PubMed

Bioinformatic Analysis of Gene Sets Regulated by Ligand-Activated and Dominant-Negative Peroxisome Proliferator-Activated Receptor {gamma} in Mouse Aorta.

Keen HL, Halabi CM, Beyer AM, de Lange WJ, Liu X, Maeda N, Faraci FM, Casavant TL, Sigmund CD.

Arterioscler Thromb Vasc Biol. 2009 Dec 17. [Epub ahead of print]PMID: 20018933 [PubMed - as supplied by publisher]

Usefulness of ultrasound in osteoarthritis.

Keen HI, Conaghan PG.

Rheum Dis Clin North Am. 2009 Aug;35(3):503-19.PMID: 19931801 [PubMed - in process]Related articles

Assessing single joints in arthritis clinical trials.

Keen HI, Bingham CO 3rd, Bradley LA, Conaghan PG, Heald AE, Kaeley GS, Maksymowych WP, Moskowitz RW, Schumacher HR Jr, Woodworth TE, Mease PJ.

J Rheumatol. 2009 Sep;36(9):2092-6. Review.PMID: 19738219 [PubMed - indexed for MEDLINE]Related articles

The OMERACT ultrasound task force -- Advances and priorities.

D'Agostino MA, Conaghan PG, Naredo E, Aegerter P, Iagnocco A, Freeston JE, Filippucci E, Moller I, Pineda C, Joshua F, Backhaus M, Keen HI, Kaeley G, Zisweiler HR, Schmidt WA, Balint PV, Bruyn GA, Jousse-Joulin S, Kane D, Moller I, Szkudlarek M, Terslev L, Wakefield RJ.

J Rheumatol. 2009 Aug;36(8):1829-32.PMID: 19671821 [PubMed - indexed for MEDLINE]Related articles

L-type voltage-dependent calcium channel antagonists impair perirhinal long-term recognition memory and plasticity processes.

Seoane A, Massey PV, Keen H, Bashir ZI, Brown MW.

J Neurosci. 2009 Jul 29;29(30):9534-44.PMID: 19641116 [PubMed - indexed for MEDLINE]Related articles

Ultrasonography in osteoarthritis.

Keen HI, Conaghan PG.

Radiol Clin North Am. 2009 Jul;47(4):581-94. Review.PMID: 19631070 [PubMed - indexed for MEDLINE]Related articles

Disease remission state in patients treated with the combination of tumor necrosis factor blockade and methotrexate or with disease-modifying antirheumatic drugs: A clinical and imaging comparative study.

Saleem B, Brown AK, Keen H, Nizam S, Freeston J, Karim Z, Quinn M, Wakefield R, Hensor E, Conaghan PG, Emery P.

Arthritis Rheum. 2009 Jul;60(7):1915-22.PMID: 19565512 [PubMed - indexed for MEDLINE]Related articles

Regulation of renin gene expression by oxidative stress.

Itani H, Liu X, Sarsour EH, Goswami PC, Born E, Keen HL, Sigmund CD.

Hypertension. 2009 Jun;53(6):1070-6. Epub 2009 May 11.PMID: 19433777 [PubMed - indexed for MEDLINE]Related articles

A systematic review of ultrasonography in osteoarthritis.

Keen HI, Wakefield RJ, Conaghan PG.

Ann Rheum Dis. 2009 May;68(5):611-9. Review.PMID: 19366893 [PubMed - indexed for MEDLINE]Related articles

Clinical and imaging efficacy of infliximab in HLA-B27-Positive patients with magnetic resonance imaging-determined early sacroiliitis.

Barkham N, Keen HI, Coates LC, O'Connor P, Hensor E, Fraser AD, Cawkwell LS, Bennett A, McGonagle D, Emery P.

Arthritis Rheum. 2009 Apr;60(4):946-54.PMID: 19333933 [PubMed - indexed for MEDLINE]Related articles

Osteoarthritis: current role of imaging.

Guermazi A, Eckstein F, Hellio Le Graverand-Gastineau MP, Conaghan PG, Burstein D, Keen H, Roemer FW.

Med Clin North Am. 2009 Jan;93(1):101-26, xi.PMID: 19059024 [PubMed - indexed for MEDLINE]Related articles

An ultrasonographic study of osteoarthritis of the hand: synovitis and its relationship to structural pathology and symptoms.

Keen HI, Wakefield RJ, Grainger AJ, Hensor EM, Emery P, Conaghan PG.

