PubMed

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3).

Beurel E, Michalek SM, Jope RS.

Trends Immunol. 2009 Oct 14. [Epub ahead of print]PMID: 19836308 [PubMed - as supplied by publisher]Related articles

Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of Fragile X syndrome.

Yuskaitis CJ, Mines MA, King MK, Sweatt JD, Miller CA, Jope RS.

Biochem Pharmacol. 2009 Sep 30. [Epub ahead of print]PMID: 19799873 [PubMed - as supplied by publisher]Related articles

XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3.

Sun M, Meares G, Song L, Jope RS.

Cell Signal. 2009 Dec;21(12):1857-65. Epub 2009 Aug 19.PMID: 19698783 [PubMed - in process]Related articles

Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3alpha/beta impairs in vivo neural precursor cell proliferation.

Eom TY, Jope RS.

Biol Psychiatry. 2009 Sep 1;66(5):494-502. Epub 2009 Jun 11.PMID: 19520363 [PubMed - indexed for MEDLINE]Related articles

Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain.

Beurel E, Jope RS.

J Neuroinflammation. 2009 Mar 11;6:9.PMID: 19284588 [PubMed - indexed for MEDLINE]Related articlesFree article

GSK3 beta N-terminus binding to p53 promotes its acetylation.

Eom TY, Jope RS.

Mol Cancer. 2009 Mar 5;8:14.PMID: 19265551 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells.

Beurel E, Jope RS.

Cell Signal. 2009 Jun;21(6):978-85. Epub 2009 Mar 1.PMID: 19258035 [PubMed - indexed for MEDLINE]Related articles

Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity.

Yuskaitis CJ, Jope RS.

Cell Signal. 2009 Feb;21(2):264-73. Epub 2008 Oct 29.PMID: 19007880 [PubMed - indexed for MEDLINE]Related articles

Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.

Min WW, Yuskaitis CJ, Yan Q, Sikorski C, Chen S, Jope RS, Bauchwitz RP.

Neuropharmacology. 2009 Feb;56(2):463-72. Epub 2008 Oct 14.PMID: 18952114 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of an antiapoptotic protein complex at death receptors.

Sun M, Song L, Li Y, Zhou T, Jope RS.

Cell Death Differ. 2008 Dec;15(12):1887-900. Epub 2008 Oct 10.PMID: 18846110 [PubMed - indexed for MEDLINE]Related articlesFree article

Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation.

Polter A, Yang S, Zmijewska AA, van Groen T, Paik JH, Depinho RA, Peng SL, Jope RS, Li X.

Biol Psychiatry. 2009 Jan 15;65(2):150-9. Epub 2008 Sep 27.PMID: 18823877 [PubMed - indexed for MEDLINE]Related articles

Lithium prevents and ameliorates experimental autoimmune encephalomyelitis.

De Sarno P, Axtell RC, Raman C, Roth KA, Alessi DR, Jope RS.

J Immunol. 2008 Jul 1;181(1):338-45.PMID: 18566399 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of STAT family members by glycogen synthase kinase-3.

Beurel E, Jope RS.

J Biol Chem. 2008 Aug 8;283(32):21934-44. Epub 2008 Jun 11.PMID: 18550525 [PubMed - indexed for MEDLINE]Related articlesFree article

HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation.

Meares GP, Zmijewska AA, Jope RS.

Cell Signal. 2008 Feb;20(2):347-58. Epub 2007 Nov 17.PMID: 18083346 [PubMed - indexed for MEDLINE]Related articlesFree article

Neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3.

Eom TY, Roth KA, Jope RS.

J Biol Chem. 2007 Aug 3;282(31):22856-64. Epub 2007 Jun 4.PMID: 17548347 [PubMed - indexed for MEDLINE]Related articlesFree article

Resolution of the nuclear localization mechanism of glycogen synthase kinase-3: functional effects in apoptosis.

Meares GP, Jope RS.

J Biol Chem. 2007 Jun 8;282(23):16989-7001. Epub 2007 Apr 16.PMID: 17438332 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death.

