PubMed

Therapeutic angiogenesis in diabetic apolipoprotein E-deficient mice using bone marrow cells, functional hemangioblasts and metabolic intervention.

Balestrieri ML, Lu SJ, de Nigris F, Giovane A, Williams-Ignarro S, D'Armiento FP, Feng Q, Fiorito C, Testa G, Pastore L, Cacciatore F, Mancini FP, Servillo L, De Rosa G, Pagliarulo C, Rienzo M, Minucci PB, Farzati B, Salvatore F, Rengo F, Ignarro LJ, Giordano A, Baker A, Lanza R, Napoli C.

Atherosclerosis. 2009 Oct 29. [Epub ahead of print]PMID: 19932479 [PubMed - as supplied by publisher]Related articles

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases.

Napoli C, Ignarro LJ.

Arch Pharm Res. 2009 Aug;32(8):1103-8. Epub 2009 Aug 29. Review.PMID: 19727602 [PubMed - indexed for MEDLINE]Related articles

Preface to this special journal issue on nitric oxide chemistry and biology.

Ignarro LJ.

Arch Pharm Res. 2009 Aug;32(8):1099-101. No abstract available. PMID: 19727601 [PubMed - indexed for MEDLINE]Related articles

Evidence-based use of pulsed electromagnetic field therapy in clinical plastic surgery.

Strauch B, Herman C, Dabb R, Ignarro LJ, Pilla AA.

Aesthet Surg J. 2009 Mar-Apr;29(2):135-43. Review.PMID: 19371845 [PubMed - indexed for MEDLINE]Related articles

Mechanisms by which exercise training benefits patients with heart failure.

Crimi E, Ignarro LJ, Cacciatore F, Napoli C.

Nat Rev Cardiol. 2009 Apr;6(4):292-300. Review.PMID: 19352333 [PubMed - indexed for MEDLINE]Related articles

Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation.

d'Emmanuele di Villa Bianca R, Sorrentino R, Maffia P, Mirone V, Imbimbo C, Fusco F, De Palma R, Ignarro LJ, Cirino G.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4513-8. Epub 2009 Mar 2.PMID: 19255435 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension.

Napoli C, Bruzzese G, Ignarro LJ, Crimi E, de Nigris F, Williams-Ignarro S, Libardi S, Sommese L, Fiorito C, Mancini FP, Cacciatore F, Liguori A.

Am Heart J. 2008 Dec;156(6):1154.e1-8.PMID: 19033012 [PubMed - indexed for MEDLINE]Related articles

Detrimental effects of Bartonella henselae are counteracted by L-arginine and nitric oxide in human endothelial progenitor cells.

Salvatore P, Casamassimi A, Sommese L, Fiorito C, Ciccodicola A, Rossiello R, Avallone B, Grimaldi V, Costa V, Rienzo M, Colicchio R, Williams-Ignarro S, Pagliarulo C, Prudente ME, Abbondanza C, Lamberti F, Baroni A, Buommino E, Farzati B, Tufano MA, Ignarro LJ, Napoli C.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9427-32. Epub 2008 Jun 30.PMID: 18595894 [PubMed - indexed for MEDLINE]Related articlesFree article

Different pharmacological properties of two enantiomers in a unique beta-blocker, nebivolol.

Ignarro LJ.

Cardiovasc Ther. 2008 Summer;26(2):115-34.PMID: 18485134 [PubMed - indexed for MEDLINE]Related articles

Therapeutic dose of nebivolol, a nitric oxide-releasing beta-blocker, reduces atherosclerosis in cholesterol-fed rabbits.

de Nigris F, Mancini FP, Balestrieri ML, Byrns R, Fiorito C, Williams-Ignarro S, Palagiano A, Crimi E, Ignarro LJ, Napoli C.

Nitric Oxide. 2008 Aug;19(1):57-63. Epub 2008 Apr 4.PMID: 18435936 [PubMed - indexed for MEDLINE]Related articles

Therapeutic targeting of the stem cell niche in experimental hindlimb ischemia.

Napoli C, William-Ignarro S, Byrns R, Balestrieri ML, Crimi E, Farzati B, Mancini FP, de Nigris F, Matarazzo A, D'Amora M, Abbondanza C, Fiorito C, Giovane A, Florio A, Varricchio E, Palagiano A, Minucci PB, Tecce MF, Giordano A, Pavan A, Ignarro LJ.

