PubMed

Taking a Unified Approach to Teaching and Implementing Quality Improvements Across Multiple Residency Programs: The Atlantic Health Experience.

Daniel DM, Casey DE Jr, Levine JL, Kaye ST, Dardik RB, Varkey P, Pierce-Boggs K.

Acad Med. 2009 Dec;84(12):1788-1795.PMID: 19940589 [PubMed - as supplied by publisher]

Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia, West Africa.

Mendy ME, Welzel T, Lesi OA, Hainaut P, Hall AJ, Kuniholm MH, McConkey S, Goedert JJ, Kaye S, Rowland-Jones S, Whittle H, Kirk GD.

J Viral Hepat. 2009 Oct 27. [Epub ahead of print]PMID: 19874478 [PubMed - as supplied by publisher]Related articles

Biomarker-Driven Early Clinical Trials in Oncology: A Paradigm Shift in Drug Development.

Tan DS, Thomas GV, Garrett MD, Banerji U, de Bono JS, Kaye SB, Workman P.

Cancer J. 2009 September/October;15(5):406-420.PMID: 19826361 [PubMed - as supplied by publisher]Related articles

Long-term Topical Steroid Treatment after Penetrating Keratoplasty in Patients with Pseudophakic Bullous Keratopathy.

Ross AH, Jones MN, Nguyen DQ, Jaycock PD, Armitage WJ, Cook SD, Kaye SB, Tole DM; National Health Service Blood and Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists.

Ophthalmology. 2009 Oct 6. [Epub ahead of print]PMID: 19815284 [PubMed - as supplied by publisher]Related articles

Capsular distention syndrome: sine anterior chamber shallowing?

Karri B, Sebastian RT, Kaye SB.

Can J Ophthalmol. 2009 Oct;44(5):e45. No abstract available. PMID: 19798816 [PubMed - indexed for MEDLINE]Related articles

The role of human endogenous retroviruses in melanoma.

Singh S, Kaye S, Gore ME, McClure MO, Bunker CB.

Br J Dermatol. 2009 Jul 20. [Epub ahead of print]PMID: 19785608 [PubMed - as supplied by publisher]Related articles

Bacterial susceptibility to topical antimicrobials and clinical outcome in bacterial keratitis.

Kaye SB, Tuft S, Neal T, Tole D, Leeming J, Figueiredo F, Armstrong M, McDonnell P, Tullo A, Parry C.

Invest Ophthalmol Vis Sci. 2009 Aug 13. [Epub ahead of print]PMID: 19684005 [PubMed - as supplied by publisher]Related articles

Conjunctival-corneal melt in association with carotid artery stenosis.

Stewart RM, Quah SA, Nguyen DQ, Kaye SB.

Clin Ophthalmol. 2008 Sep;2(3):649-55.PMID: 19668768 [PubMed - in process]Related articlesFree article

Penetrating and Deep Anterior Lamellar Keratoplasty for keratoconus: a comparison of graft outcomes in the UK.

Jones MN, Armitage J, Ayliffe W, Larkin DF, Kaye SB.

Invest Ophthalmol Vis Sci. 2009 Aug 6. [Epub ahead of print]PMID: 19661238 [PubMed - as supplied by publisher]Related articles

Observations of reduced electron Gyroscale fluctuations in national spherical torus experiment H-mode plasmas with large ExB flow shear.

Smith DR, Kaye SM, Lee W, Mazzucato E, Park HK, Bell RE, Domier CW, Leblanc BP, Levinton FM, Luhmann NC Jr, Menard JE, Yuh H.

Phys Rev Lett. 2009 Jun 5;102(22):225005. Epub 2009 Jun 5.PMID: 19658873 [PubMed]Related articles

Methylenedioxymethamphetamine (MDMA)-related fatalities in Australia: demographics, circumstances, toxicology and major organ pathology.

Kaye S, Darke S, Duflou J.

Drug Alcohol Depend. 2009 Oct 1;104(3):254-61. Epub 2009 Jul 14.PMID: 19604654 [PubMed - indexed for MEDLINE]Related articles

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, Mortimer P, Swaisland H, Lau A, O'Connor MJ, Ashworth A, Carmichael J, Kaye SB, Schellens JH, de Bono JS.

