PubMed

Connective tissue growth factor and susceptibility to renal and vascular disease risk in type 1 diabetes.

Jaffa AA, Usinger WR, McHenry MB, Jaffa MA, Lipstiz SR, Lackland D, Lopes-Virella M, Luttrell LM, Wilson PW; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Group.

J Clin Endocrinol Metab. 2008 May;93(5):1893-900. Epub 2008 Mar 4.PMID: 18319310 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells.

El-Shewy HM, Lee MH, Obeid LM, Jaffa AA, Luttrell LM.

J Biol Chem. 2007 Sep 7;282(36):26150-7. Epub 2007 Jul 9.PMID: 17620336 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted deletion of B2-kinin receptors protects against the development of diabetic nephropathy.

Tan Y, Keum JS, Wang B, McHenry MB, Lipsitz SR, Jaffa AA.

Am J Physiol Renal Physiol. 2007 Oct;293(4):F1026-35. Epub 2007 Jun 27.PMID: 17596525 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors.

El-Shewy HM, Johnson KR, Lee MH, Jaffa AA, Obeid LM, Luttrell LM.

J Biol Chem. 2006 Oct 20;281(42):31399-407. Epub 2006 Aug 22.PMID: 16926156 [PubMed - indexed for MEDLINE]Related articlesFree article

Pioglitazone inhibits connective tissue growth factor expression in advanced atherosclerotic plaques in low-density lipoprotein receptor-deficient mice.

Game BA, He L, Jarido V, Nareika A, Jaffa AA, Lopes-Virella MF, Huang Y.

Atherosclerosis. 2007 May;192(1):85-91. Epub 2006 Aug 9.PMID: 16901490 [PubMed - indexed for MEDLINE]Related articles

Renal kallikrein: a risk marker for nephropathy in children with sickle cell disease.

Bergmann S, Zheng D, Barredo J, Abboud MR, Jaffa AA.

J Pediatr Hematol Oncol. 2006 Mar;28(3):147-53.PMID: 16679937 [PubMed - indexed for MEDLINE]Related articles

Bradykinin B2 receptor knockout mice are protected from thrombosis by increased nitric oxide and prostacyclin.

Shariat-Madar Z, Mahdi F, Warnock M, Homeister JW, Srikanth S, Krijanovski Y, Murphey LJ, Jaffa AA, Schmaier AH.

Blood. 2006 Jul 1;108(1):192-9. Epub 2006 Mar 2.PMID: 16514058 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of low-density lipoprotein-induced expression of connective tissue growth factor in human aortic endothelial cells.

Sohn M, Tan Y, Wang B, Klein RL, Trojanowska M, Jaffa AA.

Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1624-34. Epub 2005 Nov 4.PMID: 16272194 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for low-density lipoprotein-induced expression of connective tissue growth factor in mesangial cells.

Sohn M, Tan Y, Klein RL, Jaffa AA.

Kidney Int. 2005 Apr;67(4):1286-96.PMID: 15780081 [PubMed - indexed for MEDLINE]Related articles

Mechanisms through which bradykinin promotes glomerular injury in diabetes.

Tan Y, Wang B, Keum JS, Jaffa AA.

Am J Physiol Renal Physiol. 2005 Mar;288(3):F483-92.PMID: 15692059 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of reactive oxygen species in bradykinin-induced proliferation of vascular smooth muscle cells.

Velarde V, de la Cerda PM, Duarte C, Arancibia F, Abbott E, González A, Moreno F, Jaffa AA.

Biol Res. 2004;37(3):419-30.PMID: 15515967 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of angiotensin II-induced expression of B2 kinin receptors.

Tan Y, Hutchison FN, Jaffa AA.

Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H926-32.PMID: 14766673 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma prekallikrein: a risk marker for hypertension and nephropathy in type 1 diabetes.

Jaffa AA, Durazo-Arvizu R, Zheng D, Lackland DT, Srikanth S, Garvey WT, Schmaier AH; DCCT/EDIC Study Group.

