PubMed

Tackling the methylome: recent methodological advances in genome-wide methylation profiling.

Estécio MR, Issa JP.

Genome Med. 2009 Nov 16;1(11):106. [Epub ahead of print]PMID: 19930617 [PubMed - as supplied by publisher]Related articlesFree article

Epigenetic Profiles Distinguish Malignant Pleural Mesothelioma from Lung Adenocarcinoma.

Goto Y, Shinjo K, Kondo Y, Shen L, Toyota M, Suzuki H, Gao W, An B, Fujii M, Murakami H, Osada H, Taniguchi T, Usami N, Kondo M, Hasegawa Y, Shimokata K, Matsuo K, Hida T, Fujimoto N, Kishimoto T, Issa JP, Sekido Y.

Cancer Res. 2009 Dec 1;69(23):9073-9082. Epub 2009 Nov 3.PMID: 19887624 [PubMed - as supplied by publisher]Related articles

Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities.

Ravandi F, Issa JP, Garcia-Manero G, O'Brien S, Pierce S, Shan J, Borthakur G, Verstovsek S, Faderl S, Cortes J, Kantarjian H.

Cancer. 2009 Sep 30;115(24):5746-5751. [Epub ahead of print]PMID: 19795507 [PubMed - as supplied by publisher]Related articles

Concordant DNA methylation in synchronous colorectal carcinomas.

Konishi K, Shen L, Jelinek J, Watanabe Y, Ahmed S, Kaneko K, Kogo M, Takano T, Imawari M, Hamilton SR, Issa JP.

Cancer Prev Res (Phila Pa). 2009 Sep;2(9):814-22. Epub 2009 Sep 8.PMID: 19737982 [PubMed - indexed for MEDLINE]Related articles

Effect of recombinant human bone morphogenetic protein-2 on bone formation in the acute distraction osteogenesis of rat mandibles.

Issa JP, do Nascimento C, Lamano T, Iyomasa MM, Sebald W, de Albuquerque RF Jr.

Clin Oral Implants Res. 2009 Nov;20(11):1286-92. Epub 2009 Aug 30.PMID: 19719732 [PubMed - in process]Related articles

The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities: how does it relate to the original lenalidomide experience in MDS?

Kantarjian H, O'Brien S, Ravandi F, Borthakur G, Faderl S, Bueso-Ramos C, Abruzzo L, Pierce S, Shan J, Issa JP, Garcia-Manero G.

Cancer. 2009 Nov 15;115(22):5202-9.PMID: 19691096 [PubMed - in process]Related articles

IGFBP7 is a p53 Responsive Gene Specifically Silenced in Colorectal Cancer with CpG Island Methylator Phenotype.

Suzuki H, Igarashi S, Nojima M, Maruyama R, Yamamoto E, Kai M, Akashi H, Watanabe Y, Yamamoto H, Sasaki Y, Itoh F, Imai K, Sugai T, Shen L, Issa JP, Shinomura Y, Tokino T, Toyota M.

Carcinogenesis. 2009 Jul 28. [Epub ahead of print]PMID: 19638426 [PubMed - as supplied by publisher]Related articles

Elongated styloid process and atheroma in panoramic radiography and its relationship with systemic osteoporosis and osteopenia.

Watanabe PC, Dias FC, Issa JP, Monteiro SA, de Paula FJ, Tiossi R.

Osteoporos Int. 2009 Jul 24. [Epub ahead of print]PMID: 19629615 [PubMed - as supplied by publisher]Related articles

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia.

Loh ML, Sakai DS, Flotho C, Kang M, Fliegauf M, Archambeault S, Mullighan CG, Chen L, Bergstraesser E, Bueso-Ramos CE, Emanuel PD, Hasle H, Issa JP, van den Heuvel-Eibrink MM, Locatelli F, Stary J, Trebo M, Wlodarski M, Zecca M, Shannon KM, Niemeyer CM.

Blood. 2009 Aug 27;114(9):1859-63. Epub 2009 Jul 1.PMID: 19571318 [PubMed - indexed for MEDLINE]Related articles

Targeting DNA methylation.

Issa JP, Kantarjian HM.

Clin Cancer Res. 2009 Jun 15;15(12):3938-46. Epub 2009 Jun 9.PMID: 19509174 [PubMed - indexed for MEDLINE]Related articles

Use of the DNA Checkerboard hybridization method for detection and quantitation of Candida species in oral microbiota.

do Nascimento C, Ferreira de Albuquerque Junior R, Issa JP, Ito IY, Lovato da Silva CH, de Freitas Oliveira Paranhos H, de Souza RF.

