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    Results: 1 to 50 of 126

    2.

    Perceptions of cancer risks and predictors of colon and endometrial cancer screening in women undergoing genetic testing for Lynch syndrome.

    Hadley DW, Jenkins JF, Steinberg SM, Liewehr D, Moller S, Martin JC, Calzone KA, Soballe PW, Kirsch IR.

    J Clin Oncol. 2008 Feb 20;26(6):948-54.PMID: 18281669 [PubMed - indexed for MEDLINE]Related articles

    3.

    Predictive value of microsatellite instability-high remains controversial.

    Kim GP, Colangelo LH, Paik S, O'Connell MJ, Kirsch IR, Allegra C, Wolmark N.

    J Clin Oncol. 2007 Oct 20;25(30):4857; author reply 4857-8. No abstract available. PMID: 17947740 [PubMed - indexed for MEDLINE]Related articles

    4.

    Pubertal impairment in Nhlh2 null mice is associated with hypothalamic and pituitary deficiencies.

    Cogliati T, Delgado-Romero P, Norwitz ER, Guduric-Fuchs J, Kaiser UB, Wray S, Kirsch IR.

    Mol Endocrinol. 2007 Dec;21(12):3013-27. Epub 2007 Aug 23.PMID: 17717072 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Randomized comparison of phone versus in-person BRCA1/2 predisposition genetic test result disclosure counseling.

    Jenkins J, Calzone KA, Dimond E, Liewehr DJ, Steinberg SM, Jourkiv O, Klein P, Soballe PW, Prindiville SA, Kirsch IR.

    Genet Med. 2007 Aug;9(8):487-95.PMID: 17700386 [PubMed - indexed for MEDLINE]Related articles

    6.

    Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study.

    Kim GP, Colangelo LH, Wieand HS, Paik S, Kirsch IR, Wolmark N, Allegra CJ; National Cancer Institute.

    J Clin Oncol. 2007 Mar 1;25(7):767-72. Epub 2007 Jan 16.PMID: 17228023 [PubMed - indexed for MEDLINE]Related articles

    7.

    Gene expression patterns distinguish colonoscopically isolated human aberrant crypt foci from normal colonic mucosa.

    Glebov OK, Rodriguez LM, Soballe P, DeNobile J, Cliatt J, Nakahara K, Kirsch IR.

    Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2253-62.PMID: 17119054 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators.

    Hart JR, Glebov O, Ernst RJ, Kirsch IR, Barton JK.

    Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15359-63. Epub 2006 Oct 9.PMID: 17030786 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Linking the human cytogenetic map with nucleotide sequence: the CCAP clone set.

    Jang W, Yonescu R, Knutsen T, Brown T, Reppert T, Sirotkin K, Schuler GD, Ried T, Kirsch IR.

    Cancer Genet Cytogenet. 2006 Jul 15;168(2):89-97.PMID: 16843097 [PubMed - indexed for MEDLINE]Related articles

    10.

    Celecoxib treatment alters the gene expression profile of normal colonic mucosa.

    Glebov OK, Rodriguez LM, Lynch P, Patterson S, Lynch H, Nakahara K, Jenkins J, Cliatt J, Humbyrd CJ, Denobile J, Soballe P, Gallinger S, Buchbinder A, Gordon G, Hawk E, Kirsch IR.

    Cancer Epidemiol Biomarkers Prev. 2006 Jul;15(7):1382-91.PMID: 16835340 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Gene expression differences in normal esophageal mucosa associated with regression and progression of mild and moderate squamous dysplasia in a high-risk Chinese population.

    Joshi N, Johnson LL, Wei WQ, Abnet CC, Dong ZW, Taylor PR, Limburg PJ, Dawsey SM, Hawk ET, Qiao YL, Kirsch IR.

    Cancer Res. 2006 Jul 1;66(13):6851-60.PMID: 16818663 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Selenomethionine treatment does not alter gene expression in normal squamous esophageal mucosa in a high-risk Chinese population.

