PubMed

Disrupted tRNA Gene Diversity and Possible Evolutionary Scenarios.

Sugahara J, Fujishima K, Morita K, Tomita M, Kanai A.

J Mol Evol. 2009 Oct 14. [Epub ahead of print]PMID: 19826747 [PubMed - as supplied by publisher]Related articles

The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair.

Rajagopalan MS, Gupta K, Epperly MW, Franicola D, Zhang X, Wang H, Zhao H, Tyurin VA, Pierce JG, Kagan VE, Wipf P, Kanai AJ, Greenberger JS.

In Vivo. 2009 Sep-Oct;23(5):717-26.PMID: 19779106 [PubMed - indexed for MEDLINE]Related articles

Characterization of RNA aptamers against SRP19 protein having sequences different from SRP RNA.

Haraguchi Y, Kuwasako K, Muto Y, Bessho Y, Nishimoto M, Yokoyama S, Kanai A, Kawai G, Sakamoto T.

Nucleic Acids Symp Ser (Oxf). 2009;(53):265-6.PMID: 19749362 [PubMed - in process]Related articlesFree article

Identification of novel endogenous antisense transcripts by DNA microarray analysis targeting complementary strand of annotated genes.

Numata K, Osada Y, Okada Y, Saito R, Hiraiwa N, Nakaoka H, Yamamoto N, Watanabe K, Okubo K, Kohama C, Kanai A, Abe K, Kiyosawa H.

BMC Genomics. 2009 Aug 22;10:392.PMID: 19698135 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy of a metered-dose 8% lidocaine pump spray for patients with post-herpetic neuralgia.

Kanai A, Kumaki C, Niki Y, Suzuki A, Tazawa T, Okamoto H.

Pain Med. 2009 Jul-Aug;10(5):902-9.PMID: 19682274 [PubMed - indexed for MEDLINE]Related articles

Bifocal contact lenses: History, types, characteristics, and actual state and problems.

Toshida H, Takahashi K, Sado K, Kanai A, Murakami A.

Clin Ophthalmol. 2008 Dec;2(4):869-77.PMID: 19668441 [PubMed - in process]Related articlesFree article

The effectiveness of the Uchida-Kraepelin test for psychological stress: an analysis of plasma and salivary stress substances.

Sugimoto K, Kanai A, Shoji N.

Biopsychosoc Med. 2009 Apr 3;3:5.PMID: 19341484 [PubMed - in process]Related articlesFree article

8% Lidocaine pump spray relieves pain associated with peripheral blood flow disorders.

Suzuki A, Kanai A.

Clin J Pain. 2009 Feb;25(2):107-10.PMID: 19333154 [PubMed - indexed for MEDLINE]Related articles

The analgesic effect of a metered-dose 8% lidocaine pump spray in posttraumatic peripheral neuropathy: a pilot study.

Kanai A, Segawa Y, Okamoto T, Koto M, Okamoto H.

Anesth Analg. 2009 Mar;108(3):987-91.PMID: 19224814 [PubMed - indexed for MEDLINE]Related articles

Treatment of lumbar disk herniation by percutaneous intradiscal high-pressure injection of saline.

Kanai A.

Pain Med. 2009 Jan;10(1):76-84.PMID: 19222772 [PubMed - indexed for MEDLINE]Related articles

Tri-split tRNA is a transfer RNA made from 3 transcripts that provides insight into the evolution of fragmented tRNAs in archaea.

Fujishima K, Sugahara J, Kikuta K, Hirano R, Sato A, Tomita M, Kanai A.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2683-7. Epub 2009 Feb 3.PMID: 19190180 [PubMed - indexed for MEDLINE]Related articlesFree article

Mucosal muscarinic receptors enhance bladder activity in cats with feline interstitial cystitis.

Ikeda Y, Birder L, Buffington C, Roppolo J, Kanai A.

J Urol. 2009 Mar;181(3):1415-22. Epub 2009 Jan 20.PMID: 19157447 [PubMed - indexed for MEDLINE]Related articles

Spontaneous contractions evoke afferent nerve firing in mouse bladders with detrusor overactivity.

McCarthy CJ, Zabbarova IV, Brumovsky PR, Roppolo JR, Gebhart GF, Kanai AJ.

