PubMed

Per2 Is a C/EBP Target Gene Implicated in Myeloid Leukemia.

Gery S, Koeffler HP.

Integr Cancer Ther. 2009 Nov 18. [Epub ahead of print]PMID: 19926610 [PubMed - as supplied by publisher]Related articles

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway.

Thoennissen NH, O'Kelly J, Lu D, Iwanski GB, La DT, Abbassi S, Leiter A, Karlan B, Mehta R, Koeffler HP.

Oncogene. 2009 Oct 26. [Epub ahead of print]PMID: 19855437 [PubMed - as supplied by publisher]Related articles

Analysis of Aurora B kinase in non-Hodgkin lymphoma.

Ikezoe T, Takeuchi T, Yang J, Adachi Y, Nishioka C, Furihata M, Koeffler HP, Yokoyama A.

Lab Invest. 2009 Dec;89(12):1364-73. Epub 2009 Oct 12.PMID: 19823168 [PubMed - in process]Related articles

Functional variant of KLOTHO: a breast cancer risk modifier among BRCA1 mutation carriers of Ashkenazi origin.

Wolf I, Laitman Y, Rubinek T, Abramovitz L, Novikov I, Beeri R, Kuro-O M, Koeffler HP, Catane R, Freedman LS, Levy-Lahad E, Karlan BY, Friedman E, Kaufman B.

Oncogene. 2009 Oct 5. [Epub ahead of print]PMID: 19802015 [PubMed - as supplied by publisher]Related articles

A role for the clock gene per1 in prostate cancer.

Cao Q, Gery S, Dashti A, Yin D, Zhou Y, Gu J, Koeffler HP.

Cancer Res. 2009 Oct 1;69(19):7619-25. Epub 2009 Sep 14.PMID: 19752089 [PubMed - in process]Related articles

Single nucleotide polymorphism genomic arrays analysis of t(8;21) acute myeloid leukemia cells.

Akagi T, Shih LY, Ogawa S, Gerss J, Moore SR, Schreck R, Kawamata N, Liang DC, Sanada M, Nannya Y, Deneberg S, Zachariadis V, Nordgren A, Song JH, Dugas M, Lehmann S, Koeffler HP.

Haematologica. 2009 Sep;94(9):1301-6.PMID: 19734423 [PubMed - in process]Related articlesFree article

Induction of endoplasmic reticulum stress response by TZD18, a novel dual ligand for peroxisome proliferator-activated receptor alpha/gamma, in human breast cancer cells.

Zang C, Liu H, Bertz J, Possinger K, Koeffler HP, Elstner E, Eucker J.

Mol Cancer Ther. 2009 Aug;8(8):2296-307. Epub 2009 Aug 11.PMID: 19671747 [PubMed - in process]Related articles

Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.

Akagi T, Ito T, Kato M, Jin Z, Cheng Y, Kan T, Yamamoto G, Olaru A, Kawamata N, Boult J, Soukiasian HJ, Miller CW, Ogawa S, Meltzer SJ, Koeffler HP.

Int J Cancer. 2009 Nov 15;125(10):2349-59.PMID: 19670330 [PubMed - indexed for MEDLINE]Related articles

Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.

Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S.

Nature. 2009 Aug 13;460(7257):904-8. Epub 2009 Jul 20.PMID: 19620960 [PubMed - indexed for MEDLINE]Related articles

Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates.

Gombart AF, Saito T, Koeffler HP.

BMC Genomics. 2009 Jul 16;10:321.PMID: 19607716 [PubMed - indexed for MEDLINE]Related articlesFree article

Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.

Thoennissen NH, Iwanski GB, Doan NB, Okamoto R, Lin P, Abbassi S, Song JH, Yin D, Toh M, Xie WD, Said JW, Koeffler HP.

Cancer Res. 2009 Jul 15;69(14):5876-84.PMID: 19605406 [PubMed - indexed for MEDLINE]Related articles

Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells.

Nishioka C, Ikezoe T, Yang J, Gery S, Koeffler HP, Yokoyama A.

Int J Cancer. 2009 Oct 1;125(7):1710-20.PMID: 19507250 [PubMed - indexed for MEDLINE]Related articles

Identified hidden genomic changes in mantle cell lymphoma using high-resolution single nucleotide polymorphism genomic array.

