PubMed

The risk of tendon xanthomas in familial hypercholesterolaemia is influenced by variation in genes of the reverse cholesterol transport pathway and the low-density lipoprotein oxidation pathway.

Oosterveer DM, Versmissen J, Yazdanpanah M, Defesche JC, Kastelein JJ, Sijbrands EJ.

Eur Heart J. 2009 Dec 16. [Epub ahead of print]PMID: 20019024 [PubMed - as supplied by publisher]

Effect of apolipoprotein-B synthesis inhibition on liver triglyceride content in patients with familial hypercholesterolemia.

Visser ME, Akdim F, Tribble DL, Nederveen AJ, Kwoh TJ, Kastelein JJ, Trip MD, Stroes ES.

J Lipid Res. . [Epub ahead of print]PMID: 20008831 [PubMed - as supplied by publisher]Related articlesFree article

The genetics of high-density lipoprotein metabolism: clinical relevance for therapeutic approaches.

Strang AC, Hovingh GK, Stroes ES, Kastelein JJ.

Am J Cardiol. 2009 Nov 16;104(10 Suppl):22E-31E.PMID: 19895941 [PubMed - in process]Related articles

Physical inactivity, abdominal obesity and risk of coronary heart disease in apparently healthy men and women.

Arsenault BJ, Rana JS, Lemieux I, Després JP, Kastelein JJ, Boekholdt SM, Wareham NJ, Khaw KT.

Int J Obes (Lond). 2009 Nov 17. [Epub ahead of print]PMID: 19918249 [PubMed - as supplied by publisher]Related articles

Dalcetrapib: no off-target toxicity on blood pressure or on genes related to the renin-angiotensin-aldosterone system in rats.

Stroes ES, Kastelein JJ, Bénardeau A, Kuhlmann O, Blum D, Campos LA, Clerc RG, Niesor EJ.

Br J Pharmacol. 2009 Dec;158(7):1763-70. Epub .PMID: 19917065 [PubMed - in process]Related articles

Statin therapy with ezetimibe or niacin in high-risk patients.

Kastelein JJ, Bots ML.

N Engl J Med. 2009 Nov 26;361(22):2180-3. Epub 2009 Nov 15. No abstract available. PMID: 19915218 [PubMed - indexed for MEDLINE]Related articles

Heterozygous familial hypercholesterolaemia in childhood: Cardiovascular risk prevention.

van der Graaf A, Kastelein JJ, Wiegman A.

J Inherit Metab Dis. 2009 Oct 31. [Epub ahead of print]PMID: 19898954 [PubMed - as supplied by publisher]Related articles

Baseline cholesterol absorption and the response to ezetimibe/simvastatin therapy; a post-hoc analysis of the ENHANCE trial.

Jakulj L, Vissers MN, Groen AK, Hutten BA, Lutjohann D, Veltri EP, Kastelein JJ.

J Lipid Res. 2009 Oct 14. [Epub ahead of print]PMID: 19828909 [PubMed - as supplied by publisher]Related articlesFree article

Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in The Netherlands.

Pijlman AH, Huijgen R, Verhagen SN, Imholz BP, Liem AH, Kastelein JJ, Abbink EJ, Stalenhoef AF, Visseren FL.

Atherosclerosis. 2009 Sep 15. [Epub ahead of print]PMID: 19818960 [PubMed - as supplied by publisher]Related articles

In vivo quantification of carotid artery wall dimensions: 3.0-Tesla MRI versus B-mode ultrasound imaging.

Duivenvoorden R, de Groot E, Elsen BM, Laméris JS, van der Geest RJ, Stroes ES, Kastelein JJ, Nederveen AJ.

Circ Cardiovasc Imaging. 2009 May;2(3):235-42. Epub 2009 Mar 19.PMID: 19808598 [PubMed - indexed for MEDLINE]Related articles

Is insulin the preferred compound in lowering glucose levels in patients after a myocardial infarction?

Rensing KL, Kastelein JJ, Twickler M.

