PubMed

Role of Insulin-Like Growth Factor-Binding Protein 5 (IGFBP5) in Organismal and Pancreatic {beta}-Cell Growth.

Gleason CE, Ning Y, Cominski TP, Gupta R, Kaestner KH, Pintar JE, Birnbaum MJ.

Mol Endocrinol. 2009 Nov 6. [Epub ahead of print]PMID: 19897600 [PubMed - as supplied by publisher]Related articles

Foxl1 promotes liver repair following cholestatic injury in mice.

Sackett SD, Gao Y, Shin S, Esterson YB, Tsingalia A, Hurtt RS, Brondell K, Kaestner KH, Greenbaum LE.

Lab Invest. 2009 Oct 19. [Epub ahead of print]PMID: 19841618 [PubMed - as supplied by publisher]Related articles

KLF family members regulate intrinsic axon regeneration ability.

Moore DL, Blackmore MG, Hu Y, Kaestner KH, Bixby JL, Lemmon VP, Goldberg JL.

Science. 2009 Oct 9;326(5950):298-301.PMID: 19815778 [PubMed - indexed for MEDLINE]Related articles

An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion.

Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Kajimura D, Myers MG Jr, Chua SC Jr, Wang Q, Kim JK, Kaestner KH, Karsenty G.

Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1:E20-30.PMID: 19751411 [PubMed - indexed for MEDLINE]Related articles

Foxa1 and Foxa2 Control the Differentiation of Goblet and Enteroendocrine L- and D-Cells in Mice.

Ye DZ, Kaestner KH.

Gastroenterology. 2009 Sep 6. [Epub ahead of print]PMID: 19737569 [PubMed - as supplied by publisher]Related articles

Sox17 regulates organ lineage segregation of ventral foregut progenitor cells.

Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM.

Dev Cell. 2009 Jul;17(1):62-74.PMID: 19619492 [PubMed - indexed for MEDLINE]Related articles

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.

Lin W, Metzakopian E, Mavromatakis YE, Gao N, Balaskas N, Sasaki H, Briscoe J, Whitsett JA, Goulding M, Kaestner KH, Ang SL.

Dev Biol. 2009 Sep 15;333(2):386-96. Epub 2009 Jul 14.PMID: 19607821 [PubMed - indexed for MEDLINE]Related articles

CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis.

Le Lay J, Tuteja G, White P, Dhir R, Ahima R, Kaestner KH.

Cell Metab. 2009 Jul;10(1):55-62.PMID: 19583954 [PubMed - indexed for MEDLINE]Related articles

The transcriptional response of the islet to pregnancy in mice.

Rieck S, White P, Schug J, Fox AJ, Smirnova O, Gao N, Gupta RK, Wang ZV, Scherer PE, Keller MP, Attie AD, Kaestner KH.

Mol Endocrinol. 2009 Oct;23(10):1702-12. Epub 2009 Jul 2.PMID: 19574445 [PubMed - in process]Related articles

In the zone: how a hepatocyte knows where it is.

Kaestner KH.

Gastroenterology. 2009 Aug;137(2):425-7. Epub 2009 Jun 30. No abstract available. PMID: 19573634 [PubMed - indexed for MEDLINE]Related articles

The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse.

Zheng K, Wu X, Kaestner KH, Wang PJ.

BMC Dev Biol. 2009 Jun 29;9:38.PMID: 19563657 [PubMed - indexed for MEDLINE]Related articlesFree article

Extracting transcription factor targets from ChIP-Seq data.

Tuteja G, White P, Schug J, Kaestner KH.

Nucleic Acids Res. 2009 Sep;37(17):e113. Epub 2009 Jun 24.PMID: 19553195 [PubMed - in process]Related articlesFree article

Krüppel-like factor 4, a "pluripotency transcription factor" highly expressed in male postmeiotic germ cells, is dispensable for spermatogenesis in the mouse.

Godmann M, Gashaw I, Katz JP, Nagy A, Kaestner KH, Behr R.

Mech Dev. 2009 Aug-Sep;126(8-9):650-64. Epub 2009 Jun 17.PMID: 19539755 [PubMed - in process]Related articles

Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development.

High FA, Jain R, Stoller JZ, Antonucci NB, Lu MM, Loomes KM, Kaestner KH, Pear WS, Epstein JA.

J Clin Invest. 2009 Jul;119(7):1986-96. doi: 10.1172/JCI38922. Epub 2009 Jun 8.PMID: 19509466 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression analysis in diabetes research.

White P, Kaestner KH.

Methods Mol Biol. 2009;560:239-61.PMID: 19504254 [PubMed - in process]Related articles

Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas.

Golson ML, Le Lay J, Gao N, Brämswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH.

Mech Dev. 2009 Aug-Sep;126(8-9):687-99. Epub 2009 Jun 6.PMID: 19501159 [PubMed - in process]Related articles

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.

Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA.

J Clin Invest. 2009 Jul;119(7):1888-98.PMID: 19487809 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxa1 and Foxa2 regulate bile duct development in mice.

Li Z, White P, Tuteja G, Rubins N, Sackett S, Kaestner KH.

J Clin Invest. 2009 Jun;119(6):1537-45. doi: 10.1172/JCI38201. Epub 2009 May 11.PMID: 19436110 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxa2-dependent hepatic gene regulatory networks depend on physiological state.

Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH.

Physiol Genomics. 2009 Jul 9;38(2):186-95. Epub 2009 May 5.PMID: 19417011 [PubMed - indexed for MEDLINE]Related articles

Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.

Gao N, White P, Kaestner KH.

Dev Cell. 2009 Apr;16(4):588-99.PMID: 19386267 [PubMed - indexed for MEDLINE]Related articles

The evolution of Fox genes and their role in development and disease.

Hannenhalli S, Kaestner KH.

Nat Rev Genet. 2009 Apr;10(4):233-40. Review.PMID: 19274050 [PubMed - indexed for MEDLINE]Related articlesFree article

Ductal malformation and pancreatitis in mice caused by conditional Jag1 deletion.

Golson ML, Loomes KM, Oakey R, Kaestner KH.

Gastroenterology. 2009 May;136(5):1761-71.e1. Epub 2009 Jan 23.PMID: 19208348 [PubMed - indexed for MEDLINE]Related articles

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48.PMID: 19141476 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxl1 is a marker of bipotential hepatic progenitor cells in mice.

Sackett SD, Li Z, Hurtt R, Gao Y, Wells RG, Brondell K, Kaestner KH, Greenbaum LE.

Hepatology. 2009 Mar;49(3):920-9.PMID: 19105206 [PubMed - indexed for MEDLINE]Related articles

The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity.

Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Myers MG Jr, Chua SC Jr, Kim JK, Kaestner KH, Karsenty G.

J Cell Biol. 2008 Dec 29;183(7):1235-42. Epub 2008 Dec 22.PMID: 19103808 [PubMed - indexed for MEDLINE]Related articlesFree article

Limited effects of fasting on hepatitis B virus (HBV) biosynthesis in HBV transgenic mice.

Li L, Oropeza CE, Kaestner KH, McLachlan A.

J Virol. 2009 Feb;83(4):1682-8. Epub 2008 Dec 10.PMID: 19073739 [PubMed - indexed for MEDLINE]Related articlesFree article

FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.

Madison BB, McKenna LB, Dolson D, Epstein DJ, Kaestner KH.

J Biol Chem. 2009 Feb 27;284(9):5936-44. Epub 2008 Dec 2.PMID: 19049965 [PubMed - indexed for MEDLINE]Related articles

A two-step pathway to resist fasting.

Kaestner KH.

Cell Metab. 2008 Dec;8(6):449-51.PMID: 19041759 [PubMed - indexed for MEDLINE]Related articles

Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology.

Alenghat T, Meyers K, Mullican SE, Leitner K, Adeniji-Adele A, Avila J, Bućan M, Ahima RS, Kaestner KH, Lazar MA.

Nature. 2008 Dec 18;456(7224):997-1000. Epub 2008 Nov 26.PMID: 19037247 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly.

Gkretsi V, Apte U, Mars WM, Bowen WC, Luo JH, Yang Y, Yu YP, Orr A, St-Arnaud R, Dedhar S, Kaestner KH, Wu C, Michalopoulos GK.

Hepatology. 2008 Dec;48(6):1932-41.PMID: 18846549 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress.

Bochkis IM, Rubins NE, White P, Furth EE, Friedman JR, Kaestner KH.

Nat Med. 2008 Aug;14(8):828-36. Epub 2008 Jul 27.PMID: 18660816 [PubMed - indexed for MEDLINE]Related articles

Distinct proliferative and transcriptional effects of the D-type cyclins in vivo.

Mullany LK, White P, Hanse EA, Nelsen CJ, Goggin MM, Mullany JE, Anttila CK, Greenbaum LE, Kaestner KH, Albrecht JH.

Cell Cycle. 2008 Jul 15;7(14):2215-24. Epub 2008 May 12.PMID: 18635970 [PubMed - indexed for MEDLINE]Related articlesFree article

Cis-regulatory modules in the mammalian liver: composition depends on strength of Foxa2 consensus site.

Tuteja G, Jensen ST, White P, Kaestner KH.

Nucleic Acids Res. 2008 Jul;36(12):4149-57. Epub 2008 Jun 13.PMID: 18556755 [PubMed - indexed for MEDLINE]Related articlesFree article

Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury.

Yoshida T, Kaestner KH, Owens GK.

