PubMed

Primary postoperative chemotherapy without radiotherapy for treatment of brain tumours other than ependymoma in children under 3 years: Results of the first UKCCSG/SIOP CNS 9204 trial.

Grundy RG, Wilne SH, Robinson KJ, Ironside JW, Cox T, Chong WK, Michalski A, Campbell RH, Bailey CC, Thorp N, Pizer B, Punt J, Walker DA, Ellison DW, Machin D; Children’s Cancer and Leukaemia Group (formerly UKCCSG) Brain Tumour Committee.

Eur J Cancer. 2009 Oct 7. [Epub ahead of print]PMID: 19818598 [PubMed - as supplied by publisher]Related articles

Sporadic Creutzfeldt-Jakob disease: discrete subtypes or a spectrum of disease?

Head MW, Ironside JW.

Brain. 2009 Oct;132(Pt 10):2627-9. Epub 2009 Sep 16. No abstract available. PMID: 19759201 [PubMed - in process]Related articles

A Case of Protease Sensitive Prionopathy in a Patient in the United Kingdom.

Head MW, Knight R, Zeidler M, Yull H, Barlow A, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Aug 7. [Epub ahead of print] No abstract available. PMID: 19671081 [PubMed - as supplied by publisher]Related articles

Transmissions of variant Creutzfeldt-Jakob disease from brain and lymphoreticular tissue show uniform and conserved bovine spongiform encephalopathy-related phenotypic properties on primary and secondary passage in wild-type mice.

Ritchie DL, Boyle A, McConnell I, Head MW, Ironside JW, Bruce ME.

J Gen Virol. 2009 Dec;90(Pt 12):3075-82. Epub 2009 Aug 5.PMID: 19656962 [PubMed - in process]Related articles

Pathological investigation of the first blood donor and recipient pair linked by transfusion-associated variant Creutzfeldt-Jakob disease transmission.

Head MW, Yull HM, Ritchie DL, Bishop MT, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Aug;35(4):433-6. Epub 2009 Apr 7. No abstract available. PMID: 19490428 [PubMed - indexed for MEDLINE]Related articles

Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients.

Jansen C, Head MW, Rozemuller AJ, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Jun;35(3):272-82.PMID: 19473294 [PubMed - indexed for MEDLINE]Related articles

Prevalence of disease related prion protein in anonymous tonsil specimens in Britain: cross sectional opportunistic survey.

Clewley JP, Kelly CM, Andrews N, Vogliqi K, Mallinson G, Kaisar M, Hilton DA, Ironside JW, Edwards P, McCardle LM, Ritchie DL, Dabaghian R, Ambrose HE, Gill ON.

BMJ. 2009 May 21;338:b1442. doi: 10.1136/bmj.b1442.PMID: 19460798 [PubMed - indexed for MEDLINE]Related articlesFree article

Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain.

Brandel JP, Heath CA, Head MW, Levavasseur E, Knight R, Laplanche JL, Langeveld JP, Ironside JW, Hauw JJ, Mackenzie J, Alpérovitch A, Will RG, Haïk S.

Ann Neurol. 2009 Mar;65(3):249-56.PMID: 19334063 [PubMed - indexed for MEDLINE]Related articles

Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium.

Alafuzoff I, Ince PG, Arzberger T, Al-Sarraj S, Bell J, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Parchi P, Parkkinen L, Patsouris E, Roggendorf W, Rozemuller A, Stadelmann-Nessler C, Streichenberger N, Thal DR, Kretzschmar H.

Acta Neuropathol. 2009 Jun;117(6):635-52. Epub 2009 Mar 28.PMID: 19330340 [PubMed - indexed for MEDLINE]Related articles

Further characterisation of the prion protein molecular types detectable in the NIBSC Creutzfeldt-Jakob disease brain reference materials.

Yull HM, Ironside JW, Head MW.

Biologicals. 2009 Aug;37(4):210-5. Epub 2009 Mar 4.PMID: 19264507 [PubMed - in process]Related articles

Familial prion disease with a novel serine to isoleucine mutation at codon 132 of prion protein gene (PRNP).

Hilton DA, Head MW, Singh VK, Bishop M, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Feb;35(1):111-5. No abstract available. PMID: 19187063 [PubMed - indexed for MEDLINE]Related articles

A quantitative study of the pathological changes in the cerebellum in 15 cases of variant Creutzfeldt-Jakob disease (vCJD).

Armstrong RA, Ironside JW, Lantos PL, Cairns NJ.

Neuropathol Appl Neurobiol. 2009 Feb;35(1):36-45.PMID: 19187059 [PubMed - indexed for MEDLINE]Related articles

Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium.

