PubMed

Risk assessment and communication tools for genotype associations with multifactorial phenotypes: the concept of "edge effect" and cultivating an ethical bridge between omics innovations and society.

Ozdemir V, Suarez-Kurtz G, Stenne R, Somogyi AA, Someya T, Kayaalp SO, Kolker E.

OMICS. 2009 Feb;13(1):43-61.PMID: 19290811 [PubMed - indexed for MEDLINE]Related articlesFree article

CYP2C9 genetic variants and losartan oxidation in a Turkish population.

Babaoglu MO, Yasar U, Sandberg M, Eliasson E, Dahl ML, Kayaalp SO, Bozkurt A.

Eur J Clin Pharmacol. 2004 Jul;60(5):337-42. Epub 2004 Jun 10.PMID: 15197523 [PubMed - indexed for MEDLINE]Related articles

Frequency and enzyme activity of the butyrylcholinesterase K-variant in a Turkish population.

Babaoglu MO, Ocal T, Bayar B, Kayaalp SO, Bozkurt A.

Eur J Clin Pharmacol. 2004 Feb;59(12):875-7. Epub 2004 Jan 21.PMID: 14735258 [PubMed - indexed for MEDLINE]Related articles

Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers.

Kortunay S, Bozkurt A, Basci NE, Kayaalp SO.

Eur J Drug Metab Pharmacokinet. 2002 Jul-Sep;27(3):171-4.PMID: 12365197 [PubMed - indexed for MEDLINE]Related articles

Dose-dependent inhibition of the CYP2D6 catalyzed oxidation of sparteine by mepyramine in healthy volunteers.

Kortunay S, Bozkurt A, Basci NE, Brøsen K, Kayaalp SO.

Pharmacol Toxicol. 2001 Dec;89(6):331-4. No abstract available. PMID: 11903961 [PubMed - indexed for MEDLINE]Related articles

N-acetyltransferase polymorphism in patients with Behçet's disease.

Aynacioglu AS, Bozkurt A, Nacak M, Kortunay S, Tunc R, Dincel A, Kayaalp SO.

Eur J Clin Pharmacol. 2001 Nov;57(9):659-62.PMID: 11791896 [PubMed - indexed for MEDLINE]Related articles

Comparison of subretinal fluid levels of two 0.3% ciprofloxacin-containing eye drops.

Cekiç O, Batman C, Yaşar U, Totan Y, Başci NE, Bozkurt A, Zilelioglu O, Kayaalp SO.

Clin Experiment Ophthalmol. 2001 Feb;29(1):30-2.PMID: 11272782 [PubMed - indexed for MEDLINE]Related articles

Aqueous humour levels of topically applied ciprofloxacin and ofloxacin in the same subjects.

Cekiç O, Batman C, Totan Y, Yasar U, Basci NE, Bozkurt A, Kayaalp SO, Zilelioglu O.

Eye (Lond). 1999 Oct;13 ( Pt 5):656-9.PMID: 10696321 [PubMed - indexed for MEDLINE]Related articles

Human aqueous and vitreous humour levels of ciprofloxacin following oral and topical administration.

Cekiç O, Batman C, Yasar U, Başci NE, Bozkurt A, Kayaalp SO.

Eye (Lond). 1999 Aug;13 ( Pt 4):555-8.PMID: 10692930 [PubMed - indexed for MEDLINE]Related articles

Penetration of topical, oral, and combined administered ofloxacin into the subretinal fluid.

Cekiç O, Batman C, Yasar U, Totan Y, Basci NE, Bozkurt A, Zilelioglu O, Kayaalp SO.

Br J Ophthalmol. 1999 Oct;83(10):1183-5.PMID: 10502583 [PubMed - indexed for MEDLINE]Related articlesFree article

Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population.

Aynacioglu AS, Sachse C, Bozkurt A, Kortunay S, Nacak M, Schröder T, Kayaalp SO, Roots I, Brockmöller J.

Clin Pharmacol Ther. 1999 Aug;66(2):185-92.PMID: 10460072 [PubMed - indexed for MEDLINE]Related articles

Penetration of ofloxacin and ciprofloxacin in aqueous humor after topical administration.