Diabetes. 2003 May;52(5):1215-21.PMID: 12716755 [PubMed - indexed for MEDLINE]Related articlesFree article

Utilization of a radioimmunoassay to detect the generation of Arg-Pro-Pro-Gly-Phe, a stable endproduct of bradykinin metabolism (from cultured rat aortic smooth muscle cells exposed to bradykinin).

Morinelli TA, Meier GP, Webb JG, Jaffa AA, Privitera PJ, Margolius HS.

Int Immunopharmacol. 2002 Dec;2(13-14):1995-2003.PMID: 12489813 [PubMed - indexed for MEDLINE]Related articles

Diabetes modulates the expression of glomerular kinin receptors.

Christopher J, Jaffa AA.

Int Immunopharmacol. 2002 Dec;2(13-14):1771-9.PMID: 12489791 [PubMed - indexed for MEDLINE]Related articles

Synthesis and analysis of potent, more lipophilic derivatives of the bradykinin B2 receptor antagonist peptide Hoe 140.

Kennedy KJ, Orwig KS, Dix TA, Christopher J, Jaffa AA.

J Pept Res. 2002 Apr;59(4):139-48.PMID: 11972749 [PubMed - indexed for MEDLINE]Related articles

Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo.

Wei CC, Ferrario CM, Brosnihan KB, Farrell DM, Bradley WE, Jaffa AA, Dell'Italia LJ.

J Pharmacol Exp Ther. 2002 Jan;300(1):324-9.PMID: 11752132 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipids stimulate the production of 6-keto-prostaglandin f(1alpha) in human dorsal hand veins.

Haastrup A, Gadegbeku CA, Zhang D, Mukhin YV, Greene EL, Jaffa AA, Egan BM.

Hypertension. 2001 Oct;38(4):858-63.PMID: 11641299 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of B(1)-kinin receptors in vascular smooth muscle cells: cellular mechanisms of map kinase activation.

Christopher J, Velarde V, Jaffa AA.

Hypertension. 2001 Sep;38(3 Pt 2):602-5.PMID: 11566939 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of MAPK by modified low-density lipoproteins in vascular smooth muscle cells.

Velarde V, Jenkins AJ, Christopher J, Lyons TJ, Jaffa AA.

J Appl Physiol. 2001 Sep;91(3):1412-20.PMID: 11509543 [PubMed - indexed for MEDLINE]Related articlesFree article

Bradykinin B2 receptors activate Na+/H+ exchange in mIMCD-3 cells via Janus kinase 2 and Ca2+/calmodulin.

Mukhin YV, Vlasova T, Jaffa AA, Collinsworth G, Bell JL, Tholanikunnel BG, Pettus T, Fitzgibbon W, Ploth DW, Raymond JR, Garnovskaya MN.

J Biol Chem. 2001 May 18;276(20):17339-46. Epub 2001 Feb 16.PMID: 11278760 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of B(2)-kinin receptors by glucose in vascular smooth muscle cells.

Christopher J, Velarde V, Zhang D, Mayfield D, Mayfield RK, Jaffa AA.

Am J Physiol Heart Circ Physiol. 2001 Apr;280(4):H1537-46.PMID: 11247764 [PubMed - indexed for MEDLINE]Related articlesFree article

A metabolic fragment of bradykinin, Arg-Pro-Pro-Gly-Phe, protects against the deleterious effects of lipopolysaccharide in rats.

Morinelli TA, Webb JG, Jaffa AA, Privitera PJ, Margolius HS.

J Pharmacol Exp Ther. 2001 Jan;296(1):71-6.PMID: 11123364 [PubMed - indexed for MEDLINE]Related articlesFree article

Native and modified LDL activate extracellular signal-regulated kinases in mesangial cells.

Jenkins AJ, Velarde V, Klein RL, Joyce KC, Phillips KD, Mayfield RK, Lyons TJ, Jaffa AA.

