PubMed

Impact of Type 1 Diabetes and Insulin Treatment on Plasma Levels and Fractional Synthesis Rate of Retinol-Binding Protein 4.

Jourdan M, Jaleel A, Karakelides H, Ford GC, Kahn BB, Nair KS.

J Clin Endocrinol Metab. 2009 Oct 22. [Epub ahead of print]PMID: 19850685 [PubMed - as supplied by publisher]Related articles

Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis.

Preitner F, Mody N, Graham TE, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2009 Dec;297(6):E1420-9. Epub 2009 Oct 13.PMID: 19826103 [PubMed - in process]Related articles

Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis.

Hill JW, Xu Y, Preitner F, Fukuda M, Cho YR, Luo J, Balthasar N, Coppari R, Cantley LC, Kahn BB, Zhao JJ, Elmquist JK.

Endocrinology. 2009 Nov;150(11):4874-82. Epub 2009 Oct 9.PMID: 19819947 [PubMed - indexed for MEDLINE]Related articles

Retinol-binding protein 4 (RBP4): a biomarker for subclinical atherosclerosis?

Stuck BJ, Kahn BB.

Am J Hypertens. 2009 Sep;22(9):948-9. No abstract available. PMID: 19701163 [PubMed - in process]Related articles

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP.

Nat Med. 2009 Aug;15(8):940-5. Epub 2009 Jul 26.PMID: 19633655 [PubMed - indexed for MEDLINE]Related articles

Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues.

Xue B, Pulinilkunnil T, Murano I, Bence KK, He H, Minokoshi Y, Asakura K, Lee A, Haj F, Furukawa N, Catalano KJ, Delibegovic M, Balschi JA, Cinti S, Neel BG, Kahn BB.

Mol Cell Biol. 2009 Aug;29(16):4563-73. Epub 2009 Jun 15.PMID: 19528236 [PubMed - indexed for MEDLINE]Related articles

Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress.

Delibegovic M, Zimmer D, Kauffman C, Rak K, Hong EG, Cho YR, Kim JK, Kahn BB, Neel BG, Bence KK.

Diabetes. 2009 Mar;58(3):590-9. Epub 2008 Dec 15.PMID: 19074988 [PubMed - indexed for MEDLINE]Related articlesFree article

The relationship of retinol binding protein 4 to changes in insulin resistance and cardiometabolic risk in overweight black adolescents.

Goodman E, Graham TE, Dolan LM, Daniels SR, Goodman ER, Kahn BB.

J Pediatr. 2009 Jan;154(1):67-73.e1. Epub 2008 Sep 10.PMID: 18783798 [PubMed - indexed for MEDLINE]Related articles

Deletion of cd39/entpd1 results in hepatic insulin resistance.

Enjyoji K, Kotani K, Thukral C, Blumel B, Sun X, Wu Y, Imai M, Friedman D, Csizmadia E, Bleibel W, Kahn BB, Robson SC.

Diabetes. 2008 Sep;57(9):2311-20. Epub 2008 Jun 20.PMID: 18567823 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum concentrations of retinol-binding protein 4 in women with and without gestational diabetes.

Krzyzanowska K, Zemany L, Krugluger W, Schernthaner GH, Mittermayer F, Schnack C, Rahman R, Brix J, Kahn BB, Schernthaner G.

Diabetologia. 2008 Jul;51(7):1115-22. Epub 2008 Apr 25.PMID: 18437353 [PubMed - indexed for MEDLINE]Related articlesFree article

High circulating levels of RBP4 and mRNA levels of aP2, PGC-1alpha and UCP-2 predict improvement in insulin sensitivity following pioglitazone treatment of drug-naïve type 2 diabetic subjects.

Hammarstedt A, Pihlajamäki J, Graham TE, Kainulainen S, Kahn BB, Laakso M, Smith U.

J Intern Med. 2008 Apr;263(4):440-9.PMID: 18324929 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice.

Mody N, Graham TE, Tsuji Y, Yang Q, Kahn BB.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E785-93. Epub 2008 Feb 19.PMID: 18285525 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo.

Zabolotny JM, Kim YB, Welsh LA, Kershaw EE, Neel BG, Kahn BB.

J Biol Chem. 2008 May 23;283(21):14230-41. Epub 2008 Feb 14.PMID: 18281274 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific alterations of glucose transport and molecular mechanisms of intertissue communication in obesity and type 2 diabetes.

Graham TE, Kahn BB.

Horm Metab Res. 2007 Oct;39(10):717-21. Review.PMID: 17952832 [PubMed - indexed for MEDLINE]Related articles

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.