Arch Intern Med. 2009 Sep 28;169(17):1636-7; author reply 1637-8. No abstract available. PMID: 19786687 [PubMed - indexed for MEDLINE]Related articles

Paraoxonase variants relate to 10-year risk in coronary artery disease: impact of a high-density lipoprotein-bound antioxidant in secondary prevention.

Regieli JJ, Jukema JW, Doevendans PA, Zwinderman AH, Kastelein JJ, Grobbee DE, van der Graaf Y.

J Am Coll Cardiol. 2009 Sep 29;54(14):1238-45.PMID: 19778663 [PubMed - indexed for MEDLINE]Related articles

Lipid measures and cardiovascular disease prediction.

van Wijk DF, Stroes ES, Kastelein JJ.

Dis Markers. 2009;26(5-6):209-16. Review.PMID: 19773610 [PubMed - indexed for MEDLINE]Related articles

Physical activity, the Framingham risk score and risk of coronary heart disease in men and women of the EPIC-Norfolk study.

Arsenault BJ, Rana JS, Lemieux I, Després JP, Wareham NJ, Kastelein JJ, Boekholdt SM, Khaw KT.

Atherosclerosis. 2009 Aug 31. [Epub ahead of print]PMID: 19772963 [PubMed - as supplied by publisher]Related articles

Prolactin fragmentation by trophoblastic matrix metalloproteinases as a possible contributor to peripartum cardiomyopathy and pre-eclampsia.

Reuwer AQ, Reuwer PJ, van der Post JA, Cramer MJ, Kastelein JJ, Twickler MT.

Med Hypotheses. 2009 Sep 10. [Epub ahead of print]PMID: 19748190 [PubMed - as supplied by publisher]Related articles

Pregnancy in women suffering from familial hypercholesterolemia: a harmful period for both mother and newborn?

Avis HJ, Hutten BA, Twickler MT, Kastelein JJ, van der Post JA, Stalenhoef AF, Vissers MN.

Curr Opin Lipidol. 2009 Dec;20(6):484-90.PMID: 19741526 [PubMed - in process]Related articles

Hormones and cardiovascular disease: a shift in paradigm with clinical consequences?

van Zaane B, Reuwer AQ, Büller HR, Kastelein JJ, Gerdes VE, Twickler MT.

Semin Thromb Hemost. 2009 Jul;35(5):478-87. Epub 2009 Sep 8. Review.PMID: 19739038 [PubMed - in process]Related articles

Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study.

Birjmohun RS, Vergeer M, Stroes ES, Sandhu MS, Ricketts SL, Tanck MW, Wareham NJ, Jukema JW, Kastelein JJ, Khaw KT, Boekholdt SM.

PLoS One. 2009 Aug 27;4(8):e6809.PMID: 19710913 [PubMed - in process]Related articlesFree article

Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women - a prospective case-control analysis nested in the EPIC-Norfolk population study.

Holleboom AG, Kuivenhoven JA, Vergeer M, Hovingh GK, van Miert JN, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM.

J Lipid Res. 2009 Aug 11. [Epub ahead of print]PMID: 19671930 [PubMed - as supplied by publisher]Related articlesFree article

Nevirapine increases high-density lipoprotein cholesterol concentration by stimulation of apolipoprotein A-I production.

Franssen R, Sankatsing RR, Hassink E, Hutten B, Ackermans MT, Brinkman K, Oesterholt R, Arenas-Pinto A, Storfer SP, Kastelein JJ, Sauerwein HP, Reiss P, Stroes ES.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1336-41. Epub 2009 Aug 10.PMID: 19667106 [PubMed - indexed for MEDLINE]Related articles

Plasma triglycerides and cardiovascular events in the Treating to New Targets and Incremental Decrease in End-Points through Aggressive Lipid Lowering trials of statins in patients with coronary artery disease.

Faergeman O, Holme I, Fayyad R, Bhatia S, Grundy SM, Kastelein JJ, LaRosa JC, Larsen ML, Lindahl C, Olsson AG, Tikkanen MJ, Waters DD, Pedersen TR; Steering Committees of IDEAL and TNT Trials.