    Joshi N, Johnson LL, Wei WQ, Abnet CC, Dong ZW, Taylor PR, Limburg PJ, Dawsey SM, Hawk ET, Qiao YL, Kirsch IR.

    Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):1046-7.PMID: 16702392 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells.

    Wallqvist A, Huang R, Covell DG, Roschke AV, Gelhaus KS, Kirsch IR.

    Mol Cancer Ther. 2005 Oct;4(10):1559-68.PMID: 16227406 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes.

    Coxon A, Rozenblum E, Park YS, Joshi N, Tsurutani J, Dennis PA, Kirsch IR, Kaye FJ.

    Cancer Res. 2005 Aug 15;65(16):7137-44.PMID: 16103063 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint.

    Campaner S, Kaldis P, Izraeli S, Kirsch IR.

    Mol Cell Biol. 2005 Aug;25(15):6660-72.PMID: 16024801 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The interactive online SKY/M-FISH & CGH database and the Entrez cancer chromosomes search database: linkage of chromosomal aberrations with the genome sequence.

    Knutsen T, Gobu V, Knaus R, Padilla-Nash H, Augustus M, Strausberg RL, Kirsch IR, Sirotkin K, Ried T.

    Genes Chromosomes Cancer. 2005 Sep;44(1):52-64.PMID: 15934046 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Randomized comparison of group versus individual genetic education and counseling for familial breast and/or ovarian cancer.

    Calzone KA, Prindiville SA, Jourkiv O, Jenkins J, DeCarvalho M, Wallerstedt DB, Liewehr DJ, Steinberg SM, Soballe PW, Lipkowitz S, Klein P, Kirsch IR.

    J Clin Oncol. 2005 May 20;23(15):3455-64.PMID: 15908654 [PubMed - indexed for MEDLINE]Related articles

    18.

    A phase II and pharmacologic study of fluorouracil given by a 1-hour infusion daily for 5 days with leucovorin and interferon alpha-2a in adenocarcinoma of the large bowel.

    Ismail AS, Quinn MG, Wright MA, Ernst A, Kao V, Grogan L, Parr A, Grollman F, Kirsch IR, Grem JL.

    Oncol Rep. 2005 Jun;13(6):1145-52.PMID: 15870935 [PubMed - indexed for MEDLINE]Related articles

    19.

    Targeting cancer cells by exploiting karyotypic complexity and chromosomal instability.

    Roschke AV, Kirsch IR.

    Cell Cycle. 2005 May;4(5):679-82. Epub 2005 May 25.PMID: 15846096 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Karyotypic "state" as a potential determinant for anticancer drug discovery.

    Roschke AV, Lababidi S, Tonon G, Gehlhaus KS, Bussey K, Weinstein JN, Kirsch IR.

    Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2964-9. Epub 2005 Feb 9.PMID: 15703300 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases.

    Hahn Y, Bera TK, Gehlhaus K, Kirsch IR, Pastan IH, Lee B.

    Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13257-61. Epub 2004 Aug 23.PMID: 15326299 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Multiple reciprocal translocations in salivary gland mucoepidermoid carcinomas.

    Tonon G, Gehlhaus KS, Yonescu R, Kaye FJ, Kirsch IR.

    Cancer Genet Cytogenet. 2004 Jul 1;152(1):15-22.PMID: 15193437 [PubMed - indexed for MEDLINE]Related articles

    23.

    Sil overexpression in lung cancer characterizes tumors with increased mitotic activity.

    Erez A, Perelman M, Hewitt SM, Cojacaru G, Goldberg I, Shahar I, Yaron P, Muler I, Campaner S, Amariglio N, Rechavi G, Kirsch IR, Krupsky M, Kaminski N, Izraeli S.

    Oncogene. 2004 Jul 8;23(31):5371-7.PMID: 15107824 [PubMed - indexed for MEDLINE]Related articles

    24.

    Genetics and cytogenetics of multiple myeloma: a workshop report.

