PubMed

Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents.

Arakawa M, Ebato C, Mita T, Hirose T, Kawamori R, Fujitani Y, Watada H.

Biochem Biophys Res Commun. 2009 Oct 21. [Epub ahead of print]PMID: 19836346 [PubMed - as supplied by publisher]Related articles

Long-term effects of pioglitazone in Japanese patients with type 2 diabetes without a recent history of macrovascular morbidity.

Kaku K, Daida H, Kashiwagi A, Yamashina A, Yamazaki T, Momomura S, Iwase T, Yamasaki Y, Nagatsuka K, Kitagawa K, Kawamori R.

Curr Med Res Opin. 2009 Dec;25(12):2925-32.PMID: 19835463 [PubMed - in process]Related articles

Risk for nocturnal hypoglycemia with biphasic insulin aspart 30 compared with biphasic human insulin 30 in adults with type 2 diabetes mellitus: a meta-analysis.

Davidson JA, Liebl A, Christiansen JS, Fulcher G, Ligthelm RJ, Brown P, Gylvin T, Kawamori R.

Clin Ther. 2009 Aug;31(8):1641-51.PMID: 19808125 [PubMed - in process]Related articles

[Alpha-glucosidase inhibitor for the prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese subjects with impaired glucose tolerance]

Kawamori R, Tajima N, Iwamoto Y, Kashiwagi A, Shimamoto K, Kaku K.

Nippon Rinsho. 2009 Sep;67(9):1821-5. Japanese. PMID: 19768922 [PubMed - in process]Related articles

Improved glycaemic control with BIAsp 30 in insulin-naïve type 2 diabetes patients inadequately controlled on oral antidiabetics: subgroup analysis from the IMPROVE study.

Wenying Y, Benroubi M, Borzi V, Gumprecht J, Kawamori R, Shaban J, Shah S, Shestakova M, Ligthelm R, Valensi P; IMPROVE Study Group Expert Panel.

Curr Med Res Opin. 2009 Nov;25(11):2643-54.PMID: 19751116 [PubMed - in process]Related articles

Preliminary report: mitochondrial DNA 5178 polymorphism in male elite Japanese endurance runners.

Tamura Y, Watada H, Tanaka Y, Daimaru N, Nomiyama T, Sakuraba K, Sawaki K, Kawamori R.

Metabolism. 2009 Aug 28. [Epub ahead of print]PMID: 19717174 [PubMed - as supplied by publisher]Related articles

Effect of sulfonylureas on switching to insulin therapy (twice-daily biphasic insulin aspart 30): comparison of twice-daily biphasic insulin aspart 30 with or without glimepiride in type 2 diabetic patients poorly controlled with sub-maximal glimepiride.

Ebato C, Shimizu T, Arakawa M, Mita T, Fujitani Y, Watada H, Kawamori R, Hirose T.

Diabetes Res Clin Pract. 2009 Oct;86(1):31-6. Epub 2009 Aug 18.PMID: 19692134 [PubMed - in process]Related articles

Clinical efficacy of basic fibroblast growth factor (bFGF) for diabetic ulcer.

Uchi H, Igarashi A, Urabe K, Koga T, Nakayama J, Kawamori R, Tamaki K, Hirakata H, Ohura T, Furue M.

Eur J Dermatol. 2009 Sep 1;19(5):461-468. Epub 2009 Jul 29.PMID: 19638336 [PubMed - as supplied by publisher]Related articles

Efficacy and safety of insulin glulisine in Japanese patients with type 1 diabetes mellitus.

Kawamori R, Kadowaki T, Ishii H, Iwasaki M, Iwamoto Y.

Diabetes Obes Metab. 2009 Sep;11(9):891-9. Epub 2009 Jul 13.PMID: 19614947 [PubMed - in process]Related articles

Effects of insulin glulisine as mono- or add-on therapy in patients with type 2 diabetes mellitus.

Kawamori R, Iwamoto Y, Kadowaki T, Iwasaki M, Kim SW, Woo JT, Baik SH, Yoon KH.

Diabetes Obes Metab. 2009 Sep;11(9):900-9. Epub 2009 Jul 13.PMID: 19614946 [PubMed - in process]Related articles

Cardiovascular events in Japanese asymptomatic patients with type 2 diabetes: a 1-year interim report of a J-ACCESS 2 investigation using myocardial perfusion imaging.

Nakajima K, Yamasaki Y, Kusuoka H, Izumi T, Kashiwagi A, Kawamori R, Shimamoto K, Yamada N, Nishimura T.

