PubMed

Bioactive rather than total IGF-I is involved in acute responses to nutritional interventions in CAPD patients.

Brugts MP, Tjiong HL, Rietveld T, Wattimena JL, van den Berg JW, Fieren MW, Janssen JA.

Nephrol Dial Transplant. 2009 Nov 9. [Epub ahead of print]PMID: 19903658 [PubMed - as supplied by publisher]Related articles

Heterophilic antibodies may be a cause of falsely low total IGF1 levels.

Brugts MP, Luermans JG, Lentjes EG, van Trooyen-van Vrouwerff NJ, van der Horst FA, Slee PH, Lamberts SW, Janssen JA.

Eur J Endocrinol. 2009 Oct;161(4):561-5. Epub 2009 Jul 16.PMID: 19608715 [PubMed - indexed for MEDLINE]Related articles

Effects of type I interferons on IGF-mediated autocrine/paracrine growth of human neuroendocrine tumor cells.

Vitale G, van Koetsveld PM, de Herder WW, van der Wansem K, Janssen JA, Colao A, Lombardi G, Lamberts SW, Hofland LJ.

Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E559-66. Epub 2009 Jan 13.PMID: 19141687 [PubMed - indexed for MEDLINE]Related articles

Combined treatment for acromegaly with long-acting somatostatin analogs and pegvisomant: long-term safety for up to 4.5 years (median 2.2 years) of follow-up in 86 patients.

Neggers SJ, de Herder WW, Janssen JA, Feelders RA, van der Lely AJ.

Eur J Endocrinol. 2009 Apr;160(4):529-33. Epub 2009 Jan 13.PMID: 19141604 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies.

Roddam AW, Allen NE, Appleby P, Key TJ, Ferrucci L, Carter HB, Metter EJ, Chen C, Weiss NS, Fitzpatrick A, Hsing AW, Lacey JV Jr, Helzlsouer K, Rinaldi S, Riboli E, Kaaks R, Janssen JA, Wildhagen MF, Schröder FH, Platz EA, Pollak M, Giovannucci E, Schaefer C, Quesenberry CP Jr, Vogelman JH, Severi G, English DR, Giles GG, Stattin P, Hallmans G, Johansson M, Chan JM, Gann P, Oliver SE, Holly JM, Donovan J, Meyer F, Bairati I, Galan P.

Ann Intern Med. 2008 Oct 7;149(7):461-71, W83-8.PMID: 18838726 [PubMed - indexed for MEDLINE]Related articlesFree article

Quality of life in acromegalic patients during long-term somatostatin analog treatment with and without pegvisomant.

Neggers SJ, van Aken MO, de Herder WW, Feelders RA, Janssen JA, Badia X, Webb SM, van der Lely AJ.

J Clin Endocrinol Metab. 2008 Oct;93(10):3853-9. Epub 2008 Jul 22.PMID: 18647806 [PubMed - indexed for MEDLINE]Related articlesFree article

Advantages and disadvantages of GH/IGF-I combination treatment.

Janssen JA.

Rev Endocr Metab Disord. 2009 Jun;10(2):157-62. Epub 2008 Jul 6. Review.PMID: 18604645 [PubMed - indexed for MEDLINE]Related articles

Low circulating insulin-like growth factor I bioactivity in elderly men is associated with increased mortality.

Brugts MP, van den Beld AW, Hofland LJ, van der Wansem K, van Koetsveld PM, Frystyk J, Lamberts SW, Janssen JA.

J Clin Endocrinol Metab. 2008 Jul;93(7):2515-22. Epub 2008 Apr 15.PMID: 18413430 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal values of circulating insulin-like growth factor-I bioactivity in the healthy population: comparison with five widely used IGF-I immunoassays.

Brugts MP, Ranke MB, Hofland LJ, van der Wansem K, Weber K, Frystyk J, Lamberts SW, Janssen JA.

