PubMed

A homogeneous HLA-B*27 genotyping assay using dried reagent mixtures.

Kiviniemi M, Ilonen J, Lövgren T.

Dis Markers. 2009;27(2):85-91.PMID: 19893203 [PubMed - in process]Related articles

The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations.

Jermendy A, Szatmári I, Laine AP, Lukács K, Horváth KH, Körner A, Madácsy L, Veijola R, Simell O, Knip M, Ilonen J, Hermann R; The Finnish Paediatric Diabetes Registry; The HUNT1DGENES Programme.

Diabetologia. 2009 Oct 20. [Epub ahead of print]PMID: 19841890 [PubMed - as supplied by publisher]Related articles

Predictive characteristics of diabetes-associated autoantibodies among children with HLA-conferred disease susceptibility in the general population.

Siljander HT, Simell S, Hekkala A, Lähde J, Simell T, Vähäsalo P, Veijola R, Ilonen J, Simell O, Knip M.

Diabetes. 2009 Dec;58(12):2835-42. Epub 2009 Sep 15.PMID: 19755526 [PubMed - in process]Related articles

Early introduction of oats associated with decreased risk of persistent asthma and early introduction of fish with decreased risk of allergic rhinitis.

Virtanen SM, Kaila M, Pekkanen J, Kenward MG, Uusitalo U, Pietinen P, Kronberg-Kippilä C, Hakulinen T, Simell O, Ilonen J, Veijola R, Knip M.

Br J Nutr. 2009 Aug 13:1-8. [Epub ahead of print]PMID: 19674492 [PubMed - as supplied by publisher]Related articles

Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility.

Siljander H, Härkönen T, Hermann R, Simell S, Hekkala A, Salonsaari RT, Simell T, Simell O, Ilonen J, Veijola R, Knip M.

Diabetes Metab Res Rev. 2009 Oct;25(7):615-22.PMID: 19637309 [PubMed - in process]Related articles

Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children.

Erkkola M, Kaila M, Nwaru BI, Kronberg-Kippilä C, Ahonen S, Nevalainen J, Veijola R, Pekkanen J, Ilonen J, Simell O, Knip M, Virtanen SM.

Clin Exp Allergy. 2009 Jun;39(6):875-82.PMID: 19522996 [PubMed - indexed for MEDLINE]Related articles

Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes.

Lempainen J, Vaarala O, Mäkelä M, Veijola R, Simell O, Knip M, Hermann R, Ilonen J.

J Autoimmun. 2009 Sep;33(2):155-64. Epub 2009 May 26.PMID: 19473815 [PubMed - indexed for MEDLINE]Related articles

Association of CTLA4 but not ICOS polymorphisms with type 1 diabetes in two populations with different disease rates.

Douroudis K, Laine AP, Heinonen M, Hermann R, Lipponen K, Veijola R, Simell O, Knip M, Uibo R, Ilonen J, Kisand K.

Hum Immunol. 2009 Jul;70(7):536-9. Epub 2009 Apr 17.PMID: 19376178 [PubMed - indexed for MEDLINE]Related articles

HLA-DR-DQ haplotypes and type 1 diabetes in Macedonia.

Ilonen J, Kocova M, Lipponen K, Sukarova-Angelovska E, Jovanovska A, Knip M.

Hum Immunol. 2009 Jun;70(6):461-3. Epub 2009 Mar 27.PMID: 19332095 [PubMed - indexed for MEDLINE]Related articles

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes.

Oresic M, Simell S, Sysi-Aho M, Näntö-Salonen K, Seppänen-Laakso T, Parikka V, Katajamaa M, Hekkala A, Mattila I, Keskinen P, Yetukuri L, Reinikainen A, Lähde J, Suortti T, Hakalax J, Simell T, Hyöty H, Veijola R, Ilonen J, Lahesmaa R, Knip M, Simell O.

J Exp Med. 2008 Dec 22;205(13):2975-84. Epub 2008 Dec 15.PMID: 19075291 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipopolysaccharide-induced immune responses in relation to the TLR4(Asp299Gly) gene polymorphism.

Lundberg A, Wikberg LA, Ilonen J, Vaarala O, Böttcher MF.