    Fonseca R, Barlogie B, Bataille R, Bastard C, Bergsagel PL, Chesi M, Davies FE, Drach J, Greipp PR, Kirsch IR, Kuehl WM, Hernandez JM, Minvielle S, Pilarski LM, Shaughnessy JD Jr, Stewart AK, Avet-Loiseau H.

    Cancer Res. 2004 Feb 15;64(4):1546-58.PMID: 14989251 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Karyotypic complexity of the NCI-60 drug-screening panel.

    Roschke AV, Tonon G, Gehlhaus KS, McTyre N, Bussey KJ, Lababidi S, Scudiero DA, Weinstein JN, Kirsch IR.

    Cancer Res. 2003 Dec 15;63(24):8634-47.PMID: 14695175 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Microsatellite instability in colon cancer.

    Allegra CJ, Kim G, Kirsch IR.

    N Engl J Med. 2003 Oct 30;349(18):1774-6; author reply 1774-6. No abstract available. PMID: 14585950 [PubMed - indexed for MEDLINE]Related articles

    27.

    Distinguishing right from left colon by the pattern of gene expression.

    Glebov OK, Rodriguez LM, Nakahara K, Jenkins J, Cliatt J, Humbyrd CJ, DeNobile J, Soballe P, Simon R, Wright G, Lynch P, Patterson S, Lynch H, Gallinger S, Buchbinder A, Gordon G, Hawk E, Kirsch IR.

    Cancer Epidemiol Biomarkers Prev. 2003 Aug;12(8):755-62.PMID: 12917207 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping.

    Reinhold WC, Kouros-Mehr H, Kohn KW, Maunakea AK, Lababidi S, Roschke A, Stover K, Alexander J, Pantazis P, Miller L, Liu E, Kirsch IR, Urasaki Y, Pommier Y, Weinstein JN.

    Cancer Res. 2003 Mar 1;63(5):1000-11.PMID: 12615715 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    A rhodium(III) complex for high-affinity DNA base-pair mismatch recognition.

    Junicke H, Hart JR, Kisko J, Glebov O, Kirsch IR, Barton JK.

    Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3737-42. Epub 2003 Feb 27.PMID: 12610209 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway.

    Tonon G, Modi S, Wu L, Kubo A, Coxon AB, Komiya T, O'Neil K, Stover K, El-Naggar A, Griffin JD, Kirsch IR, Kaye FJ.

    Nat Genet. 2003 Feb;33(2):208-13. Epub 2003 Jan 21. Erratum in: Nat Genet. 2003 Mar;33(3):430. PMID: 12539049 [PubMed - indexed for MEDLINE]Related articles

    31.

    Predisposition to arrhythmia and autonomic dysfunction in Nhlh1-deficient mice.

    Cogliati T, Good DJ, Haigney M, Delgado-Romero P, Eckhaus MA, Koch WJ, Kirsch IR.

    Mol Cell Biol. 2002 Jul;22(14):4977-83.PMID: 12077327 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability.

    Roschke AV, Stover K, Tonon G, Schäffer AA, Kirsch IR.

    Neoplasia. 2002 Jan-Feb;4(1):19-31.PMID: 11922387 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Genetic evidence that Sil is required for the Sonic Hedgehog response pathway.

    Izraeli S, Lowe LA, Bertness VL, Campaner S, Hahn H, Kirsch IR, Kuehn MR.

    Genesis. 2001 Oct;31(2):72-7.PMID: 11668681 [PubMed - indexed for MEDLINE]Related articles

    34.

    Biomarker correlations of urinary 2,4-D levels in foresters: genomic instability and endocrine disruption.

    Garry VF, Tarone RE, Kirsch IR, Abdallah JM, Lombardi DP, Long LK, Burroughs BL, Barr DB, Kesner JS.

    Environ Health Perspect. 2001 May;109(5):495-500.PMID: 11401761 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints.

    Raghavan SC, Kirsch IR, Lieber MR.

    J Biol Chem. 2001 Aug 3;276(31):29126-33. Epub 2001 Jun 4.PMID: 11390401 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Integration of cytogenetic landmarks into the draft sequence of the human genome.