Mookherjee P, Quintanilla R, Roh MS, Zmijewska AA, Jope RS, Johnson GV.

J Cell Biochem. 2007 Sep 1;102(1):196-210.PMID: 17340627 [PubMed - indexed for MEDLINE]Related articlesFree article

Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency.

Clodfelder-Miller BJ, Zmijewska AA, Johnson GV, Jope RS.

Diabetes. 2006 Dec;55(12):3320-5.PMID: 17130475 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions.

Jope RS, Roh MS.

Curr Drug Targets. 2006 Nov;7(11):1421-34. Review.PMID: 17100582 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics.

Jope RS, Yuskaitis CJ, Beurel E.

Neurochem Res. 2007 Apr-May;32(4-5):577-95. Epub 2006 Aug 30. Review.PMID: 16944320 [PubMed - indexed for MEDLINE]Related articlesFree article

The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.

Beurel E, Jope RS.

Prog Neurobiol. 2006 Jul;79(4):173-89. Epub 2006 Aug 28. Review.PMID: 16935409 [PubMed - indexed for MEDLINE]Related articlesFree article

Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder.

Li X, Friedman AB, Zhu W, Wang L, Boswell S, May RS, Davis LL, Jope RS.

Biol Psychiatry. 2007 Jan 15;61(2):216-22. Epub 2006 Jun 27. Erratum in: Biol Psychiatry. 2007 Jan 15;61(2):261. PMID: 16806104 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular stress increases RGS2 mRNA and decreases RGS4 mRNA levels in SH-SY5Y cells.

Song L, Jope RS.

Neurosci Lett. 2006 Jul 24;402(3):205-9. Epub 2006 Jun 2.PMID: 16733081 [PubMed - indexed for MEDLINE]Related articlesFree article

AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.

King TD, Song L, Jope RS.

Biochem Pharmacol. 2006 May 28;71(11):1637-47. Epub 2006 Mar 10.PMID: 16620785 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors.

De Sarno P, Bijur GN, Zmijewska AA, Li X, Jope RS.

Neurobiol Aging. 2006 Mar;27(3):413-22. Epub 2005 Apr 26.PMID: 16464655 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiological and pathological changes in glucose regulate brain Akt and glycogen synthase kinase-3.

Clodfelder-Miller B, De Sarno P, Zmijewska AA, Song L, Jope RS.

J Biol Chem. 2005 Dec 2;280(48):39723-31. Epub 2005 Sep 22.PMID: 16179343 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

Martin M, Rehani K, Jope RS, Michalek SM.

Nat Immunol. 2005 Aug;6(8):777-84. Epub 2005 Jul 10.PMID: 16007092 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress.

King TD, Jope RS.

Neuroreport. 2005 Apr 25;16(6):597-601.PMID: 15812315 [PubMed - indexed for MEDLINE]Related articles

Anti-apoptotic effects of muscarinic receptor activation are mediated by Rho kinase.

De Sarno P, Shestopal SA, Zmijewska AA, Jope RS.

Brain Res. 2005 Apr 11;1041(1):112-5.PMID: 15804506 [PubMed - indexed for MEDLINE]Related articles

Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine.

Roh MS, Eom TY, Zmijewska AA, De Sarno P, Roth KA, Jope RS.

Biol Psychiatry. 2005 Feb 1;57(3):278-86.PMID: 15691529 [PubMed - indexed for MEDLINE]Related articles

Anesthesia and post-mortem interval profoundly influence the regulatory serine phosphorylation of glycogen synthase kinase-3 in mouse brain.

Li X, Friedman AB, Roh MS, Jope RS.

J Neurochem. 2005 Feb;92(3):701-4.PMID: 15659239 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts.

Zmijewski JW, Jope RS.

Aging Cell. 2004 Oct;3(5):309-17.PMID: 15379854 [PubMed - indexed for MEDLINE]Related articlesFree article

Heat shock protein-90 dampens and directs signaling stimulated by insulin-like growth factor-1 and insulin.

Meares GP, Zmijewska AA, Jope RS.