J Clin Endocrinol Metab. 2008 Jul;93(7):2539-45. Epub 2008 Apr 8.PMID: 18397983 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term efficacy and safety of combined treatment of somatostatin analogs and pegvisomant in acromegaly.

Neggers SJ, van Aken MO, Janssen JA, Feelders RA, de Herder WW, van der Lely AJ.

J Clin Endocrinol Metab. 2007 Dec;92(12):4598-601. Epub 2007 Sep 25.PMID: 17895318 [PubMed - indexed for MEDLINE]Related articlesFree article

Disaster response in Illinois: the role for dentists and dental hygienists.

Janssen JA, Lampiris LN.

Dent Clin North Am. 2007 Oct;51(4):779-84, v.PMID: 17888756 [PubMed - indexed for MEDLINE]Related articles

Intravenous glucose administration in fasting rats has differential effects on acylated and unacylated ghrelin in the portal and systemic circulation: a comparison between portal and peripheral concentrations in anesthetized rats.

Gauna C, Uitterlinden P, Kramer P, Kiewiet RM, Janssen JA, Delhanty PJ, van Aken MO, Ghigo E, Hofland LJ, Themmen AP, van der Lely AJ.

Endocrinology. 2007 Nov;148(11):5278-87. Epub 2007 Aug 2.PMID: 17673520 [PubMed - indexed for MEDLINE]Related articlesFree article

Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions.

Gauna C, Kiewiet RM, Janssen JA, van de Zande B, Delhanty PJ, Ghigo E, Hofland LJ, Themmen AP, van der Lely AJ.

Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E697-704. Epub 2007 Jun 19.PMID: 17578884 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-1 CA repeat variant and breast cancer risk in postmenopausal women.

González-Zuloeta Ladd AM, Liu F, Houben MP, Arias Vásquez A, Siemes C, Janssens AC, Coebergh JW, Hofman A, Janssen JA, Stricker BH, van Duijn CM.

Eur J Cancer. 2007 Jul;43(11):1718-22. Epub 2007 Jun 11.PMID: 17561390 [PubMed - indexed for MEDLINE]Related articles

Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes.

Yazdanpanah M, Aulchenko YS, Hofman A, Janssen JA, Sayed-Tabatabaei FA, van Schaik RH, Klungel OH, Stricker BH, Pols HA, Witteman JC, Lamberts SW, Oostra BA, van Duijn CM.

Diabetes. 2007 Jul;56(7):1905-12. Epub 2007 Apr 19.PMID: 17446534 [PubMed - indexed for MEDLINE]Related articlesFree article

The Asp727Glu polymorphism in the TSH receptor is associated with insulin resistance in healthy elderly men.

Peeters RP, van der Deure WM, van den Beld AW, van Toor H, Lamberts SW, Janssen JA, Uitterlinden AG, Visser TJ.

Clin Endocrinol (Oxf). 2007 Jun;66(6):808-15. Epub 2007 Apr 4.PMID: 17408423 [PubMed - indexed for MEDLINE]Related articles

An IGF-I gene polymorphism modifies the risk of developing persistent microalbuminuria in type 1 diabetes.

Hovind P, Lamberts S, Hop W, Deinum J, Tarnow L, Parving HH, Janssen JA.

Eur J Endocrinol. 2007 Jan;156(1):83-90.PMID: 17218729 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-I gene promoter polymorphism is a predictor of survival after myocardial infarction in patients with type 2 diabetes.

Yazdanpanah M, Sayed-Tabatabaei FA, Janssen JA, Rietveld I, Hofman A, Stijnen T, Pols HA, Lamberts SW, Witteman JC, van Duijn CM.

Eur J Endocrinol. 2006 Nov;155(5):751-6.PMID: 17062892 [PubMed - indexed for MEDLINE]Related articlesFree article

The alpha-adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes.

Yazdanpanah M, Sayed-Tabatabaei FA, Hofman A, Aulchenko YS, Oostra BA, Stricker BH, Pols HA, Lamberts SW, Witteman JC, Janssen JA, van Duijn CM.