N Engl J Med. 2009 Jul 9;361(2):123-34. Epub 2009 Jun 24.PMID: 19553641 [PubMed - indexed for MEDLINE]Related articles

A feasibility study of sequential doublet chemotherapy comprising carboplatin-doxorubicin and carboplatin-paclitaxel for advanced endometrial adenocarcinoma and carcinosarcoma.

Ang JE, Shah RN, Everard M, Keyzor C, Coombes I, Jenkins A, Thomas K, A'Hern R, Jones RL, Blake P, Gabra H, Hall G, Gore ME, Kaye SB.

Ann Oncol. 2009 Nov;20(11):1787-93. Epub 2009 Jun 19.PMID: 19542250 [PubMed - in process]Related articles

Phase 3 randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or -resistant ovarian cancer.

Vergote I, Finkler N, del Campo J, Lohr A, Hunter J, Matei D, Kavanagh J, Vermorken JB, Meng L, Jones M, Brown G, Kaye S; ASSIST-1 Study Group.

Eur J Cancer. 2009 Sep;45(13):2324-32. Epub 2009 Jun 8.PMID: 19515553 [PubMed - indexed for MEDLINE]Related articles

Phase I safety, pharmacokinetic, and pharmacogenomic trial of ES-285, a novel marine cytotoxic agent, administered to adult patients with advanced solid tumors.

Baird RD, Kitzen J, Clarke PA, Planting A, Reade S, Reid A, Welsh L, López Lázaro L, de las Heras B, Judson IR, Kaye SB, Eskens F, Workman P, deBono JS, Verweij J.

Mol Cancer Ther. 2009 Jun;8(6):1430-7. Epub 2009 Jun 9.PMID: 19509256 [PubMed - indexed for MEDLINE]Related articles

Is body mass index before middle age related to coronary heart disease risk in later life? Evidence from observational studies.

Owen CG, Whincup PH, Orfei L, Chou QA, Rudnicka AR, Wathern AK, Kaye SJ, Eriksson JG, Osmond C, Cook DG.

Int J Obes (Lond). 2009 Aug;33(8):866-77. Epub 2009 Jun 9.PMID: 19506565 [PubMed - in process]Related articles

Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer.

Attard G, Reid AH, A'Hern R, Parker C, Oommen NB, Folkerd E, Messiou C, Molife LR, Maier G, Thompson E, Olmos D, Sinha R, Lee G, Dowsett M, Kaye SB, Dearnaley D, Kheoh T, Molina A, de Bono JS.

J Clin Oncol. 2009 Aug 10;27(23):3742-8. Epub 2009 May 26.PMID: 19470933 [PubMed - indexed for MEDLINE]Related articles

Safety and efficacy of patupilone in patients with advanced ovarian, primary fallopian, or primary peritoneal cancer: a phase I, open-label, dose-escalation study.

Ten Bokkel Huinink WW, Sufliarsky J, Smit WM, Spanik S, Wagnerova M, Hirte HW, Kaye S, Johri AR, Oza AM.

J Clin Oncol. 2009 Jul 1;27(19):3097-103. Epub 2009 May 18.PMID: 19451434 [PubMed - indexed for MEDLINE]Related articles

Clinical benefit in Phase-I trials of novel molecularly targeted agents: does dose matter?

Postel-Vinay S, Arkenau HT, Olmos D, Ang J, Barriuso J, Ashley S, Banerji U, De-Bono J, Judson I, Kaye S.

Br J Cancer. 2009 May 5;100(9):1373-8.PMID: 19401696 [PubMed - indexed for MEDLINE]Related articles

Correlation between electron transport and shear Alfvén activity in the National Spherical Torus Experiment.

Stutman D, Delgado-Aparicio L, Gorelenkov N, Finkenthal M, Fredrickson E, Kaye S, Mazzucato E, Tritz K.

Phys Rev Lett. 2009 Mar 20;102(11):115002. Epub 2009 Mar 18.PMID: 19392207 [PubMed]Related articles

Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer.