Diabetes. 2000 Dec;49(12):2160-9.PMID: 11118021 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms by which bradykinin promotes fibrosis in vascular smooth muscle cells: role of TGF-beta and MAPK.

Douillet CD, Velarde V, Christopher JT, Mayfield RK, Trojanowska ME, Jaffa AA.

Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2829-37.PMID: 11087238 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of reactive oxygen species in bradykinin-induced mitogen-activated protein kinase and c-fos induction in vascular cells.

Greene EL, Velarde V, Jaffa AA.

Hypertension. 2000 Apr;35(4):942-7.PMID: 10775566 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium-calmodulin mediates bradykinin-induced MAPK phosphorylation and c-fos induction in vascular cells.

Naidu PS, Velarde V, Kappler CS, Young RC, Mayfield RK, Jaffa AA.

Am J Physiol. 1999 Sep;277(3 Pt 2):H1061-8.PMID: 10484429 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of MAPK activation by bradykinin in vascular smooth muscle cells.

Velarde V, Ullian ME, Morinelli TA, Mayfield RK, Jaffa AA.

Am J Physiol. 1999 Aug;277(2 Pt 1):C253-61.PMID: 10444401 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular distribution of exogenous aprotinin in the rat kidney.

Vio CP, Oestreicher E, Olavarria V, Velarde V, Mayfield RK, Jaffa AA.

Biol Chem. 1998 Oct;379(10):1271-7.PMID: 9820588 [PubMed - indexed for MEDLINE]Related articles

Oleic acid and angiotensin II induce a synergistic mitogenic response in vascular smooth muscle cells.

Lu G, Meier KE, Jaffa AA, Rosenzweig SA, Egan BM.

Hypertension. 1998 Apr;31(4):978-85.PMID: 9535424 [PubMed - indexed for MEDLINE]Related articlesFree article

Bradykinin induces tubulin phosphorylation and nuclear translocation of MAP kinase in mesangial cells.

Jaffa AA, Miller BS, Rosenzweig SA, Naidu PS, Velarde V, Mayfield RK.

Am J Physiol. 1997 Dec;273(6 Pt 2):F916-24.PMID: 9435680 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of renal kallikrein and renin gene expression by insulin and IGF-I in the diabetic rat.

Jaffa AA, Vio C, Velarde V, LeRoith D, Mayfield RK.

Diabetes. 1997 Dec;46(12):2049-56.PMID: 9392495 [PubMed - indexed for MEDLINE]Related articles

Tyrosine phosphorylation of phosphatidylinositol 3-kinase and of the thromboxane A2 (TXA2) receptor by the TXA2 mimetic I-BOP in A7r5 cells.

Morinelli TA, Finley EL, Jaffa AA, Kurtz DT, Ullian ME.

Biochem Pharmacol. 1997 Jun 15;53(12):1823-32.PMID: 9256157 [PubMed - indexed for MEDLINE]Related articles

Bradykinin B2 receptor modulates renal prostaglandin E2 and nitric oxide.

Siragy HM, Jaffa AA, Margolius HS.

Hypertension. 1997 Mar;29(3):757-62.PMID: 9052892 [PubMed - indexed for MEDLINE]Related articlesFree article

Renin-angiotensin system modulates renal bradykinin production.

Siragy HM, Jaffa AA, Margolius HS, Carey RM.

Am J Physiol. 1996 Oct;271(4 Pt 2):R1090-5.PMID: 8898005 [PubMed - indexed for MEDLINE]Related articles

Modulation of renal kallikrein production by dietary protein in streptozotocin-induced diabetic rats.

Jaffa AA, Silva RH, Kim B, Mayfield RK.

J Am Soc Nephrol. 1996 May;7(5):721-7.PMID: 8738807 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of kinins in the renal response to enalaprilat in normotensive and hypertensive rats.

Fitzgibbon WR, Jaffa AA, Mayfield RK, Ploth DW.

Hypertension. 1996 Feb;27(2):235-44.PMID: 8567046 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle kallikrein. Potential role in metabolic regulation.

