PubMed

Trends in rates of retinal surgery in England from 1968 to 2004: studies of hospital statistics.

El-Amir AN, Keenan TD, Abu-Bakra M, Tanner V, Yeates D, Goldacre MJ.

Br J Ophthalmol. 2009 Dec;93(12):1585-1590. Epub 2009 Aug 10.PMID: 19671530 [PubMed - as supplied by publisher]Related articles

Trends in rates of primary angle closure glaucoma and cataract surgery in England from 1968 to 2004.

Keenan TD, Salmon JF, Yeates D, Goldacre M.

J Glaucoma. 2009 Mar;18(3):201-5.PMID: 19295372 [PubMed - indexed for MEDLINE]Related articles

Protracted developmental trajectories of GABAA receptor alpha1 and alpha2 subunit expression in primate prefrontal cortex.

Hashimoto T, Nguyen QL, Rotaru D, Keenan T, Arion D, Beneyto M, Gonzalez-Burgos G, Lewis DA.

Biol Psychiatry. 2009 Jun 15;65(12):1015-23. Epub 2009 Feb 27.PMID: 19249749 [PubMed - indexed for MEDLINE]Related articles

Factors affecting outcome of punctoplasty surgery: a review of 205 cases.

Shahid H, Sandhu A, Keenan T, Pearson A.

Br J Ophthalmol. 2008 Dec;92(12):1689-92. Epub 2008 Sep 11.PMID: 18786958 [PubMed - indexed for MEDLINE]Related articles

Trends in rates of trabeculectomy in England.

Keenan TD, Salmon JF, Yeates D, Goldacre MJ.

Eye (Lond). 2009 May;23(5):1141-9. Epub 2008 Jul 11.PMID: 18617913 [PubMed - in process]Related articles

SAR of carbon-linked, 2-substituted purines: synthesis and characterization of AP23451 as a novel bone-targeted inhibitor of Src tyrosine kinase with in vivo anti-resorptive activity.

Shakespeare WC, Wang Y, Bohacek R, Keenan T, Sundaramoorthi R, Metcalf C 3rd, Dilauro A, Roeloffzen S, Liu S, Saltmarsh J, Paramanathan G, Dalgarno D, Narula S, Pradeepan S, van Schravendijk MR, Keats J, Ram M, Liou S, Adams S, Wardwell S, Bogus J, Iuliucci J, Weigele M, Xing L, Boyce B, Sawyer TK.

Chem Biol Drug Des. 2008 Feb;71(2):97-105. Epub 2008 Jan 3.PMID: 18179464 [PubMed - indexed for MEDLINE]Related articles

Biomolecular gradients in cell culture systems.

Keenan TM, Folch A.

Lab Chip. 2008 Jan;8(1):34-57. Epub 2007 Dec 6. Review.PMID: 18094760 [PubMed - indexed for MEDLINE]Related articles

Time trends and geographical variation in cataract surgery rates in England: study of surgical workload.

Keenan T, Rosen P, Yeates D, Goldacre M.

Br J Ophthalmol. 2007 Jul;91(7):901-4. Epub 2007 May 31.PMID: 17540694 [PubMed - indexed for MEDLINE]Related articles

Parents with chronic pain: are children equally affected by fathers as mothers in pain? A pilot study.

Evans S, Keenan TR.

J Child Health Care. 2007 Jun;11(2):143-57.PMID: 17494988 [PubMed - indexed for MEDLINE]Related articles

Psychosocial adjustment and physical health of children living with maternal chronic pain.

Evans S, Keenan TR, Shipton EA.

J Paediatr Child Health. 2007 Apr;43(4):262-70.PMID: 17444828 [PubMed - indexed for MEDLINE]Related articles

Measurement of cell migration in response to an evolving radial chemokine gradient triggered by a microvalve.

Frevert CW, Boggy G, Keenan TM, Folch A.

Lab Chip. 2006 Jul;6(7):849-56. Epub 2006 May 12.PMID: 16804588 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyhydroxyalkanoate copolymers from forest biomass.

Keenan TM, Nakas JP, Tanenbaum SW.

J Ind Microbiol Biotechnol. 2006 Jul;33(7):616-26. Epub 2006 Apr 27. Review.PMID: 16761168 [PubMed - indexed for MEDLINE]Related articles

The relationship between maternal chronic pain and child adjustment: the role of parenting as a mediator.