Alafuzoff I, Thal DR, Arzberger T, Bogdanovic N, Al-Sarraj S, Bodi I, Boluda S, Bugiani O, Duyckaerts C, Gelpi E, Gentleman S, Giaccone G, Graeber M, Hortobagyi T, Höftberger R, Ince P, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Nilsson T, Parchi P, Patsouris E, Pikkarainen M, Revesz T, Rozemuller A, Seilhean D, Schulz-Schaeffer W, Streichenberger N, Wharton SB, Kretzschmar H.

Acta Neuropathol. 2009 Mar;117(3):309-20. Epub 2009 Feb 1.PMID: 19184666 [PubMed - indexed for MEDLINE]Related articles

Risk of Creutzfeldt-Jakob disease transmission by ocular surgery and tissue transplantation.

Armitage WJ, Tullo AB, Ironside JW.

Eye (Lond). 2009 Oct;23(10):1926-30. Epub 2009 Jan 9.PMID: 19136921 [PubMed - in process]Related articles

Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection.

Hizume M, Kobayashi A, Teruya K, Ohashi H, Ironside JW, Mohri S, Kitamoto T.

J Biol Chem. 2009 Feb 6;284(6):3603-9. Epub 2008 Dec 10.PMID: 19074151 [PubMed - indexed for MEDLINE]Related articles

Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and UK: clinical and pathological characteristics of nine patients.

Jansen C, Head MW, Rozemuller AJ, Ironside JW.

Neuropathol Appl Neurobiol. 2008 Dec 1. [Epub ahead of print]PMID: 19055524 [PubMed - as supplied by publisher]Related articles

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrP) associated with variant Creutzfeldt-Jakob disease.

Jones M, Peden AH, Yull H, Wight D, Bishop MT, Prowse CV, Turner ML, Ironside JW, MacGregor IR, Head MW.

Transfusion. 2009 Feb;49(2):376-84. Epub 2008 Oct 29.PMID: 18980616 [PubMed - indexed for MEDLINE]Related articles

Effects of human PrPSc type and PRNP genotype in an in-vitro conversion assay.

Jones M, Peden AH, Wight D, Prowse C, Macgregor I, Manson J, Turner M, Ironside JW, Head MW.

Neuroreport. 2008 Dec 3;19(18):1783-6.PMID: 18955905 [PubMed - indexed for MEDLINE]Related articles

No major change in vCJD agent strain after secondary transmission via blood transfusion.

Bishop MT, Ritchie DL, Will RG, Ironside JW, Head MW, Thomson V, Bruce M, Manson JC.

PLoS One. 2008 Aug 6;3(8):e2878.PMID: 18682737 [PubMed - indexed for MEDLINE]Related articlesFree article

Biology and neuropathology of prion diseases.

Ironside JW, Head MW.

Handb Clin Neurol. 2008;89:779-97. No abstract available. PMID: 18631794 [PubMed - in process]Related articles

Inter-laboratory assessment of PrPSc typing in creutzfeldt-jakob disease: a Western blot study within the NeuroPrion Consortium.

Parchi P, Notari S, Weber P, Schimmel H, Budka H, Ferrer I, Haik S, Hauw JJ, Head MW, Ironside JW, Limido L, Rodriguez A, Ströbel T, Tagliavini F, Kretzschmar HA.

Brain Pathol. 2009 Jul;19(3):384-91. Epub 2008 Jul 2.PMID: 18624793 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural study of florid plaques in variant Creutzfeldt-Jakob disease: a comparison with amyloid plaques in kuru, sporadic Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease.

Sikorska B, Liberski PP, Sobów T, Budka H, Ironside JW.

Neuropathol Appl Neurobiol. 2009 Feb;35(1):46-59. Epub 2008 May 30.PMID: 18513219 [PubMed - indexed for MEDLINE]Related articles

An antibody to the aggregated synthetic prion protein peptide (PrP106-126) selectively recognizes disease-associated prion protein (PrP) from human brain specimens.

Jones M, Wight D, McLoughlin V, Norrby K, Ironside JW, Connolly JG, Farquhar CF, MacGregor IR, Head MW.

Brain Pathol. 2009 Apr;19(2):293-302. Epub 2008 May 26.PMID: 18507665 [PubMed - indexed for MEDLINE]Related articles

Beyond PrP9res) type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.

Uro-Coste E, Cassard H, Simon S, Lugan S, Bilheude JM, Perret-Liaudet A, Ironside JW, Haik S, Basset-Leobon C, Lacroux C, Peoch' K, Streichenberger N, Langeveld J, Head MW, Grassi J, Hauw JJ, Schelcher F, Delisle MB, Andréoletti O.

PLoS Pathog. 2008 Mar 14;4(3):e1000029.PMID: 18389084 [PubMed - indexed for MEDLINE]Related articlesFree article

Beyond PrP res type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.