FEBS Lett. 2004 Sep 10;574(1-3):181-6.PMID: 15358562 [PubMed - indexed for MEDLINE]Related articlesFree article

Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor.

Song L, Zhou T, Jope RS.

BMC Neurosci. 2004 May 24;5:20.PMID: 15157283 [PubMed - indexed for MEDLINE]Related articlesFree article

The glamour and gloom of glycogen synthase kinase-3.

Jope RS, Johnson GV.

Trends Biochem Sci. 2004 Feb;29(2):95-102. Review.PMID: 15102436 [PubMed - indexed for MEDLINE]Related articles

In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain.

Li X, Zhu W, Roh MS, Friedman AB, Rosborough K, Jope RS.

Neuropsychopharmacology. 2004 Aug;29(8):1426-31.PMID: 15039769 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation.

Bijur GN, Jope RS.

J Neurochem. 2003 Dec;87(6):1427-35.PMID: 14713298 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogen synthase kinase-3 beta is highly activated in nuclei and mitochondria.

Bijur GN, Jope RS.

Neuroreport. 2003 Dec 19;14(18):2415-9.PMID: 14663202 [PubMed - indexed for MEDLINE]Related articles

Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53.

Watcharasit P, Bijur GN, Song L, Zhu J, Chen X, Jope RS.

J Biol Chem. 2003 Dec 5;278(49):48872-9. Epub 2003 Sep 30.PMID: 14523002 [PubMed - indexed for MEDLINE]Related articlesFree article

Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes.

Jope RS.

Trends Pharmacol Sci. 2003 Sep;24(9):441-3. Review.PMID: 12967765 [PubMed - indexed for MEDLINE]Related articles

Should tobacco ban rule out governments too?

Jope RS.

Nature. 2003 Apr 24;422(6934):802. No abstract available. PMID: 12712167 [PubMed - indexed for MEDLINE]Related articles

Muscarinic receptor activation protects cells from apoptotic effects of DNA damage, oxidative stress, and mitochondrial inhibition.

De Sarno P, Shestopal SA, King TD, Zmijewska A, Song L, Jope RS.

J Biol Chem. 2003 Mar 28;278(13):11086-93. Epub 2003 Jan 21.PMID: 12538580 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium.

De Sarno P, Li X, Jope RS.

Neuropharmacology. 2002 Dec;43(7):1158-64.PMID: 12504922 [PubMed - indexed for MEDLINE]Related articles

Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation.

Song L, De Sarno P, Jope RS.

J Biol Chem. 2002 Nov 22;277(47):44701-8. Epub 2002 Sep 12.PMID: 12228224 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholinergic muscarinic receptor signaling by the phosphoinositide signal transduction system in Alzheimer's disease.

Jope RS.

J Alzheimers Dis. 1999 Nov;1(4-5):231-47.PMID: 12214122 [PubMed]Related articles

BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents.

Mai L, Jope RS, Li X.

J Neurochem. 2002 Jul;82(1):75-83.PMID: 12091467 [PubMed - indexed for MEDLINE]Related articles

Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection.

Li X, Bijur GN, Jope RS.

Bipolar Disord. 2002 Apr;4(2):137-44. Review.PMID: 12071511 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage.

Watcharasit P, Bijur GN, Zmijewski JW, Song L, Zmijewska A, Chen X, Johnson GV, Jope RS.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7951-5. Epub 2002 Jun 4.PMID: 12048243 [PubMed - indexed for MEDLINE]Related articlesFree article

Mood stabilizers, glycogen synthase kinase-3beta and cell survival.

Jope RS, Bijur GN.

Mol Psychiatry. 2002;7 Suppl 1:S35-45. Review.PMID: 11986994 [PubMed - indexed for MEDLINE]Related articlesFree article

Second messengers regulate RGS2 expression which is targeted to the nucleus.

Zmijewski JW, Song L, Harkins L, Cobbs CS, Jope RS.

Biochim Biophys Acta. 2001 Dec 19;1541(3):201-11.PMID: 11755214 [PubMed - indexed for MEDLINE]Related articles