Kovacs P, Geyer M, Berndt J, Klöting N, Graham TE, Böttcher Y, Enigk B, Tönjes A, Schleinitz D, Schön MR, Kahn BB, Blüher M, Stumvoll M.

Diabetes. 2007 Dec;56(12):3095-100. Epub 2007 Aug 29.PMID: 17728376 [PubMed - indexed for MEDLINE]Related articlesFree article

Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

Delibegovic M, Bence KK, Mody N, Hong EG, Ko HJ, Kim JK, Kahn BB, Neel BG.

Mol Cell Biol. 2007 Nov;27(21):7727-34. Epub 2007 Aug 27.PMID: 17724080 [PubMed - indexed for MEDLINE]Related articlesFree article

Cathepsin L activity controls adipogenesis and glucose tolerance.

Yang M, Zhang Y, Pan J, Sun J, Liu J, Libby P, Sukhova GK, Doria A, Katunuma N, Peroni OD, Guerre-Millo M, Kahn BB, Clement K, Shi GP.

Nat Cell Biol. 2007 Aug;9(8):970-7. Epub 2007 Jul 22.PMID: 17643114 [PubMed - indexed for MEDLINE]Related articles

The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome.

Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S, Cline GW, Befroy D, Zemany L, Kahn BB, Papademetris X, Rothman DL, Shulman GI.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12587-94. Epub 2007 Jul 18.PMID: 17640906 [PubMed - indexed for MEDLINE]Related articlesFree article

The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance.

Yan QW, Yang Q, Mody N, Graham TE, Hsu CH, Xu Z, Houstis NE, Kahn BB, Rosen ED.

Diabetes. 2007 Oct;56(10):2533-40. Epub 2007 Jul 16.PMID: 17639021 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.

Klöting N, Graham TE, Berndt J, Kralisch S, Kovacs P, Wason CJ, Fasshauer M, Schön MR, Stumvoll M, Blüher M, Kahn BB.

Cell Metab. 2007 Jul;6(1):79-87.PMID: 17618858 [PubMed - indexed for MEDLINE]Related articles

Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance.

Xue B, Kim YB, Lee A, Toschi E, Bonner-Weir S, Kahn CR, Neel BG, Kahn BB.

J Biol Chem. 2007 Aug 17;282(33):23829-40. Epub 2007 Jun 1.PMID: 17545163 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of gluconeogenesis by Krüppel-like factor 15.

Gray S, Wang B, Orihuela Y, Hong EG, Fisch S, Haldar S, Cline GW, Kim JK, Peroni OD, Kahn BB, Jain MK.

Cell Metab. 2007 Apr;5(4):305-12.PMID: 17403374 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation.

Balagopal P, Graham TE, Kahn BB, Altomare A, Funanage V, George D.

J Clin Endocrinol Metab. 2007 May;92(5):1971-4. Epub 2007 Mar 6.PMID: 17341558 [PubMed - indexed for MEDLINE]Related articlesFree article

A high-fat, ketogenic diet induces a unique metabolic state in mice.

Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1724-39. Epub 2007 Feb 13. Erratum in: Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1846. Roberson, Russell [added]. Am J Physiol Endocrinol Metab. 2009 May;296(5):E1179. PMID: 17299079 [PubMed - indexed for MEDLINE]Related articlesFree article

Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects.

Graham TE, Wason CJ, Blüher M, Kahn BB.

Diabetologia. 2007 Apr;50(4):814-23. Epub 2007 Feb 9.PMID: 17294166 [PubMed - indexed for MEDLINE]Related articles

Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia.

Alquier T, Kawashima J, Tsuji Y, Kahn BB.

Endocrinology. 2007 Mar;148(3):1367-75. Epub 2006 Dec 21.PMID: 17185376 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuronal PTP1B regulates body weight, adiposity and leptin action.

Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG, Kahn BB.

Nat Med. 2006 Aug;12(8):917-24. Epub 2006 Jul 16.PMID: 16845389 [PubMed - indexed for MEDLINE]Related articles

Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony.

Herman MA, Kahn BB.

J Clin Invest. 2006 Jul;116(7):1767-75. Review.PMID: 16823474 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects.

Graham TE, Yang Q, Blüher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Jansson PA, Smith U, Kahn BB.

N Engl J Med. 2006 Jun 15;354(24):2552-63.PMID: 16775236 [PubMed - indexed for MEDLINE]Related articlesFree article

mTOR tells the brain that the body is hungry.

Kahn BB, Myers MG Jr.

Nat Med. 2006 Jun;12(6):615-7. No abstract available. PMID: 16761005 [PubMed - indexed for MEDLINE]Related articles

AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues.

Xue B, Kahn BB.

J Physiol. 2006 Jul 1;574(Pt 1):73-83. Epub 2006 May 18. Review.PMID: 16709629 [PubMed - indexed for MEDLINE]Related articlesFree article

Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle.