Circ Res. 2008 Jun 20;102(12):1548-57. Epub 2008 May 15.PMID: 18483411 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development.

Tan X, Yuan Y, Zeng G, Apte U, Thompson MD, Cieply B, Stolz DB, Michalopoulos GK, Kaestner KH, Monga SP.

Hepatology. 2008 May;47(5):1667-79.PMID: 18393386 [PubMed - indexed for MEDLINE]Related articles

KLF4 is a FOXO target gene that suppresses B cell proliferation.

Yusuf I, Kharas MG, Chen J, Peralta RQ, Maruniak A, Sareen P, Yang VW, Kaestner KH, Fruman DA.

Int Immunol. 2008 May;20(5):671-81. Epub 2008 Mar 28.PMID: 18375530 [PubMed - indexed for MEDLINE]Related articles

Germline expression of mammalian CTF18, an evolutionarily conserved protein required for germ cell proliferation in the fly and sister chromatid cohesion in yeast.

Berkowitz KM, Kaestner KH, Jongens TA.

Mol Hum Reprod. 2008 Mar;14(3):143-50. Epub 2008 Feb 4.PMID: 18250106 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development.

High FA, Lu MM, Pear WS, Loomes KM, Kaestner KH, Epstein JA.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1955-9. Epub 2008 Feb 1.PMID: 18245384 [PubMed - indexed for MEDLINE]Related articlesFree article

Krüppel-like factor 4 is involved in functional differentiation of testicular Sertoli cells.

Godmann M, Katz JP, Guillou F, Simoni M, Kaestner KH, Behr R.

Dev Biol. 2008 Mar 15;315(2):552-66. Epub 2008 Feb 20.PMID: 18243172 [PubMed - indexed for MEDLINE]Related articlesFree article

Defining pancreatic endocrine precursors and their descendants.

White P, May CL, Lamounier RN, Brestelli JE, Kaestner KH.

Diabetes. 2008 Mar;57(3):654-68. Epub 2007 Dec 10.PMID: 18071024 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle.

Chandler RJ, Sloan J, Fu H, Tsai M, Stabler S, Allen R, Kaestner KH, Kazazian HH, Venditti CP.

BMC Med Genet. 2007 Oct 15;8:64.PMID: 17937813 [PubMed - indexed for MEDLINE]Related articlesFree article

Forkhead transcription factors II.

Tuteja G, Kaestner KH.

Cell. 2007 Oct 5;131(1):192. No abstract available. PMID: 17923097 [PubMed - indexed for MEDLINE]Related articles

Foxa2 controls vesicle docking and insulin secretion in mature Beta cells.

Gao N, White P, Doliba N, Golson ML, Matschinsky FM, Kaestner KH.

Cell Metab. 2007 Oct;6(4):267-79.PMID: 17908556 [PubMed - indexed for MEDLINE]Related articles

SnapShot: forkhead transcription factors I.

Tuteja G, Kaestner KH.

Cell. 2007 Sep 21;130(6):1160. No abstract available. PMID: 17889656 [PubMed - indexed for MEDLINE]Related articles

Krüppel-like factor 4 regulates B cell number and activation-induced B cell proliferation.

Klaewsongkram J, Yang Y, Golech S, Katz J, Kaestner KH, Weng NP.

J Immunol. 2007 Oct 1;179(7):4679-84.PMID: 17878366 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta cell transplantation and immunosuppression: can't live with it, can't live without it.

Kaestner KH.

J Clin Invest. 2007 Sep;117(9):2380-2.PMID: 17786232 [PubMed - indexed for MEDLINE]Related articlesFree article

The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation.

Feinberg MW, Wara AK, Cao Z, Lebedeva MA, Rosenbauer F, Iwasaki H, Hirai H, Katz JP, Haspel RL, Gray S, Akashi K, Segre J, Kaestner KH, Tenen DG, Jain MK.

EMBO J. 2007 Sep 19;26(18):4138-48. Epub 2007 Aug 30.PMID: 17762869 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy.

Keller DM, McWeeney S, Arsenlis A, Drouin J, Wright CV, Wang H, Wollheim CB, White P, Kaestner KH, Goodman RH.

J Biol Chem. 2007 Nov 2;282(44):32084-92. Epub 2007 Aug 30.PMID: 17761679 [PubMed - indexed for MEDLINE]Related articlesFree article

Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.

Ghaleb AM, McConnell BB, Nandan MO, Katz JP, Kaestner KH, Yang VW.

Cancer Res. 2007 Aug 1;67(15):7147-54.PMID: 17671182 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxl1-Cre BAC transgenic mice: a new tool for gene ablation in the gastrointestinal mesenchyme.

Sackett SD, Fulmer JT, Friedman JR, Kaestner KH.

Genesis. 2007 Aug;45(8):518-22.PMID: 17661401 [PubMed - indexed for MEDLINE]Related articles