Evans S, Shipton EA, Keenan T.

J Pain. 2006 Apr;7(4):236-43.PMID: 16618467 [PubMed - indexed for MEDLINE]Related articles

Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.

Dalgarno D, Stehle T, Narula S, Schelling P, van Schravendijk MR, Adams S, Andrade L, Keats J, Ram M, Jin L, Grossman T, MacNeil I, Metcalf C 3rd, Shakespeare W, Wang Y, Keenan T, Sundaramoorthi R, Bohacek R, Weigele M, Sawyer T.

Chem Biol Drug Des. 2006 Jan;67(1):46-57.PMID: 16492148 [PubMed - indexed for MEDLINE]Related articles

Psychosocial functioning of mothers with chronic pain: a comparison to pain-free controls.

Evans S, Shipton EA, Keenan TR.

Eur J Pain. 2005 Dec;9(6):683-90.PMID: 16246821 [PubMed - indexed for MEDLINE]Related articles

Automated identification of axonal growth cones in time-lapse image sequences.

Keenan TM, Hooker A, Spilker ME, Li N, Boggy GJ, Vicini P, Folch A.

J Neurosci Methods. 2006 Mar 15;151(2):232-8. Epub 2005 Sep 19.PMID: 16174535 [PubMed - indexed for MEDLINE]Related articles

Bypassing the pump: changing practices in coronary artery surgery.

Keenan TD, Abu-Omar Y, Taggart DP.

Chest. 2005 Jul;128(1):363-9. Review.PMID: 16002958 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular origin and secretion of milk fat globules.

Heid HW, Keenan TW.

Eur J Cell Biol. 2005 Mar;84(2-3):245-58. Review.PMID: 15819405 [PubMed - indexed for MEDLINE]Related articles

Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia.

Barata JT, Keenan TD, Silva A, Nadler LM, Boussiotis VA, Cardoso AA.

Haematologica. 2004 Dec;89(12):1459-67.PMID: 15590396 [PubMed - indexed for MEDLINE]Related articlesFree article

Production and characterization of poly-beta-hydroxyalkanoate copolymers from Burkholderia cepacia utilizing xylose and levulinic acid.

Keenan TM, Tanenbaum SW, Stipanovic AJ, Nakas JP.

Biotechnol Prog. 2004 Nov-Dec;20(6):1697-704.PMID: 15575701 [PubMed - indexed for MEDLINE]Related articles

Novel bone-targeted Src tyrosine kinase inhibitor drug discovery.

Shakespeare WC, Metcalf CA 3rd, Wang Y, Sundaramoorthi R, Keenan T, Weigele M, Bohacek RS, Dalgarno DC, Sawyer TK.

Curr Opin Drug Discov Devel. 2003 Sep;6(5):729-41. Review.PMID: 14579523 [PubMed - indexed for MEDLINE]Related articles

Regulation of gene expression by synthetic dimerizers with novel specificity.

Yang W, Keenan TP, Rozamus LW, Wang X, Rivera VM, Rollins CT, Clackson T, Holt DA.

Bioorg Med Chem Lett. 2003 Oct 6;13(19):3181-4.PMID: 12951089 [PubMed - indexed for MEDLINE]Related articles

Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents.

Vu CB, Luke GP, Kawahata N, Shakespeare WC, Wang Y, Sundaramoorthi R, Metcalf CA 3rd, Keenan TP, Pradeepan S, Corpuz E, Merry T, Bohacek RS, Dalgarno DC, Narula SS, van Schravendijk MR, Ram MK, Adams S, Liou S, Keats JA, Violette SM, Guan W, Weigele M, Sawyer TK.

Bioorg Med Chem Lett. 2003 Sep 15;13(18):3071-4.PMID: 12941336 [PubMed - indexed for MEDLINE]Related articles

Bone-targeted 2,6,9-trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases.

Wang Y, Metcalf CA 3rd, Shakespeare WC, Sundaramoorthi R, Keenan TP, Bohacek RS, van Schravendijk MR, Violette SM, Narula SS, Dalgarno DC, Haraldson C, Keats J, Liou S, Mani U, Pradeepan S, Ram M, Adams S, Weigele M, Sawyer TK.

Bioorg Med Chem Lett. 2003 Sep 15;13(18):3067-70.PMID: 12941335 [PubMed - indexed for MEDLINE]Related articles

Bone-targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues.