Attard G, Swennenhuis JF, Olmos D, Reid AH, Vickers E, A'Hern R, Levink R, Coumans F, Moreira J, Riisnaes R, Oommen NB, Hawche G, Jameson C, Thompson E, Sipkema R, Carden CP, Parker C, Dearnaley D, Kaye SB, Cooper CS, Molina A, Cox ME, Terstappen LW, de Bono JS.

Cancer Res. 2009 Apr 1;69(7):2912-8.PMID: 19339269 [PubMed - indexed for MEDLINE]Related articles

Prospective validation of a prognostic score to improve patient selection for oncology phase I trials.

Arkenau HT, Barriuso J, Olmos D, Ang JE, de Bono J, Judson I, Kaye S.

J Clin Oncol. 2009 Jun 1;27(16):2692-6. Epub 2009 Mar 30.PMID: 19332724 [PubMed - indexed for MEDLINE]Related articles

PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.

Tan DS, Lambros MB, Rayter S, Natrajan R, Vatcheva R, Gao Q, Marchiò C, Geyer FC, Savage K, Parry S, Fenwick K, Tamber N, Mackay A, Dexter T, Jameson C, McCluggage WG, Williams A, Graham A, Faratian D, El-Bahrawy M, Paige AJ, Gabra H, Gore ME, Zvelebil M, Lord CJ, Kaye SB, Ashworth A, Reis-Filho JS.

Clin Cancer Res. 2009 Apr 1;15(7):2269-80. Epub 2009 Mar 17.PMID: 19293255 [PubMed - indexed for MEDLINE]Related articles

Approximating lens power.

Kaye SB.

Optom Vis Sci. 2009 Apr;86(4):382-94.PMID: 19258914 [PubMed - indexed for MEDLINE]Related articles

Gyrokinetic studies on turbulence-driven and neoclassical nondiffusive toroidal-momentum transport and the effect of residual fluctuations in strong E x B shear.

Wang WX, Hahm TS, Ethier S, Rewoldt G, Lee WW, Tang WM, Kaye SM, Diamond PH.

Phys Rev Lett. 2009 Jan 23;102(3):035005. Epub 2009 Jan 23.PMID: 19257365 [PubMed]Related articles

Beyond chemotherapy: targeted therapies in ovarian cancer.

Yap TA, Carden CP, Kaye SB.

Nat Rev Cancer. 2009 Mar;9(3):167-81. Review.PMID: 19238149 [PubMed - indexed for MEDLINE]Related articles

Revisiting the past: utilizing archival tissue for the detection and quantification of gene expression.

Singh S, Kaye S, Francis ND, Peston D, Gore ME, McClure MO, Bunker CB.

Br J Dermatol. 2009 Apr;160(4):885-6. Epub 2009 Feb 16. No abstract available. PMID: 19222465 [PubMed - indexed for MEDLINE]Related articles

Concentration and bioavailability of ciprofloxacin and teicoplanin in the cornea.

Kaye SB, Neal T, Nicholson S, Szkurlat J, Bamber S, Baddon AC, Anderson S, Seddon K, Dwyer N, Lovering AM, Smith G.

Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3176-84. Epub 2009 Feb 14.PMID: 19218614 [PubMed - indexed for MEDLINE]Related articles

The promises and pitfalls of epigenetic therapies in solid tumours.

Graham JS, Kaye SB, Brown R.

Eur J Cancer. 2009 May;45(7):1129-36. Epub 2009 Feb 11. Review.PMID: 19211243 [PubMed - indexed for MEDLINE]Related articles

Clinical benefit of new targeted agents in phase I trials in patients with advanced colorectal cancer.

Arkenau HT, Brunetto AT, Barriuso J, Olmos D, Eaton D, de Bono J, Judson I, Kaye S.

Oncology. 2009;76(3):151-6. Epub 2009 Jan 23.PMID: 19169046 [PubMed - indexed for MEDLINE]Related articles

From darkness to light with biomarkers in early clinical trials of cancer drugs.

Carden CP, Banerji U, Kaye SB, Workman P, de Bono JS.