Cekiç O, Batman C, Totan Y, Yasar U, Basci NE, Bozkurt A, Kayaalp SO.

Ophthalmic Surg Lasers. 1999 Jun;30(6):465-8.PMID: 10392734 [PubMed - indexed for MEDLINE]Related articles

CYP2C19 genotype does not represent a genetic predisposition in idiopathic systemic lupus erythematosus.

Kortunay S, Bozkurt A, Bathum L, Basci NE, Calgüneri M, Brøsen K, Kayaalp SO.

Ann Rheum Dis. 1999 Mar;58(3):182-5.PMID: 10364917 [PubMed - indexed for MEDLINE]Related articlesFree article

CYP2D6 polymorphism in systemic lupus erythematosus patients.

Kortunay S, Bozkurt A, Bathum L, Basci NE, Calgüneri M, Brøsen K, Kayaalp SO.

Eur J Clin Pharmacol. 1999 Mar;55(1):21-5.PMID: 10206080 [PubMed - indexed for MEDLINE]Related articles

Comparison of aqueous humour and vitreous humour levels of two 0.3% ciprofloxacin eyedrops.

Cekiç O, Batman C, Yasar U, Basci NE, Bozkurt A, Kayaalp SO.

Can J Ophthalmol. 1998 Dec;33(7):373-6.PMID: 9885752 [PubMed - indexed for MEDLINE]Related articles

Penetration of ofloxacin in human aqueous and vitreous humors following oral and topical administration.

Cekic O, Batman C, Yasar U, Basci NE, Bozkurt A, Kayaalp SO.

Retina. 1998;18(6):521-5.PMID: 9869460 [PubMed - indexed for MEDLINE]Related articles

Omission of the deconjugation step in urine analysis and the unaltered outcome of CYP2D6 phenotyping with dextromethorphan.

Basci NE, Bozkurt A, Kayaalp SO, Sayal A, Isimer A.

Eur J Drug Metab Pharmacokinet. 1998 Jan-Mar;23(1):1-5.PMID: 9625265 [PubMed - indexed for MEDLINE]Related articles

Determination of ofloxacin in human aqueous humour by high-performance liquid chromatography with fluorescence detection.

Basci NE, Hanioglu-Kargi S, Soysal H, Bozkurt A, Kayaalp SO.

J Pharm Biomed Anal. 1997 Feb;15(5):663-6.PMID: 9127278 [PubMed - indexed for MEDLINE]Related articles

The hydroxylation of omeprazole correlates with S-mephenytoin and proguanil metabolism.

Kortunay S, Basci NE, Bozkurt A, Isimer A, Sayal A, Kayaalp SO.

Eur J Clin Pharmacol. 1997;53(3-4):261-4.PMID: 9476042 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide synthase inhibition attenuates signs of ethanol withdrawal in rats.

Uzbay IT, Erden BF, Tapanyigit EE, Kayaalp SO.

Life Sci. 1997;61(22):2197-209.PMID: 9393939 [PubMed - indexed for MEDLINE]Related articles

Proguanil metabolism in relation to S-mephenytoin oxidation in a Turkish population.

Basci NE, Bozkurt A, Kortunay S, Isimer A, Sayal A, Kayaalp SO.

Br J Clin Pharmacol. 1996 Dec;42(6):771-3.PMID: 8971434 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic ratios of four probes of CYP2D6 in Turkish subjects: a cross-over study.

Bozkurt A, Basçi NE, Işimer A, Sayal A, Kayaalp SO.

Eur J Drug Metab Pharmacokinet. 1996 Oct-Dec;21(4):309-14.PMID: 9074895 [PubMed - indexed for MEDLINE]Related articles

A study on the mediators of antidromic vasodilatation elicited by sciatic nerve stimulation in cats.

Küçükhüseyin C, Kayaalp SO.

J Basic Clin Physiol Pharmacol. 1996;7(4):363-73.PMID: 9080310 [PubMed - indexed for MEDLINE]Related articles

Rapid liquid chromatographic assay of ciprofloxacin in human aqueous humor.

