PubMed

Familial and phenotypic associations of the aldosterone Renin ratio.

Alvarez-Madrazo S, Padmanabhan S, Mayosi BM, Watkins H, Avery P, Wallace AM, Fraser R, Davies E, Keavney B, Connell JM.

J Clin Endocrinol Metab. 2009 Nov;94(11):4324-33. Epub 2009 Oct 9.PMID: 19820005 [PubMed - in process]Related articles

Genetic variation in VEGF does not contribute significantly to the risk of congenital cardiovascular malformation.

Griffin HR, Hall DH, Topf A, Eden J, Stuart AG, Parsons J, Peart I, Deanfield JE, O'Sullivan J, Babu-Narayan SV, Gatzoulis MA, Bu'lock FA, Bhattacharya S, Bentham J, Farrall M, Riveron JG, Brook JD, Burn J, Cordell HJ, Goodship JA, Keavney B.

PLoS One. 2009;4(3):e4978. Epub 2009 Mar 24.PMID: 19308252 [PubMed - indexed for MEDLINE]Related articlesFree article

Fresh fields and pathways new: recent genetic insights into cardiac malformation.

Leong FT, Freeman LJ, Keavney BD.

Heart. 2009 Mar;95(6):442-7. Review.PMID: 19252006 [PubMed - indexed for MEDLINE]Related articles

Local vessel injury following percutaneous coronary intervention does not promote early mobilisation of endothelial progenitor cells in the absence of myocardial necrosis.

Thomas HE, Avery PJ, Ahmed JM, Edwards R, Purcell I, Zaman AG, Arthur HM, Keavney BD.

Heart. 2009 Apr;95(7):555-8. Epub 2008 Oct 31.PMID: 18977801 [PubMed - indexed for MEDLINE]Related articles

Ambulatory blood pressure is associated with polymorphic variation in P2X receptor genes.

Palomino-Doza J, Rahman TJ, Avery PJ, Mayosi BM, Farrall M, Watkins H, Edwards CR, Keavney B.

Hypertension. 2008 Nov;52(5):980-5. Epub 2008 Oct 13.PMID: 18852390 [PubMed - indexed for MEDLINE]Related articlesFree article

More evidence against a causal association between C-reactive protein and diabetes.

Keavney B.

PLoS Med. 2008 Aug 12;5(8):e174. No abstract available. PMID: 18700815 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes.

Cunnington MS, Mayosi BM, Hall DH, Avery PJ, Farrall M, Vickers MA, Watkins H, Keavney B.

Atherosclerosis. 2009 Mar;203(1):41-4. Epub 2008 Jul 3.PMID: 18675980 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating endothelial progenitor cell numbers are not associated with donor organ age or allograft vasculopathy in cardiac transplant recipients.

Thomas HE, Parry G, Dark JH, Arthur HM, Keavney BD.

Atherosclerosis. 2009 Feb;202(2):612-6. Epub 2008 May 20.PMID: 18589426 [PubMed - indexed for MEDLINE]Related articles

Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk.

Thompson A, Di Angelantonio E, Sarwar N, Erqou S, Saleheen D, Dullaart RP, Keavney B, Ye Z, Danesh J.

JAMA. 2008 Jun 18;299(23):2777-88. Review.PMID: 18560005 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating endothelial progenitor cells exhibit diurnal variation.

Thomas HE, Redgrave R, Cunnington MS, Avery P, Keavney BD, Arthur HM.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):e21-2. No abstract available. PMID: 18296584 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide linkage analysis of electrocardiographic and echocardiographic left ventricular hypertrophy in families with hypertension.

Mayosi BM, Avery PJ, Farrall M, Keavney B, Watkins H.

Eur Heart J. 2008 Feb;29(4):525-30.PMID: 18276622 [PubMed - indexed for MEDLINE]Related articlesFree article

Correction of population stratification in large multi-ethnic association studies.

Serre D, Montpetit A, Paré G, Engert JC, Yusuf S, Keavney B, Hudson TJ, Anand S.