Am J Cardiol. 2009 Aug 15;104(4):459-63. Epub 2009 Jun 24.PMID: 19660594 [PubMed - indexed for MEDLINE]Related articles

Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia.

Harchaoui KE, Franssen R, Hovingh GK, Bisoendial RJ, Stellaard F, Kuipers F, Kastelein JJ, Kuivenhoven JA, Stroes ES, Groen AK.

Atherosclerosis. 2009 Dec;207(2):614-6. Epub 2009 Jun 18.PMID: 19616211 [PubMed - in process]Related articles

Inflammatory biomarkers and the prediction of coronary events among people at intermediate risk: the EPIC-Norfolk prospective population study.

Rana JS, Cote M, Després JP, Sandhu MS, Talmud PJ, Ninio E, Wareham NJ, Kastelein JJ, Zwinderman AH, Khaw KT, Boekholdt SM.

Heart. 2009 Oct;95(20):1682-7. Epub 2009 Jul 8.PMID: 19587389 [PubMed - indexed for MEDLINE]Related articles

Air pollution as noxious environmental factor in the development of cardiovascular disease.

Hassing HC, Twickler TB, Kastelein JJ, Cramer MJ, Cassee FR.

Neth J Med. 2009 Apr;67(4):116-21. Review.PMID: 19581654 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety and tolerability of dalcetrapib.

Stein EA, Stroes ES, Steiner G, Buckley BM, Capponi AM, Burgess T, Niesor EJ, Kallend D, Kastelein JJ.

Am J Cardiol. 2009 Jul 1;104(1):82-91.PMID: 19576325 [PubMed - indexed for MEDLINE]Related articles

Comparison of in vivo carotid 3.0-T magnetic resonance to B-mode ultrasound imaging and histology in a porcine model.

Duivenvoorden R, de Groot E, Afzali H, Vanbavel ET, de Boer OJ, Laméris JS, Fayad ZA, Stroes ES, Kastelein JJ, Nederveen AJ.

JACC Cardiovasc Imaging. 2009 Jun;2(6):744-50.PMID: 19520346 [PubMed - indexed for MEDLINE]Related articles

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells.

Mingozzi F, Meulenberg JJ, Hui DJ, Basner-Tschakarjan E, Hasbrouck NC, Edmonson SA, Hutnick NA, Betts MR, Kastelein JJ, Stroes ES, High KA.

Blood. 2009 Sep 3;114(10):2077-86. Epub 2009 Jun 8.PMID: 19506302 [PubMed - indexed for MEDLINE]Related articles

Prolactin does not affect human platelet aggregation or secretion.

Reuwer AQ, Nieuwland R, Fernandez I, Goffin V, van Tiel CM, Schaap MC, Berckmans RJ, Kastelein JJ, Twickler MT.

Thromb Haemost. 2009 Jun;101(6):1119-27.PMID: 19492157 [PubMed - in process]Related articles

C-reactive protein elicits white blood cell activation in humans.

Bisoendial RJ, Birjmohun RS, Akdim F, van 't Veer C, Spek CA, Hartman D, de Groot ER, Bankaitis-Davis DM, Kastelein JJ, Stroes ES.

Am J Med. 2009 Jun;122(6):582.e1-9.PMID: 19486722 [PubMed - indexed for MEDLINE]Related articles

Comparative effect of atorvastatin (80 mg) versus simvastatin (20 to 40 mg) in preventing hospitalizations for heart failure in patients with previous myocardial infarction.

Strandberg TE, Holme I, Faergeman O, Kastelein JJ, Lindahl C, Larsen ML, Olsson AG, Pedersen TR, Tikkanen MJ; IDEAL Study Group.

Am J Cardiol. 2009 May 15;103(10):1381-5. Epub 2009 Mar 25.PMID: 19427432 [PubMed - indexed for MEDLINE]Related articles

Metabolic dyslipidemia and risk of future coronary heart disease in apparently healthy men and women: The EPIC-Norfolk prospective population study.