Basci NE, Bozkurt A, Kalayci D, Kayaalp SO.

J Pharm Biomed Anal. 1996 Jan;14(3):353-6.PMID: 8851760 [PubMed - indexed for MEDLINE]Related articles

Heterogeneity of tolerance developed to effects of ethanol on rotarod and accelerod performances in rats.

Uzbay IT, Kayaalp SO.

Alcohol. 1995 Nov-Dec;12(6):593-5.PMID: 8590625 [PubMed - indexed for MEDLINE]Related articles

Effect of nitrovasodilators on the rhythmic contractions of guinea-pig isolated sphincter of Oddi.

Göçer F, Yariş E, Tuncer M, Kayaalp SO.

Arzneimittelforschung. 1995 Jul;45(7):809-12.PMID: 8573227 [PubMed - indexed for MEDLINE]Related articles

Effects of flumazenil on ethanol withdrawal syndrome in rats.

Uzbay IT, Akarsu ES, Kayaalp SO.

Arzneimittelforschung. 1995 Feb;45(2):120-4.PMID: 7710430 [PubMed - indexed for MEDLINE]Related articles

A modified liquid diet of chronic ethanol administration: validation by ethanol withdrawal syndrome in rats.

Uzbay IT, Kayaalp SO.

Pharmacol Res. 1995 Jan;31(1):37-42.PMID: 7784304 [PubMed - indexed for MEDLINE]Related articles

Effects of bromocriptine and haloperidol on ethanol withdrawal syndrome in rats.

Uzbay IT, Akarsu ES, Kayaalp SO.

Pharmacol Biochem Behav. 1994 Dec;49(4):969-74.PMID: 7886115 [PubMed - indexed for MEDLINE]Related articles

Effect of changes in swimming area on results of "behavioral despair test".

Sunal R, Gümüşel B, Kayaalp SO.

Pharmacol Biochem Behav. 1994 Dec;49(4):891-6.PMID: 7886103 [PubMed - indexed for MEDLINE]Related articles

S-mephenytoin, sparteine and debrisoquine oxidation: genetic polymorphisms in a Turkish population.

Basci NE, Brosen K, Bozkurt A, Isimer A, Sayal A, Kayaalp SO.

Br J Clin Pharmacol. 1994 Nov;38(5):463-5.PMID: 7893589 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation between the metabolic ratios of debrisoquine and metoprolol in Turkish subjects.

Basci NE, Bozkurt A, Isimer A, Kayaalp SO.

Pharmacol Toxicol. 1994 Jul;75(1):62-4. No abstract available. PMID: 7971736 [PubMed - indexed for MEDLINE]Related articles

Polymorphic debrisoquin metabolism in a Turkish population.

Bozkurt A, Basci NE, Isimer A, Sayal A, Kayaalp SO.

Clin Pharmacol Ther. 1994 Apr;55(4):399-401.PMID: 8162666 [PubMed - indexed for MEDLINE]Related articles

Direct vascular smooth muscle contractile effect of cyclosporin A and its vehicle in rabbit isolated arteries.

Yariş E, Tuncer M, Kayaalp SO, Ilhan M.

Arch Int Pharmacodyn Ther. 1994 Mar-Apr;327(2):166-74.PMID: 7979825 [PubMed - indexed for MEDLINE]Related articles

Determination of debrisoquine and 4-hydroxydebrisoquine in urine by high-performance liquid chromatography with fluorescence detection after solid-phase extraction.

Bozkurt A, Basci NE, Isimer A, Kayaalp SO.

J Pharm Biomed Anal. 1993 Aug;11(8):745-9.PMID: 8257740 [PubMed - indexed for MEDLINE]Related articles

Heterogeneity of 5-HT responsiveness in different segments of rabbit arteries.

Tuncer M, Yariş E, Kayaalp SO.

Arch Int Physiol Biochim Biophys. 1992 Mar-Apr;100(2):159-64.PMID: 1379494 [PubMed - indexed for MEDLINE]Related articles

Comparison of the cardiovascular effects of amineptine with those of amitriptyline and imipramine in anaesthetized rats.