J Urol. 2009 Mar;181(3):1459-66. Epub 2009 Jan 20.PMID: 19157431 [PubMed - indexed for MEDLINE]Related articles

Characterization of a heat-stable enzyme possessing GTP-dependent RNA ligase activity from a hyperthermophilic archaeon, Pyrococcus furiosus.

Kanai A, Sato A, Fukuda Y, Okada K, Matsuda T, Sakamoto T, Muto Y, Yokoyama S, Kawai G, Tomita M.

RNA. 2009 Mar;15(3):420-31. Epub 2009 Jan 20.PMID: 19155324 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted delivery of radioprotective agents to mitochondria.

Zabbarova I, Kanai A.

Mol Interv. 2008 Dec;8(6):294-302. Review.PMID: 19144902 [PubMed - indexed for MEDLINE]Related articles

Comprehensive analysis of archaeal tRNA genes reveals rapid increase of tRNA introns in the order thermoproteales.

Sugahara J, Kikuta K, Fujishima K, Yachie N, Tomita M, Kanai A.

Mol Biol Evol. 2008 Dec;25(12):2709-16. Epub 2008 Oct 1.PMID: 18832079 [PubMed - indexed for MEDLINE]Related articles

Association between future events of brain infarction and soluble levels of intercellular adhesion molecule-1 and C-reactive protein in patients with type 2 diabetes mellitus.

Kanai A, Kawamura T, Umemura T, Nagashima M, Nakamura N, Nakayama M, Sano T, Nakashima E, Hamada Y, Nakamura J, Hotta N.

Diabetes Res Clin Pract. 2008 Nov;82(2):157-64. Epub 2008 Aug 9.PMID: 18692933 [PubMed - indexed for MEDLINE]Related articles

A novel mutation in the cornea-specific keratin 12 gene in Meesmann corneal dystrophy.

Seto T, Fujiki K, Kishishita H, Fujimaki T, Murakami A, Kanai A.

Jpn J Ophthalmol. 2008 May-Jun;52(3):224-6. Epub 2008 Jul 27.PMID: 18661274 [PubMed - indexed for MEDLINE]Related articles

Modulation of bladder myofibroblast activity: implications for bladder function.

Sui GP, Wu C, Roosen A, Ikeda Y, Kanai AJ, Fry CH.

Am J Physiol Renal Physiol. 2008 Sep;295(3):F688-97. Epub 2008 Jul 16.PMID: 18632799 [PubMed - indexed for MEDLINE]Related articlesFree article

Urotheliogenic modulation of intrinsic activity in spinal cord-transected rat bladders: role of mucosal muscarinic receptors.

Ikeda Y, Kanai A.

Am J Physiol Renal Physiol. 2008 Aug;295(2):F454-61. Epub 2008 Jun 11.PMID: 18550643 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of soluble adhesion molecule and C-reactive protein levels with silent brain infarction in patients with and without type 2 diabetes.

Umemura T, Kawamura T, Sakakibara T, Kanai A, Sano T, Hotta N, Sobue G.

Curr Neurovasc Res. 2008 May;5(2):106-11.PMID: 18473826 [PubMed - indexed for MEDLINE]Related articles

Identification of DOCK4 and its splicing variant as PIP3 binding proteins.

Kanai A, Ihara S, Ohdaira T, Shinohara-Kanda A, Iwamatsu A, Fukui Y.

IUBMB Life. 2008 Jul;60(7):467-72.PMID: 18459162 [PubMed - indexed for MEDLINE]Related articles

Glucose control levels, ischaemic brain lesions, and hyperinsulinaemia were associated with cognitive dysfunction in diabetic elderly.

Umegaki H, Kawamura T, Mogi N, Umemura T, Kanai A, Sano T.

Age Ageing. 2008 Jul;37(4):458-61. Epub 2008 Mar 12. No abstract available. PMID: 18339615 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequence evidence in the archaeal genomes that tRNAs emerged through the combination of ancestral genes as 5' and 3' tRNA halves.

Fujishima K, Sugahara J, Tomita M, Kanai A.

PLoS One. 2008 Feb 20;3(2):e1622.PMID: 18286179 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative expression analysis uncovers novel features of endogenous antisense transcription.

Okada Y, Tashiro C, Numata K, Watanabe K, Nakaoka H, Yamamoto N, Okubo K, Ikeda R, Saito R, Kanai A, Abe K, Tomita M, Kiyosawa H.