Arthritis Rheum. 2008 Dec 15;59(12):1756-63.PMID: 19035429 [PubMed - indexed for MEDLINE]Related articlesFree article

Imaging in osteoarthritis.

Guermazi A, Burstein D, Conaghan P, Eckstein F, Hellio Le Graverand-Gastineau MP, Keen H, Roemer FW.

Rheum Dis Clin North Am. 2008 Aug;34(3):645-87. Review.PMID: 18687277 [PubMed - indexed for MEDLINE]Related articles

Endothelium-specific interference with peroxisome proliferator activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet.

Beyer AM, de Lange WJ, Halabi CM, Modrick ML, Keen HL, Faraci FM, Sigmund CD.

Circ Res. 2008 Sep 12;103(6):654-61. Epub 2008 Jul 31.PMID: 18676352 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysregulated human renin expression in transgenic mice carrying truncated genomic constructs: evidence supporting the presence of insulators at the renin locus.

Zhou X, Weatherford ET, Liu X, Born E, Keen HL, Sigmund CD.

Am J Physiol Renal Physiol. 2008 Sep;295(3):F642-53. Epub 2008 Jul 16.PMID: 18632798 [PubMed - indexed for MEDLINE]Related articlesFree article

Mild autonomic dysfunction in primary Sjögren's syndrome: a controlled study.

Cai FZ, Lester S, Lu T, Keen H, Boundy K, Proudman SM, Tonkin A, Rischmueller M.

Arthritis Res Ther. 2008;10(2):R31. Epub 2008 Mar 7.PMID: 18328102 [PubMed - indexed for MEDLINE]Related articlesFree article

Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension.

Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD.

Cell Metab. 2008 Mar;7(3):215-26.PMID: 18316027 [PubMed - indexed for MEDLINE]Related articlesFree article

Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling.

Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM.

Hypertension. 2008 Apr;51(4):867-71. Epub 2008 Feb 19. Erratum in: Hypertension. 2008 Apr;51(4):e33. PMID: 18285614 [PubMed - indexed for MEDLINE]Related articlesFree article

Can ultrasonography improve on radiographic assessment in osteoarthritis of the hands? A comparison between radiographic and ultrasonographic detected pathology.

Keen HI, Wakefield RJ, Grainger AJ, Hensor EM, Emery P, Conaghan PG.

Ann Rheum Dis. 2008 Aug;67(8):1116-20. Epub 2007 Nov 23.PMID: 18037626 [PubMed - indexed for MEDLINE]Related articles

Imaging inflamed synovial joints.

Tan AL, Keen HI, Emery P, McGonagle D.

Methods Mol Med. 2007;135:3-26. Review.PMID: 17951649 [PubMed - indexed for MEDLINE]Related articles

Is peroxisome proliferator-activated receptor-gamma a new "pal" of renin?

Weatherford ET, Itani H, Keen HL, Sigmund CD.

Hypertension. 2007 Nov;50(5):844-6. Epub 2007 Sep 4. No abstract available. PMID: 17785627 [PubMed - indexed for MEDLINE]Related articlesFree article

The development of a preliminary ultrasonographic scoring system for features of hand osteoarthritis.

Keen HI, Lavie F, Wakefield RJ, D'Agostino MA, Hammer HB, Hensor E, Pendleton A, Kane D, Guerini H, Schueller-Weidekamm C, Kortekaas MC, Birrel F, Kloppenburg M, Stamm T, Watt I, Smolen JS, Maheu E, Dougados M, Conaghan PG.

Ann Rheum Dis. 2008 May;67(5):651-5. Epub 2007 Aug 17. Review.PMID: 17704062 [PubMed - indexed for MEDLINE]Related articles

A diabetic life before and after the insulin era.

Brostoff JM, Keen H, Brostoff J.

Diabetologia. 2007 Jun;50(6):1351-3. Epub 2007 Apr 11. No abstract available. PMID: 17429604 [PubMed - indexed for MEDLINE]Related articles

Response-driven combination therapy with conventional disease-modifying antirheumatic drugs can achieve high response rates in early rheumatoid arthritis with minimal glucocorticoid and nonsteroidal anti-inflammatory drug use.

Proudman SM, Keen HI, Stamp LK, Lee AT, Goldblatt F, Ayres OC, Rischmueller M, James MJ, Hill CL, Caughey GE, Cleland LG.