Balcioglu A, Bozkurt A, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1991 Jan-Feb;309:64-74.PMID: 1888231 [PubMed - indexed for MEDLINE]Related articles

Antagonism of acetylcholine action in guinea-pig tracheal smooth muscle and epithelium by pirenzepine, 4-DAMP and atropine.

Orer HS, Guc MO, Rezaki YE, Ilhan M, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1990 May-Jun;305:45-54.PMID: 2241429 [PubMed - indexed for MEDLINE]Related articles

Comparison of colorimetric and high-performance liquid chromatographic determination of sulphamethoxazole and acetylsulphamethoxazole.

Basci NE, Bozkurt A, Kayaalp SO, Isimer A.

J Chromatogr. 1990 Apr 27;527(1):174-81. No abstract available. PMID: 2365777 [PubMed - indexed for MEDLINE]Related articles

Sulphamethoxazole acetylation in fast and slow acetylators.

Bozkurt A, Basci NE, Isimer A, Tuncer M, Erdal R, Kayaalp SO.

Int J Clin Pharmacol Ther Toxicol. 1990 Apr;28(4):164-6.PMID: 2338369 [PubMed - indexed for MEDLINE]Related articles

N-acetylation phenotyping with sulphadimidine in a Turkish population.

Bozkurt A, Basci NE, Kalan S, Tuncer M, Kayaalp SO.

Eur J Clin Pharmacol. 1990;38(1):53-6.PMID: 2328748 [PubMed - indexed for MEDLINE]Related articles

Epithelium-dependent relaxation of guinea-pig tracheal smooth muscle by histamine: evidence for non-H1- and non-H2-histamine receptors.

Guc MO, Ilhan M, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1988 Nov-Dec;296:57-65.PMID: 3240022 [PubMed - indexed for MEDLINE]Related articles

Epithelium-dependent relaxation of guinea-pig tracheal smooth muscle by carbachol.

Guc MO, Ilhan M, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1988 Jul-Aug;294:241-7.PMID: 3233050 [PubMed - indexed for MEDLINE]Related articles

The rat anococcygeus muscle is a convenient bioassay organ for the airway epithelium-derived relaxant factor.

Güc MO, Ilhan M, Kayaalp SO.

Eur J Pharmacol. 1988 Apr 13;148(3):405-9.PMID: 3260190 [PubMed - indexed for MEDLINE]Related articles

Influence of temperature on the responses to serotonin (5-HT) in perfused rat lung.

Uma S, Tuncer M, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1988 Mar-Apr;292:248-57.PMID: 3395171 [PubMed - indexed for MEDLINE]Related articles

An evidence for presynaptic excitatory alpha 2-adrenergic receptors in frog myocardium.

Sarioğlu Y, Ilhan M, Kayaalp SO.

Arch Int Physiol Biochim. 1988 Mar;96(1):35-40.PMID: 2460047 [PubMed - indexed for MEDLINE]Related articles

The subtype of serotonin (5-HT) receptors in the rat pulmonary artery.

Uma S, Tuncer M, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1987 Aug;288(2):248-55.PMID: 3675084 [PubMed - indexed for MEDLINE]Related articles

Effect of naloxone on physostigmine-induced pressor response in adrenalectomized rats.

Oktay S, Onur R, Ilhan M, Kayaalp SO.

Arch Int Physiol Biochim. 1987 Jun;95(2):141-5.PMID: 2444181 [PubMed - indexed for MEDLINE]Related articles

Surgical stress inhibits physostigmine-induced pressor effect.

Oktay S, Onur R, Ilhan M, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1986 Oct;283(2):237-42.PMID: 3789886 [PubMed - indexed for MEDLINE]Related articles

Are there any presynaptic 5-HT receptors in frog atria?

Sahin I, Onur R, Tuncer M, Kayaalp SO.

Arch Int Pharmacodyn Ther. 1986 Jul;282(1):82-92.PMID: 3021075 [PubMed - indexed for MEDLINE]Related articles