PLoS One. 2008 Jan 2;3(1):e1382.PMID: 18196181 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma potassium level is associated with common genetic variation in the beta-subunit of the epithelial sodium channel.

Gaukrodger N, Avery PJ, Keavney B.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R1068-72. Epub 2008 Jan 9.PMID: 18184758 [PubMed - indexed for MEDLINE]Related articles

Common genetic variation in the type A endothelin-1 receptor is associated with ambulatory blood pressure: a family study.

Rahman T, Baker M, Hall DH, Avery PJ, Keavney B.

J Hum Hypertens. 2008 Apr;22(4):282-8. Epub 2008 Jan 3.PMID: 18172451 [PubMed - indexed for MEDLINE]Related articles

The C-532T polymorphism of the angiotensinogen gene is associated with pulse pressure: a possible explanation for heterogeneity in genetic association studies of AGT and hypertension.

Baker M, Rahman T, Hall D, Avery PJ, Mayosi BM, Connell JM, Farrall M, Watkins H, Keavney B.

Int J Epidemiol. 2007 Dec;36(6):1356-62. Epub 2007 Nov 12.PMID: 17998241 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of apolipoprotein E genotypes with lipid levels and coronary risk.

Bennet AM, Di Angelantonio E, Ye Z, Wensley F, Dahlin A, Ahlbom A, Keavney B, Collins R, Wiman B, de Faire U, Danesh J.

JAMA. 2007 Sep 19;298(11):1300-11. Review.PMID: 17878422 [PubMed - indexed for MEDLINE]Related articlesFree article

Telomere length is associated with left ventricular function in the oldest old: the Newcastle 85+ study.

Collerton J, Martin-Ruiz C, Kenny A, Barrass K, von Zglinicki T, Kirkwood T, Keavney B; Newcastle 85+ Core Study Team.

Eur Heart J. 2007 Jan;28(2):172-6. Epub 2007 Jan 10.PMID: 17215319 [PubMed - indexed for MEDLINE]Related articlesFree article

INSIG-2 promoter polymorphism and obesity related phenotypes: association study in 1428 members of 248 families.

Hall DH, Rahman T, Avery PJ, Keavney B.

BMC Med Genet. 2006 Nov 30;7:83.PMID: 17137505 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll the bell for another genetic association?

Keavney B.

Eur Heart J. 2006 Nov;27(21):2489-90. Epub 2006 Oct 6. No abstract available. PMID: 17028110 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

Imrie H, Freel M, Mayosi BM, Davies E, Fraser R, Ingram M, Cordell HJ, Farrall M, Avery PJ, Watkins H, Keavney B, Connell JM.

J Clin Endocrinol Metab. 2006 Dec;91(12):5051-6. Epub 2006 Sep 19.PMID: 16984984 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'.

Keavney B, Danesh J, Parish S, Palmer A, Clark S, Youngman L, Delépine M, Lathrop M, Peto R, Collins R.

Int J Epidemiol. 2006 Aug;35(4):935-43. Epub 2006 Jul 26.PMID: 16870675 [PubMed - indexed for MEDLINE]Related articlesFree article

Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.

Ye Z, Liu EH, Higgins JP, Keavney BD, Lowe GD, Collins R, Danesh J.

Lancet. 2006 Feb 25;367(9511):651-8. Review.PMID: 16503463 [PubMed - indexed for MEDLINE]Related articles

Common genetic polymorphisms and coronary heart disease.

Keavney B.

Semin Vasc Med. 2002 Aug;2(3):233-41. Review.PMID: 16222616 [PubMed - indexed for MEDLINE]Related articles

Genotype at the -174G/C polymorphism of the interleukin-6 gene is associated with common carotid artery intimal-medial thickness: family study and meta-analysis.

Mayosi BM, Avery PJ, Baker M, Gaukrodger N, Imrie H, Green FR, Farrall M, Watkins H, Keavney B.

Stroke. 2005 Oct;36(10):2215-9. Epub 2005 Sep 22.PMID: 16179573 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between common polymorphisms of the proopiomelanocortin gene and body fat distribution: a family study.