Kawamata N, Ogawa S, Gueller S, Ross SH, Huynh T, Chen J, Chang A, Nabavi-Nouis S, Megrabian N, Siebert R, Martinez-Climent JA, Koeffler HP.

Exp Hematol. 2009 Aug;37(8):937-46. Epub 2009 May 27.PMID: 19477219 [PubMed - indexed for MEDLINE]Related articles

High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray.

Yin D, Ogawa S, Kawamata N, Tunici P, Finocchiaro G, Eoli M, Ruckert C, Huynh T, Liu G, Kato M, Sanada M, Jauch A, Dugas M, Black KL, Koeffler HP.

Mol Cancer Res. 2009 May;7(5):665-77. Epub 2009 May 12.PMID: 19435819 [PubMed - indexed for MEDLINE]Related articles

Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia.

Kawamata N, Ogawa S, Seeger K, Kirschner-Schwabe R, Huynh T, Chen J, Megrabian N, Harbott J, Zimmermann M, Henze G, Schrappe M, Bartram CR, Koeffler HP.

Int J Oncol. 2009 Jun;34(6):1603-12.PMID: 19424578 [PubMed - indexed for MEDLINE]Related articles

Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells.

Nishioka C, Ikezoe T, Yang J, Komatsu N, Koeffler HP, Yokoyama A.

Int J Cancer. 2009 Sep 1;125(5):1168-76.PMID: 19422044 [PubMed - indexed for MEDLINE]Related articles

A novel treatment strategy targeting polo-like kinase 1 in hematological malignancies.

Ikezoe T, Yang J, Nishioka C, Takezaki Y, Tasaka T, Togitani K, Koeffler HP, Yokoyama A.

Leukemia. 2009 Sep;23(9):1564-76. Epub 2009 May 7.PMID: 19421227 [PubMed - indexed for MEDLINE]Related articles

Expression of the adaptor protein Lnk in leukemia cells.

Gery S, Gueller S, Nowak V, Sohn J, Hofmann WK, Koeffler HP.

Exp Hematol. 2009 May;37(5):585-592.e2.PMID: 19375649 [PubMed - indexed for MEDLINE]Related articles

Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F.

Gery S, Cao Q, Gueller S, Xing H, Tefferi A, Koeffler HP.

J Leukoc Biol. 2009 Jun;85(6):957-65. Epub 2009 Mar 17.PMID: 19293402 [PubMed - indexed for MEDLINE]Related articles

Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy.

Nowak D, Le Toriellec E, Stern MH, Kawamata N, Akagi T, Dyer MJ, Hofmann WK, Ogawa S, Koeffler HP.

Haematologica. 2009 Apr;94(4):518-27. Epub 2009 Mar 10.PMID: 19278963 [PubMed - indexed for MEDLINE]Related articlesFree article

Differentiation therapy of leukemia: 3 decades of development.

Nowak D, Stewart D, Koeffler HP.

Blood. 2009 Apr 16;113(16):3655-65. Epub 2009 Feb 12. Review.PMID: 19221035 [PubMed - indexed for MEDLINE]Related articles

Role of caspases in 5-FU and selenium-induced growth inhibition of colorectal cancer cells.

Thant AA, Wu Y, Lee J, Mishra DK, Garcia H, Koeffler HP, Vadgama JV.

Anticancer Res. 2008 Nov-Dec;28(6A):3579-92.PMID: 19189638 [PubMed - indexed for MEDLINE]Related articles

Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotype.

Akagi T, Ogawa S, Dugas M, Kawamata N, Yamamoto G, Nannya Y, Sanada M, Miller CW, Yung A, Schnittger S, Haferlach T, Haferlach C, Koeffler HP.

Haematologica. 2009 Feb;94(2):213-23. Epub 2009 Jan 14.PMID: 19144660 [PubMed - indexed for MEDLINE]Related articlesFree article

Low plasma level of cathelicidin antimicrobial peptide (hCAP18) predicts increased infectious disease mortality in patients undergoing hemodialysis.

Gombart AF, Bhan I, Borregaard N, Tamez H, Camargo CA Jr, Koeffler HP, Thadhani R.

Clin Infect Dis. 2009 Feb 15;48(4):418-24.PMID: 19133797 [PubMed - indexed for MEDLINE]Related articles

Compound 48, a novel dual PPAR alpha/gamma ligand, inhibits the growth of human CML cell lines and enhances the anticancer-effects of imatinib.

Bertz J, Zang C, Liu H, Wächter M, Possinger K, Koeffler HP, Elstner E.