Rana JS, Visser ME, Arsenault BJ, Després JP, Stroes ES, Kastelein JJ, Wareham NJ, Boekholdt SM, Khaw KT.

Int J Cardiol. 2009 Apr 24. [Epub ahead of print]PMID: 19394708 [PubMed - as supplied by publisher]Related articles

5-Lipoxygenase activating protein (ALOX5AP) gene variants associate with the presence of xanthomas in familial hypercholesterolemia.

Oosterveer DM, Versmissen J, Yazdanpanah M, van der Net JB, Defesche JC, Kastelein JJ, Sijbrands EJ.

Atherosclerosis. 2009 Sep;206(1):223-7. Epub 2009 Feb 25.PMID: 19361804 [PubMed - indexed for MEDLINE]Related articles

The use of lipid-lowering drug therapy in children and adolescents.

Avis HJ, Vissers MN, Wijburg FA, Kastelein JJ, Hutten BA.

Curr Opin Investig Drugs. 2009 Mar;10(3):224-31. Review.PMID: 19333879 [PubMed - indexed for MEDLINE]Related articles

A randomized trial of rosuvastatin in the prevention of venous thromboembolism.

Glynn RJ, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Ridker PM.

N Engl J Med. 2009 Apr 30;360(18):1851-61. Epub 2009 Mar 29.PMID: 19329822 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial.

Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Macfadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Trial Study Group.

Lancet. 2009 Apr 4;373(9670):1175-82. Epub 2009 Mar 28.PMID: 19329177 [PubMed - indexed for MEDLINE]Related articles

Congestive heart failure is associated with lipoprotein components in statin-treated patients with coronary heart disease Insights from the Incremental Decrease in End points Through Aggressive Lipid Lowering Trial (IDEAL).

Holme I, Strandberg TE, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Larsen ML, Lindahl C, Pedersen TR; Incremental Decrease in End Points Through Aggressive Lipid Lowering Study Group.

Atherosclerosis. 2009 Aug;205(2):522-7. Epub 2009 Jan 24.PMID: 19327776 [PubMed - indexed for MEDLINE]Related articles

Surrogate markers in clinical trials--challenges and opportunities.

Duivenvoorden R, de Groot E, Stroes ES, Kastelein JJ.

Atherosclerosis. 2009 Sep;206(1):8-16. Epub 2008 Dec 14. Review.PMID: 19327774 [PubMed - indexed for MEDLINE]Related articles

Osteoprotegerin and soluble receptor activator of nuclear factor-kappaB ligand and risk for coronary events: a nested case-control approach in the prospective EPIC-Norfolk population study 1993-2003.

Semb AG, Ueland T, Aukrust P, Wareham NJ, Luben R, Gullestad L, Kastelein JJ, Khaw KT, Boekholdt SM.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):975-80. Epub 2009 Mar 26.PMID: 19325145 [PubMed - indexed for MEDLINE]Related articles

Adherence-adjusted efficacy with intensive versus standard statin therapy in patients with acute myocardial infarction in the IDEAL study.

Holme I, Szarek M, Cater NB, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Larsen ML, Lindahl C, Pedersen TR; Incremental Decrease in End Points Through Aggressive Lipid Lowering Study Group.

Eur J Cardiovasc Prev Rehabil. 2009 Jun;16(3):315-20.PMID: 19322096 [PubMed - indexed for MEDLINE]Related articles

Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase.

Beigneux AP, Franssen R, Bensadoun A, Gin P, Melford K, Peter J, Walzem RL, Weinstein MM, Davies BS, Kuivenhoven JA, Kastelein JJ, Fong LG, Dallinga-Thie GM, Young SG.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):956-62. Epub 2009 Mar 19.PMID: 19304573 [PubMed - indexed for MEDLINE]Related articles

ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial.

Meuwese MC, de Groot E, Duivenvoorden R, Trip MD, Ose L, Maritz FJ, Basart DC, Kastelein JJ, Habib R, Davidson MH, Zwinderman AH, Schwocho LR, Stein EA; CAPTIVATE Investigators.

