PubMed

Sexual dimorphism in environmental epigenetic programming.

Gabory A, Attig L, Junien C.

Mol Cell Endocrinol. 2009 May 25;304(1-2):8-18. Epub 2009 Mar 9. Review.PMID: 19433243 [PubMed - indexed for MEDLINE]Related articles

The molecular basis of familial hypercholesterolemia in Lebanon: spectrum of LDLR mutations and role of PCSK9 as a modifier gene.

Abifadel M, Rabès JP, Jambart S, Halaby G, Gannagé-Yared MH, Sarkis A, Beaino G, Varret M, Salem N, Corbani S, Aydénian H, Junien C, Munnich A, Boileau C.

Hum Mutat. 2009 Jul;30(7):E682-91.PMID: 19319977 [PubMed - indexed for MEDLINE]Related articles

Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease.

Abifadel M, Rabès JP, Devillers M, Munnich A, Erlich D, Junien C, Varret M, Boileau C.

Hum Mutat. 2009 Apr;30(4):520-9. Review.PMID: 19191301 [PubMed - indexed for MEDLINE]Related articles

A simple and fast method for cell recovery and DNA content analysis from various mouse tissues by flow cytometry.

Foiry L, Mégret J, Junien C, Gourdon G.

Cytotechnology. 2006 Oct;52(2):107-12. Epub 2006 Dec 14.PMID: 19002869 [PubMed - in process]Related articles

Identification of 23 TGFBR2 and 6 TGFBR1 gene mutations and genotype-phenotype investigations in 457 patients with Marfan syndrome type I and II, Loeys-Dietz syndrome and related disorders.

Stheneur C, Collod-Béroud G, Faivre L, Gouya L, Sultan G, Le Parc JM, Moura B, Attias D, Muti C, Sznajder M, Claustres M, Junien C, Baumann C, Cormier-Daire V, Rio M, Lyonnet S, Plauchu H, Lacombe D, Chevallier B, Jondeau G, Boileau C.

Hum Mutat. 2008 Nov;29(11):E284-95.PMID: 18781618 [PubMed - indexed for MEDLINE]Related articles

Sexual dimorphism in non-Mendelian inheritance.

Vigé A, Gallou-Kabani C, Junien C.

Pediatr Res. 2008 Apr;63(4):340-7. Review.PMID: 18356736 [PubMed - indexed for MEDLINE]Related articles

Lifelong circadian and epigenetic drifts in metabolic syndrome.

Gallou-Kabani C, Vigé A, Junien C.

Epigenetics. 2007 Sep;2(3):137-46. Epub 2007 Aug 14. Review.PMID: 17965598 [PubMed - indexed for MEDLINE]Related articles

DM1 CTG expansions affect insulin receptor isoforms expression in various tissues of transgenic mice.

Guiraud-Dogan C, Huguet A, Gomes-Pereira M, Brisson E, Bassez G, Junien C, Gourdon G.

Biochim Biophys Acta. 2007 Dec;1772(11-12):1183-91. Epub 2007 Sep 15.PMID: 17950578 [PubMed - indexed for MEDLINE]Related articles

Report on the IASO Stock Conference 2006: early and lifelong environmental epigenomic programming of metabolic syndrome, obesity and type II diabetes.

Junien C, Nathanielsz P.

Obes Rev. 2007 Nov;8(6):487-502. Review.PMID: 17949354 [PubMed - indexed for MEDLINE]Related articles

C57BL/6J and A/J mice fed a high-fat diet delineate components of metabolic syndrome.

Gallou-Kabani C, Vigé A, Gross MS, Rabès JP, Boileau C, Larue-Achagiotis C, Tomé D, Jais JP, Junien C.

Obesity (Silver Spring). 2007 Aug;15(8):1996-2005.PMID: 17712117 [PubMed - indexed for MEDLINE]Related articles

Third Santorini conference pharmacogenomics workshop report: "Pharmacogenomics at the crossroads: what else than good science will be needed for the field to become part of Personalized Medicine?".

Llerena A, Michel G, Jeannesson E, Wong S, Manolopoulos VG, Hockett RD, Boubekeur K, Siest G, Beaune P, Haefliger C, Arnold HP, Junien C, Petrovic N, Molloy R, Bekers O, Donnelly C, Arens HJ, Kaput J, McComb J.