Semin Arthritis Rheum. 2007 Oct;37(2):99-111. Epub 2007 Mar 27.PMID: 17391739 [PubMed - indexed for MEDLINE]Related articles

First exons and introns--a survey of GC content and gene structure in the human genome.

Kalari KR, Casavant M, Bair TB, Keen HL, Comeron JM, Casavant TL, Scheetz TE.

In Silico Biol. 2006;6(3):237-42.PMID: 16922687 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-tumour necrosis factor-alpha therapy over conventional therapy improves endothelial function in adults with rheumatoid arthritis.

Bilsborough W, Keen H, Taylor A, O'Driscoll GJ, Arnolda L, Green DJ.

Rheumatol Int. 2006 Oct;26(12):1125-31. Epub 2006 Jun 24.PMID: 16799778 [PubMed - indexed for MEDLINE]Related articles

Diabetes and the quality and outcomes framework: diabetes needs reintegration of primary and secondary care.

Keen H.

BMJ. 2005 Dec 3;331(7528):1340. No abstract available. PMID: 16322040 [PubMed - indexed for MEDLINE]Related articlesFree article

MRI and musculoskeletal ultrasonography as diagnostic tools in early arthritis.

Keen HI, Brown AK, Wakefield RJ, Conaghan PG.

Rheum Dis Clin North Am. 2005 Nov;31(4):699-714. Review.PMID: 16287592 [PubMed - indexed for MEDLINE]Related articles

The prevalence of underpowered randomized clinical trials in rheumatology.

Keen HI, Pile K, Hill CL.

J Rheumatol. 2005 Nov;32(11):2083-8.PMID: 16265683 [PubMed - indexed for MEDLINE]Related articles

Prix Maurice Dérot 2005. Clinical epidemiology and diabetes research.

Keen H.

Journ Annu Diabetol Hotel Dieu. 2005:177-82. No abstract available. PMID: 16161318 [PubMed - indexed for MEDLINE]Related articles

Cancer incidence and mortality in patients with insulin-treated diabetes: a UK cohort study.

Swerdlow AJ, Laing SP, Qiao Z, Slater SD, Burden AC, Botha JL, Waugh NR, Morris AD, Gatling W, Gale EA, Patterson CC, Keen H.

Br J Cancer. 2005 Jun 6;92(11):2070-5.PMID: 15886700 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional comparison of annexin V analogues labeled indirectly and directly with iodine-124.

Dekker B, Keen H, Shaw D, Disley L, Hastings D, Hadfield J, Reader A, Allan D, Julyan P, Watson A, Zweit J.

Nucl Med Biol. 2005 May;32(4):403-13.PMID: 15878510 [PubMed - indexed for MEDLINE]Related articles

Imaging apoptosis in vivo using 124I-annexin V and PET.

Keen HG, Dekker BA, Disley L, Hastings D, Lyons S, Reader AJ, Ottewell P, Watson A, Zweit J.

Nucl Med Biol. 2005 May;32(4):395-402.PMID: 15878509 [PubMed - indexed for MEDLINE]Related articles

How should we manage early rheumatoid arthritis? From imaging to intervention.

Keen HI, Emery P.

Curr Opin Rheumatol. 2005 May;17(3):280-5. Review.PMID: 15838237 [PubMed - indexed for MEDLINE]Related articles

MBP-annexin V radiolabeled directly with iodine-124 can be used to image apoptosis in vivo using PET.

Dekker B, Keen H, Lyons S, Disley L, Hastings D, Reader A, Ottewell P, Watson A, Zweit J.

Nucl Med Biol. 2005 Apr;32(3):241-52.PMID: 15820759 [PubMed - indexed for MEDLINE]Related articles

Transgenic mice for studies of the renin-angiotensin system in hypertension.

Lavoie JL, Bianco RA, Sakai K, Keen HL, Ryan MJ, Sigmund CD.

Acta Physiol Scand. 2004 Aug;181(4):571-7. Review.PMID: 15283772 [PubMed - indexed for MEDLINE]Related articles

Mortality of South Asian patients with insulin-treated diabetes mellitus in the United Kingdom: a cohort study.

Swerdlow AJ, Laing SP, Dos Santos Silva I, Slater SD, Burden AC, Botha JL, Waugh NR, Morris AD, Gatling W, Bingley PJ, Patterson CC, Qiao Z, Keen H.

Diabet Med. 2004 Aug;21(8):845-51.PMID: 15270787 [PubMed - indexed for MEDLINE]Related articles

Gene expression profiling of potential PPARgamma target genes in mouse aorta.