Sundaramoorthi R, Shakespeare WC, Keenan TP, Metcalf CA 3rd, Wang Y, Mani U, Taylor M, Liu S, Bohacek RS, Narula SS, Dalgarno DC, van Schravandijk MR, Violette SM, Liou S, Adams S, Ram MK, Keats JA, Weigle M, Sawyer TK, Weigele M.

Bioorg Med Chem Lett. 2003 Sep 15;13(18):3063-6. Erratum in: Bioorg Med Chem Lett. 2003 Dec 15;13(24):4519. PMID: 12941334 [PubMed - indexed for MEDLINE]Related articles

Novel protein kinase inhibitors: SMART drug design technology.

Sawyer TK, Bohacek RS, Metcalf CA 3rd, Shakespeare WC, Wang Y, Sundaramoorthi R, Keenan T, Narula S, Weigele M, Dalgarno DC.

Biotechniques. 2003 Jun;Suppl:2-10, 12-5. Review. No abstract available. PMID: 12813899 [PubMed - indexed for MEDLINE]Related articles

Children's performance on a false-belief task is impaired by activation of an evolutionarily-canalized response system.

Keenan T, Ellis BJ.

J Exp Child Psychol. 2003 Jul;85(3):236-56.PMID: 12810037 [PubMed - indexed for MEDLINE]Related articles

Conflict and conflict resolution: parent and young teen perceptions.

Riesch SK, Gray J, Hoeffs M, Keenan T, Ertl T, Mathison K.

J Pediatr Health Care. 2003 Jan-Feb;17(1):22-31.PMID: 12533729 [PubMed - indexed for MEDLINE]Related articles

Decomposition Analyses Applied to a Complex Ultradian Biorhythm: The Oscillating NADH Oxidase Activity of Plasma Membranes Having a Potential Time-Keeping (Clock) Function.

Foster K, Anwar N, Pogue R, Morré DM, Keenan TW, Morré DJ.

Nonlinearity Biol Toxicol Med. 2003 Jan;1(1):51-70.PMID: 19330112 [PubMed - in process]Related articlesFree article

Entrainment in solution of an oscillating NADH oxidase activity from the bovine milk fat globule membrane with a temperature-compensated period length suggestive of an ultradian time-keeping (clock) function.

Morré DJ, Lawler J, Wang S, Keenan TW, Morré DM.

Biochim Biophys Acta. 2002 Feb 10;1559(1):10-20.PMID: 11825584 [PubMed - indexed for MEDLINE]Related articles

Assembly and secretion of the lipid globules of milk.

Keenan TW.

Adv Exp Med Biol. 2001;501:125-36. Review. No abstract available. PMID: 11787674 [PubMed - indexed for MEDLINE]Related articles

Nonlinear ligament viscoelasticity.

Provenzano P, Lakes R, Keenan T, Vanderby R Jr.

Ann Biomed Eng. 2001 Oct;29(10):908-14.PMID: 11764321 [PubMed - indexed for MEDLINE]Related articles

Milk lipid globules and their surrounding membrane: a brief history and perspectives for future research.

Keenan TW.

J Mammary Gland Biol Neoplasia. 2001 Jul;6(3):365-71. Review.PMID: 11547904 [PubMed - indexed for MEDLINE]Related articles

Nuclear coactivator protein p100 is present in endoplasmic reticulum and lipid droplets of milk secreting cells.

Keenan TW, Winter S, Rackwitz HR, Heid HW.

Biochim Biophys Acta. 2000 Sep 1;1523(1):84-90.PMID: 11099861 [PubMed - indexed for MEDLINE]Related articles

A ligand-reversible dimerization system for controlling protein-protein interactions.

Rollins CT, Rivera VM, Woolfson DN, Keenan T, Hatada M, Adams SE, Andrade LJ, Yaeger D, van Schravendijk MR, Holt DA, Gilman M, Clackson T.

Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7096-101.PMID: 10852943 [PubMed - indexed for MEDLINE]Related articlesFree article

Origin and secretion of milk lipids.

Mather IH, Keenan TW.

J Mammary Gland Biol Neoplasia. 1998 Jul;3(3):259-73. Review.PMID: 10819513 [PubMed - indexed for MEDLINE]Related articles

The cell biology of milk secretion: historical notes. Introduction.

Mather IH, Keenan TW.