Diabetes. 2006 Oct;55(10):2922-7.PMID: 17003363 [PubMed - indexed for MEDLINE]Related articlesFree article

An igf-I gene polymorphism modifies the risk of diabetic retinopathy.

Rietveld I, Ikram MK, Vingerling JR, Hofman A, Pols HA, Lamberts SW, de Jong PT, van Duijn CM, Janssen JA.

Diabetes. 2006 Aug;55(8):2387-91.PMID: 16873705 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term administration of an angiotensin-receptor antagonist in patients with impaired fasting glucose improves insulin sensitivity and increases free IGF-I.

Zandbergen AA, Lamberts SW, Janssen JA, Bootsma AH.

Eur J Endocrinol. 2006 Aug;155(2):293-6.PMID: 16868143 [PubMed - indexed for MEDLINE]Related articlesFree article

Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.

Gauna C, Delhanty PJ, van Aken MO, Janssen JA, Themmen AP, Hofland LJ, Culler M, Broglio F, Ghigo E, van der Lely AJ.

Mol Cell Endocrinol. 2006 Jun 7;251(1-2):103-11. Epub 2006 Apr 27.PMID: 16647196 [PubMed - indexed for MEDLINE]Related articles

An insulin-like growth factor-I gene polymorphism modifies the risk of microalbuminuria in subjects with an abnormal glucose tolerance.

Rietveld I, Hofman A, Pols HA, van Duijn CM, Lamberts SW, Janssen JA.

Eur J Endocrinol. 2006 May;154(5):715-21.PMID: 16645019 [PubMed - indexed for MEDLINE]Related articlesFree article

An insulin-like growth factor-I promoter polymorphism is associated with increased mortality in subjects with myocardial infarction in an elderly Caucasian population.

Yazdanpanah M, Rietveld I, Janssen JA, Njajou OT, Hofman A, Stijnen T, Pols HA, Lamberts SW, Witteman JC, van Duijn CM.

Am J Cardiol. 2006 May 1;97(9):1274-6. Epub 2006 Mar 10.PMID: 16635594 [PubMed - indexed for MEDLINE]Related articles

Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam study.

Ikram MK, Janssen JA, Roos AM, Rietveld I, Witteman JC, Breteler MM, Hofman A, van Duijn CM, de Jong PT.

Diabetes. 2006 Feb;55(2):506-10.PMID: 16443787 [PubMed - indexed for MEDLINE]Related articlesFree article

The IGF-I system and the renal and haemodynamic effects of losartan in normotensive patients with type 2 diabetes mellitus: a randomized clinical trial.

Zandbergen AA, Lamberts SW, Baggen MG, Janssen JA, Boersma E, Bootsma AH.

Clin Endocrinol (Oxf). 2006 Feb;64(2):203-8.PMID: 16430721 [PubMed - indexed for MEDLINE]Related articles

Improving the oral health of Alaska natives.

Campbell D, Pollick HF, Lituri KM, Horowitz AM, Brown J, Janssen JA, Yoder K, Garcia RI, Deinard A, Hemphill S, de la Torre MA, Shrestha B, Vargas CM.

Am J Public Health. 2005 Nov;95(11):1880; author reply 1881. Epub 2005 Sep 29. No abstract available. PMID: 16195503 [PubMed - indexed for MEDLINE]Related articlesFree article

Postoperative evaluation of patients with acromegaly: clinical significance and timing of oral glucose tolerance testing and measurement of (free) insulin-like growth factor I, acid-labile subunit, and growth hormone-binding protein levels.

Feelders RA, Bidlingmaier M, Strasburger CJ, Janssen JA, Uitterlinden P, Hofland LJ, Lamberts SW, van der Lely AJ, de Herder WW.

J Clin Endocrinol Metab. 2005 Dec;90(12):6480-9. Epub 2005 Sep 13.PMID: 16159936 [PubMed - indexed for MEDLINE]Related articlesFree article

Limited predictive value of an acute test with subcutaneous octreotide for long-term IGF-I normalization with Sandostatin LAR in acromegaly.

de Herder WW, Taal HR, Uitterlinden P, Feelders RA, Janssen JA, van der Lely AJ.