Clin Chem Lab Med. 2007;45(7):843-50.PMID: 17617025 [PubMed - indexed for MEDLINE]Related articles

CTG trinucleotide repeat "big jumps": large expansions, small mice.

Gomes-Pereira M, Foiry L, Nicole A, Huguet A, Junien C, Munnich A, Gourdon G.

PLoS Genet. 2007 Apr 6;3(4):e52. Epub 2007 Feb 22.PMID: 17411343 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond.

Gallou-Kabani C, Vigé A, Gross MS, Junien C.

Clin Chem Lab Med. 2007;45(3):321-7. Review.PMID: 17378726 [PubMed - indexed for MEDLINE]Related articles

Association between an endoglin gene polymorphism and systemic sclerosis-related pulmonary arterial hypertension.

Wipff J, Kahan A, Hachulla E, Sibilia J, Cabane J, Meyer O, Mouthon L, Guillevin L, Junien C, Boileau C, Allanore Y.

Rheumatology (Oxford). 2007 Apr;46(4):622-5. Epub 2006 Dec 13.PMID: 17166870 [PubMed - indexed for MEDLINE]Related articlesFree article

Resistance to high-fat diet in the female progeny of obese mice fed a control diet during the periconceptual, gestation, and lactation periods.

Gallou-Kabani C, Vigé A, Gross MS, Boileau C, Rabes JP, Fruchart-Najib J, Jais JP, Junien C.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1095-100. Epub 2006 Dec 12.PMID: 17164437 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of diets and nutrients/drugs on early epigenetic programming.

Junien C.

J Inherit Metab Dis. 2006 Apr-Jun;29(2-3):359-65. Review.PMID: 16763902 [PubMed - indexed for MEDLINE]Related articles

[Nutritional epigenomics of metabolic syndrome]

Junien C, Gallou-Kabani C, Vigé A, Gross MS.

Med Sci (Paris). 2005 Dec;21 Spec No:44-52. Review. French. PMID: 16598905 [PubMed - indexed for MEDLINE]Related articles

An oligonucleotide microarray for mouse imprinted genes profiling.

Vigé A, Gallou-Kabani C, Gross MS, Fabre A, Junien C, Jais JP.

Cytogenet Genome Res. 2006;113(1-4):253-61.PMID: 16575188 [PubMed - indexed for MEDLINE]Related articles

Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.

Foiry L, Dong L, Savouret C, Hubert L, te Riele H, Junien C, Gourdon G.

Hum Genet. 2006 Jun;119(5):520-6. Epub 2006 Mar 22.PMID: 16552576 [PubMed - indexed for MEDLINE]Related articles

Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas.

Niclot S, Pruvot Q, Besson C, Savoy D, Macintyre E, Salles G, Brousse N, Varet B, Landais P, Taupin P, Junien C, Baudry-Bluteau D.

Blood. 2006 Jul 1;108(1):278-85. Epub 2006 Jan 12.PMID: 16410450 [PubMed - indexed for MEDLINE]Related articlesFree article

The case for strategic international alliances to harness nutritional genomics for public and personal health.

Kaput J, Ordovas JM, Ferguson L, van Ommen B, Rodriguez RL, Allen L, Ames BN, Dawson K, German B, Krauss R, Malyj W, Archer MC, Barnes S, Bartholomew A, Birk R, van Bladeren P, Bradford KJ, Brown KH, Caetano R, Castle D, Chadwick R, Clarke S, Clément K, Cooney CA, Corella D, Manica da Cruz IB, Daniel H, Duster T, Ebbesson SO, Elliott R, Fairweather-Tait S, Felton J, Fenech M, Finley JW, Fogg-Johnson N, Gill-Garrison R, Gibney MJ, Gillies PJ, Gustafsson JA, Hartman Iv JL, He L, Hwang JK, Jais JP, Jang Y, Joost H, Junien C, Kanter M, Kibbe WA, Koletzko B, Korf BR, Kornman K, Krempin DW, Langin D, Lauren DR, Ho Lee J, Leveille GA, Lin SJ, Mathers J, Mayne M, McNabb W, Milner JA, Morgan P, Muller M, Nikolsky Y, van der Ouderaa F, Park T, Pensel N, Perez-Jimenez F, Poutanen K, Roberts M, Saris WH, Schuster G, Shelling AN, Simopoulos AP, Southon S, Tai ES, Towne B, Trayhurn P, Uauy R, Visek WJ, Warden C, Weiss R, Wiencke J, Winkler J, Wolff GL, Zhao-Wilson X, Zucker JD.

