PubMed

Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney.

Dunbar DR, Khaled H, Evans LC, Al-Dujaili EA, Mullins LJ, Mullins JJ, Kenyon CJ, Bailey MA.

Physiol Genomics. 2009 Nov 17. [Epub ahead of print]PMID: 19920212 [PubMed - as supplied by publisher]Related articles

Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome.

Bailey MA, Mullins JJ, Kenyon CJ.

Hypertension. 2009 Oct;54(4):890-6. Epub 2009 Jul 27.PMID: 19635986 [PubMed - indexed for MEDLINE]Related articles

Physiological and pathophysiological applications of sensitive ELISA methods for urinary deoxycorticosterone and corticosterone in rodents.

Al-Dujaili EA, Mullins LJ, Bailey MA, Andrew R, Kenyon CJ.

Steroids. 2009 Nov;74(12):938-44. Epub 2009 Jul 3.PMID: 19577584 [PubMed - in process]Related articles

Angiotensin-converting enzyme is a modifier of hypertensive end organ damage.

Liu X, Bellamy CO, Bailey MA, Mullins LJ, Dunbar DR, Kenyon CJ, Brooker G, Kantachuvesiri S, Maratou K, Ashek A, Clark AF, Fleming S, Mullins JJ.

J Biol Chem. 2009 Jun 5;284(23):15564-72. Epub 2009 Mar 23.PMID: 19307186 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of a highly sensitive ELISA for aldosterone in mouse urine: validation in physiological and pathophysiological states of aldosterone excess and depletion.

Al-Dujaili EA, Mullins LJ, Bailey MA, Kenyon CJ.

Steroids. 2009 Apr-May;74(4-5):456-62. Epub 2008 Dec 31.PMID: 19162057 [PubMed - indexed for MEDLINE]Related articles

Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.

Mullins LJ, Peter A, Wrobel N, McNeilly JR, McNeilly AS, Al-Dujaili EA, Brownstein DG, Mullins JJ, Kenyon CJ.

J Biol Chem. 2009 Feb 6;284(6):3925-34. Epub 2008 Nov 24.PMID: 19029289 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.

Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE.

FASEB J. 2008 Nov;22(11):3896-907. Epub 2008 Aug 12.PMID: 18697839 [PubMed - indexed for MEDLINE]Related articlesFree article

Divergent physical activity and novel alternative responses to high fat feeding in polygenic fat and lean mice.

Simoncic M, Horvat S, Stevenson PL, Bünger L, Holmes MC, Kenyon CJ, Speakman JR, Morton NM.

Behav Genet. 2008 May;38(3):292-300. Epub 2008 Mar 18.PMID: 18347969 [PubMed - indexed for MEDLINE]Related articles

Prenatal dexamethasone 'programmes' hypotension, but stress-induced hypertension in adult offspring.

O'Regan D, Kenyon CJ, Seckl JR, Holmes MC.

J Endocrinol. 2008 Feb;196(2):343-52.PMID: 18252958 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of ACTH, dexamethasone, and adrenalectomy on 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) gene expression in the rat central nervous system.

Ye P, Kenyon CJ, Mackenzie SM, Nichol K, Seckl JR, Fraser R, Connell JM, Davies E.

J Endocrinol. 2008 Feb;196(2):305-11.PMID: 18252953 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone.

Michailidou Z, Coll AP, Kenyon CJ, Morton NM, O'Rahilly S, Seckl JR, Chapman KE.

J Endocrinol. 2007 Jul;194(1):161-70.PMID: 17592030 [PubMed - indexed for MEDLINE]Related articlesFree article

Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia.

Lai M, Horsburgh K, Bae SE, Carter RN, Stenvers DJ, Fowler JH, Yau JL, Gomez-Sanchez CE, Holmes MC, Kenyon CJ, Seckl JR, Macleod MR.

Eur J Neurosci. 2007 Mar;25(6):1832-42.PMID: 17432969 [PubMed - indexed for MEDLINE]Related articles

Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice.

