PubMed

Association between statin-associated myopathy and skeletal muscle damage.

Mohaupt MG, Karas RH, Babiychuk EB, Sanchez-Freire V, Monastyrskaya K, Iyer L, Hoppeler H, Breil F, Draeger A.

CMAJ. 2009 Jul 7;181(1-2):E11-8.PMID: 19581603 [PubMed - indexed for MEDLINE]Related articlesFree article

Modestly overweight women have vascular endothelial dysfunction.

Patel AR, Hui H, Kuvin JT, Pandian NG, Karas RH.

Clin Cardiol. 2009 May;32(5):269-73.PMID: 19452485 [PubMed - in process]Related articles

Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice.

Park HJ, Zhang Y, Du C, Welzig CM, Madias C, Aronovitz MJ, Georgescu SP, Naggar I, Wang B, Kim YB, Blaustein RO, Karas RH, Liao R, Mathews CE, Galper JB.

Circ Res. 2009 Jul 31;105(3):287-94. Epub 2009 May 7.PMID: 19423844 [PubMed - indexed for MEDLINE]Related articlesFree article

The relationship of statins to rhabdomyolysis, malignancy, and hepatic toxicity: evidence from clinical trials.

Alsheikh-Ali AA, Karas RH.

Curr Atheroscler Rep. 2009 Mar;11(2):100-4. Review.PMID: 19228482 [PubMed - indexed for MEDLINE]Related articles

Carotid artery stiffness, high-density lipoprotein cholesterol and inflammation in men with pre-hypertension.

Heffernan KS, Karas RH, Kuvin JT, Jae SY, Vieira VJ, Fernhall B.

J Hum Hypertens. 2009 Sep;23(9):590-6. Epub 2009 Feb 19.PMID: 19225528 [PubMed - in process]Related articles

Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation.

Donaldson C, Eder S, Baker C, Aronovitz MJ, Weiss AD, Hall-Porter M, Wang F, Ackerman A, Karas RH, Molkentin JD, Patten RD.

Circ Res. 2009 Jan 30;104(2):265-75, 11p following 275. Epub 2008 Dec 12.PMID: 19074476 [PubMed - indexed for MEDLINE]Related articles

Statins, low-density lipoprotein cholesterol, and risk of cancer.

Alsheikh-Ali AA, Trikalinos TA, Kent DM, Karas RH.

J Am Coll Cardiol. 2008 Sep 30;52(14):1141-7.PMID: 18804740 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of the inducible nitric oxide synthase gene by estrogen receptors 1 and 2.

Tsutsumi S, Zhang X, Takata K, Takahashi K, Karas RH, Kurachi H, Mendelsohn ME.

J Endocrinol. 2008 Nov;199(2):267-73. Epub 2008 Aug 27.PMID: 18753331 [PubMed - indexed for MEDLINE]Related articlesFree article

Statins and interstitial lung disease: a systematic review of the literature and of food and drug administration adverse event reports.

Fernández AB, Karas RH, Alsheikh-Ali AA, Thompson PD.

Chest. 2008 Oct;134(4):824-30. Epub 2008 Aug 8. Review.PMID: 18689579 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society.

Utian WH, Archer DF, Bachmann GA, Gallagher C, Grodstein F, Heiman JR, Henderson VW, Hodis HN, Karas RH, Lobo RA, Manson JE, Reid RL, Schmidt PJ, Stuenkel CA; North American Menopause Society.

Menopause. 2008 Jul-Aug;15(4 Pt 1):584-602.PMID: 18580541 [PubMed - indexed for MEDLINE]Related articlesFree article

The safety of niacin in the US Food and Drug Administration adverse event reporting database.

Alsheikh-Ali AA, Karas RH.

Am J Cardiol. 2008 Apr 17;101(8A):9B-13B. Review.PMID: 18375244 [PubMed - indexed for MEDLINE]Related articles

Comparison of the safety and efficacy of a combination tablet of niacin extended release and simvastatin vs simvastatin monotherapy in patients with increased non-HDL cholesterol (from the SEACOAST I study).

Ballantyne CM, Davidson MH, McKenney J, Keller LH, Bajorunas DR, Karas RH.

Am J Cardiol. 2008 May 15;101(10):1428-36.PMID: 18471454 [PubMed - indexed for MEDLINE]Related articles

High blood pressure arising from a defect in vascular function.