Br J Nutr. 2005 Nov;94(5):623-32. Review.PMID: 16277761 [PubMed - indexed for MEDLINE]Related articles

Novel mutations of the PCSK9 gene cause variable phenotype of autosomal dominant hypercholesterolemia.

Allard D, Amsellem S, Abifadel M, Trillard M, Devillers M, Luc G, Krempf M, Reznik Y, Girardet JP, Fredenrich A, Junien C, Varret M, Boileau C, Benlian P, Rabès JP.

Hum Mutat. 2005 Nov;26(5):497. Erratum in: Hum Mutat. 2005 Dec;26(6):592. PMID: 16211558 [PubMed - indexed for MEDLINE]Related articles

Congenital hyperinsulinism and mosaic abnormalities of the ploidy.

Giurgea I, Sanlaville D, Fournet JC, Sempoux C, Bellanné-Chantelot C, Touati G, Hubert L, Groos MS, Brunelle F, Rahier J, Henquin JC, Dunne MJ, Jaubert F, Robert JJ, Nihoul-Fékété C, Vekemans M, Junien C, de Lonlay P.

J Med Genet. 2006 Mar;43(3):248-54. Epub 2005 Jul 20.PMID: 16033916 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutritional epigenomics of metabolic syndrome: new perspective against the epidemic.

Gallou-Kabani C, Junien C.

Diabetes. 2005 Jul;54(7):1899-906. Review.PMID: 15983188 [PubMed - indexed for MEDLINE]Related articlesFree article

[Nutritionnal epigenomics: consequences of unbalanced diets on epigenetics processes of programming during lifespan and between generations]

Junien C, Gallou-Kabani C, Vigé A, Gross MS.

Ann Endocrinol (Paris). 2005 Apr;66(2 Pt 3):2S19-28. Review. French. PMID: 15959393 [PubMed - indexed for MEDLINE]Related articles

[Nutritional epigenomics of metabolic syndrome]

Junien C, Gallou-Kabani C, Vigé A, Gross MS.

Med Sci (Paris). 2005 Apr;21(4):396-404. Review. French. PMID: 15811305 [PubMed - indexed for MEDLINE]Related articles

Frequent overexpression of cyclin D2/cyclin-dependent kinase 4 in Wilms' tumor.

Faussillon M, Monnier L, Junien C, Jeanpierre C.

Cancer Lett. 2005 Apr 18;221(1):67-75.PMID: 15797629 [PubMed - indexed for MEDLINE]Related articles

Genetics of congenital hyperinsulinism.

Fournet JC, Junien C.

Endocr Pathol. 2004 Fall;15(3):233-40. Review.PMID: 15640549 [PubMed - indexed for MEDLINE]Related articles

Cancer nutrigenomics.

Junien C, Gallou C.

World Rev Nutr Diet. 2004;93:210-69. Review. No abstract available. PMID: 15496809 [PubMed - indexed for MEDLINE]Related articles

Genotype-phenotype correlation in von Hippel-Lindau families with renal lesions.

Gallou C, Chauveau D, Richard S, Joly D, Giraud S, Olschwang S, Martin N, Saquet C, Chrétien Y, Méjean A, Correas JM, Benoît G, Colombeau P, Grünfeld JP, Junien C, Béroud C.

Hum Mutat. 2004 Sep;24(3):215-24. Erratum in: Hum Mutat. 2004 Nov;24(5):435-6. PMID: 15300849 [PubMed - indexed for MEDLINE]Related articles

Heterozygous TGFBR2 mutations in Marfan syndrome.

