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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 2
2001 3
2002 3
2003 8
2004 3
2005 5
2006 4
2007 6
2008 5
2009 8
2010 11
2011 5
2012 18
2013 13
2014 36
2015 43
2016 51
2017 64
2018 76
2019 122
2020 163
2021 183
2022 215
2023 216
2024 120

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1,156 results

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Page 1
Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis.
Wang Y, Ye Z, Ge L, Siemieniuk RAC, Wang X, Wang Y, Hou L, Ma Z, Agoritsas T, Vandvik PO, Perner A, Møller MH, Guyatt GH, Liu L. Wang Y, et al. BMJ. 2020 Jan 6;368:l6744. doi: 10.1136/bmj.l6744. BMJ. 2020. PMID: 31907166 Free PMC article.
OBJECTIVE: To determine, in critically ill patients, the relative impact of proton pump inhibitors (PPIs), histamine-2 receptor antagonists (H2RAs), sucralfate, or no gastrointestinal bleeding prophylaxis (or stress ulcer prophylaxis) on outcomes important to patients. ... …
OBJECTIVE: To determine, in critically ill patients, the relative impact of proton pump inhibitors (PPIs), histamine-2 receptor antagonists …
Association of Antisecretory Drugs with Upper Gastrointestinal Bleeding in Patients Using Oral Anticoagulants: A Systematic Review and Meta-Analysis.
Kurlander JE, Barnes GD, Fisher A, Gonzalez JJ, Helminski D, Saini SD, Sengupta N, Yang YX, Scheiman J, Laine L. Kurlander JE, et al. Am J Med. 2022 Oct;135(10):1231-1243.e8. doi: 10.1016/j.amjmed.2022.05.031. Epub 2022 Jun 7. Am J Med. 2022. PMID: 35679879 Free PMC article.
Individual studies showed greater treatment effect in patients with higher risk for upper gastrointestinal bleeding (eg, nonsteroidal anti-inflammatory drug or aspirin use, elevated bleeding risk score). ...CONCLUSIONS: Evidence drawn mostly from observational studi …
Individual studies showed greater treatment effect in patients with higher risk for upper gastrointestinal bleeding (eg, nonsteroidal …
Systemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis.
Marti C, John G, Konstantinides S, Combescure C, Sanchez O, Lankeit M, Meyer G, Perrier A. Marti C, et al. Eur Heart J. 2015 Mar 7;36(10):605-14. doi: 10.1093/eurheartj/ehu218. Epub 2014 Jun 10. Eur Heart J. 2015. PMID: 24917641 Free PMC article. Review.
Major haemorrhage (OR; 2.91, 95% CI: 1.95-4.36) and fatal or intracranial bleeding (OR: 3.18, 95% CI: 1.25-8.11) were significantly more frequent among patients receiving thrombolysis. ...
Major haemorrhage (OR; 2.91, 95% CI: 1.95-4.36) and fatal or intracranial bleeding (OR: 3.18, 95% CI: 1.25-8.11) were significantly m …
Recurrence Rates and Pharmacological Treatment for Hemorrhoidal Disease: A Systematic Review.
Lohsiriwat V, Sheikh P, Bandolon R, Ren DL, Roslani AC, Schaible K, Freitag A, Martin M, Yaltirik P, Godeberge P. Lohsiriwat V, et al. Adv Ther. 2023 Jan;40(1):117-132. doi: 10.1007/s12325-022-02351-7. Epub 2022 Nov 4. Adv Ther. 2023. PMID: 36331754 Free PMC article. Review.
INTRODUCTION: Hemorrhoidal disease (HD) is characterized by prolapse of the inflamed and bleeding vascular tissues of the anal canal. Although HD is associated with a high recurrence rate, there is a lack of understanding around interventions that can reduce recurrence and …
INTRODUCTION: Hemorrhoidal disease (HD) is characterized by prolapse of the inflamed and bleeding vascular tissues of the anal canal. …
Preventing postpartum hemorrhage after cesarean delivery: a network meta-analysis of available pharmacologic agents.
Jaffer D, Singh PM, Aslam A, Cahill AG, Palanisamy A, Monks DT. Jaffer D, et al. Am J Obstet Gynecol. 2022 Mar;226(3):347-365. doi: 10.1016/j.ajog.2021.08.060. Epub 2021 Sep 14. Am J Obstet Gynecol. 2022. PMID: 34534498 Review.
BACKGROUND: Postpartum hemorrhage causes a quarter of global maternal deaths. The World Health Organization recommends oxytocin as the first line agent to prevent hemorrhage during cesarean delivery. ...Our primary outcomes were the estimated blood loss and need for …
BACKGROUND: Postpartum hemorrhage causes a quarter of global maternal deaths. The World Health Organization recommends oxytocin as th …
Tranexamic acid for gastrointestinal bleeding: A systematic review with meta-analysis of randomized clinical trials.
Lee PL, Yang KS, Tsai HW, Hou SK, Kang YN, Chang CC. Lee PL, et al. Am J Emerg Med. 2021 Jul;45:269-279. doi: 10.1016/j.ajem.2020.08.062. Epub 2020 Aug 29. Am J Emerg Med. 2021. PMID: 33041136
BACKGROUND: Acute gastrointestinal bleeding is a common life-threatening emergent condition. Immediate tranexamic acid is useful for reducing hemorrhage following operation and bleeding trauma, but evidence on the effects of tranexamic acid in patients with g …
BACKGROUND: Acute gastrointestinal bleeding is a common life-threatening emergent condition. Immediate tranexamic acid is useful for …
Effects of Non-Vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: A Systematic Review and Meta-Analysis.
Pan KL, Singer DE, Ovbiagele B, Wu YL, Ahmed MA, Lee M. Pan KL, et al. J Am Heart Assoc. 2017 Jul 18;6(7):e005835. doi: 10.1161/JAHA.117.005835. J Am Heart Assoc. 2017. PMID: 28720644 Free PMC article. Review.
Pooling results from included trials showed that NOACs versus warfarin reduced stroke or systemic embolism (HR: 0.70; 95% CI, 0.60-0.82) and intracranial hemorrhage (HR: 0.47; 95% CI, 0.24-0.92) in AF patients with VHD. However, risk reduction of major bleeding and …
Pooling results from included trials showed that NOACs versus warfarin reduced stroke or systemic embolism (HR: 0.70; 95% CI, 0.60-0.82) and …
Evaluation of Direct Oral Anticoagulant Reversal Agents in Intracranial Hemorrhage: A Systematic Review and Meta-analysis.
Chaudhary R, Singh A, Chaudhary R, Bashline M, Houghton DE, Rabinstein A, Adamski J, Arndt R, Ou NN, Rudis MI, Brown CS, Wieruszewski ED, Wanek M, Brinkman NJ, Linderbaum JA, Sorenson MA, Atkinson JL, Thompson KM, Aiyer AN, McBane RD 2nd. Chaudhary R, et al. JAMA Netw Open. 2022 Nov 1;5(11):e2240145. doi: 10.1001/jamanetworkopen.2022.40145. JAMA Netw Open. 2022. PMID: 36331504 Free PMC article.
IMPORTANCE: Direct oral anticoagulant (DOAC)-associated intracranial hemorrhage (ICH) has high morbidity and mortality. The safety and outcome data of DOAC reversal agents in ICH are limited. ...
IMPORTANCE: Direct oral anticoagulant (DOAC)-associated intracranial hemorrhage (ICH) has high morbidity and mortality. The safety an …
1,156 results