Clin Vaccine Immunol. 2008 Dec;15(12):1878-83. Epub 2008 Oct 15.PMID: 18927069 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of parental type 2 diabetes on offspring with type 1 diabetes.

Thorn LM, Forsblom C, Wadén J, Söderlund J, Rosengård-Bärlund M, Saraheimo M, Heikkilä O, Hietala K, Pettersson-Fernholm K, Ilonen J, Groop PH; FinnDiane Study Group.

Diabetes Care. 2009 Jan;32(1):63-8. Epub 2008 Oct 3.PMID: 18835950 [PubMed - in process]Related articlesFree article

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial.

Näntö-Salonen K, Kupila A, Simell S, Siljander H, Salonsaari T, Hekkala A, Korhonen S, Erkkola R, Sipilä JI, Haavisto L, Siltala M, Tuominen J, Hakalax J, Hyöty H, Ilonen J, Veijola R, Simell T, Knip M, Simell O.

Lancet. 2008 Nov 15;372(9651):1746-55. Epub 2008 Sep 22.PMID: 18814906 [PubMed - indexed for MEDLINE]Related articles

Effect of HLA genotype or CTLA-4 polymorphism on cytokine response in healthy children.

Walldén J, Ilonen J, Roivainen M, Ludvigsson J, Vaarala O; ABIS Study Group.

Scand J Immunol. 2008 Sep;68(3):345-50.PMID: 18782261 [PubMed - indexed for MEDLINE]Related articles

Analysis of pancreas tissue in a child positive for islet cell antibodies.

Oikarinen M, Tauriainen S, Honkanen T, Vuori K, Karhunen P, Vasama-Nolvi C, Oikarinen S, Verbeke C, Blair GE, Rantala I, Ilonen J, Simell O, Knip M, Hyöty H.

Diabetologia. 2008 Oct;51(10):1796-802. Epub 2008 Aug 12.PMID: 18696046 [PubMed - indexed for MEDLINE]Related articles

Intake of antioxidant vitamins and trace elements during pregnancy and risk of advanced beta cell autoimmunity in the child.

Uusitalo L, Kenward MG, Virtanen SM, Uusitalo U, Nevalainen J, Niinistö S, Kronberg-Kippilä C, Ovaskainen ML, Marjamäki L, Simell O, Ilonen J, Veijola R, Knip M.

Am J Clin Nutr. 2008 Aug;88(2):458-64.PMID: 18689383 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the humoral immune response to islet antigen 2 in children with newly diagnosed type 1 diabetes.

Mäkinen A, Härkönen T, Ilonen J, Knip M; Finnish Pediatric Diabetes Register.

Eur J Endocrinol. 2008 Jul;159(1):19-26.PMID: 18573919 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies.

Marttila J, Huttunen S, Vaarala O, Suzuki K, Elliott JF, Närvänen A, Knip M, Simell O, Ilonen J.

J Autoimmun. 2008 Sep;31(2):142-8. Epub 2008 Jun 18.PMID: 18565729 [PubMed - indexed for MEDLINE]Related articles

Enhanced levels of cow's milk antibodies in infancy in children who develop type 1 diabetes later in childhood.

Luopajärvi K, Savilahti E, Virtanen SM, Ilonen J, Knip M, Akerblom HK, Vaarala O.

Pediatr Diabetes. 2008 Oct;9(5):434-41. Epub 2008 May 21.PMID: 18503496 [PubMed - indexed for MEDLINE]Related articles

Temporal relationship between human parechovirus 1 infection and otitis media in young children.

Tauriainen S, Oikarinen S, Taimen K, Laranne J, Sipilä M, Lönnrot M, Ilonen J, Simell O, Knip M, Hyöty H.

J Infect Dis. 2008 Jul 1;198(1):35-40.PMID: 18462136 [PubMed - indexed for MEDLINE]Related articles

Lower economic status and inferior hygienic environment may protect against celiac disease.

Kondrashova A, Mustalahti K, Kaukinen K, Viskari H, Volodicheva V, Haapala AM, Ilonen J, Knip M, Mäki M, Hyöty H; Epivir Study Group.