Clin Pharmacol Ther. 2009 Feb;85(2):131-3. Review.PMID: 19151637 [PubMed - indexed for MEDLINE]Related articles

Localized bullous keratopathy secondary to posterior polymorphous dystrophy.

Srinivasan S, Skarmoutsos P, O'Donnell C, Kaye SB.

Clin Experiment Ophthalmol. 2008 Nov;36(8):800-1. No abstract available. PMID: 19128391 [PubMed - indexed for MEDLINE]Related articles

Birth weight and risk of type 2 diabetes: a systematic review.

Whincup PH, Kaye SJ, Owen CG, Huxley R, Cook DG, Anazawa S, Barrett-Connor E, Bhargava SK, Birgisdottir BE, Carlsson S, de Rooij SR, Dyck RF, Eriksson JG, Falkner B, Fall C, Forsén T, Grill V, Gudnason V, Hulman S, Hyppönen E, Jeffreys M, Lawlor DA, Leon DA, Minami J, Mishra G, Osmond C, Power C, Rich-Edwards JW, Roseboom TJ, Sachdev HS, Syddall H, Thorsdottir I, Vanhala M, Wadsworth M, Yarbrough DE.

JAMA. 2008 Dec 24;300(24):2886-97. Review.PMID: 19109117 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation and O2 adsorption studies of the microporous magnets CsNi[Cr(CN)6] (T(C) = 75 K) and Cr3[Cr(CN)6]2 x 6 H2O (T(N) = 219 K).

Kaye SS, Choi HJ, Long JR.

J Am Chem Soc. 2008 Dec 17;130(50):16921-5.PMID: 19053438 [PubMed]Related articles

A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants.

Pizzato M, Erlwein O, Bonsall D, Kaye S, Muir D, McClure MO.

J Virol Methods. 2009 Mar;156(1-2):1-7. Epub 2008 Dec 5.PMID: 19022294 [PubMed - indexed for MEDLINE]Related articles

HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection.

Duda A, Lee-Turner L, Fox J, Robinson N, Dustan S, Kaye S, Fryer H, Carrington M, McClure M, McLean AR, Fidler S, Weber J, Phillips RE, Frater AJ; SPARTAC Trial Investigators.

J Virol. 2009 Feb;83(3):1228-39. Epub 2008 Nov 19.PMID: 19019964 [PubMed - indexed for MEDLINE]Related articlesFree article

Ligneous conjunctivitis with plasminogen deficiency.

Thachil J, Reeves G, Kaye S.

Br J Haematol. 2009 May;145(3):269. No abstract available. PMID: 19006564 [PubMed - indexed for MEDLINE]Related articles

Neurological morbidity among human T-lymphotropic-virus-type-1-infected individuals in a rural West African population.

Cooper S, van der Loeff MS, McConkey S, Cooper M, Sarge-Njie R, Kaye S, Whittle H.

J Neurol Neurosurg Psychiatry. 2009 Jan;80(1):66-8. Epub 2008 Oct 31.PMID: 18977823 [PubMed - indexed for MEDLINE]Related articles

"BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations.

Tan DS, Rothermundt C, Thomas K, Bancroft E, Eeles R, Shanley S, Ardern-Jones A, Norman A, Kaye SB, Gore ME.

J Clin Oncol. 2008 Dec 1;26(34):5530-6. Epub 2008 Oct 27.PMID: 18955455 [PubMed - indexed for MEDLINE]Related articles

Phase I pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors.

de Bono JS, Kristeleit R, Tolcher A, Fong P, Pacey S, Karavasilis V, Mita M, Shaw H, Workman P, Kaye S, Rowinsky EK, Aherne W, Atadja P, Scott JW, Patnaik A.

Clin Cancer Res. 2008 Oct 15;14(20):6663-73.PMID: 18927309 [PubMed - indexed for MEDLINE]Related articlesFree article

Methamphetamine-related fatalities in Australia: demographics, circumstances, toxicology and major organ pathology.

Kaye S, Darke S, Duflou J, McKetin R.

Addiction. 2008 Aug;103(8):1353-60.PMID: 18855825 [PubMed - indexed for MEDLINE]Related articles

The visual and refractive outcomes of combined and sequential penetrating keratoplasty, cataract extraction, and intraocular lens insertion.