Mizuguchi T, Collod-Beroud G, Akiyama T, Abifadel M, Harada N, Morisaki T, Allard D, Varret M, Claustres M, Morisaki H, Ihara M, Kinoshita A, Yoshiura K, Junien C, Kajii T, Jondeau G, Ohta T, Kishino T, Furukawa Y, Nakamura Y, Niikawa N, Boileau C, Matsumoto N.

Nat Genet. 2004 Aug;36(8):855-60. Epub 2004 Jul 4.PMID: 15235604 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of CTG repeats using DM1 model mice.

Savouret C, Junien C, Gourdon G.

Methods Mol Biol. 2004;277:185-97.PMID: 15201457 [PubMed - indexed for MEDLINE]Related articles

Hyperinsulinemic hypoglycemia in children.

de Lonlay P, Giurgea I, Robert JJ, Fournet JC, Touati G, Nihoul-Fékété C, Brunelle F, Jaubert F, Rahier J, Sempoux C, Junien C, Saudubray JM, Dunne M, Otonkoski T, Ribeiro M, Bellané-Chantelot C; European Group of Hyperinsulinism.

Ann Endocrinol (Paris). 2004 Feb;65(1):96-8. Review. No abstract available. PMID: 15122102 [PubMed - indexed for MEDLINE]Related articles

Identification of the first Lebanese mutation in the LPL gene and description of a rapid detection method.

Abifadel M, Jambart S, Allard D, Rabès JP, Varret M, Derré A, Chouery E, Salem N, Junien C, Aydénian H, Boileau C.

Clin Genet. 2004 Feb;65(2):158-61. No abstract available. PMID: 14984478 [PubMed - indexed for MEDLINE]Related articles

Delineation of a 2.8 megabases region harboring a potential tumor suppressor gene involved in renal cell carcinoma, that is commonly deleted from chromosome 14.

Gallou C, Méjean A, Bouvier R, Lucien F, Perennou M, Zindy PJ, Grifone R, Chrétien Y, Junien C, Béroud C.

Anticancer Res. 2003 Nov-Dec;23(6C):4865-70.PMID: 14981937 [PubMed - indexed for MEDLINE]Related articles

MSH2-dependent germinal CTG repeat expansions are produced continuously in spermatogonia from DM1 transgenic mice.

Savouret C, Garcia-Cordier C, Megret J, te Riele H, Junien C, Gourdon G.

Mol Cell Biol. 2004 Jan;24(2):629-37.PMID: 14701736 [PubMed - indexed for MEDLINE]Related articlesFree article

Silencing of CDKN1C (p57KIP2) is associated with hypomethylation at KvDMR1 in Beckwith-Wiedemann syndrome.

Diaz-Meyer N, Day CD, Khatod K, Maher ER, Cooper W, Reik W, Junien C, Graham G, Algar E, Der Kaloustian VM, Higgins MJ.

J Med Genet. 2003 Nov;40(11):797-801.PMID: 14627666 [PubMed - indexed for MEDLINE]Related articlesFree article

Update of the UMD-FBN1 mutation database and creation of an FBN1 polymorphism database.

Collod-Béroud G, Le Bourdelles S, Ades L, Ala-Kokko L, Booms P, Boxer M, Child A, Comeglio P, De Paepe A, Hyland JC, Holman K, Kaitila I, Loeys B, Matyas G, Nuytinck L, Peltonen L, Rantamaki T, Robinson P, Steinmann B, Junien C, Béroud C, Boileau C.

Hum Mutat. 2003 Sep;22(3):199-208. Review.PMID: 12938084 [PubMed - indexed for MEDLINE]Related articles

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.

Abifadel M, Varret M, Rabès JP, Allard D, Ouguerram K, Devillers M, Cruaud C, Benjannet S, Wickham L, Erlich D, Derré A, Villéger L, Farnier M, Beucler I, Bruckert E, Chambaz J, Chanu B, Lecerf JM, Luc G, Moulin P, Weissenbach J, Prat A, Krempf M, Junien C, Seidah NG, Boileau C.

Nat Genet. 2003 Jun;34(2):154-6.PMID: 12730697 [PubMed - indexed for MEDLINE]Related articles

CTG repeat instability and size variation timing in DNA repair-deficient mice.

Savouret C, Brisson E, Essers J, Kanaar R, Pastink A, te Riele H, Junien C, Gourdon G.