Ann Med. 2008;40(3):223-31.PMID: 18382888 [PubMed - indexed for MEDLINE]Related articles

Relation among mannose-binding lectin 2 genotype, beta-cell autoantibodies, and risk for type 1 diabetes in Finnish children.

Aittoniemi J, Turpeinen H, Tiittanen M, Knip M, Simell O, Ilonen J, Vaarala O.

Hum Immunol. 2008 Feb;69(2):108-11. Epub 2008 Feb 20.PMID: 18361935 [PubMed - indexed for MEDLINE]Related articles

Human leucocyte antigen and TNFalpha polymorphism association in microscopic colitis.

Koskela RM, Karttunen TJ, Niemelä SE, Lehtola JK, Ilonen J, Karttunen RA.

Eur J Gastroenterol Hepatol. 2008 Apr;20(4):276-82.PMID: 18334870 [PubMed - indexed for MEDLINE]Related articles

Progression to type 1 diabetes and autoantibody positivity in relation to HLA-risk genotypes in children participating in the ABIS study.

Gullstrand C, Wahlberg J, Ilonen J, Vaarala O, Ludvigsson J.

Pediatr Diabetes. 2008 Jun;9(3 Pt 1):182-90. Epub 2008 Mar 5.PMID: 18331414 [PubMed - indexed for MEDLINE]Related articles

Serum alpha- and gamma-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus.

Uusitalo L, Nevalainen J, Niinistö S, Alfthan G, Sundvall J, Korhonen T, Kenward MG, Oja H, Veijola R, Simell O, Ilonen J, Knip M, Virtanen SM.

Diabetologia. 2008 May;51(5):773-80. Epub 2008 Mar 4.PMID: 18317723 [PubMed - indexed for MEDLINE]Related articles

Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant.

Aarnisalo J, Treszl A, Svec P, Marttila J, Oling V, Simell O, Knip M, Körner A, Madacsy L, Vasarhelyi B, Ilonen J, Hermann R.

J Autoimmun. 2008 Aug;31(1):13-21. Epub 2008 Mar 4.PMID: 18299186 [PubMed - indexed for MEDLINE]Related articles

Cytomegalovirus infection in early infancy: risk of induction and progression of autoimmunity associated with type 1 diabetes.

Aarnisalo J, Veijola R, Vainionpää R, Simell O, Knip M, Ilonen J.

Diabetologia. 2008 May;51(5):769-72. Epub 2008 Feb 16.PMID: 18278478 [PubMed - indexed for MEDLINE]Related articles

Image feature localization by multiple hypothesis testing of Gabor features.

Ilonen J, Kamarainen JK, Paalanen P, Hamouz M, Kittler J, Kälviäinen H.

IEEE Trans Image Process. 2008 Mar;17(3):311-25.PMID: 18270121 [PubMed - indexed for MEDLINE]Related articles

MxA protein assay for optimal monitoring of IFN-beta bioactivity in the treatment of MS patients.

Vallittu AM, Erälinna JP, Ilonen J, Salmi AA, Waris M.

Acta Neurol Scand. 2008 Jul;118(1):12-7. Epub 2007 Dec 13.PMID: 18081914 [PubMed - indexed for MEDLINE]Related articles

Serological evidence of thyroid autoimmunity among schoolchildren in two different socioeconomic environments.

Kondrashova A, Viskari H, Haapala AM, Seiskari T, Kulmala P, Ilonen J, Knip M, Hyöty H.

J Clin Endocrinol Metab. 2008 Mar;93(3):729-34. Epub 2007 Dec 11.PMID: 18073310 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of extended human leukocyte antigen haplotype association with Addison's disease in three populations.

Gombos Z, Hermann R, Kiviniemi M, Nejentsev S, Reimand K, Fadeyev V, Peterson P, Uibo R, Ilonen J.

Eur J Endocrinol. 2007 Dec;157(6):757-61.PMID: 18057383 [PubMed - indexed for MEDLINE]Related articlesFree article

A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: an application for the TEDDY (the Environmental Determinants of Diabetes in the Young) study.

Kiviniemi M, Hermann R, Nurmi J, Ziegler AG, Knip M, Simell O, Veijola R, Lövgren T, Ilonen J; TEDDY Study Group.