Paterson JM, Holmes MC, Kenyon CJ, Carter R, Mullins JJ, Seckl JR.

Endocrinology. 2007 Mar;148(3):961-6. Epub 2006 Dec 14.PMID: 17170103 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.

O'Reilly M, Marshall E, Macgillivray T, Mittal M, Xue W, Kenyon CJ, Brown RW.

J Am Soc Nephrol. 2006 Sep;17(9):2402-13. Epub 2006 Aug 9.PMID: 16899520 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered vascular contractility in adult female rats with hypertension programmed by prenatal glucocorticoid exposure.

Hadoke PW, Lindsay RS, Seckl JR, Walker BR, Kenyon CJ.

J Endocrinol. 2006 Mar;188(3):435-42.PMID: 16522724 [PubMed - indexed for MEDLINE]Related articlesFree article

A polygenic model of the metabolic syndrome with reduced circulating and intra-adipose glucocorticoid action.

Morton NM, Densmore V, Wamil M, Ramage L, Nichol K, Bünger L, Seckl JR, Kenyon CJ.

Diabetes. 2005 Dec;54(12):3371-8.PMID: 16306351 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of aldosterone biosynthesis by staurosporine.

Bureik M, Mion A, Kenyon CJ, Bernhardt R.

Biol Chem. 2005 Jul;386(7):663-9.PMID: 16207087 [PubMed - indexed for MEDLINE]Related articles

DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. 1980.

Kenyon CJ, Walker GC.

DNA Repair (Amst). 2005 Aug 15;4(9):1049-53. No abstract available. PMID: 16196125 [PubMed - indexed for MEDLINE]Related articles

The aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) genes are not expressed in the rat heart.

Ye P, Kenyon CJ, MacKenzie SM, Jong AS, Miller C, Gray GA, Wallace A, Ryding AS, Mullins JJ, McBride MW, Graham D, Fraser R, Connell JM, Davies E.

Endocrinology. 2005 Dec;146(12):5287-93. Epub 2005 Sep 22.PMID: 16179417 [PubMed - indexed for MEDLINE]Related articlesFree article

The two isoforms of the Caenorhabditis elegans leukocyte-common antigen related receptor tyrosine phosphatase PTP-3 function independently in axon guidance and synapse formation.

Ackley BD, Harrington RJ, Hudson ML, Williams L, Kenyon CJ, Chisholm AD, Jin Y.

J Neurosci. 2005 Aug 17;25(33):7517-28.PMID: 16107639 [PubMed - indexed for MEDLINE]Related articlesFree article

Preventing local regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 enhances angiogenesis.

Small GR, Hadoke PW, Sharif I, Dover AR, Armour D, Kenyon CJ, Gray GA, Walker BR.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12165-70. Epub 2005 Aug 10.PMID: 16093320 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucocorticoid exposure in late gestation in the rat permanently programs gender-specific differences in adult cardiovascular and metabolic physiology.

O'Regan D, Kenyon CJ, Seckl JR, Holmes MC.

Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E863-70. Epub 2004 Jul 6.PMID: 15238353 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice.

Paterson JM, Morton NM, Fievet C, Kenyon CJ, Holmes MC, Staels B, Seckl JR, Mullins JJ.

Proc Natl Acad Sci U S A. 2004 May 4;101(18):7088-93. Epub 2004 Apr 26.PMID: 15118095 [PubMed - indexed for MEDLINE]Related articlesFree article

5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor.

McInnes KJ, Kenyon CJ, Chapman KE, Livingstone DE, Macdonald LJ, Walker BR, Andrew R.

J Biol Chem. 2004 May 28;279(22):22908-12. Epub 2004 Mar 24.PMID: 15044432 [PubMed - indexed for MEDLINE]Related articlesFree article

Déjà vu: angiotensin and stress.

Antoni FA, Kenyon CJ.