Eur J Endocrinol. 2005 Jul;153(1):67-71.PMID: 15994747 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined therapy with somatostatin analogues and weekly pegvisomant in active acromegaly.

Feenstra J, de Herder WW, ten Have SM, van den Beld AW, Feelders RA, Janssen JA, van der Lely AJ.

Lancet. 2005 May 7-13;365(9471):1644-6. Erratum in: Lancet. 2005 May;365(9471):1620. PMID: 15885297 [PubMed - indexed for MEDLINE]Related articles

The 'bio-assay' quality of life might be a better marker of disease activity in acromegalic patients than serum total IGF-I concentrations.

Bonapart IE, van Domburg R, ten Have SM, de Herder WW, Erdman RA, Janssen JA, van der Lely AJ.

Eur J Endocrinol. 2005 Feb;152(2):217-24.PMID: 15745929 [PubMed - indexed for MEDLINE]Related articlesFree article

A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters.

Peeters RP, van den Beld AW, Attalki H, Toor H, de Rijke YB, Kuiper GG, Lamberts SW, Janssen JA, Uitterlinden AG, Visser TJ.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E75-81. Epub 2005 Feb 22.PMID: 15727947 [PubMed - indexed for MEDLINE]Related articlesFree article

A promoter polymorphism of the insulin-like growth factor-I gene is associated with left ventricular hypertrophy.

Bleumink GS, Schut AF, Sturkenboom MC, Janssen JA, Witteman JC, van Duijn CM, Hofman A, Stricker BH.

Heart. 2005 Feb;91(2):239-40. No abstract available. PMID: 15657251 [PubMed - indexed for MEDLINE]Related articlesFree article

Igf-I and longevity.

Janssen JA, Lamberts SW.

Horm Res. 2004;62 Suppl 3:104-9. Review.PMID: 15539808 [PubMed - indexed for MEDLINE]Related articles

Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes.

Gauna C, Delhanty PJ, Hofland LJ, Janssen JA, Broglio F, Ross RJ, Ghigo E, van der Lely AJ.

J Clin Endocrinol Metab. 2005 Feb;90(2):1055-60. Epub 2004 Nov 9.PMID: 15536157 [PubMed - indexed for MEDLINE]Related articlesFree article

There are no acute cardiac effects of a single iv dose of human ghrelin in severe growth hormone deficient patients.

Janssen JA, Poldermans D, Hofland LJ, Vourvouri EC, Muller AF, Bax JJ, Deghenghi R, Broglio F, Ghigo E, van der Lely AJ.

J Endocrinol Invest. 2004 Jul-Aug;27(7):659-64.PMID: 15505990 [PubMed - indexed for MEDLINE]Related articles

A polymorphism in type I deiodinase is associated with circulating free insulin-like growth factor I levels and body composition in humans.

Peeters RP, van den Beld AW, van Toor H, Uitterlinden AG, Janssen JA, Lamberts SW, Visser TJ.

J Clin Endocrinol Metab. 2005 Jan;90(1):256-63. Epub 2004 Oct 13.PMID: 15483075 [PubMed - indexed for MEDLINE]Related articlesFree article

[Still no indications that the treatment of growth hormone deficient adults with growth hormones is unsafe]

Janssen JA, Visser WE, van der Lely AJ.

Ned Tijdschr Geneeskd. 2004 Jul 24;148(30):1486-9. Review. Dutch. PMID: 15481571 [PubMed - indexed for MEDLINE]Related articles

Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity.

Gauna C, Meyler FM, Janssen JA, Delhanty PJ, Abribat T, van Koetsveld P, Hofland LJ, Broglio F, Ghigo E, van der Lely AJ.

