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2004 | 2 |
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Page 1
Selective, orally active gamma-aminobutyric acidA alpha5 receptor inverse agonists as cognition enhancers.
J Med Chem. 2004 Apr 22;47(9):2176-9. doi: 10.1021/jm031076j.
J Med Chem. 2004.
PMID: 15084116
Identification of potent, highly constrained CGRP receptor antagonists.
Stump CA, Bell IM, Bednar RA, Fay JF, Gallicchio SN, Hershey JC, Jelley R, Kreatsoulas C, Moore EL, Mosser SD, Quigley AG, Roller SA, Salvatore CA, Sharik SS, Theberge CR, Zartman CB, Kane SA, Graham SL, Selnick HG, Vacca JP, Williams TM.
Stump CA, et al. Among authors: jelley r.
Bioorg Med Chem Lett. 2010 Apr 15;20(8):2572-6. doi: 10.1016/j.bmcl.2010.02.086. Epub 2010 Feb 25.
Bioorg Med Chem Lett. 2010.
PMID: 20299218
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3-Substituted gem-cyclohexane sulfone based gamma-secretase inhibitors for Alzheimer's disease: conformational analysis and biological activity.
Jelley RA, Elliott J, Gibson KR, Harrison T, Beher D, Clarke EE, Lewis HD, Shearman M, Wrigley JD.
Jelley RA, et al.
Bioorg Med Chem Lett. 2006 Jul 15;16(14):3839-42. doi: 10.1016/j.bmcl.2006.04.019. Epub 2006 May 6.
Bioorg Med Chem Lett. 2006.
PMID: 16682202
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Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring.
Gibson KR, Hitzel L, Mortishire-Smith RJ, Gerhard U, Jelley RA, Reeve AJ, Rowley M, Nadin A, Owens AP.
Gibson KR, et al. Among authors: jelley ra.
J Org Chem. 2002 Dec 27;67(26):9354-60. doi: 10.1021/jo026411a.
J Org Chem. 2002.
PMID: 12492338
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Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site.
Street LJ, Sternfeld F, Jelley RA, Reeve AJ, Carling RW, Moore KW, McKernan RM, Sohal B, Cook S, Pike A, Dawson GR, Bromidge FA, Wafford KA, Seabrook GR, Thompson SA, Marshall G, Pillai GV, Castro JL, Atack JR, MacLeod AM.
Street LJ, et al. Among authors: jelley ra.
J Med Chem. 2004 Jul 1;47(14):3642-57. doi: 10.1021/jm0407613.
J Med Chem. 2004.
PMID: 15214791
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NK1 antagonists based on seven membered lactam scaffolds.
Elliott JM, Carlson EJ, Chicchi GG, Dirat O, Dominguez M, Gerhard U, Jelley R, Jones AB, Kurtz MM, Tsao Kl, Wheeldon A.
Elliott JM, et al. Among authors: jelley r.
Bioorg Med Chem Lett. 2006 Jun 1;16(11):2929-32. doi: 10.1016/j.bmcl.2006.02.080. Epub 2006 Mar 29.
Bioorg Med Chem Lett. 2006.
PMID: 16574413
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