Leuk Res. 2009 May;33(5):686-92. Epub 2009 Jan 7.PMID: 19131110 [PubMed - indexed for MEDLINE]Related articles

Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations.

Akagi T, Shih LY, Kato M, Kawamata N, Yamamoto G, Sanada M, Okamoto R, Miller CW, Liang DC, Ogawa S, Koeffler HP.

Blood. 2009 Feb 19;113(8):1741-8. Epub 2008 Dec 23.PMID: 19109227 [PubMed - indexed for MEDLINE]Related articles

Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.

Akagi T, Yin D, Kawamata N, Bartram CR, Hofmann WK, Song JH, Miller CW, den Boer ML, Koeffler HP.

Leuk Res. 2009 Jul;33(7):991-6. Epub 2008 Dec 2.PMID: 19054556 [PubMed - indexed for MEDLINE]Related articles

Genome-wide loss of heterozygosity and uniparental disomy in BRCA1/2-associated ovarian carcinomas.

Walsh CS, Ogawa S, Scoles DR, Miller CW, Kawamata N, Narod SA, Koeffler HP, Karlan BY.

Clin Cancer Res. 2008 Dec 1;14(23):7645-51.PMID: 19047089 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells.

Kumagai T, Akagi T, Desmond JC, Kawamata N, Gery S, Imai Y, Song JH, Gui D, Said J, Koeffler HP.

Int J Cancer. 2009 Feb 15;124(4):827-33.PMID: 19035457 [PubMed - indexed for MEDLINE]Related articles

Novel acyl sulfonamide LY573636-sodium: effect on hematopoietic malignant cells.

Haritunians T, Gueller S, O'Kelly J, Ilaria R Jr, Koeffler HP.

Oncol Rep. 2008 Nov;20(5):1237-42.PMID: 18949427 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel Gemini vitamin D(3) analogs have potent antitumor activity.

Saito T, Okamoto R, Haritunians T, O'Kelly J, Uskokovic M, Maehr H, Marczak S, Jankowski P, Badr R, Koeffler HP.

J Steroid Biochem Mol Biol. 2008 Nov;112(1-3):151-6. Epub 2008 Sep 30.PMID: 18938245 [PubMed - indexed for MEDLINE]Related articlesFree article

Double minute chromosomes containing MYB gene and NUP214-ABL1 fusion gene in T-cell leukemia detected by single nucleotide polymorphism DNA microarray and fluorescence in situ hybridization.

Kawamata N, Zhang L, Ogawa S, Nannya Y, Dashti A, Lu D, Lim S, Schreck R, Koeffler HP.

Leuk Res. 2009 Apr;33(4):569-71. Epub 2008 Sep 16. No abstract available. PMID: 18799215 [PubMed - indexed for MEDLINE]Related articles

Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells.

Nishioka C, Ikezoe T, Yang J, Koeffler HP, Yokoyama A.

Leukemia. 2008 Dec;22(12):2159-68. Epub 2008 Sep 11.PMID: 18784743 [PubMed - indexed for MEDLINE]Related articles

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer.

Wolf I, Levanon-Cohen S, Bose S, Ligumsky H, Sredni B, Kanety H, Kuro-o M, Karlan B, Kaufman B, Koeffler HP, Rubinek T.

Oncogene. 2008 Nov 27;27(56):7094-105. Epub 2008 Sep 1.PMID: 18762812 [PubMed - indexed for MEDLINE]Related articles

Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase.

Wakimoto N, Wolf I, Yin D, O'Kelly J, Akagi T, Abramovitz L, Black KL, Tai HH, Koeffler HP.

Cancer Res. 2008 Sep 1;68(17):6978-86.PMID: 18757412 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray.

Kawamata N, Ogawa S, Yamamoto G, Lehmann S, Levine RL, Pikman Y, Nannya Y, Sanada M, Miller CW, Gilliland DG, Koeffler HP.

Exp Hematol. 2008 Nov;36(11):1471-9. Epub 2008 Aug 23.PMID: 18723266 [PubMed - indexed for MEDLINE]Related articles

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.

Kawamata N, Ogawa S, Zimmermann M, Niebuhr B, Stocking C, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR, Koeffler HP.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11921-6. Epub 2008 Aug 12.PMID: 18697940 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of sodium iodide symporter gene and molecular characterisation of HNF3 beta/FoxA2, TTF-1 and C/EBP beta in thyroid carcinoma cells.