Uro-Coste E, Cassard H, Simon S, Lugan S, Bilheude JM, Perret-Liaudet A, Ironside JW, Haik S, Basset-Leobon C, Lacroux C, Peoch K, Streichenberger N, Langeveld J, Head MW, Grassi J, Hauw JJ, Schelcher F, Delisle MB, Andréoletti O.

PLoS Pathog. 2008 Mar;4(3):e1000029.PMID: 18383623 [PubMed - indexed for MEDLINE]Related articles

Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium.

Bell JE, Alafuzoff I, Al-Sarraj S, Arzberger T, Bogdanovic N, Budka H, Dexter DT, Falkai P, Ferrer I, Gelpi E, Gentleman SM, Giaccone G, Huitinga I, Ironside JW, Klioueva N, Kovacs GG, Meyronet D, Palkovits M, Parchi P, Patsouris E, Reynolds R, Riederer P, Roggendorf W, Seilhean D, Schmitt A, Schmitz P, Streichenberger N, Schwalber A, Kretzschmar H.

Acta Neuropathol. 2008 May;115(5):497-507. Epub 2008 Mar 26. Review.PMID: 18365220 [PubMed - indexed for MEDLINE]Related articles

Infective dementias.

Ironside JW, Bell JE.

Panminerva Med. 2007 Dec;49(4):209-25. Review.PMID: 18091673 [PubMed - indexed for MEDLINE]Related articles

Tissue and organ donation for research in forensic pathology: the MRC Sudden Death Brain and Tissue Bank.

Millar T, Walker R, Arango JC, Ironside JW, Harrison DJ, MacIntyre DJ, Blackwood D, Smith C, Bell JE.

J Pathol. 2007 Dec;213(4):369-75.PMID: 17990279 [PubMed - indexed for MEDLINE]Related articles

Disease-associated prion protein is not detectable in human systemic amyloid deposits.

Tennent GA, Head MW, Bishop M, Hawkins PN, Will RG, Knight R, Peden AH, McCardle LM, Ironside JW, Pepys MB.

J Pathol. 2007 Dec;213(4):376-83.PMID: 17955450 [PubMed - indexed for MEDLINE]Related articles

Application of Atomic Dielectric Resonance Spectroscopy for the screening of blood samples from patients with clinical variant and sporadic CJD.

Fagge TJ, Barclay GR, Stove GC, Stove G, Robinson MJ, Head MW, Ironside JW, Turner ML.

J Transl Med. 2007 Aug 30;5:41.PMID: 17760958 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro amplification and detection of variant Creutzfeldt-Jakob disease PrPSc.

Jones M, Peden AH, Prowse CV, Gröner A, Manson JC, Turner ML, Ironside JW, MacGregor IR, Head MW.

J Pathol. 2007 Sep;213(1):21-6.PMID: 17614097 [PubMed - indexed for MEDLINE]Related articles

Sporadic Creutzfeldt-Jakob disease in two adolescents.

Murray K, Ritchie DL, Bruce M, Young CA, Doran M, Ironside JW, Will RG.

J Neurol Neurosurg Psychiatry. 2008 Jan;79(1):14-8. Epub 2007 May 23.PMID: 17522102 [PubMed - indexed for MEDLINE]Related articles

A young man with rapidly progressive multifocal disease affecting the white matter.

Hilton-Jones D, Ironside JW, Simpson DJ.

Pract Neurol. 2007 Jun;7(3):172-81. No abstract available. PMID: 17515596 [PubMed - indexed for MEDLINE]Related articles

The first case of variant Creutzfeldt-Jakob disease in The Netherlands.

Sánchez-Juan P, Houben MP, Hoff JI, Jansen C, Sie MP, van Rijn MJ, Ironside JW, Will RG, van Duijn CM, Rozemuller A.

J Neurol. 2007 Jul;254(7):958-60. Epub 2007 Apr 21. No abstract available. PMID: 17450319 [PubMed - indexed for MEDLINE]Related articles

Nodule formation and desmoplasia in medulloblastomas-defining the nodular/desmoplastic variant and its biological behavior.

McManamy CS, Pears J, Weston CL, Hanzely Z, Ironside JW, Taylor RE, Grundy RG, Clifford SC, Ellison DW; Clinical Brain Tumour Group.

Brain Pathol. 2007 Apr;17(2):151-64.PMID: 17388946 [PubMed - indexed for MEDLINE]Related articles

Abnormal prion protein in the pituitary in sporadic and variant Creutzfeldt-Jakob disease.

Peden AH, Ritchie DL, Uddin HP, Dean AF, Schiller KA, Head MW, Ironside JW.

J Gen Virol. 2007 Mar;88(Pt 3):1068-72.PMID: 17325383 [PubMed - indexed for MEDLINE]Related articlesFree article

vCJD and the gut: implications for endoscopy.