Baker M, Gaukrodger N, Mayosi BM, Imrie H, Farrall M, Watkins H, Connell JM, Avery PJ, Keavney B.

Diabetes. 2005 Aug;54(8):2492-6.PMID: 16046320 [PubMed - indexed for MEDLINE]Related articlesFree article

A rare variant of the leptin gene has large effects on blood pressure and carotid intima-medial thickness: a study of 1428 individuals in 248 families.

Gaukrodger N, Mayosi BM, Imrie H, Avery P, Baker M, Connell JM, Watkins H, Farrall M, Keavney B.

J Med Genet. 2005 Jun;42(6):474-8.PMID: 15937081 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.

Keavney B, Mayosi B, Gaukrodger N, Imrie H, Baker M, Fraser R, Ingram M, Watkins H, Farrall M, Davies E, Connell J.

J Clin Endocrinol Metab. 2005 Feb;90(2):1072-7. Epub 2004 Nov 2.PMID: 15522937 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk.

Keavney B, Palmer A, Parish S, Clark S, Youngman L, Danesh J, McKenzie C, Delépine M, Lathrop M, Peto R, Collins R; International Studies of Infarct Survival (ISIS) Collaborators.

Int J Epidemiol. 2004 Oct;33(5):1002-13. Epub 2004 Jul 15.PMID: 15256516 [PubMed - indexed for MEDLINE]Related articlesFree article

Commentary: Katan's remarkable foresight: genes and causality 18 years on.

Keavney B.

Int J Epidemiol. 2004 Feb;33(1):11-4. No abstract available. PMID: 15075138 [PubMed - indexed for MEDLINE]Related articlesFree article

Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies.

Wheeler JG, Keavney BD, Watkins H, Collins R, Danesh J.

Lancet. 2004 Feb 28;363(9410):689-95.PMID: 15001326 [PubMed - indexed for MEDLINE]Related articles

Measured haplotype analysis of the aldosterone synthase gene and heart size.

Mayosi BM, Keavney B, Watkins H, Farrall M.

Eur J Hum Genet. 2003 May;11(5):395-401. Erratum in: Eur J Hum Genet. 2005 Aug;13(8):992. PMID: 12734545 [PubMed - indexed for MEDLINE]Related articlesFree article

Outcome following percutaneous coronary intervention: not, so far, in our genes.

Keavney B.

Heart. 2003 Mar;89(3):247-8. No abstract available. PMID: 12591817 [PubMed - indexed for MEDLINE]Related articlesFree article

Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E epsilon2/epsilon3/epsilon4 genotype.

Keavney B, Parish S, Palmer A, Clark S, Youngman L, Danesh J, McKenzie C, Delépine M, Lathrop M, Peto R, Collins R; International Studies of Infarct Survival (ISIS) Collaborators.

Lancet. 2003 Feb 1;361(9355):396-8.PMID: 12573381 [PubMed - indexed for MEDLINE]Related articles

Electrocardiographic measures of left ventricular hypertrophy show greater heritability than echocardiographic left ventricular mass.

Mayosi BM, Keavney B, Kardos A, Davies CH, Ratcliffe PJ, Farrall M, Watkins H.

Eur Heart J. 2002 Dec;23(24):1963-71.PMID: 12473259 [PubMed - indexed for MEDLINE]Related articles

Angiotensin converting enzyme insertion or deletion polymorphism and coronary restenosis: meta-analysis of 16 studies.

Bonnici F, Keavney B, Collins R, Danesh J.

BMJ. 2002 Sep 7;325(7363):517-20.PMID: 12217990 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic epidemiological studies of coronary heart disease.

Keavney B.

Int J Epidemiol. 2002 Aug;31(4):730-6. Review. No abstract available. PMID: 12177010 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein.

Vickers MA, Green FR, Terry C, Mayosi BM, Julier C, Lathrop M, Ratcliffe PJ, Watkins HC, Keavney B.

Cardiovasc Res. 2002 Mar;53(4):1029-34.PMID: 11922913 [PubMed - indexed for MEDLINE]Related articlesFree article

SNPs and snails and puppy dogs' tails: analysis of SNP haplotype data using the gamete competition model.