Can J Microbiol. 2009 May;55(5):622-6.PMID: 19483792 [PubMed - indexed for MEDLINE]Related articles

Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.

Stewart DJ, Issa JP, Kurzrock R, Nunez MI, Jelinek J, Hong D, Oki Y, Guo Z, Gupta S, Wistuba II.

Clin Cancer Res. 2009 Jun 1;15(11):3881-8. Epub 2009 May 26.PMID: 19470736 [PubMed - indexed for MEDLINE]Related articles

CpG island methylation profiling in human melanoma cell lines.

Tellez CS, Shen L, Estécio MR, Jelinek J, Gershenwald JE, Issa JP.

Melanoma Res. 2009 Jun;19(3):146-55.PMID: 19441164 [PubMed - indexed for MEDLINE]Related articles

LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.

Aparicio A, North B, Barske L, Wang X, Bollati V, Weisenberger D, Yoo C, Tannir N, Horne E, Groshen S, Jones P, Yang A, Issa JP.

Epigenetics. 2009 Apr;4(3):176-84. Epub 2009 Apr 6.PMID: 19421002 [PubMed - indexed for MEDLINE]Related articlesFree article

Collagen fibers evaluation after rhBMP-2 insertion in critical-sized defects.

Issa JP, Pitol DL, Iyomasa MM, Barbosa AP, Defino HL, Volpon JB, Shimano AC, Silva P.

Micron. 2009 Jul-Aug;40(5-6):560-2. Epub 2009 Apr 5.PMID: 19394235 [PubMed - indexed for MEDLINE]Related articles

Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics.

Heinrichs S, Kulkarni RV, Bueso-Ramos CE, Levine RL, Loh ML, Li C, Neuberg D, Kornblau SM, Issa JP, Gilliland DG, Garcia-Manero G, Kantarjian HM, Estey EH, Look AT.

Leukemia. 2009 Sep;23(9):1605-13. Epub 2009 Apr 23.PMID: 19387468 [PubMed - indexed for MEDLINE]Related articles

Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes.

Watanabe Y, Kim HS, Castoro RJ, Chung W, Estecio MR, Kondo K, Guo Y, Ahmed SS, Toyota M, Itoh F, Suk KT, Cho MY, Shen L, Jelinek J, Issa JP.

Gastroenterology. 2009 Jun;136(7):2149-58. Epub 2009 Apr 16.PMID: 19375421 [PubMed - indexed for MEDLINE]Related articles

Bacterial culture and DNA Checkerboard for the detection of internal contamination in dental implants.

Barbosa RE, do Nascimento C, Issa JP, Watanabe E, Ito IY, de Albuquerque RF Jr.

J Prosthodont. 2009 Jul;18(5):376-81. Epub 2009 Apr 3.PMID: 19374709 [PubMed - indexed for MEDLINE]Related articles

Shear-bond strength between a new format of intra-buccal acrylic bioadhesive drug delivery system and adhesive systems.

Pedrazzi V, Del Ciampo JO, Panzeri H, Lara EH, Issa JP, Do Nascimento C.

Minerva Stomatol. 2009 Apr;58(4):145-50.PMID: 19369920 [PubMed - indexed for MEDLINE]Related articles

Histone deacetylase inhibitors as anti-neoplastic agents.

Batty N, Malouf GG, Issa JP.

Cancer Lett. 2009 Aug 8;280(2):192-200. Epub 2009 Apr 3. Review.PMID: 19345475 [PubMed - indexed for MEDLINE]Related articles

Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.

Ware CB, Wang L, Mecham BH, Shen L, Nelson AM, Bar M, Lamba DA, Dauphin DS, Buckingham B, Askari B, Lim R, Tewari M, Gartler SM, Issa JP, Pavlidis P, Duan Z, Blau CA.

Cell Stem Cell. 2009 Apr 3;4(4):359-69.PMID: 19341625 [PubMed - indexed for MEDLINE]Related articles

Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors.

Figueiredo JC, Grau MV, Wallace K, Levine AJ, Shen L, Hamdan R, Chen X, Bresalier RS, McKeown-Eyssen G, Haile RW, Baron JA, Issa JP.

Cancer Epidemiol Biomarkers Prev. 2009 Apr;18(4):1041-9. Epub 2009 Mar 31.PMID: 19336559 [PubMed - indexed for MEDLINE]Related articles

Using short-term response information to facilitate adaptive randomization for survival clinical trials.

Huang X, Ning J, Li Y, Estey E, Issa JP, Berry DA.

Stat Med. 2009 May 30;28(12):1680-9.PMID: 19326367 [PubMed - indexed for MEDLINE]Related articles

Morphodigital study of bone quality in the mandibular angle in patients with third molar impacted.