Keen HL, Ryan MJ, Beyer A, Mathur S, Scheetz TE, Gackle BD, Faraci FM, Casavant TL, Sigmund CD.

Physiol Genomics. 2004 Jun 17;18(1):33-42.PMID: 15054141 [PubMed - indexed for MEDLINE]Related articlesFree article

Untraditional methods for targeting the kidney in transgenic mice.

Bianco RA, Keen HL, Lavoie JL, Sigmund CD.

Am J Physiol Renal Physiol. 2003 Dec;285(6):F1027-33. Review.PMID: 14600026 [PubMed - indexed for MEDLINE]Related articlesFree article

Mortality from cerebrovascular disease in a cohort of 23 000 patients with insulin-treated diabetes.

Laing SP, Swerdlow AJ, Carpenter LM, Slater SD, Burden AC, Botha JL, Morris AD, Waugh NR, Gatling W, Gale EA, Patterson CC, Qiao Z, Keen H.

Stroke. 2003 Feb;34(2):418-21.PMID: 12574553 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiological significance of two common haplotypes of human angiotensinogen using gene targeting in the mouse.

Cvetkovic B, Keen HL, Zhang X, Davis D, Yang B, Sigmund CD.

Physiol Genomics. 2002 Dec 3;11(3):253-62.PMID: 12388794 [PubMed - indexed for MEDLINE]Related articlesFree article

On your feet! Workshop on the diabetic foot.

Assal JP, Mehnert H, Tritschler HJ, Sidorenko A, Keen H; Hellmut Mehnert Award Workshop Participants.

J Diabetes Complications. 2002 Mar-Apr;16(2):183-94. No abstract available. PMID: 12039404 [PubMed - indexed for MEDLINE]Related articles

Lower blood pressure in floxed angiotensinogen mice after adenoviral delivery of Cre-recombinase.

Stec DE, Keen HL, Sigmund CD.

Hypertension. 2002 Feb;39(2 Pt 2):629-33.PMID: 11882621 [PubMed - indexed for MEDLINE]Related articlesFree article

Continuous subcutaneous insulin infusion at 25 years: evidence base for the expanding use of insulin pump therapy in type 1 diabetes.

Pickup J, Keen H.

Diabetes Care. 2002 Mar;25(3):593-8. Review.PMID: 11874953 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular disease prevalence in diabetic patients in China: standardised comparison with the 14 centres in the WHO Multinational Study of Vascular Disease in Diabetes.

Chi ZS, Lee ET, Lu M, Keen H, Bennett PH.

Diabetologia. 2001 Sep;44 Suppl 2:S82-6.PMID: 11587055 [PubMed - indexed for MEDLINE]Related articles

Vascular disease in younger-onset diabetes: comparison of European, Asian and American Indian cohorts of the WHO Multinational Study of Vascular Disease in Diabetes.

Lee ET, Lu M, Bennett PH, Keen H.

Diabetologia. 2001 Sep;44 Suppl 2:S78-81.PMID: 11587054 [PubMed - indexed for MEDLINE]Related articles

An analysis of serial Minnesota ECG code changes in the London cohort of the WHO Multinational Study of Vascular Disease in Diabetes.

Keen H, Morrish N, Lee ET.

Diabetologia. 2001 Sep;44 Suppl 2:S72-7.PMID: 11587053 [PubMed - indexed for MEDLINE]Related articles

Risk factors for renal failure: the WHO Mulinational Study of Vascular Disease in Diabetes.

Colhoun HM, Lee ET, Bennett PH, Lu M, Keen H, Wang SL, Stevens LK, Fuller JH.

Diabetologia. 2001 Sep;44 Suppl 2:S46-53.PMID: 11587050 [PubMed - indexed for MEDLINE]Related articles

Increased urinary albumin excretion and its associations in the WHO Multinational Study of Vascular Disease in Diabetes.

Bennett PH, Lee ET, Lu M, Keen H, Fuller JH.

Diabetologia. 2001 Sep;44 Suppl 2:S37-45.PMID: 11587049 [PubMed - indexed for MEDLINE]Related articles

The incidence of visual impairment and its determinants in the WHO Multinational Study of Vascular Disease in Diabetes.

Miki E, Lu M, Lee ET, Keen H, Bennett PH, Russell D.

Diabetologia. 2001 Sep;44 Suppl 2:S31-6.PMID: 11587048 [PubMed - indexed for MEDLINE]Related articles