    Cheung VG, Nowak N, Jang W, Kirsch IR, Zhao S, Chen XN, Furey TS, Kim UJ, Kuo WL, Olivier M, Conroy J, Kasprzyk A, Massa H, Yonescu R, Sait S, Thoreen C, Snijders A, Lemyre E, Bailey JA, Bruzel A, Burrill WD, Clegg SM, Collins S, Dhami P, Friedman C, Han CS, Herrick S, Lee J, Ligon AH, Lowry S, Morley M, Narasimhan S, Osoegawa K, Peng Z, Plajzer-Frick I, Quade BJ, Scott D, Sirotkin K, Thorpe AA, Gray JW, Hudson J, Pinkel D, Ried T, Rowen L, Shen-Ong GL, Strausberg RL, Birney E, Callen DF, Cheng JF, Cox DR, Doggett NA, Carter NP, Eichler EE, Haussler D, Korenberg JR, Morton CC, Albertson D, Schuler G, de Jong PJ, Trask BJ; BAC Resource Consortium.

    Nature. 2001 Feb 15;409(6822):953-8.PMID: 11237021 [PubMed - indexed for MEDLINE]Related articles

    37.

    A high-resolution map of human chromosome 12.

    Montgomery KT, Lee E, Miller A, Lau S, Shim C, Decker J, Chiu D, Emerling S, Sekhon M, Kim R, Lenz J, Han J, Ioshikhes I, Renault B, Marondel I, Yoon SJ, Song K, Murty VV, Scherer S, Yonescu R, Kirsch IR, Ried T, McPherson J, Gibbs R, Kucherlapati R.

    Nature. 2001 Feb 15;409(6822):945-6.PMID: 11237017 [PubMed - indexed for MEDLINE]Related articles

    38.

    A physical map of the human genome.

    McPherson JD, Marra M, Hillier L, Waterston RH, Chinwalla A, Wallis J, Sekhon M, Wylie K, Mardis ER, Wilson RK, Fulton R, Kucaba TA, Wagner-McPherson C, Barbazuk WB, Gregory SG, Humphray SJ, French L, Evans RS, Bethel G, Whittaker A, Holden JL, McCann OT, Dunham A, Soderlund C, Scott CE, Bentley DR, Schuler G, Chen HC, Jang W, Green ED, Idol JR, Maduro VV, Montgomery KT, Lee E, Miller A, Emerling S, Kucherlapati, Gibbs R, Scherer S, Gorrell JH, Sodergren E, Clerc-Blankenburg K, Tabor P, Naylor S, Garcia D, de Jong PJ, Catanese JJ, Nowak N, Osoegawa K, Qin S, Rowen L, Madan A, Dors M, Hood L, Trask B, Friedman C, Massa H, Cheung VG, Kirsch IR, Reid T, Yonescu R, Weissenbach J, Bruls T, Heilig R, Branscomb E, Olsen A, Doggett N, Cheng JF, Hawkins T, Myers RM, Shang J, Ramirez L, Schmutz J, Velasquez O, Dixon K, Stone NE, Cox DR, Haussler D, Kent WJ, Furey T, Rogic S, Kennedy S, Jones S, Rosenthal A, Wen G, Schilhabel M, Gloeckner G, Nyakatura G, Siebert R, Schlegelberger B, Korenberg J, Chen XN, Fujiyama A, Hattori M, Toyoda A, Yada T, Park HS, Sakaki Y, Shimizu N, Asakawa S, Kawasaki K, Sasaki T, Shintani A, Shimizu A, Shibuya K, Kudoh J, Minoshima S, Ramser J, Seranski P, Hoff C, Poustka A, Reinhardt R, Lehrach H; International Human Genome Mapping Consortium.

    Nature. 2001 Feb 15;409(6822):934-41.PMID: 11237014 [PubMed - indexed for MEDLINE]Related articles

    39.

    Integration of cytogenetic data with genome maps and available probes: present status and future promise.

    Kirsch IR, Ried T.