Diabetes Technol Ther. 2007 Oct;9(5):460-72.PMID: 17931054 [PubMed - indexed for MEDLINE]Related articles

Puumala virus RNA in cerebrospinal fluid in a patient with uncomplicated nephropathia epidemica.

Mähönen SM, Sironen T, Vapalahti O, Pääkkö E, Hautala N, Ilonen J, Glumoff V, Vainio O, Kauma H, Vaheri A, Plyusnin A, Hautala T.

J Clin Virol. 2007 Nov;40(3):248-51. Epub 2007 Sep 27. No abstract available. PMID: 17900974 [PubMed - indexed for MEDLINE]Related articles

Circulating CD4+CD25 high regulatory T cells and natural killer T cells in children with newly diagnosed type 1 diabetes or with diabetes-associated autoantibodies.

Oling V, Marttila J, Knip M, Simell O, Ilonen J.

Ann N Y Acad Sci. 2007 Jun;1107:363-72.PMID: 17804564 [PubMed - indexed for MEDLINE]Related articles

Antibody responses to deamidated gliadin peptide show high specificity and parallel antibodies to tissue transglutaminase in developing coeliac disease.

Ankelo M, Kleimola V, Simell S, Simell O, Knip M, Jokisalo E, Tarkia M, Westerlund A, He Q, Viander M, Ilonen J, Hinkkanen AE.

Clin Exp Immunol. 2007 Nov;150(2):285-93. Epub 2007 Sep 4.PMID: 17803713 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis.

Thomson G, Valdes AM, Noble JA, Kockum I, Grote MN, Najman J, Erlich HA, Cucca F, Pugliese A, Steenkiste A, Dorman JS, Caillat-Zucman S, Hermann R, Ilonen J, Lambert AP, Bingley PJ, Gillespie KM, Lernmark A, Sanjeevi CB, Rønningen KS, Undlien DE, Thorsby E, Petrone A, Buzzetti R, Koeleman BP, Roep BO, Saruhan-Direskeneli G, Uyar FA, Günoz H, Gorodezky C, Alaez C, Boehm BO, Mlynarski W, Ikegami H, Berrino M, Fasano ME, Dametto E, Israel S, Brautbar C, Santiago-Cortes A, Frazer de Llado T, She JX, Bugawan TL, Rotter JI, Raffel L, Zeidler A, Leyva-Cobian F, Hawkins BR, Chan SH, Castano L, Pociot F, Nerup J.

Tissue Antigens. 2007 Aug;70(2):110-27.PMID: 17610416 [PubMed - indexed for MEDLINE]Related articles

Fate of five celiac disease-associated antibodies during normal diet in genetically at-risk children observed from birth in a natural history study.

Simell S, Hoppu S, Hekkala A, Simell T, Ståhlberg MR, Viander M, Yrjänäinen H, Grönlund J, Markula P, Simell V, Knip M, Ilonen J, Hyöty H, Simell O.

Am J Gastroenterol. 2007 Sep;102(9):2026-35. Epub 2007 Jun 15.PMID: 17573785 [PubMed - indexed for MEDLINE]Related articles

Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations.

Laine AP, Holmberg H, Nilsson A, Ortqvist E, Kiviniemi M, Vaarala O, Akerblom HK, Simell O, Knip M, Ludvigsson J, Ivarsson SA, Larsson K, Lernmark A, Ilonen J; Finnish Paediatric Diabetes Registry.

Dis Markers. 2007;23(3):139-45.PMID: 17473382 [PubMed - indexed for MEDLINE]Related articlesFree article

Human parechovirus 1 infections in young children--no association with type 1 diabetes.

Tauriainen S, Martiskainen M, Oikarinen S, Lönnrot M, Viskari H, Ilonen J, Simell O, Knip M, Hyöty H.

J Med Virol. 2007 Apr;79(4):457-62.PMID: 17311340 [PubMed - indexed for MEDLINE]Related articles

Affinity maturation of immunoglobulin A anti-tissue transglutaminase autoantibodies during development of coeliac disease.

Westerlund A, Ankelo M, Simell S, Ilonen J, Knip M, Simell O, Hinkkanen AE.

