-17.PMID: 15764761 [PubMed - indexed for MEDLINE]Related articlesFree article

One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium.

Anzueto A, Tashkin D, Menjoge S, Kesten S.

Pulm Pharmacol Ther. 2005;18(2):75-81. Epub 2004 Dec 20.PMID: 15649848 [PubMed - indexed for MEDLINE]Related articles

Healthcare costs with tiotropium plus usual care versus usual care alone following 1 year of treatment in patients with chronic obstructive pulmonary disorder (COPD).

Friedman M, Menjoge SS, Anton SF, Kesten S.

Pharmacoeconomics. 2004;22(11):741-9.PMID: 15250751 [PubMed - indexed for MEDLINE]Related articles

Subtype selective NMDA receptor antagonists: evaluation of some novel alkynyl analogues.

Kornberg BE, Nikam SS, Wright JL, Kesten SR, Meltzer LT, Coughenour L, Barr B, Serpa KA, McCormick J.

Bioorg Med Chem Lett. 2004 Mar 8;14(5):1213-6.PMID: 14980668 [PubMed - indexed for MEDLINE]Related articles

Insurance status and patient behavior with asthma medications.

Stevens D, Sharma K, Kesten S.

J Asthma. 2003;40(7):789-93.PMID: 14626335 [PubMed - indexed for MEDLINE]Related articles

Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes.

Celli B, ZuWallack R, Wang S, Kesten S.

Chest. 2003 Nov;124(5):1743-8.PMID: 14605043 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of patient performance of the HandiHaler compared with the metered dose inhaler four weeks after instruction.

Dahl R, Backer V, Ollgaard B, Gerken F, Kesten S.

Respir Med. 2003 Oct;97(10):1126-33.PMID: 14561020 [PubMed - indexed for MEDLINE]Related articles

Tolerance to bronchodilating effects of salmeterol in COPD.

Donohue JF, Menjoge S, Kesten S.

Respir Med. 2003 Sep;97(9):1014-20.PMID: 14509555 [PubMed - indexed for MEDLINE]Related articles

Long-term treatment benefits with tiotropium in COPD patients with and without short-term bronchodilator responses.

Tashkin D, Kesten S.

Chest. 2003 May;123(5):1441-9.PMID: 12740259 [PubMed - indexed for MEDLINE]Related articlesFree article

Health outcomes following treatment for six months with once daily tiotropium compared with twice daily salmeterol in patients with COPD.

Brusasco V, Hodder R, Miravitlles M, Korducki L, Towse L, Kesten S.

Thorax. 2003 May;58(5):399-404. Erratum in: Thorax. 2005 Feb;60(2):105. PMID: 12728159 [PubMed - indexed for MEDLINE]Related articlesFree article

A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patients treated with tiotropium or salmeterol.

Donohue JF, van Noord JA, Bateman ED, Langley SJ, Lee A, Witek TJ Jr, Kesten S, Towse L.

Chest. 2002 Jul;122(1):47-55.PMID: 12114338 [PubMed - indexed for MEDLINE]Related articlesFree article

Noninvasive nocturnal ventilatory support in advanced lung disease from cystic fibrosis.

Granton JT, Shapiro C, Kesten S.

Respir Care. 2002 Jun;47(6):675-81.PMID: 12036437 [PubMed - indexed for MEDLINE]Related articles

Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium.

Vincken W, van Noord JA, Greefhorst AP, Bantje TA, Kesten S, Korducki L, Cornelissen PJ; Dutch/Belgian Tiotropium Study Group.

Eur Respir J. 2002 Feb;19(2):209-16.PMID: 11871363 [PubMed - indexed for MEDLINE]Related articlesFree article

Effective delivery of particles with the HandiHaler dry powder inhalation system over a range of chronic obstructive pulmonary disease severity.

Chodosh S, Flanders JS, Kesten S, Serby CW, Hochrainer D, Witek TJ Jr.

J Aerosol Med. 2001 Fall;14(3):309-15.PMID: 11693842 [PubMed - indexed for MEDLINE]Related articles