PubMed

Effects of Coffee on Inflammatory Cytokine Gene Expression in Mice Fed High-Fat Diets.

Fukushima Y, Kasuga M, Nakao K, Shimomura I, Matsuzawa Y.

J Agric Food Chem. 2009 Nov 9. [Epub ahead of print]PMID: 19899759 [PubMed - as supplied by publisher]Related articles

Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance.

Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, Urano T, Zhu HJ, Tsukano H, Tazume H, Kaikita K, Miyashita K, Iwawaki T, Shimabukuro M, Sakaguchi K, Ito T, Nakagata N, Yamada T, Katagiri H, Kasuga M, Ando Y, Ogawa H, Mochizuki N, Itoh H, Suda T, Oike Y.

Cell Metab. 2009 Sep;10(3):178-88.PMID: 19723494 [PubMed - in process]Related articles

Deterioration of glycaemic control associated with anti-insulin antibodies likely induced by health supplements.

Hirota Y, Ogawa W, Murawaki A, Nishiumi T, Komada H, Miyake K, Sakaguchi K, Kasuga M.

Diabet Med. 2009 Sep;26(9):948-51. No abstract available. PMID: 19719720 [PubMed - in process]Related articles

Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation.

Okada Y, Sakaue H, Nagare T, Kasuga M.

Kobe J Med Sci. 2009 Mar 10;54(5):E241-9.PMID: 19628964 [PubMed - indexed for MEDLINE]Related articlesFree article

[Diabetes susceptibility genes]

Kasuga M.

Nippon Rinsho. 2009 Jun;67(6):1090-4. Japanese. PMID: 19507498 [PubMed - indexed for MEDLINE]Related articles

PDK1 coordinates survival pathways and beta-adrenergic response in the heart.

Ito K, Akazawa H, Tamagawa M, Furukawa K, Ogawa W, Yasuda N, Kudo Y, Liao CH, Yamamoto R, Sato T, Molkentin JD, Kasuga M, Noda T, Nakaya H, Komuro I.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8689-94. Epub 2009 May 8.PMID: 19429709 [PubMed - indexed for MEDLINE]Related articlesFree article

A case of hypothalamic panhypopituitarism with empty sella syndrome: case report and review of the literature.

Komada H, Yamamoto M, Okubo S, Nagai K, Iida K, Nakamura T, Hirota Y, Sakaguchi K, Kasuga M, Takahashi Y.

Endocr J. 2009 Aug;56(4):585-9. Epub 2009 Apr 7. Review.PMID: 19352054 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased ribosomal biogenesis induces pancreatic beta cell failure in mice model of type 2 diabetes.

Asahara S, Matsuda T, Kido Y, Kasuga M.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):367-71.PMID: 19309774 [PubMed - indexed for MEDLINE]Related articles

Muscle-specific overexpression of heparin-binding epidermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity.

Fukatsu Y, Noguchi T, Hosooka T, Ogura T, Kotani K, Abe T, Shibakusa T, Inoue K, Sakai M, Tobimatsu K, Inagaki K, Yoshioka T, Matsuo M, Nakae J, Matsuki Y, Hiramatsu R, Kaku K, Okamura H, Fushiki T, Kasuga M.

Endocrinology. 2009 Jun;150(6):2683-91. Epub 2009 Mar 5.PMID: 19264873 [PubMed - indexed for MEDLINE]Related articles

Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association.

Miyake K, Yang W, Hara K, Yasuda K, Horikawa Y, Osawa H, Furuta H, Ng MC, Hirota Y, Mori H, Ido K, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Wang HY, Tanahashi T, Nakamura N, Takeda J, Maeda E, Yamamoto K, Tokunaga K, Ma RC, So WY, Chan JC, Kamatani N, Makino H, Nanjo K, Kadowaki T, Kasuga M.

J Hum Genet. 2009 Apr;54(4):236-41. Epub 2009 Feb 27.PMID: 19247372 [PubMed - in process]Related articles

Pancreatic beta cell mass preserved in heterozygous PDK1 knockout mice.

Takeda A, Kido Y, Hashimoto N, Noda T, Kasuga M.