JAMA. 2009 Mar 18;301(11):1131-9.PMID: 19293413 [PubMed - indexed for MEDLINE]Related articlesFree article

HDL particle size and the risk of coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.

Arsenault BJ, Lemieux I, Després JP, Gagnon P, Wareham NJ, Stroes ES, Kastelein JJ, Khaw KT, Boekholdt SM.

Atherosclerosis. 2009 Sep;206(1):276-81. Epub 2009 Feb 12.PMID: 19268944 [PubMed - indexed for MEDLINE]Related articles

Comparison of efficacy and safety of atorvastatin (80 mg) to simvastatin (20 to 40 mg) in patients aged <65 versus >or=65 years with coronary heart disease (from the Incremental DEcrease through Aggressive Lipid Lowering [IDEAL] study).

Tikkanen MJ, Holme I, Cater NB, Szarek M, Faergeman O, Kastelein JJ, Olsson AG, Larsen ML, Lindahl C, Pedersen TR; Incremental DEcrease through Aggressive Lipid Lowering Investigators.

Am J Cardiol. 2009 Mar 1;103(5):577-82. Epub 2009 Jan 17.PMID: 19231315 [PubMed - indexed for MEDLINE]Related articles

PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.

Regieli JJ, Jukema JW, Doevendans PA, Zwinderman AH, van der Graaf Y, Kastelein JJ, Grobbee DE.

Diabetes Care. 2009 May;32(5):839-44. Epub 2009 Feb 19.PMID: 19228871 [PubMed - indexed for MEDLINE]Related articlesFree article

Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women.

Rana JS, Arsenault BJ, Després JP, Côté M, Talmud PJ, Ninio E, Jukema JW, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM.

Eur Heart J. 2009 Feb 18. [Epub ahead of print]PMID: 19224930 [PubMed - as supplied by publisher]Related articles

Role of plasma adiponectin on the HDL-cholesterol raising effect of atorvastatin in patients with type 2 diabetes.

van Hoek M, van Tol A, van Vark-van der Zee LC, Jansen H, Kastelein JJ, Sijbrands EJ, Dallinga-Thie GM.

Curr Med Res Opin. 2009 Jan;25(1):93-101.PMID: 19210142 [PubMed - indexed for MEDLINE]Related articles

Effects of short-term and long-term danazol treatment on lipoproteins, coagulation, and progression of atherosclerosis: two clinical trials in healthy volunteers and patients with hereditary angioedema.

Birjmohun RS, Kees Hovingh G, Stroes ES, Hofstra JJ, Dallinga-Thie GM, Meijers JC, Kastelein JJ, Levi M.

Clin Ther. 2008 Dec;30(12):2314-23.PMID: 19167590 [PubMed - indexed for MEDLINE]Related articles

Usefulness of genetic polymorphisms and conventional risk factors to predict coronary heart disease in patients with familial hypercholesterolemia.

van der Net JB, Janssens AC, Defesche JC, Kastelein JJ, Sijbrands EJ, Steyerberg EW.

Am J Cardiol. 2009 Feb 1;103(3):375-80. Epub 2008 Nov 21.PMID: 19166692 [PubMed - indexed for MEDLINE]Related articles

Lipoprotein predictors of cardiovascular events in statin-treated patients with coronary heart disease. Insights from the Incremental Decrease In End-points Through Aggressive Lipid-lowering Trial (IDEAL).

Holme I, Cater NB, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Larsen ML, Lindahl C, Pedersen TR; Incremental Decrease in End-Points Through Aggressive Lipid-Lowering (IDEAL) Study Group.

Ann Med. 2008;40(6):456-64.PMID: 19160529 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein particle size and concentration and coronary risk.

El Harchaoui K, Arsenault BJ, Franssen R, Després JP, Hovingh GK, Stroes ES, Otvos JD, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM.

Ann Intern Med. 2009 Jan 20;150(2):84-93.PMID: 19153411 [PubMed - indexed for MEDLINE]Related articlesFree article