Trends Endocrinol Metab. 2003 Aug;14(6):249-50. Review. No abstract available. PMID: 12890582 [PubMed - indexed for MEDLINE]Related articles

Regulation of aldosterone synthase gene expression in the rat adrenal gland and central nervous system by sodium and angiotensin II.

Ye P, Kenyon CJ, MacKenzie SM, Seckl JR, Fraser R, Connell JM, Davies E.

Endocrinology. 2003 Aug;144(8):3321-8.PMID: 12865309 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice.

Masuzaki H, Yamamoto H, Kenyon CJ, Elmquist JK, Morton NM, Paterson JM, Shinyama H, Sharp MG, Fleming S, Mullins JJ, Seckl JR, Flier JS.

J Clin Invest. 2003 Jul;112(1):83-90.PMID: 12840062 [PubMed - indexed for MEDLINE]Related articlesFree article

CYP11B2 polymorphisms and cardiovascular risk factors.

Davies E, Kenyon CJ.

J Hypertens. 2003 Jul;21(7):1249-53. Review. No abstract available. PMID: 12817167 [PubMed - indexed for MEDLINE]Related articles

Mutations flanking the polyglutamine repeat in the modulatory domain of rat glucocorticoid receptor lead to an increase in affinity for hormone.

Heeley RP, Rusconi SG, Sutcliffe RG, Kenyon CJ.

Endocr Res. 2002 Aug;28(3):217-29.PMID: 12489571 [PubMed - indexed for MEDLINE]Related articles

Quantitative trait loci influencing blood and liver cholesterol concentration in rats.

Bonné AC, den Bieman MG, Gillissen GF, Lankhorst A, Kenyon CJ, van Zutphen BF, van Lith HA.

Arterioscler Thromb Vasc Biol. 2002 Dec 1;22(12):2072-9.PMID: 12482837 [PubMed - indexed for MEDLINE]Related articlesFree article

Mineralocorticoid-induced hypertension in obese Zucker rats.

Kenyon CJ.

J Hypertens. 2002 Nov;20(11):2151-2. Review. No abstract available. PMID: 12409951 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid receptor binding in twin pairs is affected by shared environment but not by shared genes.

Blackhurst G, McElroy KP, Kenyon CJ, Fraser R, Swan L, Anderson N, Hillis S, Connell JM.

J Steroid Biochem Mol Biol. 2002 Apr;80(4-5):395-400.PMID: 11983486 [PubMed - indexed for MEDLINE]Related articles

Mutations in aldosterone synthase gene of Milan hypertensive rats: phenotypic consequences.

Lloyd-MacGilp SA, Torielli L, Bechtel S, Tripodi G, Gomez-Sanchez CE, Zagato L, Bernhardt R, Kenyon CJ.

Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E608-17.PMID: 11832364 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11beta-hydroxysteroid dehydrogenase.

Hadoke PW, Christy C, Kotelevtsev YV, Williams BC, Kenyon CJ, Seckl JR, Mullins JJ, Walker BR.

Circulation. 2001 Dec 4;104(23):2832-7.PMID: 11733403 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments.

Yau JL, Noble J, Kenyon CJ, Hibberd C, Kotelevtsev Y, Mullins JJ, Seckl JR.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4716-21. Epub 2001 Mar 27.PMID: 11274359 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of dysregulation of 11 beta-hydroxysteroid dehydrogenase type 1 in obese Zucker rats.

Livingstone DE, Kenyon CJ, Walker BR.

J Endocrinol. 2000 Dec;167(3):533-9.PMID: 11115781 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the myocardial endothelin system by angiotensin-II and losartan.

McEwan PE, Sherry L, Kenyon CJ, Webb DJ, Gray GA.

J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S144-7.PMID: 11078361 [PubMed - indexed for MEDLINE]Related articles

Regulation of 11beta-hydroxysteroid dehydrogenase enzymes by dietary sodium in the rat.

