PubMed

LDLR promoter variant and exon 14 mutation on the same chromosome are associated with an unusually severe FH phenotype and treatment resistance.

Snozek CL, Lagerstedt SA, Khoo TK, Rubenfire M, Isley WL, Train LJ, Baudhuin LM.

Eur J Hum Genet. 2009 Jan;17(1):85-90. Epub 2008 Jul 23.PMID: 18648394 [PubMed - indexed for MEDLINE]Related articles

Patient-important outcomes in registered diabetes trials.

Gandhi GY, Murad MH, Fujiyoshi A, Mullan RJ, Flynn DN, Elamin MB, Swiglo BA, Isley WL, Guyatt GH, Montori VM.

JAMA. 2008 Jun 4;299(21):2543-9.PMID: 18523223 [PubMed - indexed for MEDLINE]Related articlesFree article

No, the glycaemic target in the critically ill should not be < or = 6.1 mmol/l.

Miles JM, McMahon MM, Isley WL.

Diabetologia. 2008 Jun;51(6):916-20. Epub 2007 Dec 20. No abstract available. PMID: 18094956 [PubMed - indexed for MEDLINE]Related articles

Glycemic variation and hypoglycemia in patients with well-controlled type 1 diabetes on a multiple daily insulin injection program with use of glargine and ultralente as basal insulin.

Kudva YC, Basu A, Jenkins GD, Pons GM, Vogelsang DA, Rizza RA, Smith SA, Isley WL.

Endocr Pract. 2007 May-Jun;13(3):244-50.PMID: 17599855 [PubMed - indexed for MEDLINE]Related articles

Waking up from the DREAM of preventing diabetes with drugs.

Montori VM, Isley WL, Guyatt GH.

BMJ. 2007 Apr 28;334(7599):882-4. Review. No abstract available. PMID: 17463460 [PubMed - indexed for MEDLINE]Related articles

Pioglitazone did not reduce macrovascular complications and increased HF in type 2 diabetes with macrovascular disease.

Isley WL.

Evid Based Med. 2006 Apr;11(2):47. No abstract available. PMID: 17213077 [PubMed]Related articles

Review: ACE inhibitors and angiotensin-receptor blockers reduce diabetes in hypertension and other CV risk factors.

Gandhi GY, Isley WL.

ACP J Club. 2007 Jan-Feb;146(1):11. No abstract available. PMID: 17203931 [PubMed]Related articles

Ramipril did not reduce incident diabetes in patients with impaired glycemic control.

Gandhi GY, Isley WL.

ACP J Club. 2007 Jan-Feb;146(1):10. No abstract available. PMID: 17203930 [PubMed]Related articles

Comparison of apolipoprotein-B/apolipoprotein-AI in subjects with versus without the metabolic syndrome.

Sierra-Johnson J, Somers VK, Kuniyoshi FH, Garza CA, Isley WL, Gami AS, Lopez-Jimenez F.

Am J Cardiol. 2006 Nov 15;98(10):1369-73. Epub 2006 Sep 29.PMID: 17134631 [PubMed - indexed for MEDLINE]Related articles

Low-density Lipoprotein Cholesterol Lowering in the Prevention of CHD: How Low Should We Go?

Isley WL.

Curr Treat Options Cardiovasc Med. 2006 Aug;8(4):289-97.PMID: 17038269 [PubMed - in process]Related articles

The effect of high dose simvastatin on, platelet size in patients with, type 2 diabetes mellitus.

Isley WL, Park Y, Harris WS.

Platelets. 2006 Aug;17(5):292-5.PMID: 16928600 [PubMed - indexed for MEDLINE]Related articles

Problems with measurements of hemoglobin A1c.

Smith SA, Montori VM, Isley WL, Burritt MF.

Mayo Clin Proc. 2006 Aug;81(8):1130. No abstract available. PMID: 16901036 [PubMed - indexed for MEDLINE]Related articlesFree article

Rationale, design, and methods for glycemic control in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial.

Magee MF, Isley WL; BARI 2D Trial Investigators.

Am J Cardiol. 2006 Jun 19;97(12A):20G-30G. Epub 2006 Apr 19.PMID: 16813735 [PubMed - indexed for MEDLINE]Related articles

The effect of high-dose simvastatin on free fatty acid metabolism in patients with type 2 diabetes mellitus.

Isley WL, Harris WS, Miles JM.

Metabolism. 2006 Jun;55(6):758-62.PMID: 16713435 [PubMed - indexed for MEDLINE]Related articles

Pioglitazone did not reduce a composite endpoint of macrovascular complications and increased risk for heart failure in type 2 diabetes with macrovascular disease.

Isley WL.

ACP J Club. 2006 Mar-Apr;144(2):34. No abstract available. PMID: 16539349 [PubMed]Related articles

Ketoacidosis during a low-carbohydrate diet.