Head MW, Ironside JW.

Gut. 2007 Jan;56(1):9-11. Review. No abstract available. PMID: 17172584 [PubMed - indexed for MEDLINE]Related articles

Primary intracranial angiosarcoma of the Pineal gland: an unusual cause of recurrent intraventricular haemorrhage and superficial haemosiderosis.

Kurian KM, Tagkalakis P, Erridge SC, Ironside JW, Whittle IR.

Neuropathol Appl Neurobiol. 2006 Oct;32(5):557-61. No abstract available. PMID: 16972889 [PubMed - indexed for MEDLINE]Related articles

Transplantation of ocular tissue from a donor with sporadic Creutzfeldt-Jakob disease.

Tullo AB, Buckley RJ, Kelly T, Head MW, Bennett P, Armitage WJ, Ironside JW.

Clin Experiment Ophthalmol. 2006 Sep-Oct;34(7):645-9.PMID: 16970756 [PubMed - indexed for MEDLINE]Related articles

Application of an immunocapillary electrophoresis assay to the detection of abnormal prion protein in brain, spleen and blood specimens from patients with variant Creutzfeldt-Jakob disease.

Lourenco PC, Schmerr MJ, MacGregor I, Will RG, Ironside JW, Head MW.

J Gen Virol. 2006 Oct;87(Pt 10):3119-24.PMID: 16963772 [PubMed - indexed for MEDLINE]Related articlesFree article

Sporadic Creutzfeldt-Jakob disease: further twists and turns in a convoluted protein.

Head MW, Ironside JW.

Brain. 2006 Sep;129(Pt 9):2238-40. No abstract available. PMID: 16923953 [PubMed - indexed for MEDLINE]Related articlesFree article

An outline of the neuropathology of transmissible spongiform encephalopathies (prion diseases).

Liberski PP, Ironside JW.

Folia Neuropathol. 2004;42 Suppl B:39-58. Review.PMID: 16903141 [PubMed - indexed for MEDLINE]Related articles

Size frequency distributions of the florid prion protein aggregates in variant Creutzfeldt-Jakob disease follow a power-law function.

Armstrong RA, Cairns NJ, Ironside JW.

Neurol Sci. 2006 Jun;27(2):104-9.PMID: 16816906 [PubMed - indexed for MEDLINE]Related articles

Clusterin expression in follicular dendritic cells associated with prion protein accumulation.

Sasaki K, Doh-ura K, Ironside J, Mabbott N, Iwaki T.

J Pathol. 2006 Aug;209(4):484-91.PMID: 16767691 [PubMed - indexed for MEDLINE]Related articles

An intramedullary vascular malformation mimicking intrinsic spinal cord tumour.

Peng EW, Kurian KM, Ironside JW, Macmullen-Price J, Fitzpatrick MO, Whittle IR.

Br J Neurosurg. 2006 Apr;20(2):109-10. No abstract available. PMID: 16753630 [PubMed - indexed for MEDLINE]Related articles

Predicting susceptibility and incubation time of human-to-human transmission of vCJD.

Bishop MT, Hart P, Aitchison L, Baybutt HN, Plinston C, Thomson V, Tuzi NL, Head MW, Ironside JW, Will RG, Manson JC.

Lancet Neurol. 2006 May;5(5):393-8.PMID: 16632309 [PubMed - indexed for MEDLINE]Related articles

Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.

Heath CA, Barker RA, Esmonde TF, Harvey P, Roberts R, Trend P, Head MW, Smith C, Bell JE, Ironside JW, Will RG, Knight RS.

J Neurol Neurosurg Psychiatry. 2006 Jul;77(7):880-2. Epub 2006 Apr 20.PMID: 16627534 [PubMed - indexed for MEDLINE]Related articlesFree article

Variant Creutzfeldt-Jakob disease: prion protein genotype analysis of positive appendix tissue samples from a retrospective prevalence study.

Ironside JW, Bishop MT, Connolly K, Hegazy D, Lowrie S, Le Grice M, Ritchie DL, McCardle LM, Hilton DA.

BMJ. 2006 May 20;332(7551):1186-8. Epub 2006 Apr 10. Erratum in: BMJ. 2006 Aug 26;333(7565):416. PMID: 16606639 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease.

Peden AH, Ritchie DL, Head MW, Ironside JW.

Am J Pathol. 2006 Mar;168(3):927-35.PMID: 16507908 [PubMed - indexed for MEDLINE]Related articlesFree article

vCJD prion acquires altered virulence through trans-species infection.

Asano M, Mohri S, Ironside JW, Ito M, Tamaoki N, Kitamoto T.

Biochem Biophys Res Commun. 2006 Mar 31;342(1):293-9. Epub 2006 Feb 7.PMID: 16480953 [PubMed - indexed for MEDLINE]Related articles