Mayfield RK, Shimojo N, Jaffa AA.

Diabetes. 1996 Jan;45 Suppl 1:S20-3. Review.PMID: 8529795 [PubMed - indexed for MEDLINE]Related articles

Kinin, a mediator of diabetes-induced glomerular hyperfiltration.

Jaffa AA, Rust PF, Mayfield RK.

Diabetes. 1995 Feb;44(2):156-60.PMID: 7859934 [PubMed - indexed for MEDLINE]Related articles

Rat renal interstitial bradykinin, prostaglandin E2, and cyclic guanosine 3',5'-monophosphate. Effects of altered sodium intake.

Siragy HM, Ibrahim MM, Jaffa AA, Mayfield R, Margolius HS.

Hypertension. 1994 Jun;23(6 Pt 2):1068-70.PMID: 8206596 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor I produces renal hyperfiltration by a kinin-mediated mechanism.

Jaffa AA, LeRoith D, Roberts CT Jr, Rust PF, Mayfield RK.

Am J Physiol. 1994 Jan;266(1 Pt 2):F102-7.PMID: 8304475 [PubMed - indexed for MEDLINE]Related articles

Stimulation of renal interstitial bradykinin by sodium depletion.

Siragy HM, Jaffa AA, Margolius HS.

Am J Hypertens. 1993 Oct;6(10):863-6.PMID: 8267942 [PubMed - indexed for MEDLINE]Related articles

Altered renal kallikrein and renin gene expression in nephrotic rats and modulation by converting enzyme inhibition.

Hutchison FN, Webster SK, Jaffa AA.

J Clin Invest. 1993 Aug;92(2):1073-9.PMID: 8349789 [PubMed - indexed for MEDLINE]Related articlesFree article

Thromboxane A2/prostaglandin H2 receptors in streptozotocin-induced diabetes: effects of insulin therapy in the rat.

Morinelli TA, Tempel GE, Jaffa AA, Silva RH, Naka M, Folger W, Halushka PV.

Prostaglandins. 1993 May;45(5):427-38.PMID: 8321912 [PubMed - indexed for MEDLINE]Related articles

Renal excretion of kallikrein and eicosanoids in patients with type 1 (insulin-dependent) diabetes mellitus. Relationship to glomerular and tubular function.

Harvey JN, Edmundson AW, Jaffa AA, Martin LL, Mayfield RK.

Diabetologia. 1992 Sep;35(9):857-62.PMID: 1397781 [PubMed - indexed for MEDLINE]Related articles

Evidence for renal kinins as mediators of amino acid-induced hyperperfusion and hyperfiltration in the rat.

Jaffa AA, Vio CP, Silva RH, Vavrek RJ, Stewart JM, Rust PF, Mayfield RK.

J Clin Invest. 1992 May;89(5):1460-8.PMID: 1373739 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of diabetes and insulin on expression of kallikrein and renin genes in the kidney.

Jaffa AA, Chai KX, Chao J, Chao L, Mayfield RK.

Kidney Int. 1992 Apr;41(4):789-95.PMID: 1513101 [PubMed - indexed for MEDLINE]Related articles

Renal hyperfiltration states: relationship to kallikrein and kinins.

Mayfield RK, Jaffa AA, Edmundson AW, Harvey JN.

Agents Actions Suppl. 1992;38 ( Pt 3):142-8.PMID: 1281377 [PubMed - indexed for MEDLINE]Related articles

Regulation of renal kallikrein synthesis and activation by glucocorticoids.

Jaffa AA, Miller DH, Silva RH, Margolius HS, Mayfield RK.

Kidney Int. 1990 Aug;38(2):212-8.PMID: 2205750 [PubMed - indexed for MEDLINE]Related articles

Renal kallikrein and hemodynamic abnormalities of diabetic kidney.

Harvey JN, Jaffa AA, Margolius HS, Mayfield RK.

Diabetes. 1990 Mar;39(3):299-304.PMID: 1689683 [PubMed - indexed for MEDLINE]Related articles