Nguyen DQ, Mumford LL, Jones MN, Armitage WJ, Cook SD, Kaye SB, Tole DM.

Eye (Lond). 2009 Jun;23(6):1295-301. Epub 2008 Oct 3.PMID: 18836407 [PubMed - in process]Related articles

Short-scale turbulent fluctuations driven by the electron-temperature gradient in the national spherical torus experiment.

Mazzucato E, Smith DR, Bell RE, Kaye SM, Hosea JC, LeBlanc BP, Wilson JR, Ryan PM, Domier CW, Luhmann NC Jr, Yuh H, Lee W, Park H.

Phys Rev Lett. 2008 Aug 15;101(7):075001. Epub 2008 Aug 11.PMID: 18764544 [PubMed]Related articles

Momentum-transport studies in high E x B shear plasmas in the National Spherical Torus Experiment.

Solomon WM, Kaye SM, Bell RE, Leblanc BP, Menard JE, Rewoldt G, Wang W, Levinton FM, Yuh H, Sabbagh SA.

Phys Rev Lett. 2008 Aug 8;101(6):065004. Epub 2008 Aug 7.PMID: 18764464 [PubMed]Related articles

Does initial breastfeeding lead to lower blood cholesterol in adult life? A quantitative review of the evidence.

Owen CG, Whincup PH, Kaye SJ, Martin RM, Davey Smith G, Cook DG, Bergstrom E, Black S, Wadsworth ME, Fall CH, Freudenheim JL, Nie J, Huxley RR, Kolacek S, Leeson CP, Pearce MS, Raitakari OT, Lisinen I, Viikari JS, Ravelli AC, Rudnicka AR, Strachan DP, Williams SM.

Am J Clin Nutr. 2008 Aug;88(2):305-14. Review. Erratum in: Am J Clin Nutr. 2008 Dec;88(6):1707. PMID: 18689365 [PubMed - indexed for MEDLINE]Related articlesFree article

Maintenance of large subpopulations of differentiated CD8 T-cells two years after cytomegalovirus infection in Gambian infants.

Miles DJ, van der Sande M, Jeffries D, Kaye S, Ojuola O, Sanneh M, Cox M, Palmero MS, Touray ES, Waight P, Rowland-Jones S, Whittle H, Marchant A.

PLoS One. 2008 Aug 6;3(8):e2905.PMID: 18682836 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotypic analysis of two hypervariable human cytomegalovirus genes.

Bradley AJ, Kovács IJ, Gatherer D, Dargan DJ, Alkharsah KR, Chan PK, Carman WF, Dedicoat M, Emery VC, Geddes CC, Gerna G, Ben-Ismaeil B, Kaye S, McGregor A, Moss PA, Pusztai R, Rawlinson WD, Scott GM, Wilkinson GW, Schulz TF, Davison AJ.

J Med Virol. 2008 Sep;80(9):1615-23.PMID: 18649324 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.

Attard G, Reid AH, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper CS, Kaye SB, Dearnaley D, Lee G, de Bono JS.

J Clin Oncol. 2008 Oct 1;26(28):4563-71. Epub 2008 Jul 21.PMID: 18645193 [PubMed - indexed for MEDLINE]Related articles

Genotypic antiretroviral drug resistance testing at low viral loads in the UK.

Cane PA, Kaye S, Smit E, Tilston P, Kirk S, Shepherd J, Hopkins M, Zhang H, Geretti AM.

HIV Med. 2008 Oct;9(8):673-6. Epub 2008 Jun 28.PMID: 18557948 [PubMed - indexed for MEDLINE]Related articles

90-Days mortality rate in patients treated within the context of a phase-I trial: how should we identify patients who should not go on trial?

Arkenau HT, Olmos D, Ang JE, Barriuso J, Karavasilis V, Ashley S, de Bono J, Judson I, Kaye S.

Eur J Cancer. 2008 Jul;44(11):1536-40. Epub 2008 Jun 10.PMID: 18550361 [PubMed - indexed for MEDLINE]Related articles