Clin Exp Immunol. 2007 May;148(2):230-40. Epub 2007 Feb 7.PMID: 17286799 [PubMed - indexed for MEDLINE]Related articlesFree article

Time-resolved immunofluorometric dual-label assay for simultaneous detection of autoantibodies to GAD65 and IA-2 in children with type 1 diabetes.

Ankelo M, Westerlund A, Blomberg K, Knip M, Ilonen J, Hinkkanen AE.

Clin Chem. 2007 Mar;53(3):472-9. Epub 2007 Jan 26.PMID: 17259239 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced CCR4, interleukin-13 and GATA-3 up-regulation in response to type 2 cytokines of cord blood T lymphocytes in infants at genetic risk of type 1 diabetes.

Luopajärvi K, Skarsvik S, Ilonen J, Akerblom HK, Vaarala O.

Immunology. 2007 Jun;121(2):189-96. Epub 2007 Jan 18.PMID: 17244154 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of tumour necrosis factor a, b and c microsatellite polymorphisms with clinical disease activity and induction of remission in early rheumatoid arthritis.

Laivoranta-Nyman S, Möttönen T, Hannonen P, Korpela M, Kautiainen H, Leirisalo-Repo M, Julkunen H, Luukkainen R, Hakala M, Vuori K, Laine AP, Toivanen A, Ilonen J; FIN-RACo Trial Group.

Clin Exp Rheumatol. 2006 Nov-Dec;24(6):636-42.PMID: 17207378 [PubMed - indexed for MEDLINE]Related articles

Signs of beta-cell autoimmunity in nondiabetic schoolchildren: a comparison between Russian Karelia with a low incidence of type 1 diabetes and Finland with a high incidence rate.

Kondrashova A, Viskari H, Kulmala P, Romanov A, Ilonen J, Hyöty H, Knip M.

Diabetes Care. 2007 Jan;30(1):95-100.PMID: 17192340 [PubMed - indexed for MEDLINE]Related articlesFree article

Probiotics for the prevention of beta cell autoimmunity in children at genetic risk of type 1 diabetes--the PRODIA study.

Ljungberg M, Korpela R, Ilonen J, Ludvigsson J, Vaarala O.

Ann N Y Acad Sci. 2006 Oct;1079:360-4.PMID: 17130579 [PubMed - indexed for MEDLINE]Related articles

Time-resolved fluorescence imaging of islet cell autoantibodies.

Vuorinen P, Rulli M, Kuusisto A, Simell S, Simell T, Vahlberg T, Ilonen J, Hyöty H, Knip M, Simell O.

Ann N Y Acad Sci. 2006 Oct;1079:226-8.PMID: 17130559 [PubMed - indexed for MEDLINE]Related articles

Parental reactions to information about increased genetic risk of type 1 diabetes mellitus in infants.

Simonen P, Korhonen T, Simell T, Keskinen P, Kärkkäinen M, Knip M, Ilonen J, Simell O.

Arch Pediatr Adolesc Med. 2006 Nov;160(11):1131-6.PMID: 17088516 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of MxA protein in blood lymphocytes of children receiving anticancer chemotherapy.

Koskenvuo MM, Halminen M, Blomqvist M, Vainionpää R, Ilonen J, Julkunen I, Salmi TT, Mäkelä MJ.

Pediatr Hematol Oncol. 2006 Dec;23(8):649-60.PMID: 17065141 [PubMed - indexed for MEDLINE]Related articles

Dietary insulin as an immunogen and tolerogen.

Tiittanen M, Paronen J, Savilahti E, Virtanen SM, Ilonen J, Knip M, Akerblom HK, Vaarala O; Finnish TRIGR Study Group.

Pediatr Allergy Immunol. 2006 Nov;17(7):538-43.PMID: 17014631 [PubMed - indexed for MEDLINE]Related articles

Human leukocyte antigen non-class II determinants for type 1 diabetes in the Finnish population.

Gombos Z, Wachowicz J, Veijola R, Akerblom HK, Simell O, Knip M, Ilonen J, Hermann R.

Hum Immunol. 2006 Sep;67(9):714-21. Epub 2006 Jun 22.PMID: 17002902 [PubMed - indexed for MEDLINE]Related articles