Watanabe PC, Alonso MB, Monteiro SA, Tiossi R, Issa JP.

Anat Sci Int. 2009 Sep;84(3):246-52. Epub 2009 Mar 27.PMID: 19326188 [PubMed - in process]Related articles

Ultrastructural analysis of the low level laser therapy effects on the lesioned anterior tibial muscle in the gerbil.

Iyomasa DM, Garavelo I, Iyomasa MM, Watanabe IS, Issa JP.

Micron. 2009 Jun;40(4):413-8. Epub 2009 Feb 13.PMID: 19269186 [PubMed - indexed for MEDLINE]Related articles

Use of checkerboard DNA-DNA hybridization to evaluate the internal contamination of dental implants and comparison of bacterial leakage with cast or pre-machined abutments.

do Nascimento C, Barbosa RE, Issa JP, Watanabe E, Ito IY, de Albuquerque Junior RF.

Clin Oral Implants Res. 2009 Jun;20(6):571-7. Epub 2009 Feb 25.PMID: 19250244 [PubMed - indexed for MEDLINE]Related articles

Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome.

De Padua Silva L, de Lima M, Kantarjian H, Faderl S, Kebriaei P, Giralt S, Davisson J, Garcia-Manero G, Champlin R, Issa JP, Ravandi F.

Bone Marrow Transplant. 2009 Jun;43(11):839-43. Epub 2009 Jan 19.PMID: 19151791 [PubMed - indexed for MEDLINE]Related articles

Cancer prevention: epigenetics steps up to the plate.

Issa JP.

Cancer Prev Res (Phila Pa). 2008 Sep;1(4):219-22. Epub 2008 Mar 19. No abstract available. PMID: 19138962 [PubMed - indexed for MEDLINE]Related articles

Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas.

Kim MJ, White-Cross JA, Shen L, Issa JP, Rashid A.

Mod Pathol. 2009 Mar;22(3):442-9. Epub 2009 Jan 9.PMID: 19136926 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural characteristics of the gerbil pterygoid medial muscle after experimental occlusal alteration.

Iyomasa MM, Issa JP, Sosthines MC, Oliveira AM, Stuani MB, Motoyama AA, Watanabe IS.

Micron. 2009 Feb;40(2):206-11. Epub 2008 Sep 23.PMID: 18977663 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines.

Qin T, Jelinek J, Si J, Shu J, Issa JP.

Blood. 2009 Jan 15;113(3):659-67. Epub 2008 Oct 17.PMID: 18931345 [PubMed - indexed for MEDLINE]Related articles

Colon cancer: it's CIN or CIMP.

Issa JP.

Clin Cancer Res. 2008 Oct 1;14(19):5939-40.PMID: 18829469 [PubMed - indexed for MEDLINE]Related articlesFree article

Histological and histochemical effects after occlusion alteration in suprahyoid muscles.

Iyomasa MM, de Souza Guerra C, Dias FJ, Pitol DL, Watanabe IS, Issa JP.

Micron. 2009 Feb;40(2):239-46. Epub 2008 Aug 19.PMID: 18823787 [PubMed - indexed for MEDLINE]Related articles

Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years.

Kantarjian H, O'Brien S, Cortes J, Wierda W, Faderl S, Garcia-Manero G, Issa JP, Estey E, Keating M, Freireich EJ.

Cancer. 2008 Oct 1;113(7 Suppl):1933-52. Review.PMID: 18798533 [PubMed - indexed for MEDLINE]Related articlesFree article

Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma.

Fens MH, Hill KJ, Issa J, Ashton SE, Westwood FR, Blakey DC, Storm G, Ryan AJ, Schiffelers RM.

Br J Cancer. 2008 Oct 21;99(8):1256-64. Epub 2008 Sep 16.PMID: 18797467 [PubMed - indexed for MEDLINE]Related articlesFree article

An Sp1/Sp3 binding polymorphism confers methylation protection.

Boumber YA, Kondo Y, Chen X, Shen L, Guo Y, Tellez C, Estécio MR, Ahmed S, Issa JP.

PLoS Genet. 2008 Aug 22;4(8):e1000162.PMID: 18725933 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of unilateral extraction of molar teeth on suprahyoid muscles: macroscopic and ultrastructural aspects.

Iyomasa MM, Issa JP, Siéssere S, Regalo SC, Watanabe IS.

Micron. 2008 Dec;39(8):1111-8. Epub 2008 Jul 11.PMID: 18693023 [PubMed - indexed for MEDLINE]Related articles

Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas.