Eur J Nucl Med Mol Imaging. 2009 Jul 11. [Epub ahead of print]PMID: 19593560 [PubMed - as supplied by publisher]Related articles

Morning home blood pressure may be a significant marker of nephropathy in Japanese patients with type 2 diabetes: ADVANCED-J study 1.

Tanaka Y, Daida H, Imai Y, Miyauchi K, Sato Y, Hiwatari M, Kitagawa A, Kishimoto J, Yamazaki T, Kawamori R.

Hypertens Res. 2009 Sep;32(9):770-4. Epub 2009 Jun 26.PMID: 19557003 [PubMed - in process]Related articles

Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy.

Abe H, Mita T, Kudo K, Funayama T, Tokoro M, Kaga H, Ikeda F, Kanazawa A, Hirose T, Kawamori R, Wada H.

Endocr J. 2009;56(7):911-3. Epub 2009 Jun 9.PMID: 19506327 [PubMed - in process]Related articlesFree article

Intensification to biphasic insulin aspart 30/70 (BIAsp 30, NovoMix 30) can improve glycaemic control in patients treated with basal insulins: a subgroup analysis of the IMPROVE observational study.

Gumprecht J, Benroubi M, Borzi V, Kawamori R, Shaban J, Shah S, Shestakova M, Wenying Y, Ligthelm R, Valensi P; IMPROVE Study Group Expert Panel.

Int J Clin Pract. 2009 Jun;63(6):966-72.PMID: 19504715 [PubMed - in process]Related articlesFree article

Combined effect of oxidative stress-related gene polymorphisms on the progression of carotid atherosclerosis in Japanese type 2 diabetes.

Katakami N, Saito M, Kaneto H, Matsuhisa M, Kawamori R, Osonoi T, Yamasaki Y.

Atherosclerosis. 2009 Nov;207(1):29-31. Epub 2009 May 4. No abstract available. PMID: 19486980 [PubMed - in process]Related articles

Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals.

Omori S, Tanaka Y, Horikoshi M, Takahashi A, Hara K, Hirose H, Kashiwagi A, Kaku K, Kawamori R, Kadowaki T, Nakamura Y, Maeda S.

Diabetologia. 2009 Aug;52(8):1554-60. Epub 2009 May 20.PMID: 19455301 [PubMed - indexed for MEDLINE]Related articles

Cumulative effect of oxidative stress-related gene polymorphisms on myocardial infarction in type 2 diabetes.

Katakami N, Sakamoto K, Kaneto H, Matsuhisa M, Ohno K, Shimizu I, Ishibashi F, Osonoi T, Kashiwagi A, Kawamori R, Yamasaki Y.

Diabetes Care. 2009 May;32(5):e55. No abstract available. PMID: 19407065 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the connexin37 polymorphism and peripheral arterial disease in subjects with type 2 diabetes.

Katakami N, Sakamoto K, Kaneto H, Matsuhisa M, Shimizu I, Ishibashi F, Osonoi T, Kashiwagi A, Kawamori R, Hori M, Yamasaki Y.

Diabetes Care. 2009 May;32(5):e53-4. No abstract available. PMID: 19407064 [PubMed - indexed for MEDLINE]Related articlesFree article

Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance.

Kawamori R, Tajima N, Iwamoto Y, Kashiwagi A, Shimamoto K, Kaku K; Voglibose Ph-3 Study Group.

Lancet. 2009 May 9;373(9675):1607-14. Epub 2009 Apr 22.PMID: 19395079 [PubMed - indexed for MEDLINE]Related articles

Normal islet vascularization is dispensable for expansion of beta-cell mass in response to high-fat diet induced insulin resistance.

Toyofuku Y, Uchida T, Nakayama S, Hirose T, Kawamori R, Fujitani Y, Inoue M, Watada H.

Biochem Biophys Res Commun. 2009 Jun 5;383(3):303-7. Epub 2009 Mar 29.PMID: 19336220 [PubMed - indexed for MEDLINE]Related articles

Presence of alpha-smooth muscle actin-positive endothelial cells in the luminal surface of adult aorta.

Azuma K, Ichimura K, Mita T, Nakayama S, Jin WL, Hirose T, Fujitani Y, Sumiyoshi K, Shimada K, Daida H, Sakai T, Mitsumata M, Kawamori R, Watada H.