Akagi T, Luong QT, Gui D, Said J, Selektar J, Yung A, Bunce CM, Braunstein GD, Koeffler HP.

Br J Cancer. 2008 Sep 2;99(5):781-8.PMID: 18682709 [PubMed - indexed for MEDLINE]Related articlesFree article

Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo.

Wakimoto N, Yin D, O'Kelly J, Haritunians T, Karlan B, Said J, Xing H, Koeffler HP.

Cancer Sci. 2008 Sep;99(9):1793-7. Epub 2008 Jul 10.PMID: 18627377 [PubMed - indexed for MEDLINE]Related articles

Chronic phase of ETV6-ABL1 positive CML responds to imatinib.

Kawamata N, Dashti A, Lu D, Miller B, Koeffler HP, Schreck R, Moore S, Ogawa S.

Genes Chromosomes Cancer. 2008 Oct;47(10):919-21. No abstract available. PMID: 18615681 [PubMed - indexed for MEDLINE]Related articles

Advances in the treatment of acute myeloid leukemia: from chromosomal aberrations to biologically targeted therapy.

Lübbert M, Müller-Tidow C, Hofmann WK, Koeffler HP.

J Cell Biochem. 2008 Aug 15;104(6):2059-70. Review.PMID: 18613031 [PubMed - indexed for MEDLINE]Related articles

Adaptor protein Lnk associates with Tyr(568) in c-Kit.

Gueller S, Gery S, Nowak V, Liu L, Serve H, Koeffler HP.

Biochem J. 2008 Oct 15;415(2):241-5.PMID: 18588518 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional domains of CCN1 (Cyr61) regulate breast cancer progression.

O'Kelly J, Chung A, Lemp N, Chumakova K, Yin D, Wang HJ, Said J, Gui D, Miller CW, Karlan BY, Koeffler HP.

Int J Oncol. 2008 Jul;33(1):59-67.PMID: 18575751 [PubMed - indexed for MEDLINE]Related articles

ERCC5 is a novel biomarker of ovarian cancer prognosis.

Walsh CS, Ogawa S, Karahashi H, Scoles DR, Pavelka JC, Tran H, Miller CW, Kawamata N, Ginther C, Dering J, Sanada M, Nannya Y, Slamon DJ, Koeffler HP, Karlan BY.

J Clin Oncol. 2008 Jun 20;26(18):2952-8.PMID: 18565881 [PubMed - indexed for MEDLINE]Related articles

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme.

Yin D, Wakimoto N, Xing H, Lu D, Huynh T, Wang X, Black KL, Koeffler HP.

Int J Cancer. 2008 Sep 15;123(6):1364-75.PMID: 18561312 [PubMed - indexed for MEDLINE]Related articles

A Role for the PPARgamma in Cancer Therapy.

Campbell MJ, Carlberg C, Koeffler HP.

PPAR Res. 2008;2008:314974.PMID: 18528521 [PubMed - in process]Related articlesFree article

The role of circadian regulation in cancer.

Gery S, Koeffler HP.

Cold Spring Harb Symp Quant Biol. 2007;72:459-64. Review.PMID: 18419305 [PubMed - indexed for MEDLINE]Related articles

Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells.

Haritunians T, Gueller S, Zhang L, Badr R, Yin D, Xing H, Fung MC, Koeffler HP.

Leuk Res. 2008 Sep;32(9):1366-73. Epub 2008 Apr 10.PMID: 18405967 [PubMed - indexed for MEDLINE]Related articles

MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells.

Nishioka C, Ikezoe T, Yang J, Takeuchi S, Koeffler HP, Yokoyama A.

Leuk Res. 2008 Sep;32(9):1382-92. Epub 2008 Apr 3.PMID: 18394702 [PubMed - indexed for MEDLINE]Related articles

Identification of marker genes including RUNX3 (AML2) that discriminate between different myeloproliferative neoplasms and normal individuals.

Müller CI, Luong QT, Shih LY, Jones LC, Desmond JC, Kawamata N, Tcherniantchouk O, Liu Q, Ito K, Osato M, Ito Y, Tefferi A, de Vos S, Koeffler HP.

Leukemia. 2008 Sep;22(9):1773-8. Epub 2008 Mar 6. No abstract available. PMID: 18323800 [PubMed - indexed for MEDLINE]Related articles