Kobe J Med Sci. 2008 Sep 5;54(3):E183-90.PMID: 19246967 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and characterization of an alternative promoter of the human PGC-1alpha gene.

Yoshioka T, Inagaki K, Noguchi T, Sakai M, Ogawa W, Hosooka T, Iguchi H, Watanabe E, Matsuki Y, Hiramatsu R, Kasuga M.

Biochem Biophys Res Commun. 2009 Apr 17;381(4):537-43. Epub 2009 Feb 20.PMID: 19233136 [PubMed - indexed for MEDLINE]Related articles

[Obesity and insulin resistance]

Tamori Y, Kasuga M.

Nippon Rinsho. 2009 Feb;67(2):236-44. Review. Japanese. PMID: 19202894 [PubMed - indexed for MEDLINE]Related articles

Phase I and pharmacokinetic study of tegafur-uracil/leucovorin combined with 5-fluorouracil/leucovorin and irinotecan in patients with advanced colorectal cancer.

Chayahara N, Tamura T, Yamamori M, Kadowaki Y, Okuno T, Miki I, Tsuda M, Nishisaki H, Maeda T, Inoue Y, Okumura K, Azuma T, Kasuga M, Sakaeda T, Hirai M.

Am J Clin Oncol. 2009 Feb;32(1):56-60.PMID: 19194126 [PubMed - indexed for MEDLINE]Related articles

Two related cases of type A insulin resistance with compound heterozygous mutations of the insulin receptor gene.

Ogawa W, Iwamoto K, Mori H, Hashiramoto M, Miyake K, Sakaguchi K, Kasuga M.

Diabetes Res Clin Pract. 2009 Mar;83(3):e75-7. Epub 2009 Jan 9.PMID: 19135752 [PubMed - indexed for MEDLINE]Related articles

The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells.

Park SG, Schulze-Luehrman J, Hayden MS, Hashimoto N, Ogawa W, Kasuga M, Ghosh S.

Nat Immunol. 2009 Feb;10(2):158-66. Epub 2009 Jan 4.PMID: 19122654 [PubMed - indexed for MEDLINE]Related articlesFree article

Skp2 promotes adipocyte differentiation via a p27Kip1-independent mechanism in primary mouse embryonic fibroblasts.

Okada M, Sakai T, Nakamura T, Tamamori-Adachi M, Kitajima S, Matsuki Y, Watanabe E, Hiramatsu R, Sakaue H, Kasuga M.

Biochem Biophys Res Commun. 2009 Feb 6;379(2):249-54. Epub 2008 Dec 25.PMID: 19109928 [PubMed - indexed for MEDLINE]Related articles

The Krüppel-like factor KLF15 inhibits transcription of the adrenomedullin gene in adipocytes.

Nagare T, Sakaue H, Takashima M, Takahashi K, Gomi H, Matsuki Y, Watanabe E, Hiramatsu R, Ogawa W, Kasuga M.

Biochem Biophys Res Commun. 2009 Jan 30;379(1):98-103. Epub 2008 Dec 16.PMID: 19094967 [PubMed - indexed for MEDLINE]Related articles

Role of the E3 ubiquitin ligase gene related to anergy in lymphocytes in glucose and lipid metabolism in the liver.

Nakamichi S, Senga Y, Inoue H, Emi A, Matsuki Y, Watanabe E, Hiramatsu R, Ogawa W, Kasuga M.

J Mol Endocrinol. 2009 Feb;42(2):161-9. Epub 2008 Dec 5.PMID: 19060180 [PubMed - indexed for MEDLINE]Related articles

Cell signaling. Fat stress and liver resistance.

Ogawa W, Kasuga M.

Science. 2008 Dec 5;322(5907):1483-4. No abstract available. PMID: 19056968 [PubMed - indexed for MEDLINE]Related articles

Overexpression of the transcriptional coregulator Cited2 protects against glucocorticoid-induced atrophy of C2C12 myotubes.