J Mammary Gland Biol Neoplasia. 1998 Jul;3(3):227-32. Review. No abstract available. PMID: 10819510 [PubMed - indexed for MEDLINE]Related articles

A theory of mind perspective on cognitive, affective, and intimacy deficits in child sexual offenders.

Keenan T, Ward T.

Sex Abuse. 2000 Jan;12(1):49-60. Review.PMID: 10729959 [PubMed - indexed for MEDLINE]Related articles

Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum.

Rivera VM, Wang X, Wardwell S, Courage NL, Volchuk A, Keenan T, Holt DA, Gilman M, Orci L, Cerasoli F Jr, Rothman JE, Clackson T.

Science. 2000 Feb 4;287(5454):826-30.PMID: 10657290 [PubMed - indexed for MEDLINE]Related articlesFree article

A foundation perspective on Community Access to Child Health Program.

Keenan T.

Pediatrics. 1999 Jun;103(6 Pt 3):1428-9. No abstract available. PMID: 10353967 [PubMed - indexed for MEDLINE]Related articles

Chronic inhalation carcinogenicity study of commercial hexane solvent in F-344 rats and B6C3F1 mice.

Daughtrey W, Newton P, Rhoden R, Kirwin C, Haddock L, Duffy J, Keenan T, Richter W, Nicolich M.

Toxicol Sci. 1999 Mar;48(1):21-9.PMID: 10330680 [PubMed - indexed for MEDLINE]Related articlesFree article

Renin and hemodynamic responses to exercise in borderline hypertensives.

Headley SA, Keenan TG, Manos TM, Phillips K, Lachowetz T, Keenan HA, Mahar MT.

Ethn Dis. 1998 Autumn;8(3):312-8.PMID: 9926901 [PubMed - indexed for MEDLINE]Related articles

Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases.

Heid HW, Moll R, Schwetlick I, Rackwitz HR, Keenan TW.

Cell Tissue Res. 1998 Nov;294(2):309-21.PMID: 9799447 [PubMed - indexed for MEDLINE]Related articles

Synthesis and activity of bivalent FKBP12 ligands for the regulated dimerization of proteins.

Keenan T, Yaeger DR, Courage NL, Rollins CT, Pavone ME, Rivera VM, Yang W, Guo T, Amara JF, Clackson T, Gilman M, Holt DA.

Bioorg Med Chem. 1998 Aug;6(8):1309-35.PMID: 9784872 [PubMed - indexed for MEDLINE]Related articles

Biochemistry of the Golgi apparatus.

Keenan TW.

Histochem Cell Biol. 1998 May-Jun;109(5-6):505-16. Review. No abstract available. PMID: 9681631 [PubMed - indexed for MEDLINE]Related articles

A versatile synthetic dimerizer for the regulation of protein-protein interactions.

Amara JF, Clackson T, Rivera VM, Guo T, Keenan T, Natesan S, Pollock R, Yang W, Courage NL, Holt DA, Gilman M.

Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10618-23.PMID: 9380684 [PubMed - indexed for MEDLINE]Related articlesFree article

Care of patients with type II diabetes: a study of family physicians' compliance with clinical practice guidelines.

Worrall G, Freake D, Kelland J, Pickle A, Keenan T.

J Fam Pract. 1997 Apr;44(4):374-81.PMID: 9108835 [PubMed - indexed for MEDLINE]Related articles

Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane.

Heid HW, Schnölzer M, Keenan TW.

Biochem J. 1996 Dec 15;320 ( Pt 3):1025-30.PMID: 9003395 [PubMed - indexed for MEDLINE]Related articlesFree article

A humanized system for pharmacologic control of gene expression.

Rivera VM, Clackson T, Natesan S, Pollock R, Amara JF, Keenan T, Magari SR, Phillips T, Courage NL, Cerasoli F Jr, Holt DA, Gilman M.

Nat Med. 1996 Sep;2(9):1028-32.PMID: 8782462 [PubMed - indexed for MEDLINE]Related articles

Design and synthesis of nonpeptide peptidomimetic inhibitors of renin.

Smith AB 3rd, Akaishi R, Jones DR, Keenan TP, Guzman MC, Holcomb RC, Sprengeler PA, Wood JL, Hirschmann R, Holloway MK.

Biopolymers. 1995;37(1):29-53.PMID: 7880965 [PubMed - indexed for MEDLINE]Related articles