Martin TL, Alquier T, Asakura K, Furukawa N, Preitner F, Kahn BB.

J Biol Chem. 2006 Jul 14;281(28):18933-41. Epub 2006 May 10.PMID: 16687413 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism.

Kim YB, Peroni OD, Aschenbach WG, Minokoshi Y, Kotani K, Zisman A, Kahn CR, Goodyear LJ, Kahn BB.

Mol Cell Biol. 2005 Nov;25(21):9713-23.PMID: 16227617 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of Rho-kinase in regulation of insulin action and glucose homeostasis.

Furukawa N, Ongusaha P, Jahng WJ, Araki K, Choi CS, Kim HJ, Lee YH, Kaibuchi K, Kahn BB, Masuzaki H, Kim JK, Lee SW, Kim YB.

Cell Metab. 2005 Aug;2(2):119-29.PMID: 16098829 [PubMed - indexed for MEDLINE]Related articles

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes.

Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, Uysal KT, Cao Q, Atsumi G, Malone H, Krishnan B, Minokoshi Y, Kahn BB, Parker RA, Hotamisligil GS.

Cell Metab. 2005 Feb;1(2):107-19.PMID: 16054052 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.

Kahn BB, Alquier T, Carling D, Hardie DG.

Cell Metab. 2005 Jan;1(1):15-25. Review.PMID: 16054041 [PubMed - indexed for MEDLINE]Related articles

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes.

Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L, Kahn BB.

Nature. 2005 Jul 21;436(7049):356-62.PMID: 16034410 [PubMed - indexed for MEDLINE]Related articles

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle.

Carvalho E, Kotani K, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E551-61. Epub 2005 May 31.PMID: 15928024 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance.

Jones JR, Barrick C, Kim KA, Lindner J, Blondeau B, Fujimoto Y, Shiota M, Kesterson RA, Kahn BB, Magnuson MA.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6207-12. Epub 2005 Apr 15.PMID: 15833818 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue.

Kurlawalla-Martinez C, Stiles B, Wang Y, Devaskar SU, Kahn BB, Wu H.

Mol Cell Biol. 2005 Mar;25(6):2498-510.PMID: 15743841 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice.

Haj FG, Zabolotny JM, Kim YB, Kahn BB, Neel BG.

J Biol Chem. 2005 Apr 15;280(15):15038-46. Epub 2005 Feb 7.PMID: 15699041 [PubMed - indexed for MEDLINE]Related articlesFree article

Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP.

Galic S, Hauser C, Kahn BB, Haj FG, Neel BG, Tonks NK, Tiganis T.

Mol Cell Biol. 2005 Jan;25(2):819-29.PMID: 15632081 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling.

Corbould A, Kim YB, Youngren JF, Pender C, Kahn BB, Lee A, Dunaif A.

Am J Physiol Endocrinol Metab. 2005 May;288(5):E1047-54. Epub 2004 Dec 21.PMID: 15613682 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and regulates soluble tumor necrosis factor-alpha receptor levels in humans with relative leptin deficiency.

Chan JL, Moschos SJ, Bullen J, Heist K, Li X, Kim YB, Kahn BB, Mantzoros CS.

J Clin Endocrinol Metab. 2005 Mar;90(3):1625-31. Epub 2004 Dec 21.PMID: 15613409 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.

Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB.

J Clin Invest. 2004 Dec;114(11):1666-75.PMID: 15578099 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland.

Morroni M, Giordano A, Zingaretti MC, Boiani R, De Matteis R, Kahn BB, Nisoli E, Tonello C, Pisoschi C, Luchetti MM, Marelli M, Cinti S.

Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16801-6. Epub 2004 Nov 19.PMID: 15556998 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrient sensor links obesity with diabetes risk.

Patti ME, Kahn BB.

Nat Med. 2004 Oct;10(10):1049-50. No abstract available. PMID: 15459705 [PubMed - indexed for MEDLINE]Related articles

Peripheral signals set the tone for central regulation of metabolism.

Alquier T, Kahn BB.

Endocrinology. 2004 Sep;145(9):4022-4. Review. No abstract available. PMID: 15321948 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice.

Lamia KA, Peroni OD, Kim YB, Rameh LE, Kahn BB, Cantley LC.

Mol Cell Biol. 2004 Jun;24(11):5080-7.PMID: 15143198 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression.

Blüher M, Patti ME, Gesta S, Kahn BB, Kahn CR.

J Biol Chem. 2004 Jul 23;279(30):31891-901. Epub 2004 May 6.PMID: 15131119 [PubMed - indexed for MEDLINE]Related articlesFree article