Sinsheimer JS, McKenzie CA, Keavney B, Lange K.

Ann Hum Genet. 2001 Sep;65(Pt 5):483-90.PMID: 11806856 [PubMed - indexed for MEDLINE]Related articles

Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE).

McKenzie CA, Abecasis GR, Keavney B, Forrester T, Ratcliffe PJ, Julier C, Connell JM, Bennett F, McFarlane-Anderson N, Lathrop GM, Cardon LR.

Hum Mol Genet. 2001 May 1;10(10):1077-84.PMID: 11331618 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolution of genetic analysis strategies in coronary heart disease: a case of unnatural selection?

Keavney B, Watkins H.

Eur Heart J. 2001 Feb;22(4):271-3. No abstract available. PMID: 11161941 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics of coronary heart disease: current knowledge and research principles.

Winkelmann BR, Hager J, Kraus WE, Merlini P, Keavney B, Grant PJ, Muhlestein JB, Granger CB.

Am Heart J. 2000 Oct;140(4):S11-26. Review. No abstract available. PMID: 11011311 [PubMed - indexed for MEDLINE]Related articles

Recommendations for national and local regulatory authorities concerning research in genetic markers of disease.

Granger CB, Keavney B, Francomano C, Olsson G, Yusuf S.

Am Heart J. 2000 Oct;140(4):S3-5. Review. No abstract available. PMID: 11011309 [PubMed - indexed for MEDLINE]Related articles

Measurement of blood pressure using the auscultatory and oscillometric methods in the same cuff deflation: validation and field trial of the A&D TM2421 monitor.

Keavney B, Bird R, Caiazza A, Casadei B, Conway J.

J Hum Hypertens. 2000 Sep;14(9):573-9.PMID: 10980589 [PubMed - indexed for MEDLINE]Related articles

Genetic association studies in complex diseases.

Keavney B.

J Hum Hypertens. 2000 Jun;14(6):361-7. Review.PMID: 10878695 [PubMed - indexed for MEDLINE]Related articles

Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators.

Keavney B, McKenzie C, Parish S, Palmer A, Clark S, Youngman L, Delépine M, Lathrop M, Peto R, Collins R.

Lancet. 2000 Feb 5;355(9202):434-42.PMID: 10841123 [PubMed - indexed for MEDLINE]Related articles

Screening for the GRA mutation in Jamaica.

McKenzie CA, Keavney B, Forrester T, Julier C, Ratcliffe PJ.

J Hum Hypertens. 2000 Feb;14(2):157-8. No abstract available. PMID: 10723126 [PubMed - indexed for MEDLINE]Related articles

Fine-mapping of an ancestral recombination breakpoint in DCP1.

Farrall M, Keavney B, McKenzie C, Delépine M, Matsuda F, Lathrop GM.

Nat Genet. 1999 Nov;23(3):270-1. No abstract available. PMID: 10545941 [PubMed - indexed for MEDLINE]Related articles

Measured haplotype analysis of the angiotensin-I converting enzyme gene.

Keavney B, McKenzie CA, Connell JM, Julier C, Ratcliffe PJ, Sobel E, Lathrop M, Farrall M.

Hum Mol Genet. 1998 Oct;7(11):1745-51.PMID: 9736776 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of the angiotensinogen locus in human essential hypertension: a European study.

Brand E, Chatelain N, Keavney B, Caulfield M, Citterio L, Connell J, Grobbee D, Schmidt S, Schunkert H, Schuster H, Sharma AM, Soubrier F.

Hypertension. 1998 Mar;31(3):725-9.PMID: 9495253 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10.

Julier C, Delépine M, Keavney B, Terwilliger J, Davis S, Weeks DE, Bui T, Jeunemaître X, Velho G, Froguel P, Ratcliffe P, Corvol P, Soubrier F, Lathrop GM.

Hum Mol Genet. 1997 Nov;6(12):2077-85.PMID: 9328471 [PubMed - indexed for MEDLINE]Related articlesFree article