Tobimatsu K, Noguchi T, Hosooka T, Sakai M, Inagaki K, Matsuki Y, Hiramatsu R, Kasuga M.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):399-403. Epub 2008 Nov 24.PMID: 19032942 [PubMed - indexed for MEDLINE]Related articles

Analysis of factors affecting increase in bone mineral density at lumbar spine by bisphosphonate treatment in postmenopausal osteoporosis.

Kaji H, Hisa I, Inoue Y, Naito J, Sugimoto T, Kasuga M.

J Bone Miner Metab. 2009;27(1):76-82. Epub 2008 Nov 19.PMID: 19018454 [PubMed - indexed for MEDLINE]Related articles

Sequencing and analysis of approximately 40,000 soybean cDNA clones from a full-length-enriched cDNA library.

Umezawa T, Sakurai T, Totoki Y, Toyoda A, Seki M, Ishiwata A, Akiyama K, Kurotani A, Yoshida T, Mochida K, Kasuga M, Todaka D, Maruyama K, Nakashima K, Enju A, Mizukado S, Ahmed S, Yoshiwara K, Harada K, Tsubokura Y, Hayashi M, Sato S, Anai T, Ishimoto M, Funatsuki H, Teraishi M, Osaki M, Shinano T, Akashi R, Sakaki Y, Yamaguchi-Shinozaki K, Shinozaki K.

DNA Res. 2008 Dec;15(6):333-46. Epub 2008 Oct 16.PMID: 18927222 [PubMed - indexed for MEDLINE]Related articlesFree article

Regional differences in temperature sensation and thermal comfort in humans.

Nakamura M, Yoda T, Crawshaw LI, Yasuhara S, Saito Y, Kasuga M, Nagashima K, Kanosue K.

J Appl Physiol. 2008 Dec;105(6):1897-906. Epub 2008 Oct 9.PMID: 18845785 [PubMed - indexed for MEDLINE]Related articles

Reduced insulin signaling and endoplasmic reticulum stress act synergistically to deteriorate pancreatic beta cell function.

Matsuda T, Kido Y, Uchida T, Kasuga M.

Kobe J Med Sci. 2008 Jul 18;54(2):E114-21.PMID: 18772613 [PubMed - indexed for MEDLINE]Related articlesFree article

Taurine administration after appearance of proteinuria retards progression of diabetic nephropathy in rats.

Higo S, Miyata S, Jiang QY, Kitazawa R, Kitazawa S, Kasuga M.

Kobe J Med Sci. 2008 May 23;54(1):E35-45.PMID: 18772607 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-induced GLUT4 movements in C2C12 myoblasts: evidence against a role of conventional kinesin motor proteins.

Takazawa K, Noguchi T, Hosooka T, Yoshioka T, Tobimatsu K, Kasuga M.

Kobe J Med Sci. 2008 May 23;54(1):E14-22.PMID: 18772605 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of serum MCP-1 concentration and MCP-1 polymorphism with insulin resistance in Japanese individuals with obese type 2 diabetes.

Kouyama K, Miyake K, Zenibayashi M, Hirota Y, Teranishi T, Tamori Y, Kanda H, Sakaguchi K, Ohara T, Kasuga M.

Kobe J Med Sci. 2008 Feb 8;53(6):345-54.PMID: 18762729 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylglyoxal induces prostaglandin E2 production in rat mesangial cells.

Uriuhara A, Miyata S, Liu BF, Miyazaki H, Kusunoki H, Kojima H, Yamashita Y, Suzuki K, Inaba K, Kasuga M.

Kobe J Med Sci. 2008 Feb 8;53(6):305-15.PMID: 18762725 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, Mori H, Jonsson A, Sato Y, Yamagata K, Hinokio Y, Wang HY, Tanahashi T, Nakamura N, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Takeda J, Maeda E, Shin HD, Cho YM, Park KS, Lee HK, Ng MC, Ma RC, So WY, Chan JC, Lyssenko V, Tuomi T, Nilsson P, Groop L, Kamatani N, Sekine A, Nakamura Y, Yamamoto K, Yoshida T, Tokunaga K, Itakura M, Makino H, Nanjo K, Kadowaki T, Kasuga M.

Nat Genet. 2008 Sep;40(9):1092-7.PMID: 18711367 [PubMed - indexed for MEDLINE]Related articles

FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.