J Clin Endocrinol Metab. 2004 Oct;89(10):5035-42.PMID: 15472202 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating free insulin-like growth factor (IGF)-I, total IGF-I, and IGF binding protein-3 levels do not predict the future risk to develop prostate cancer: results of a case-control study involving 201 patients within a population-based screening with a 4-year interval.

Janssen JA, Wildhagen MF, Ito K, Blijenberg BG, Van Schaik RH, Roobol MJ, Pols HA, Lamberts SW, Schröder FH.

J Clin Endocrinol Metab. 2004 Sep;89(9):4391-6.PMID: 15356036 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival and C-reactive protein levels in elderly men.

van Rossum EF, Feelders RA, van den Beld AW, Uitterlinden AG, Janssen JA, Ester W, Brinkmann AO, Grobbee DE, de Jong FH, Pols HA, Koper JW, Lamberts SW.

Am J Med. 2004 Aug 1;117(3):158-62.PMID: 15276593 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study).

Bleumink GS, Rietveld I, Janssen JA, van Rossum EF, Deckers JW, Hofman A, Witteman JC, van Duijn CM, Stricker BH.

Am J Cardiol. 2004 Aug 1;94(3):384-6.PMID: 15276114 [PubMed - indexed for MEDLINE]Related articles

A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height.

Rietveld I, Janssen JA, van Rossum EF, Houwing-Duistermaat JJ, Rivadeneira F, Hofman A, Pols HA, van Duijn CM, Lamberts SW.

Clin Endocrinol (Oxf). 2004 Aug;61(2):195-203.PMID: 15272914 [PubMed - indexed for MEDLINE]Related articles

Is there a role of ghrelin in preventing catabolism?

Janssen JA, van der Lely AJ, Lamberts SW.

J Endocrinol Invest. 2004 Apr;27(4):400-3. Review.PMID: 15233563 [PubMed - indexed for MEDLINE]Related articles

The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study.

Rivadeneira F, Houwing-Duistermaat JJ, Beck TJ, Janssen JA, Hofman A, Pols HA, Van Duijn CM, Uitterlinden AG.

J Bone Miner Res. 2004 Aug;19(8):1280-90. Epub 2004 Apr 12.PMID: 15231015 [PubMed - indexed for MEDLINE]Related articles

Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index.

van Rossum EF, Koper JW, van den Beld AW, Uitterlinden AG, Arp P, Ester W, Janssen JA, Brinkmann AO, de Jong FH, Grobbee DE, Pols HA, Lamberts SW.

Clin Endocrinol (Oxf). 2003 Nov;59(5):585-92.PMID: 14616881 [PubMed - indexed for MEDLINE]Related articles

Circulating free insulin-like growth-factor-I (IGF-I) levels should also be measured to estimate the IGF-I bioactivity.

Janssen JA, van der Lely AJ, Lamberts SW.

J Endocrinol Invest. 2003 Jun;26(6):588-94. Review.PMID: 12952376 [PubMed - indexed for MEDLINE]Related articles

A polymorphic CA repeat in the promoter region of the insulin-like growth factor-I (IGF-I) gene.

Rietveld I, Janssen JA, Van Duijn CM, Lamberts SW.

Eur J Epidemiol. 2003;18(3):191-3. No abstract available. PMID: 12800942 [PubMed - in process]Related articles

Polymorphism in the promoter region of the insulin-like growth factor I gene is related to carotid intima-media thickness and aortic pulse wave velocity in subjects with hypertension.

Schut AF, Janssen JA, Deinum J, Vergeer JM, Hofman A, Lamberts SW, Oostra BA, Pols HA, Witteman JC, van Duijn CM.

Stroke. 2003 Jul;34(7):1623-7. Epub 2003 Jun 5.PMID: 12791939 [PubMed - indexed for MEDLINE]Related articlesFree article

A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels.

Rietveld I, Janssen JA, Hofman A, Pols HA, van Duijn CM, Lamberts SW.

Eur J Endocrinol. 2003 Feb;148(2):171-5.PMID: 12590635 [PubMed - indexed for MEDLINE]Related articlesFree article