Michael SK, Surks HK, Wang Y, Zhu Y, Blanton R, Jamnongjit M, Aronovitz M, Baur W, Ohtani K, Wilkerson MK, Bonev AD, Nelson MT, Karas RH, Mendelsohn ME.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6702-7. Epub 2008 Apr 30.PMID: 18448676 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels.

Peter I, Kelley-Hedgepeth A, Fox CS, Cupples LA, Huggins GS, Housman DE, Karas RH, Mendelsohn ME, Levy D, Murabito JM.

J Clin Endocrinol Metab. 2008 Jul;93(7):2779-85. Epub 2008 Apr 29.PMID: 18445666 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term safety and efficacy of a combination of niacin extended release and simvastatin in patients with dyslipidemia: the OCEANS study.

Karas RH, Kashyap ML, Knopp RH, Keller LH, Bajorunas DR, Davidson MH.

Am J Cardiovasc Drugs. 2008;8(2):69-81.PMID: 18422390 [PubMed - indexed for MEDLINE]Related articles

17 Beta-estradiol differentially affects left ventricular and cardiomyocyte hypertrophy following myocardial infarction and pressure overload.

Patten RD, Pourati I, Aronovitz MJ, Alsheikh-Ali A, Eder S, Force T, Mendelsohn ME, Karas RH.

J Card Fail. 2008 Apr;14(3):245-53.PMID: 18381189 [PubMed - indexed for MEDLINE]Related articles

Relative safety of gemfibrozil and fenofibrate in the absence of concomitant cerivastatin use.

Holoshitz N, Alsheikh-Ali AA, Karas RH.

Am J Cardiol. 2008 Jan 1;101(1):95-7. Epub 2007 Nov 26.PMID: 18157972 [PubMed - indexed for MEDLINE]Related articles

Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.

Park HJ, Georgescu SP, Du C, Madias C, Aronovitz MJ, Welzig CM, Wang B, Begley U, Zhang Y, Blaustein RO, Patten RD, Karas RH, Van Tol HH, Osborne TF, Shimano H, Liao R, Link MS, Galper JB.

J Clin Invest. 2008 Jan;118(1):259-71.PMID: 18060044 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence of low high-density lipoprotein cholesterol in patients with documented coronary heart disease or risk equivalent and controlled low-density lipoprotein cholesterol.

Alsheikh-Ali AA, Lin JL, Abourjaily P, Ahearn D, Kuvin JT, Karas RH.

Am J Cardiol. 2007 Nov 15;100(10):1499-501. Epub 2007 Sep 27.PMID: 17996508 [PubMed - indexed for MEDLINE]Related articles

Do the cardiovascular disease risks and benefits of oral versus transdermal estrogen therapy differ between perimenopausal and postmenopausal women?

Clarkson TB, Karas RH.

Menopause. 2007 Nov-Dec;14(6):963-7. No abstract available. PMID: 17909452 [PubMed - indexed for MEDLINE]Related articles

Present-day uses of niacin: effects on lipid and non-lipid parameters.

Sanyal S, Karas RH, Kuvin JT.

Expert Opin Pharmacother. 2007 Aug;8(11):1711-7. Review.PMID: 17685887 [PubMed - indexed for MEDLINE]Related articles

Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.

Alsheikh-Ali AA, Maddukuri PV, Han H, Karas RH.

J Am Coll Cardiol. 2007 Jul 31;50(5):409-18. Epub 2007 Jul 16. Review.PMID: 17662392 [PubMed - indexed for MEDLINE]Related articles

Tendon rupture associated with simvastatin/ezetimibe therapy.

Pullatt RC, Gadarla MR, Karas RH, Alsheikh-Ali AA, Thompson PD.

Am J Cardiol. 2007 Jul 1;100(1):152-3. Epub 2007 May 21.PMID: 17599460 [PubMed - indexed for MEDLINE]Related articles

HRT and the young at heart.

Mendelsohn ME, Karas RH.

N Engl J Med. 2007 Jun 21;356(25):2639-41. No abstract available. PMID: 17582075 [PubMed - indexed for MEDLINE]Related articles

Assessment of peripheral vascular endothelial function in the ambulatory setting.

Kuvin JT, Mammen A, Mooney P, Alsheikh-Ali AA, Karas RH.

Vasc Med. 2007 Feb;12(1):13-6.PMID: 17451088 [PubMed - indexed for MEDLINE]Related articles

Effect of soy protein from differently processed products on cardiovascular disease risk factors and vascular endothelial function in hypercholesterolemic subjects.