McKinnell J, Roscoe D, Holmes MC, Lloyd-MacGilp SA, Kenyon CJ.

Endocr Res. 2000 Feb;26(1):81-95.PMID: 10711725 [PubMed - indexed for MEDLINE]Related articles

Gastrointestinal spread of oral prolonged-release mesalazine microgranules (Pentasa) dosed as either tablets or sachet.

Wilding IR, Kenyon CJ, Hooper G.

Aliment Pharmacol Ther. 2000 Feb;14(2):163-9.PMID: 10651656 [PubMed - indexed for MEDLINE]Related articlesFree article

Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats.

Livingstone DE, Jones GC, Smith K, Jamieson PM, Andrew R, Kenyon CJ, Walker BR.

Endocrinology. 2000 Feb;141(2):560-3.PMID: 10650936 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of angiotensin II on remodelling of the airway and the vasculature in the rat.

Ramsay SG, Kenyon CJ, Whyte N, McKay IC, Thomson NC, Lindop GB.

Clin Sci (Lond). 2000 Jan;98(1):1-7.PMID: 10600652 [PubMed - indexed for MEDLINE]Related articles

11beta-hydroxysteroid dehydrogenase and corticosteroid action in lyon hypertensive rats.

Lloyd-MacGilp SA, Nelson SM, Florin M, Lo M, McKinnell J, Sassard J, Kenyon CJ.

Hypertension. 1999 Nov;34(5):1123-8.PMID: 10567193 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of aldosterone secretion by benzodiazepines in bovine adrenocortical cells.

Kenyon CJ, Thomson I, Fraser R.

Fundam Clin Pharmacol. 1999;13(2):213-9.PMID: 10226766 [PubMed - indexed for MEDLINE]Related articles

Control of adrenal cell proliferation by AT1 receptors in response to angiotensin II and low-sodium diet.

McEwan PE, Vinson GP, Kenyon CJ.

Am J Physiol. 1999 Feb;276(2 Pt 1):E303-9.PMID: 9950790 [PubMed - indexed for MEDLINE]Related articlesFree article

StAR protein is expressed in both medulla and cortex of the bovine and rat adrenal gland.

Lo YC, Brett L, Kenyon CJ, Morley SD, Mason JI, Williams BC.

Endocr Res. 1998 Aug-Nov;24(3-4):559-63.PMID: 9888537 [PubMed - indexed for MEDLINE]Related articles

Differential effects of angiotensin II on cardiac cell proliferation and intramyocardial perivascular fibrosis in vivo.

McEwan PE, Gray GA, Sherry L, Webb DJ, Kenyon CJ.

Circulation. 1998 Dec 15;98(24):2765-73.PMID: 9851965 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucocorticoid receptor polymorphism in genetic hypertension.

Kenyon CJ, Panarelli M, Zagato L, Torielli L, Heeley RP, Holloway CD, Fraser R, Casari G, Sutcliffe RG, Bianchi G.

J Mol Endocrinol. 1998 Aug;21(1):41-50.PMID: 9723862 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucocorticoid receptor polymorphism, skin vasoconstriction, and other metabolic intermediate phenotypes in normal human subjects.

Panarelli M, Holloway CD, Fraser R, Connell JM, Ingram MC, Anderson NH, Kenyon CJ.

J Clin Endocrinol Metab. 1998 Jun;83(6):1846-52.PMID: 9626107 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring.

Nyirenda MJ, Lindsay RS, Kenyon CJ, Burchell A, Seckl JR.

J Clin Invest. 1998 May 15;101(10):2174-81.PMID: 9593773 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of static charge in spacer devices on glucocorticosteroid aerosol deposition in asthmatic patients.

Kenyon CJ, Thorsson L, Borgström L, Newman SP.

Eur Respir J. 1998 Mar;11(3):606-10.PMID: 9596110 [PubMed - indexed for MEDLINE]Related articlesFree article