Nat Clin Pract Cardiovasc Med. 2008 Sep;5(9):571-9. Epub 2008 Apr 15.PMID: 18414452 [PubMed - indexed for MEDLINE]Related articles

IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells.

Wei LH, Yang Y, Wu G, Ignarro LJ.

Am J Physiol Cell Physiol. 2008 May;294(5):C1198-205. Epub 2008 Mar 26.PMID: 18367589 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis.

de Nigris F, Rossiello R, Schiano C, Arra C, Williams-Ignarro S, Barbieri A, Lanza A, Balestrieri A, Giuliano MT, Ignarro LJ, Napoli C.

Cancer Res. 2008 Mar 15;68(6):1797-808.PMID: 18339860 [PubMed - indexed for MEDLINE]Related articlesFree article

NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols.

Bratasz A, Selvendiran K, Wasowicz T, Bobko A, Khramtsov VV, Ignarro LJ, Kuppusamy P.

J Transl Med. 2008 Feb 26;6:9.PMID: 18302761 [PubMed - indexed for MEDLINE]Related articlesFree article

NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts.

Selvendiran K, Bratasz A, Tong L, Ignarro LJ, Kuppusamy P.

Cell Cycle. 2008 Jan 1;7(1):81-8. Epub 2007 Sep 28.PMID: 18196976 [PubMed - indexed for MEDLINE]Related articles

Functional impairment of hematopoietic progenitor cells in patients with coronary heart disease.

Liguori A, Fiorito C, Balestrieri ML, Crimi E, Bruzzese G, Williams-Ignarro S, D'Amora M, Sommese L, Grimaldi V, Minucci PB, Giovane A, Farzati B, Ignarro LJ, Napoli C.

Eur J Haematol. 2008 Mar;80(3):258-64. Epub 2007 Dec 7.PMID: 18081701 [PubMed - indexed for MEDLINE]Related articles

Microcirculation and oxidative stress.

Crimi E, Ignarro LJ, Napoli C.

Free Radic Res. 2007 Dec;41(12):1364-75. Review.PMID: 18075839 [PubMed - indexed for MEDLINE]Related articles

Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS pathways.

de Nigris F, Balestrieri ML, Williams-Ignarro S, D'Armiento FP, Lerman LO, Byrns R, Crimi E, Palagiano A, Fatigati G, Ignarro LJ, Napoli C.

J Cardiovasc Pharmacol. 2007 Oct;50(4):424-33.PMID: 18049311 [PubMed - indexed for MEDLINE]Related articles

Therapeutic approaches in vascular repair induced by adult bone marrow cells and circulating progenitor endothelial cells.

Napoli C, Balestrieri A, Ignarro LJ.

Curr Pharm Des. 2007;13(31):3245-51. Review.PMID: 18045174 [PubMed - indexed for MEDLINE]Related articles

Effect of gestational hypercholesterolaemia on omental vasoreactivity, placental enzyme activity and transplacental passage of normal and oxidised fatty acids.

Liguori A, D'Armiento FP, Palagiano A, Balestrieri ML, Williams-Ignarro S, de Nigris F, Lerman LO, D'Amora M, Rienzo M, Fiorito C, Ignarro LJ, Palinski W, Napoli C.

BJOG. 2007 Dec;114(12):1547-56. Epub 2007 Sep 27.PMID: 17903226 [PubMed - indexed for MEDLINE]Related articles

Heart mtNOS, a key mediator of oxidative injury in ischemia/reperfusion.

Ignarro LJ.

J Mol Cell Cardiol. 2007 Oct;43(4):409-10. Epub 2007 Jul 24. No abstract available. PMID: 17764688 [PubMed - indexed for MEDLINE]Related articles

Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.

Parinandi NL, Sharma A, Eubank TD, Kaufman BF, Kutala VK, Marsh CB, Ignarro LJ, Kuppusamy P.

Antioxid Redox Signal. 2007 Nov;9(11):1837-49.PMID: 17760507 [PubMed - indexed for MEDLINE]Related articles

Bone marrow cell-mediated cardiovascular repair: potential of combined therapies.

Napoli C, Maione C, Schiano C, Fiorito C, Ignarro LJ.

Trends Mol Med. 2007 Jul;13(7):278-86. Epub 2007 Jun 15.PMID: 17574919 [PubMed - indexed for MEDLINE]Related articles

The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats.

de Nigris F, Balestrieri ML, Williams-Ignarro S, D'Armiento FP, Fiorito C, Ignarro LJ, Napoli C.