Matthan NR, Jalbert SM, Ausman LM, Kuvin JT, Karas RH, Lichtenstein AH.

Am J Clin Nutr. 2007 Apr;85(4):960-6. Erratum in: Am J Clin Nutr. 2007 Aug;86(2):525. PMID: 17413093 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species.

O'Lone R, Knorr K, Jaffe IZ, Schaffer ME, Martini PG, Karas RH, Bienkowska J, Mendelsohn ME, Hansen U.

Mol Endocrinol. 2007 Jun;21(6):1281-96. Epub 2007 Mar 20.PMID: 17374850 [PubMed - indexed for MEDLINE]Related articlesFree article

Age-related changes in echocardiographic measurements: association with variation in the estrogen receptor-alpha gene.

Peter I, Huggins GS, Shearman AM, Pollak A, Schmid CH, Cupples LA, Demissie S, Patten RD, Karas RH, Housman DE, Mendelsohn ME, Vasan RS, Benjamin EJ.

Hypertension. 2007 May;49(5):1000-6. Epub 2007 Mar 19.PMID: 17372038 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system).

Alsheikh-Ali AA, Karas RH.

Am J Cardiol. 2007 Feb 1;99(3):379-81. Epub 2006 Dec 8.PMID: 17261402 [PubMed - indexed for MEDLINE]Related articles

Vascular endothelial dysfunction is associated with reversible myocardial perfusion defects in the absence of obstructive coronary artery disease.

Soman P, Dave DM, Udelson JE, Han H, Ouda HZ, Patel AR, Karas RH, Kuvin JT.

J Nucl Cardiol. 2006 Nov;13(6):756-60.PMID: 17174806 [PubMed - indexed for MEDLINE]Related articles

RACK1 is a BKCa channel binding protein.

Isacson CK, Lu Q, Karas RH, Cox DH.

Am J Physiol Cell Physiol. 2007 Apr;292(4):C1459-66. Epub 2006 Dec 13.PMID: 17166942 [PubMed - indexed for MEDLINE]Related articlesFree article

Low levels of high-density lipoprotein cholesterol are associated with vascular remodeling in cardiac transplant recipients.

Ambrose MS, DeNofrio D, Kuvin JT, Pandian NG, Karas RH, Patel AR.

Transplant Proc. 2006 Nov;38(9):3016-20.PMID: 17112888 [PubMed - indexed for MEDLINE]Related articles

Extent to which accepted serum lipid goals are achieved in a contemporary general medical population with coronary heart disease risk equivalents.

Alsheikh-Ali AA, Lin JL, Abourjaily P, Ahearn D, Kuvin JT, Karas RH.

Am J Cardiol. 2006 Nov 1;98(9):1231-3. Epub 2006 Sep 7.PMID: 17056335 [PubMed - indexed for MEDLINE]Related articles

Evaluation of peripheral vascular endothelial function with a portable ultrasound device.

Alsheikh-Ali AA, Ouda HZ, Pandian N, Karas RH, Kuvin JT.

Echocardiography. 2006 Sep;23(8):623-6.PMID: 16970712 [PubMed - indexed for MEDLINE]Related articles

Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery disease.

Kuvin JT, Dave DM, Sliney KA, Mooney P, Patel AR, Kimmelstiel CD, Karas RH.

Am J Cardiol. 2006 Sep 15;98(6):743-5. Epub 2006 Jul 26.PMID: 16950175 [PubMed - indexed for MEDLINE]Related articles

Hormone replacement therapy and the cardiovascular system lessons learned and unanswered questions.

Ouyang P, Michos ED, Karas RH.

J Am Coll Cardiol. 2006 May 2;47(9):1741-53. Epub 2006 Apr 17. Review.PMID: 16682298 [PubMed - indexed for MEDLINE]Related articles

Estrogen replacement and cardiomyocyte protection.

Patten RD, Karas RH.

Trends Cardiovasc Med. 2006 Apr;16(3):69-75. Review.PMID: 16546686 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein cholesterol-raising strategies.

Kuvin JT, Alsheikh-Ali AA, Karas RH.

J Cardiovasc Pharmacol. 2006 Feb;47(2):196-204. Review.PMID: 16495756 [PubMed - indexed for MEDLINE]Related articles

Association of estrogen receptor beta gene polymorphisms with left ventricular mass and wall thickness in women.