Shah P, Isley WL.

N Engl J Med. 2006 Jan 5;354(1):97-8. No abstract available. PMID: 16394313 [PubMed - indexed for MEDLINE]Related articles

Review: alpha-glucosidase inhibitors improve glycemic control but have uncertain effects on patient-important outcomes in type 2 diabetes.

Isley WL.

ACP J Club. 2005 Nov-Dec;143(3):66. No abstract available. PMID: 16262223 [PubMed]Related articles

The effect of high-dose simvastatin on triglyceride-rich lipoprotein metabolism in patients with type 2 diabetes mellitus.

Isley WL, Miles JM, Patterson BW, Harris WS.

J Lipid Res. 2006 Jan;47(1):193-200. Epub 2005 Oct 28.PMID: 16258165 [PubMed - indexed for MEDLINE]Related articlesFree article

Getting there: statin plus ezetimibe for low-density lipoprotein cholesterol goals.

Hurley DL, Isley WL.

Mayo Clin Proc. 2005 May;80(5):585-6. No abstract available. PMID: 15887424 [PubMed - indexed for MEDLINE]Related articlesFree article

What did PROVE-IT prove?

Isley WL; PROVE-IT-TIMI 22.

Diabetes Technol Ther. 2004 Dec;6(6):864-7. No abstract available. PMID: 15684640 [PubMed - indexed for MEDLINE]Related articles

High-dose statins in acute coronary syndromes.

Isley WL.

JAMA. 2005 Jan 5;293(1):37-8; author reply 38-9. No abstract available. PMID: 15632329 [PubMed - indexed for MEDLINE]Related articles

Randomized controlled clinical trial of glargine versus ultralente insulin in the treatment of type 1 diabetes.

Kudva YC, Basu A, Jenkins GD, Pons GM, Quandt LL, Gebel JA, Vogelsang DA, Smith SA, Rizza RA, Isley WL.

Diabetes Care. 2005 Jan;28(1):10-4.PMID: 15616226 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variants of ApoE account for variability of plasma low-density lipoprotein and apolipoprotein B levels in FHBL.

Yue P, Isley WL, Harris WS, Rosipal S, Akin CD, Schonfeld G.

Atherosclerosis. 2005 Jan;178(1):107-13.PMID: 15585207 [PubMed - indexed for MEDLINE]Related articles

Insulin: thoroughly modern therapy.

Isley WL.

Endocr Pract. 2004 May-Jun;10(3):289-90. No abstract available. PMID: 15310550 [PubMed - indexed for MEDLINE]Related articles

Systemic and forearm triglyceride metabolism: fate of lipoprotein lipase-generated glycerol and free fatty acids.

Miles JM, Park YS, Walewicz D, Russell-Lopez C, Windsor S, Isley WL, Coppack SW, Harris WS.

Diabetes. 2004 Mar;53(3):521-7.PMID: 14988233 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatotoxicity of thiazolidinediones.

Isley WL.

Expert Opin Drug Saf. 2003 Nov;2(6):581-6. Review.PMID: 14585066 [PubMed - indexed for MEDLINE]Related articles

Pitavastatin (NK-104), a new HMG-CoA reductase inhibitor.

Isley WL.

Drugs Today (Barc). 2001 Sep;37(9):587-594.PMID: 12743630 [PubMed - as supplied by publisher]Related articles

Glitazones: good for glycemia. Good for the liver?

Isley WL.

Diabetes Technol Ther. 2003;5(1):43-4. No abstract available. PMID: 12725706 [PubMed - indexed for MEDLINE]Related articles

Nocturnal and postprandial free fatty acid kinetics in normal and type 2 diabetic subjects: effects of insulin sensitization therapy.

Miles JM, Wooldridge D, Grellner WJ, Windsor S, Isley WL, Klein S, Harris WS.

Diabetes. 2003 Mar;52(3):675-81.PMID: 12606508 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperthyroidism: a "curable" cause of congestive heart failure--three case reports and a review of the literature.

Riaz K, Forker AD, Isley WL, Hamburg MS, McCullough PA.

Congest Heart Fail. 2003 Jan-Feb;9(1):40-6. Review.PMID: 12556677 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular disease and long-chain omega-3 fatty acids.

Harris WS, Park Y, Isley WL.

Curr Opin Lipidol. 2003 Feb;14(1):9-14. Review.PMID: 12544655 [PubMed - indexed for MEDLINE]Related articles

Growth hormone therapy for adults: not ready for prime time?

Isley WL.

Ann Intern Med. 2002 Aug 6;137(3):190-6. Review.PMID: 12160367 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel mutations of APOB cause ApoB truncations undetectable in plasma and familial hypobetalipoproteinemia.