    Semin Hematol. 2000 Oct;37(4):420-8. Review.PMID: 11071363 [PubMed - indexed for MEDLINE]Related articles

    40.

    The "comparative growth assay": examining the interplay of anti-cancer agents with cells carrying single gene alterations.

    Hausner P, Venzon DJ, Grogan L, Kirsch IR.

    Neoplasia. 1999 Oct;1(4):356-67.PMID: 10935491 [PubMed - indexed for MEDLINE]Related articlesFree article

    41.

    A systematic, high-resolution linkage of the cytogenetic and physical maps of the human genome.

    Kirsch IR, Green ED, Yonescu R, Strausberg R, Carter N, Bentley D, Leversha MA, Dunham I, Braden VV, Hilgenfeld E, Schuler G, Lash AE, Shen GL, Martelli M, Kuehl WM, Klausner RD, Ried T.

    Nat Genet. 2000 Apr;24(4):339-40. No abstract available. PMID: 10742091 [PubMed - indexed for MEDLINE]Related articles

    42.

    The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene.

    Wang J, Jani-Sait SN, Escalon EA, Carroll AJ, de Jong PJ, Kirsch IR, Aplan PD.

    Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3497-502.PMID: 10737801 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    Spectral karyotyping combined with locus-specific FISH simultaneously defines genes and chromosomes involved in chromosomal translocations.

    Tonon G, Roschke A, Stover K, Shou Y, Kuehl WM, Kirsch IR.

    Genes Chromosomes Cancer. 2000 Apr;27(4):418-23.PMID: 10719373 [PubMed - indexed for MEDLINE]Related articles

    44.

    GenMapDB: a database of mapped human BAC clones.

    Morley M, Arcaro M, Burdick J, Yonescu R, Reid T, Kirsch IR, Cheung VG.

    Nucleic Acids Res. 2001 Jan 1;29(1):144-7.PMID: 11125073 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma.

    Shou Y, Martelli ML, Gabrea A, Qi Y, Brents LA, Roschke A, Dewald G, Kirsch IR, Bergsagel PL, Kuehl WM.

    Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):228-33.PMID: 10618400 [PubMed - indexed for MEDLINE]Related articlesFree article

    46.

    The SIL gene is required for mouse embryonic axial development and left-right specification.

    Izraeli S, Lowe LA, Bertness VL, Good DJ, Dorward DW, Kirsch IR, Kuehn MR.

    Nature. 1999 Jun 17;399(6737):691-4.PMID: 10385121 [PubMed - indexed for MEDLINE]Related articles

    47.

    Coordinate regulation of cyclooxygenase-2 and TGF-beta1 in replication error-positive colon cancer and azoxymethane-induced rat colonic tumors.

    Shao J, Sheng H, Aramandla R, Pereira MA, Lubet RA, Hawk E, Grogan L, Kirsch IR, Washington MK, Beauchamp RD, DuBois RN.

    Carcinogenesis. 1999 Feb;20(2):185-91.PMID: 10069452 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    Helix-loop-helix (E2-5, HEB, TAL1 and Id1) protein interaction with the TCRalphadelta enhancers.

    Bernard M, Delabesse E, Smit L, Millien C, Kirsch IR, Strominger JL, Macintyre EA.

    Int Immunol. 1998 Oct;10(10):1539-49.PMID: 9796921 [PubMed - indexed for MEDLINE]Related articlesFree article

    49.

    Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells.

    Krosl G, He G, Lefrancois M, Charron F, Roméo PH, Jolicoeur P, Kirsch IR, Nemer M, Hoang T.

    J Exp Med. 1998 Aug 3;188(3):439-50.PMID: 9687522 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Expression of the SIL gene is correlated with growth induction and cellular proliferation.

    Izraeli S, Colaizzo-Anas T, Bertness VL, Mani K, Aplan PD, Kirsch IR.

    Cell Growth Differ. 1997 Nov;8(11):1171-9.PMID: 9372240 [PubMed - indexed for MEDLINE]Related articlesFree article

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