Gao W, Kondo Y, Shen L, Shimizu Y, Sano T, Yamao K, Natsume A, Goto Y, Ito M, Murakami H, Osada H, Zhang J, Issa JP, Sekido Y.

Carcinogenesis. 2008 Oct;29(10):1901-10. Epub 2008 Jul 16.PMID: 18632756 [PubMed - indexed for MEDLINE]Related articlesFree article

Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System.

Kantarjian H, O'Brien S, Ravandi F, Cortes J, Shan J, Bennett JM, List A, Fenaux P, Sanz G, Issa JP, Freireich EJ, Garcia-Manero G.

Cancer. 2008 Sep 15;113(6):1351-61.PMID: 18618511 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.

Kuang SQ, Tong WG, Yang H, Lin W, Lee MK, Fang ZH, Wei Y, Jelinek J, Issa JP, Garcia-Manero G.

Leukemia. 2008 Aug;22(8):1529-38. Epub 2008 Jun 5.PMID: 18528427 [PubMed - indexed for MEDLINE]Related articles

Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse.

Kroeger H, Jelinek J, Estécio MR, He R, Kondo K, Chung W, Zhang L, Shen L, Kantarjian HM, Bueso-Ramos CE, Issa JP.

Blood. 2008 Aug 15;112(4):1366-73. Epub 2008 Jun 3.PMID: 18523155 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.

Kondo Y, Shen L, Cheng AS, Ahmed S, Boumber Y, Charo C, Yamochi T, Urano T, Furukawa K, Kwabi-Addo B, Gold DL, Sekido Y, Huang TH, Issa JP.

Nat Genet. 2008 Jun;40(6):741-50. Epub 2008 May 18.PMID: 18488029 [PubMed - indexed for MEDLINE]Related articles

Review: recent clinical trials in epigenetic therapy.

Oki Y, Issa JP.

Rev Recent Clin Trials. 2006 May;1(2):169-82. Review.PMID: 18473969 [PubMed - indexed for MEDLINE]Related articles

Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.

Majewski T, Lee S, Jeong J, Yoon DS, Kram A, Kim MS, Tuziak T, Bondaruk J, Lee S, Park WS, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, Grossman HB, Dinney CP, Zhou JH, Harris RA, Snyder C, Filipek S, Narod SA, Watson P, Lynch HT, Gazdar A, Bar-Eli M, Wu XF, McConkey DJ, Baggerly K, Issa JP, Benedict WF, Scherer SE, Czerniak B.

Lab Invest. 2008 Jul;88(7):694-721. Epub 2008 May 5.PMID: 18458673 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative promoter hypermethylation analysis of cancer-related genes in salivary gland carcinomas: comparison with methylation-specific PCR technique and clinical significance.

Lee ES, Issa JP, Roberts DB, Williams MD, Weber RS, Kies MS, El-Naggar AK.

Clin Cancer Res. 2008 May 1;14(9):2664-72.PMID: 18451230 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.

Suehiro Y, Wong CW, Chirieac LR, Kondo Y, Shen L, Webb CR, Chan YW, Chan AS, Chan TL, Wu TT, Rashid A, Hamanaka Y, Hinoda Y, Shannon RL, Wang X, Morris J, Issa JP, Yuen ST, Leung SY, Hamilton SR.

Clin Cancer Res. 2008 May 1;14(9):2560-9.PMID: 18451217 [PubMed - indexed for MEDLINE]Related articlesFree article

Mononuclear phagocytes in the blood of turtles characterized by ultrastructural and cytochemical analyses and by phagocytic activity.

Pitol DL, Issa JP, Caetano FH, Lunardi LO.

Micron. 2008 Dec;39(8):1288-92. Epub 2008 Mar 20.PMID: 18448345 [PubMed - indexed for MEDLINE]Related articles

Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling.

Chung W, Kwabi-Addo B, Ittmann M, Jelinek J, Shen L, Yu Y, Issa JP.

PLoS One. 2008 Apr 30;3(4):e2079. Erratum in: PLoS ONE. 2008;3(5). doi: 10.1371/annotation/2548989f-1f13-4ea5-8af8-62420b0a590e. PMID: 18446232 [PubMed - indexed for MEDLINE]Related articlesFree article

Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells.

Kondo Y, Shen L, Ahmed S, Boumber Y, Sekido Y, Haddad BR, Issa JP.

PLoS One. 2008 Apr 30;3(4):e2037.PMID: 18446223 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies.

Jabbour E, Issa JP, Garcia-Manero G, Kantarjian H.

Cancer. 2008 Jun;112(11):2341-51. Review.PMID: 18398832 [PubMed - indexed for MEDLINE]Related articlesFree article