Biochem Biophys Res Commun. 2009 Mar 13;380(3):620-6. Epub 2009 Jan 27.PMID: 19285011 [PubMed - indexed for MEDLINE]Related articles

Association between atherosclerosis and newly classified chronic kidney disease stage for Japanese patients with type 2 diabetes.

Yamamoto R, Kanazawa A, Shimizu T, Hirose T, Tanaka Y, Kawamori R, Watada H.

Diabetes Res Clin Pract. 2009 Apr;84(1):39-45. Epub 2009 Feb 14.PMID: 19223087 [PubMed - indexed for MEDLINE]Related articles

Safety and effectiveness of biphasic insulin aspart 30/70 (NovoMix 30) when switching from human premix insulin in patients with type 2 diabetes: subgroup analysis from the 6-month IMPROVE observational study.

Shah S, Benroubi M, Borzi V, Gumprecht J, Kawamori R, Shaban J, Shestakova M, Wenying Y, Valensi P; IMPROVE Study Group Expert Panel.

Int J Clin Pract. 2009 Apr;63(4):574-82. Epub 2009 Feb 5.PMID: 19210701 [PubMed - indexed for MEDLINE]Related articlesFree article

Initiating insulin therapy with, or switching existing insulin therapy to, biphasic insulin aspart 30/70 (NovoMix 30) in routine care: safety and effectiveness in patients with type 2 diabetes in the IMPROVE observational study.

Valensi P, Benroubi M, Borzi V, Gumprecht J, Kawamori R, Shaban J, Shah S, Shestakova M, Wenying Y; IMPROVE Study Group Expert Panel.

Int J Clin Pract. 2009 Mar;63(3):522-31. Epub 2009 Jan 27.PMID: 19187170 [PubMed - indexed for MEDLINE]Related articles

Prevalence of abnormal glucose metabolism and insulin resistance among subtypes of ischemic stroke in Japanese patients.

Urabe T, Watada H, Okuma Y, Tanaka R, Ueno Y, Miyamoto N, Tanaka Y, Hattori N, Kawamori R.

Stroke. 2009 Apr;40(4):1289-95. Epub 2009 Jan 22.PMID: 19164796 [PubMed - indexed for MEDLINE]Related articles

The role of autophagy in pancreatic beta-cell and diabetes.

Fujitani Y, Kawamori R, Watada H.

Autophagy. 2009 Feb;5(2):280-2. Epub 2009 Feb 19.PMID: 19158492 [PubMed - indexed for MEDLINE]Related articles

Combined effect of oxidative stress-related gene polymorphisms on atherosclerosis.

Katakami N, Sakamoto K, Kaneto H, Matsuhisa M, Shimizu I, Ishibashi F, Osonoi T, Kashiwagi A, Kawamori R, Hori M, Yamasaki Y.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):861-5. Epub 2009 Jan 4.PMID: 19126404 [PubMed - indexed for MEDLINE]Related articles

OMEGA study: design, baseline data, metabolic syndrome prevalence in a large-scale observational study of hypertensive patients: The Olmesartan Mega Study to Determine the Relationship between Cardiovascular Endpoints and Blood Pressure Goal Achievement study.

Teramoto T, Fujita T, Kawamori R, Miyazaki S, Teramukai S, Igarashi M.

Hypertens Res. 2008 Nov;31(11):2011-7.PMID: 19098372 [PubMed - indexed for MEDLINE]Related articles

Relation between cardiovascular complications and blood pressure/blood glucose control in diabetic patients with hypertension receiving long-term candesartan cilexetil therapy: Challenge-DM study.

Kawamori R, Fujita T, Matsuoka H, Umemura S, Saito Y.

Diabetes Res Clin Pract. 2009 Feb;83(2):241-8. Epub 2008 Dec 20.PMID: 19097664 [PubMed - indexed for MEDLINE]Related articles

Rationale and design of the carotid plaque in human for all evaluations with aggressive rosuvastatin therapy (CHALLENGER trial): evaluation by magnetic resonance imaging.

Miyauchi K, Takaya N, Hirose T, Ikeda F, Kawamori R, Ohishi H, Yoshida K, Yamamoto M, Arai H, Urabe T, Hattori N, Suzuki M, Maehara T, Sase K, Hatsukami TS, Yuan C, Daida H.

Circ J. 2009 Jan;73(1):111-5. Epub 2008 Dec 4.PMID: 19057091 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibitor, epalrestat, reduces lipid hydroperoxides in type 2 diabetes.

Ohmura C, Watada H, Azuma K, Shimizu T, Kanazawa A, Ikeda F, Yoshihara T, Fujitani Y, Hirose T, Tanaka Y, Kawamori R.