Yue P, Yuan B, Gerhard DS, Neuman RJ, Isley WL, Harris WS, Schonfeld G.

Hum Mutat. 2002 Aug;20(2):110-6. Erratum in: Hum Mutat 2002 Nov;20(5):402. PMID: 12124991 [PubMed - indexed for MEDLINE]Related articles

Massah and mechanisms.

Harris WS, Isley WL.

Arch Intern Med. 2002 Jun 24;162(12):1420. No abstract available. PMID: 12076243 [PubMed - indexed for MEDLINE]Related articles

Hepatotoxicity of thiazolidinediones.

Isley WL, Oki JC.

Diabetes Obes Metab. 2001 Dec;3(6):389-92. Review. No abstract available. PMID: 11903409 [PubMed - indexed for MEDLINE]Related articles

Glitazones, glycemia, and global health status.

Isley WL.

Diabetes Care. 2001 Dec;24(12):2158-9. No abstract available. PMID: 11723105 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical trial evidence for the cardioprotective effects of omega-3 fatty acids.

Harris WS, Isley WL.

Curr Atheroscler Rep. 2001 Mar;3(2):174-9. Review. Erratum in: Curr Atheroscler Rep 2001 Nov;3(6):iii. PMID: 11177663 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone and liver failure.

Isley WL, Oki JC.

Ann Intern Med. 2000 Sep 5;133(5):393-4. No abstract available. PMID: 10979889 [PubMed - indexed for MEDLINE]Related articlesFree article

Troglitazone-induced hepatic failure leading to liver transplantation. A case report.

Neuschwander-Tetri BA, Isley WL, Oki JC, Ramrakhiani S, Quiason SG, Phillips NJ, Brunt EM.

Ann Intern Med. 1998 Jul 1;129(1):38-41.PMID: 9652998 [PubMed - indexed for MEDLINE]Related articlesFree article

Frequency and impact of SMBG on glycemic control in patients with NIDDM in an urban teaching hospital clinic.

Oki JC, Flora DL, Isley WL.

Diabetes Educ. 1997 Jul-Aug;23(4):419-24.PMID: 9305007 [PubMed - indexed for MEDLINE]Related articles

Hypolipidemic drugs in coronary artery disease.

Isley WL.

Ann Intern Med. 1997 Jun 1;126(11):916; author reply 917. No abstract available. PMID: 9163299 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen-induced pancreatitis after discontinuation of concomitant medroxyprogesterone therapy.

Isley WL, Oki J.

Am J Med. 1997 Apr;102(4):416-7. No abstract available. PMID: 9217626 [PubMed - indexed for MEDLINE]Related articles

Endocrine emergencies. Recognizing clues to classic problems.

Reasner CA, Isley WL.

Postgrad Med. 1997 Mar;101(3):231-4, 237-8, 241-2. Review. Erratum in: Postgrad Med 1997 Nov;102(5):28. PMID: 9074561 [PubMed - indexed for MEDLINE]Related articles

How big a dose of levothyroxine?

Isley WL.

Postgrad Med. 1993 Dec;94(8):38, 45. No abstract available. PMID: 8247999 [PubMed - indexed for MEDLINE]Related articles

Thyroid dysfunction in the severely ill and elderly. Forget the classic signs and symptoms.

Isley WL.

Postgrad Med. 1993 Sep 1;94(3):111-8, 127-8. Review.PMID: 8361938 [PubMed - indexed for MEDLINE]Related articles

Efficacy and safety of reformulated, micronized glyburide tablets in patients with non-insulin-dependent diabetes mellitus: a multicenter, double-blind, randomized trial.

Carlson RF, Isley WL, Ogrinc FG, Klobucar TR.

Clin Ther. 1993 Sep-Oct;15(5):788-96.PMID: 8269445 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor-binding protein-3 proteolysis is induced after elective surgery.

Davenport ML, Isley WL, Pucilowska JB, Pemberton LB, Lyman B, Underwood LE, Clemmons DR.

J Clin Endocrinol Metab. 1992 Aug;75(2):590-5.PMID: 1379257 [PubMed - indexed for MEDLINE]Related articles

Thyrotoxicosis in the critically ill.

Reasner CA 2nd, Isley WL.

Crit Care Clin. 1991 Jan;7(1):57-74. Review.PMID: 2007220 [PubMed - indexed for MEDLINE]Related articles

Serum sodium concentration abnormalities.

Isley WL.

Crit Care Nurs Q. 1990 Nov;13(3):82-8. No abstract available. PMID: 2224570 [PubMed - indexed for MEDLINE]Related articles

Thyroid disorders.

Isley WL.

Crit Care Nurs Q. 1990 Nov;13(3):39-49. Review. No abstract available. PMID: 2224566 [PubMed - indexed for MEDLINE]Related articles