Peter I, Shearman AM, Vasan RS, Zucker DR, Schmid CH, Demissie S, Cupples LA, Kuvin JT, Karas RH, Mendelsohn ME, Housman DE, Benjamin EJ.

Am J Hypertens. 2005 Nov;18(11):1388-95.PMID: 16280269 [PubMed - indexed for MEDLINE]Related articles

Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study.

Peter I, Shearman AM, Zucker DR, Schmid CH, Demissie S, Cupples LA, Larson MG, Vasan RS, D'Agostino RB, Karas RH, Mendelsohn ME, Housman DE, Levy D.

J Hypertens. 2005 Dec;23(12):2193-200.PMID: 16269961 [PubMed - indexed for MEDLINE]Related articles

Gender-based differences in brachial artery flow-mediated vasodilation as an indicator of significant coronary artery disease.

Patel AR, Kuvin JT, Sliney KA, Rand WM, Chiang JC, Udelson JE, Pandian NG, Karas RH.

Am J Cardiol. 2005 Nov 1;96(9):1223-6. Epub 2005 Sep 2.PMID: 16253586 [PubMed - indexed for MEDLINE]Related articles

Peripheral vascular endothelial function correlates with exercise capacity in women.

Patel AR, Kuvin JT, Sliney KA, Rand WM, Pandian NG, Karas RH.

Clin Cardiol. 2005 Sep;28(9):433-6.PMID: 16250267 [PubMed - indexed for MEDLINE]Related articles

Estrogen receptor-alpha variants are associated with lipoprotein size distribution and particle levels in women: the Framingham Heart Study.

Demissie S, Cupples LA, Shearman AM, Gruenthal KM, Peter I, Schmid CH, Karas RH, Housman DE, Mendelsohn ME, Ordovas JM.

Atherosclerosis. 2006 Mar;185(1):210-8. Epub 2005 Jul 7.PMID: 16005459 [PubMed - indexed for MEDLINE]Related articles

Molecular and cellular basis of cardiovascular gender differences.

Mendelsohn ME, Karas RH.

Science. 2005 Jun 10;308(5728):1583-7. Review.PMID: 15947175 [PubMed - indexed for MEDLINE]Related articles

Modulator recognition factor 1, an AT-rich interaction domain family member, is a novel corepressor for estrogen receptor alpha.

Georgescu SP, Li JH, Lu Q, Karas RH, Brown M, Mendelsohn ME.

Mol Endocrinol. 2005 Oct;19(10):2491-501. Epub 2005 Jun 7.PMID: 15941852 [PubMed - indexed for MEDLINE]Related articlesFree article

The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis.

Alsheikh-Ali AA, Ambrose MS, Kuvin JT, Karas RH.

Circulation. 2005 Jun 14;111(23):3051-7. Epub 2005 May 23.PMID: 15911706 [PubMed - indexed for MEDLINE]Related articlesFree article

High-density lipoprotein cholesterol in the cardiovascular equation: does the "good" still count?

Alsheikh-Ali AA, Kuvin JT, Karas RH.

Atherosclerosis. 2005 Jun;180(2):217-23. Review.PMID: 15910846 [PubMed - indexed for MEDLINE]Related articles

p38 mitogen-activated protein kinase activates eNOS in endothelial cells by an estrogen receptor alpha-dependent pathway in response to black tea polyphenols.

Anter E, Chen K, Shapira OM, Karas RH, Keaney JF Jr.

Circ Res. 2005 May 27;96(10):1072-8. Epub 2005 May 5.PMID: 15879307 [PubMed - indexed for MEDLINE]Related articlesFree article

Ventricular assist device therapy normalizes inducible nitric oxide synthase expression and reduces cardiomyocyte apoptosis in the failing human heart.

Patten RD, Denofrio D, El-Zaru M, Kakkar R, Saunders J, Celestin F, Warner K, Rastegar H, Khabbaz KR, Udelson JE, Konstam MA, Karas RH.

J Am Coll Cardiol. 2005 May 3;45(9):1419-24.PMID: 15862412 [PubMed - indexed for MEDLINE]Related articles

Adverse events with concomitant amiodarone and statin therapy.

Alsheikh-Ali AA, Karas RH.

Prev Cardiol. 2005 Spring;8(2):95-7.PMID: 15860984 [PubMed - indexed for MEDLINE]Related articles