Hum Mol Genet. 2008 Jun 1;17(11):1631-40. Epub 2008 Feb 18.PMID: 18283053 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of analgesia induced by continuous epidural infusion of plain 1% lidocaine and 1% lidocaine prepared by dilution of 2% lidocaine with the same volume of saline.

Kanai A, Koiso S, Hoka S.

J Clin Anesth. 2007 Nov;19(7):534-8.PMID: 18063209 [PubMed - indexed for MEDLINE]Related articles

Biomechanical investigation of ambulatory training in patients with acetabular dysplasia.

Kanai A, Kiyama T, Genda E, Suzuki Y.

Gait Posture. 2008 Jul;28(1):52-7. Epub 2007 Nov 26.PMID: 18037294 [PubMed - indexed for MEDLINE]Related articles

Permuted tRNA genes expressed via a circular RNA intermediate in Cyanidioschyzon merolae.

Soma A, Onodera A, Sugahara J, Kanai A, Yachie N, Tomita M, Kawamura F, Sekine Y.

Science. 2007 Oct 19;318(5849):450-3. Erratum in: Science. 2007 Dec 21;318(5858):1866. PMID: 17947580 [PubMed - indexed for MEDLINE]Related articlesFree article

Regression of sensory and motor blockade, and analgesia during continuous epidural infusion of ropivacaine and fentanyl in comparison with other local anesthetics.

Kanai A, Osawa S, Suzuki A, Ozawa A, Okamoto H, Hoka S.

Pain Med. 2007 Oct-Nov;8(7):546-53.PMID: 17883739 [PubMed - indexed for MEDLINE]Related articles

Computational analysis of microRNA-mediated antiviral defense in humans.

Watanabe Y, Kishi A, Yachie N, Kanai A, Tomita M.

FEBS Lett. 2007 Oct 2;581(24):4603-10. Epub 2007 Aug 31.PMID: 17825824 [PubMed - indexed for MEDLINE]Related articles

A novel variant lattice corneal dystrophy caused by association of mutation (V625D) in TGFBI gene.

Tian X, Fujiki K, Zhang Y, Murakami A, Li Q, Kanai A, Wang W, Hao Y, Ma Z.

Am J Ophthalmol. 2007 Sep;144(3):473-5.PMID: 17765440 [PubMed - indexed for MEDLINE]Related articles

The function of suburothelial myofibroblasts in the bladder.

Fry CH, Sui GP, Kanai AJ, Wu C.

Neurourol Urodyn. 2007 Oct;26(6 Suppl):914-9. Review.PMID: 17763395 [PubMed - indexed for MEDLINE]Related articles

Computational methods for microRNA target prediction.

Watanabe Y, Tomita M, Kanai A.

Methods Enzymol. 2007;427:65-86. Review.PMID: 17720479 [PubMed - indexed for MEDLINE]Related articles

Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes.

Kochiwa H, Tomita M, Kanai A.

BMC Evol Biol. 2007 Jul 31;7:128.PMID: 17663799 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat.

Birder L, Kullmann FA, Lee H, Barrick S, de Groat W, Kanai A, Caterina M.

J Pharmacol Exp Ther. 2007 Oct;323(1):227-35. Epub 2007 Jul 17.PMID: 17636010 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of gap junctions in spontaneous activity of the rat bladder.

Ikeda Y, Fry C, Hayashi F, Stolz D, Griffiths D, Kanai A.

Am J Physiol Renal Physiol. 2007 Oct;293(4):F1018-25. Epub 2007 Jun 20.PMID: 17581924 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteome-wide prediction of novel DNA/RNA-binding proteins using amino acid composition and periodicity in the hyperthermophilic archaeon Pyrococcus furiosus.

Fujishima K, Komasa M, Kitamura S, Suzuki H, Tomita M, Kanai A.

DNA Res. 2007 Jun 30;14(3):91-102. Epub 2007 Jun 15.PMID: 17573465 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes.

Tsuritani K, Irie T, Yamashita R, Sakakibara Y, Wakaguri H, Kanai A, Mizushima-Sugano J, Sugano S, Nakai K, Suzuki Y.

Genome Res. 2007 Jul;17(7):1005-14. Epub 2007 Jun 13.PMID: 17567985 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrinsic promoter activities of primary DNA sequences in the human genome.

Sakakibara Y, Irie T, Suzuki Y, Yamashita R, Wakaguri H, Kanai A, Chiba J, Takagi T, Mizushima-Sugano J, Hashimoto S, Nakai K, Sugano S.