Nishino N, Tamori Y, Tateya S, Kawaguchi T, Shibakusa T, Mizunoya W, Inoue K, Kitazawa R, Kitazawa S, Matsuki Y, Hiramatsu R, Masubuchi S, Omachi A, Kimura K, Saito M, Amo T, Ohta S, Yamaguchi T, Osumi T, Cheng J, Fujimoto T, Nakao H, Nakao K, Aiba A, Okamura H, Fushiki T, Kasuga M.

J Clin Invest. 2008 Aug;118(8):2808-21.PMID: 18654663 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association of LRP5 and LRP6 polymorphisms with type 2 diabetes mellitus in the Japanese population.

Zenibayashi M, Miyake K, Horikawa Y, Hirota Y, Teranishi T, Kouyama K, Sakaguchi K, Takeda J, Kasuga M.

Endocr J. 2008 Aug;55(4):699-707. Epub 2008 May 21.PMID: 18493104 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan.

Horikawa Y, Miyake K, Yasuda K, Enya M, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Kasuga M.

J Clin Endocrinol Metab. 2008 Aug;93(8):3136-41. Epub 2008 May 13.PMID: 18477659 [PubMed - indexed for MEDLINE]Related articlesFree article

PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression.

Nakamura K, Sakaue H, Nishizawa A, Matsuki Y, Gomi H, Watanabe E, Hiramatsua R, Tamamori-Adachi M, Kitajima S, Noda T, Ogawa W, Kasuga M.

J Biol Chem. 2008 Jun 20;283(25):17702-11. Epub 2008 Apr 22.PMID: 18430722 [PubMed - indexed for MEDLINE]Related articlesFree article

VEGF T-1498C polymorphism, a predictive marker of differentiation of colorectal adenocarcinomas in Japanese.

Yamamori M, Taniguchi M, Maeda S, Nakamura T, Okamura N, Kuwahara A, Iwaki K, Tamura T, Aoyama N, Markova S, Kasuga M, Okumura K, Sakaeda T.

Int J Med Sci. 2008 Apr 8;5(2):80-6.PMID: 18414651 [PubMed - indexed for MEDLINE]Related articlesFree article

Biphasic response of pancreatic beta-cell mass to ablation of tuberous sclerosis complex 2 in mice.

Shigeyama Y, Kobayashi T, Kido Y, Hashimoto N, Asahara S, Matsuda T, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Uchida T, Inoue M, Hino O, Kasuga M, Noda T.

Mol Cell Biol. 2008 May;28(9):2971-9. Epub 2008 Mar 3.PMID: 18316403 [PubMed - indexed for MEDLINE]Related articlesFree article

Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma.

Satake S, Semba S, Matsuda Y, Usami Y, Chiba H, Sawada N, Kasuga M, Yokozaki H.

Pathol Int. 2008 Mar;58(3):156-63.PMID: 18251778 [PubMed - indexed for MEDLINE]Related articles

Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes.

Takahashi M, Takahashi Y, Takahashi K, Zolotaryov FN, Hong KS, Kitazawa R, Iida K, Okimura Y, Kaji H, Kitazawa S, Kasuga M, Chihara K.

FEBS Lett. 2008 Mar 5;582(5):573-8. Epub 2008 Jan 31.PMID: 18242188 [PubMed - indexed for MEDLINE]Related articles

Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation.

Hosooka T, Noguchi T, Kotani K, Nakamura T, Sakaue H, Inoue H, Ogawa W, Tobimatsu K, Takazawa K, Sakai M, Matsuki Y, Hiramatsu R, Yasuda T, Lazar MA, Yamanashi Y, Kasuga M.

Nat Med. 2008 Feb;14(2):188-93. Epub 2008 Jan 20.PMID: 18204460 [PubMed - indexed for MEDLINE]Related articles

Insulin-stimulated fusion of GLUT4 vesicles to plasma membrane is dependent on wortmannin-sensitive insulin signaling pathway in 3T3-L1 adipocytes.

Kawaguchi T, Tamori Y, Yoshikawa M, Kanda H, Kasuga M.