Endocr J. 2009 Mar;56(1):149-56. Epub 2008 Nov 8.PMID: 18997444 [PubMed - indexed for MEDLINE]Related articlesFree article

In half of hypertensive diabetics, co-administration of a calcium channel blocker and an angiotensin-converting enzyme inhibitor achieved a target blood pressure of <130/80 mmHg: the azelnidipine and temocapril in hypertensive patients with type 2 diabetes (ATTEST) study.

Katayama S, Kawamori R, Iwamoto Y, Saito I, Kuramoto K; ATTEST Study Group.

Hypertens Res. 2008 Aug;31(8):1499-508.PMID: 18971523 [PubMed - indexed for MEDLINE]Related articles

Letter by Watada et al regarding article, "Two-year clinical outcomes with drug-eluting stents for diabetic patients with de novo coronary lesion".

Watada H, Daida H, Kawamori R.

Circulation. 2008 Oct 28;118(18):e680; author reply e681. No abstract available. PMID: 18955674 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of whole body irradiation and vascular endothelial growth factor-A on increased beta cell mass after bone marrow transplantation in a mouse model of diabetes induced by streptozotocin.

Nakayama S, Uchida T, Choi JB, Fujitani Y, Ogihara T, Iwashita N, Azuma K, Mochizuki H, Hirose T, Kawamori R, Inoue M, Watada H.

Diabetologia. 2009 Jan;52(1):115-24. Epub 2008 Oct 23.PMID: 18946656 [PubMed - indexed for MEDLINE]Related articles

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet.

Ebato C, Uchida T, Arakawa M, Komatsu M, Ueno T, Komiya K, Azuma K, Hirose T, Tanaka K, Kominami E, Kawamori R, Fujitani Y, Watada H.

Cell Metab. 2008 Oct;8(4):325-32.PMID: 18840363 [PubMed - indexed for MEDLINE]Related articles

The IMPROVE study--a multinational, observational study in type 2 diabetes: baseline characteristics from eight national cohorts.

Valensi P, Benroubi M, Borzi V, Gumprecht J, Kawamori R, Shaban J, Shah S, Shestakova M, Wenying Y; IMPROVE Study Group Expert Panel.

Int J Clin Pract. 2008 Nov;62(11):1809-19. Epub 2008 Sep 22. Erratum in: Int J Clin Pract. 2009 Mar;63(3):532. PMID: 18811598 [PubMed - indexed for MEDLINE]Related articles

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, Andersen G, Ng DP, Holmkvist J, Borch-Johnsen K, Jørgensen T, Sandbaek A, Lauritzen T, Hansen T, Nurbaya S, Tsunoda T, Kubo M, Babazono T, Hirose H, Hayashi M, Iwamoto Y, Kashiwagi A, Kaku K, Kawamori R, Tai ES, Pedersen O, Kamatani N, Kadowaki T, Kikkawa R, Nakamura Y, Maeda S.

Nat Genet. 2008 Sep;40(9):1098-102.PMID: 18711366 [PubMed - indexed for MEDLINE]Related articles

Miglitol suppresses the postprandial increase in interleukin 6 and enhances active glucagon-like peptide 1 secretion in viscerally obese subjects.

Arakawa M, Ebato C, Mita T, Fujitani Y, Shimizu T, Watada H, Kawamori R, Hirose T.

Metabolism. 2008 Sep;57(9):1299-306.PMID: 18702958 [PubMed - indexed for MEDLINE]Related articles

Primary prevention of cardiovascular disease and type 2 diabetes in patients at metabolic risk: an endocrine society clinical practice guideline.

Rosenzweig JL, Ferrannini E, Grundy SM, Haffner SM, Heine RJ, Horton ES, Kawamori R; Endocrine Society.

J Clin Endocrinol Metab. 2008 Oct;93(10):3671-89. Epub 2008 Jul 29.PMID: 18664543 [PubMed - indexed for MEDLINE]Related articlesFree article

Dose-dependent requirement of patched homologue 1 in mouse pancreatic beta cell mass.

Nakayama S, Arakawa M, Uchida T, Ogihara T, Kanno R, Ikeda F, Azuma K, Hirose T, Kawamori R, Fujitani Y, Watada H.

Diabetologia. 2008 Oct;51(10):1883-92. Epub 2008 Jul 25.PMID: 18654758 [PubMed - indexed for MEDLINE]Related articles

Stratified analyses for selecting appropriate target patients with diabetic peripheral neuropathy for long-term treatment with an aldose reductase inhibitor, epalrestat.