DNA Res. 2007 Apr;14(2):71-7. Epub 2007 May 23.PMID: 17522093 [PubMed - indexed for MEDLINE]Related articlesFree article

[Bioinformatics analyses of non-coding RNA]

Kochiwa H, Kanai A, Masaru T.

Tanpakushitsu Kakusan Koso. 2006 Dec;51(16 Suppl):2420-4. Review. Japanese. No abstract available. PMID: 17471957 [PubMed - indexed for MEDLINE]Related articles

Multiple high-throughput analyses monitor the response of E. coli to perturbations.

Ishii N, Nakahigashi K, Baba T, Robert M, Soga T, Kanai A, Hirasawa T, Naba M, Hirai K, Hoque A, Ho PY, Kakazu Y, Sugawara K, Igarashi S, Harada S, Masuda T, Sugiyama N, Togashi T, Hasegawa M, Takai Y, Yugi K, Arakawa K, Iwata N, Toya Y, Nakayama Y, Nishioka T, Shimizu K, Mori H, Tomita M.

Science. 2007 Apr 27;316(5824):593-7. Epub 2007 Mar 22.PMID: 17379776 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-neuronal acetylcholine and urinary bladder urothelium.

Hanna-Mitchell AT, Beckel JM, Barbadora S, Kanai AJ, de Groat WC, Birder LA.

Life Sci. 2007 May 30;80(24-25):2298-302. Epub 2007 Feb 20.PMID: 17363007 [PubMed - indexed for MEDLINE]Related articles

Synthetic study on telomerase inhibitor, D8646-2-6: synthesis of the key intermediate using Sn(OTf)2 or Sc(OTf)3 mediated aldol-type reaction and Stille coupling.

Kanai A, Takeda Y, Kuramochi K, Nakazaki A, Kobayashi S.

Chem Pharm Bull (Tokyo). 2007 Mar;55(3):495-9.PMID: 17329902 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of MnSOD-plasmid liposome gene therapy on antioxidant levels in irradiated murine oral cavity orthotopic tumors.

Epperly MW, Wegner R, Kanai AJ, Kagan V, Greenberger EE, Nie S, Greenberger JS.

Radiat Res. 2007 Mar;167(3):289-97.PMID: 17316075 [PubMed - indexed for MEDLINE]Related articles

SPLITS: a new program for predicting split and intron-containing tRNA genes at the genome level.

Sugahara J, Yachie N, Sekine Y, Soma A, Matsui M, Tomita M, Kanai A.

In Silico Biol. 2006;6(5):411-8.PMID: 17274770 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative analysis of cis-encoded antisense RNAs in eukaryotes.

Numata K, Okada Y, Saito R, Kiyosawa H, Kanai A, Tomita M.

Gene. 2007 May 1;392(1-2):134-41. Epub 2006 Dec 13.PMID: 17250976 [PubMed - indexed for MEDLINE]Related articles

Effectiveness of prostaglandin E1 for the treatment of patients with neuropathic pain following herpes zoster.

Kanai A, Osawa S, Suzuki A, Ishimaru R, Hoka S.

Pain Med. 2007 Jan-Feb;8(1):36-40.PMID: 17244102 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial targeting of radioprotectants using peptidyl conjugates.

Kanai A, Zabbarova I, Amoscato A, Epperly M, Xiao J, Wipf P.

Org Biomol Chem. 2007 Jan 21;5(2):307-9. Epub 2006 Dec 7.PMID: 17205174 [PubMed - indexed for MEDLINE]Related articles

Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists.

Kanai A, Roppolo J, Ikeda Y, Zabbarova I, Tai C, Birder L, Griffiths D, de Groat W, Fry C.

Am J Physiol Renal Physiol. 2007 Mar;292(3):F1065-72. Epub 2006 Nov 14.PMID: 17107944 [PubMed - indexed for MEDLINE]Related articlesFree article

Diverse DNA methylation statuses at alternative promoters of human genes in various tissues.

Cheong J, Yamada Y, Yamashita R, Irie T, Kanai A, Wakaguri H, Nakai K, Ito T, Saito I, Sugano S, Suzuki Y.

DNA Res. 2006 Aug 31;13(4):155-67. Epub 2006 Oct 26.PMID: 17068070 [PubMed - indexed for MEDLINE]Related articlesFree article