EMBO J. 2003 May 1;22(9):2264-73.PMID: 12727892 [PubMed - indexed for MEDLINE]Related articlesFree article

Cadherins in Wilms' tumor: E-cadherin expression despite absence of WT1.

Baudry D, Cabanis MO, Patte C, Zucker JM, Pein F, Fournet JC, Sarnacki S, Junien C, Jeanpierre C.

Anticancer Res. 2003 Jan-Feb;23(1A):475-8.PMID: 12680252 [PubMed - indexed for MEDLINE]Related articles

The focal form of persistent hyperinsulinemic hypoglycemia of infancy: morphological and molecular studies show structural and functional differences with insulinoma.

Sempoux C, Guiot Y, Dahan K, Moulin P, Stevens M, Lambot V, de Lonlay P, Fournet JC, Junien C, Jaubert F, Nihoul-Fekete C, Saudubray JM, Rahier J.

Diabetes. 2003 Mar;52(3):784-94.PMID: 12606521 [PubMed - indexed for MEDLINE]Related articlesFree article

The genetics of neonatal hyperinsulinism.

Fournet JC, Junien C.

Horm Res. 2003;59 Suppl 1:30-4. Review.PMID: 12566718 [PubMed - indexed for MEDLINE]Related articles

Facial appearance in persistent hyperinsulinemic hypoglycemia.

de Lonlay P, Cormier-Daire V, Amiel J, Touati G, Goldenberg A, Fournet JC, Brunelle F, Nihoul-Fékété C, Rahier J, Junien C, Robert JJ, Saudubray JM.

Am J Med Genet. 2002 Aug 1;111(2):130-3.PMID: 12210338 [PubMed - indexed for MEDLINE]Related articles

ABCC8 (SUR1) and KCNJ11 (KIR6.2) mutations in persistent hyperinsulinemic hypoglycemia of infancy and evaluation of different therapeutic measures.

Darendeliler F, Fournet JC, Baş F, Junien C, Gross MS, Bundak R, Saka N, Günöz H.

J Pediatr Endocrinol Metab. 2002 Jul-Aug;15(7):993-1000.PMID: 12199344 [PubMed - indexed for MEDLINE]Related articles

Changes in WT1 splicing are associated with a specific gene expression profile in Wilms' tumour.

Baudry D, Faussillon M, Cabanis MO, Rigolet M, Zucker JM, Patte C, Sarnacki S, Boccon-Gibod L, Junien C, Jeanpierre C.

Oncogene. 2002 Aug 15;21(36):5566-73.PMID: 12165855 [PubMed - indexed for MEDLINE]Related articlesFree article

The UMD-LDLR database: additions to the software and 490 new entries to the database.

Villéger L, Abifadel M, Allard D, Rabès JP, Thiart R, Kotze MJ, Béroud C, Junien C, Boileau C, Varret M.

Hum Mutat. 2002 Aug;20(2):81-7. Review.PMID: 12124988 [PubMed - indexed for MEDLINE]Related articles

Major difference in aetiology and phenotypic abnormalities between transient and permanent neonatal diabetes.

Marquis E, Robert JJ, Bouvattier C, Bellanné-Chantelot C, Junien C, Diatloff-Zito C.

J Med Genet. 2002 May;39(5):370-4. Review. No abstract available. PMID: 12011161 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. A series of 175 cases.

de Lonlay P, Fournet JC, Touati G, Groos MS, Martin D, Sevin C, Delagne V, Mayaud C, Chigot V, Sempoux C, Brusset MC, Laborde K, Bellane-Chantelot C, Vassault A, Rahier J, Junien C, Brunelle F, Nihoul-Fékété C, Saudubray JM, Robert JJ.

Eur J Pediatr. 2002 Jan;161(1):37-48. Review.PMID: 11808879 [PubMed - indexed for MEDLINE]Related articles

Profiling of differential gene expression in Wilms tumor by cDNA expression array.

Rigolet M, Faussillon M, Baudry D, Junien C, Jeanpierre C.

Pediatr Nephrol. 2001 Dec;16(12):1113-21.PMID: 11793111 [PubMed - indexed for MEDLINE]Related articles