Hotta N, Kawamori R, Atsumi Y, Baba M, Kishikawa H, Nakamura J, Oikawa S, Yamada N, Yasuda H, Shigeta Y; ADCT Study Group.

Diabet Med. 2008 Jul;25(7):818-25.PMID: 18644069 [PubMed - indexed for MEDLINE]Related articlesFree article

Microalbuminuria reduction with telmisartan in normotensive and hypertensive Japanese patients with type 2 diabetes: a post-hoc analysis of The Incipient to Overt: Angiotensin II Blocker, Telmisartan, Investigation on Type 2 Diabetic Nephropathy (INNOVATION) study.

Makino H, Haneda M, Babazono T, Moriya T, Ito S, Iwamoto Y, Kawamori R, Takeuchi M, Katayama S; INNOVATION Study Group.

Hypertens Res. 2008 Apr;31(4):657-64.PMID: 18633177 [PubMed - indexed for MEDLINE]Related articles

Efficacy and safety of modified Yale insulin infusion protocol in Japanese diabetic patients after open-heart surgery.

Tamaki M, Shimizu T, Kanazawa A, Tamura Y, Hanzawa A, Ebato C, Itou C, Yasunari E, Sanke H, Abe H, Kawai J, Okayama K, Matsumoto K, Komiya K, Kawaguchi M, Inagaki N, Watanabe T, Kanazawa Y, Hirose T, Kawamori R, Watada H.

Diabetes Res Clin Pract. 2008 Sep;81(3):296-302. Epub 2008 Jun 16.PMID: 18556085 [PubMed - indexed for MEDLINE]Related articles

Combined expression of transcription factors induces AR42J-B13 cells to differentiate into insulin-producing cells.

Ogihara T, Fujitani Y, Uchida T, Kanno R, Choi JB, Hirose T, Kawamori R, Watada H.

Endocr J. 2008 Aug;55(4):691-8. Epub 2008 May 28.PMID: 18506085 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance.

Kumashiro N, Tamura Y, Uchida T, Ogihara T, Fujitani Y, Hirose T, Mochizuki H, Kawamori R, Watada H.

Diabetes. 2008 Aug;57(8):2083-91. Epub 2008 May 16.PMID: 18487450 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of changes in basal/total daily insulin ratio in type 2 diabetes patients on intensive insulin therapy including insulin glargine (JUN-LAN Study 6).

Tamaki M, Shimizu T, Kanazawa A, Fujitani Y, Watada H, Kawamori R, Hirose T.

Diabetes Res Clin Pract. 2008 Aug;81(2):e1-3. Epub 2008 May 16.PMID: 18486257 [PubMed - indexed for MEDLINE]Related articles

Diabetic retinopathy is associated with pulse wave velocity, not with the augmentation index of pulse waveform.

Ogawa O, Hiraoka K, Watanabe T, Kinoshita J, Kawasumi M, Yoshii H, Kawamori R.

Cardiovasc Diabetol. 2008 Apr 25;7:11.PMID: 18439284 [PubMed - indexed for MEDLINE]Related articlesFree article

Repetitive postprandial hypertriglyceridemia induces monocyte adhesion to aortic endothelial cells in Goto-Kakizaki rats.

Motojima K, Azuma K, Kitahara Y, Miura K, Mita T, Hirose T, Fujitani Y, Kawamori R, Watada H.

Endocr J. 2008 May;55(2):373-9. Epub 2008 Apr 1.PMID: 18379124 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of effects of olmesartan and telmisartan on blood pressure and metabolic parameters in Japanese early-stage type-2 diabetics with hypertension.

Nakayama S, Watada H, Mita T, Ikeda F, Shimizu T, Uchino H, Fujitani Y, Hirose T, Kawamori R.

Hypertens Res. 2008 Jan;31(1):7-13.PMID: 18360012 [PubMed - indexed for MEDLINE]Related articles

Insulin exocytosis in Goto-Kakizaki rat beta-cells subjected to long-term glinide or sulfonylurea treatment.

Kawai J, Ohara-Imaizumi M, Nakamichi Y, Okamura T, Akimoto Y, Matsushima S, Aoyagi K, Kawakami H, Watanabe T, Watada H, Kawamori R, Nagamatsu S.

Biochem J. 2008 May 15;412(1):93-101.PMID: 18254725 [PubMed - indexed for MEDLINE]Related articlesFree article