Kobe J Med Sci. 2008 Oct 30;54(4):E209-16.PMID: 19258741 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of hepatic STAT3 in the regulation of lipid metabolism.

Kinoshita S, Ogawa W, Okamoto Y, Takashima M, Inoue H, Matsuki Y, Watanabe E, Hiramatsu R, Kasuga M.

Kobe J Med Sci. 2008 Oct 30;54(4):E200-8.PMID: 19258740 [PubMed - indexed for MEDLINE]Related articlesFree article

Association study of the effect of WFS1 polymorphisms on risk of type 2 diabetes in Japanese population.

Mita M, Miyake K, Zenibayashi M, Hirota Y, Teranishi T, Kouyama K, Sakaguchi K, Kasuga M.

Kobe J Med Sci. 2008 Oct 30;54(4):E192-9.PMID: 19258739 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects.

Miyake K, Horikawa Y, Hara K, Yasuda K, Osawa H, Furuta H, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Makino H, Nanjo K, Kadowaki T, Kasuga M.

J Hum Genet. 2008;53(2):174-80. Epub 2007 Dec 21.PMID: 18097733 [PubMed - indexed for MEDLINE]Related articles

[Adverse effects of alpha-glucosidase inhibitors]

Sakaguchi K, Kasuga M.

Nippon Rinsho. 2007 Oct 28;65 Suppl 8:183-7. Review. Japanese. No abstract available. PMID: 18074536 [PubMed - indexed for MEDLINE]Related articles

[Disturbances in the mechanism of signal transduction related to insulin at the onset of diabetes mellitus]

Kasuga M.

Nippon Naika Gakkai Zasshi. 2007 Sep 10;96(9):1836-44. Review. Japanese. No abstract available. PMID: 17929420 [PubMed - indexed for MEDLINE]Related articles

Frequency-dependent changes in absolute hearing threshold caused by perception of a previous sound.

Yoshida J, Hasegawa H, Kasuga M.

J Acoust Soc Am. 2007 Sep;122(3):EL62.PMID: 17927309 [PubMed - indexed for MEDLINE]Related articles

Relationship of BRAF mutation, morphology, and apoptosis in early colorectal cancer.

Yoshida S, Ikehara N, Aoyama N, Shirasaka D, Sakashita M, Semba S, Hasuo T, Miki I, Morita Y, Tamura T, Azuma T, Yokozaki H, Kasuga M.

Int J Colorectal Dis. 2008 Jan;23(1):7-13. Epub 2007 Oct 9.PMID: 17924122 [PubMed - indexed for MEDLINE]Related articles

Effects of pioglitazone and metformin on intracellular lipid content in liver and skeletal muscle of individuals with type 2 diabetes mellitus.

Teranishi T, Ohara T, Maeda K, Zenibayashi M, Kouyama K, Hirota Y, Kawamitsu H, Fujii M, Sugimura K, Kasuga M.

Metabolism. 2007 Oct;56(10):1418-24.PMID: 17884455 [PubMed - indexed for MEDLINE]Related articles

Role of metallothionein in Helicobacter pylori-positive gastric mucosa with or without early gastric cancer and the effect on its expression after eradication therapy.

Mitani T, Shirasaka D, Aoyama N, Miki I, Morita Y, Ikehara N, Matsumoto Y, Okuno T, Toyoda M, Miyachi H, Yoshida S, Chayahara N, Hori J, Tamura T, Azuma T, Kasuga M.

J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e334-9. Epub 2007 Aug 27.PMID: 17725597 [PubMed - indexed for MEDLINE]Related articles

Frequency of the G/G genotype of resistin single nucleotide polymorphism at -420 appears to be increased in younger-onset type 2 diabetes.

Ochi M, Osawa H, Hirota Y, Hara K, Tabara Y, Tokuyama Y, Shimizu I, Kanatsuka A, Fujii Y, Ohashi J, Miki T, Nakamura N, Kadowaki T, Itakura M, Kasuga M, Makino H.

Diabetes. 2007 Nov;56(11):2834-8. Epub 2007 Aug 13.PMID: 17698599 [PubMed - indexed for MEDLINE]Related articlesFree article