Nitric Oxide. 2007 Aug;17(1):50-4. Epub 2007 May 5.PMID: 17553710 [PubMed - indexed for MEDLINE]Related articles

The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio.

Bode-Böger SM, Scalera F, Ignarro LJ.

Pharmacol Ther. 2007 Jun;114(3):295-306. Epub 2007 Apr 1. Review.PMID: 17482266 [PubMed - indexed for MEDLINE]Related articles

Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia.

Baker AH, Sica V, Work LM, Williams-Ignarro S, de Nigris F, Lerman LO, Casamassimi A, Lanza A, Schiano C, Rienzo M, Ignarro LJ, Napoli C.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3597-602. Epub 2007 Feb 20.PMID: 17360688 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis.

Hayashi T, Juliet PA, Miyazaki A, Ignarro LJ, Iguchi A.

Biochim Biophys Acta. 2007 Mar;1772(3):364-72. Epub 2006 Dec 8.PMID: 17240121 [PubMed - indexed for MEDLINE]Related articles

Low-dose L-arginine administration increases microperfusion of hindlimb muscle without affecting blood pressure in rats.

Ohta F, Takagi T, Sato H, Ignarro LJ.

Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1407-11. Epub 2007 Jan 17.PMID: 17229841 [PubMed - indexed for MEDLINE]Related articlesFree article

Autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the diabetic mouse hindlimb.

Sica V, Williams-Ignarro S, de Nigris F, D'Armiento FP, Lerman LO, Balestrieri ML, Maione C, Palagiano A, Rossiello L, Ignarro LJ, Napoli C.

Cell Cycle. 2006 Dec;5(24):2903-8. Epub 2006 Dec 15.PMID: 17172874 [PubMed - indexed for MEDLINE]Related articles

Nutrition and cardiovascular disease: putting a pathogenic framework into focus.

Napoli C, Stanley WC, Ignarro LJ.

Cardiovasc Res. 2007 Jan 15;73(2):253-6. Epub 2006 Nov 29. No abstract available. PMID: 17161832 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes.

Hayashi T, Matsui-Hirai H, Miyazaki-Akita A, Fukatsu A, Funami J, Ding QF, Kamalanathan S, Hattori Y, Ignarro LJ, Iguchi A.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):17018-23. Epub 2006 Oct 30.PMID: 17075048 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis.

de Nigris F, Williams-Ignarro S, Sica V, Lerman LO, D'Armiento FP, Byrns RE, Casamassimi A, Carpentiero D, Schiano C, Sumi D, Fiorito C, Ignarro LJ, Napoli C.

Cardiovasc Res. 2007 Jan 15;73(2):414-23. Epub 2006 Sep 1.PMID: 17014835 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of oxidative stress in experimental sepsis and multisystem organ dysfunction.

Crimi E, Sica V, Slutsky AS, Zhang H, Williams-Ignarro S, Ignarro LJ, Napoli C.

Free Radic Res. 2006 Jul;40(7):665-72. Review.PMID: 16983993 [PubMed - indexed for MEDLINE]Related articles

Nutrition, physical activity, and cardiovascular disease: an update.

Ignarro LJ, Balestrieri ML, Napoli C.

Cardiovasc Res. 2007 Jan 15;73(2):326-40. Epub 2006 Jul 21. Review.PMID: 16945357 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide (NO) is a new clinical biomarker of survival in the elderly patients and its efficacy might be nearly equal to albumin.

Osawa M, Hayashi T, Nomura H, Funami J, Miyazaki A, Ignarro LJ, Iguchi A.

Nitric Oxide. 2007 Feb;16(1):157-63. Epub 2006 Jun 21.PMID: 16889997 [PubMed - indexed for MEDLINE]Related articles

Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells.

Rodríguez LV, Alfonso Z, Zhang R, Leung J, Wu B, Ignarro LJ.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12167-72. Epub 2006 Jul 31.PMID: 16880387 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic effects of concurrent autologous bone marrow cell infusion and metabolic intervention in ischemia-induced angiogenesis in the hypercholesterolemic mouse hindlimb.

de Nigris F, Williams-Ignarro S, Sica V, D'Armiento FP, Lerman LO, Byrns RE, Sica G, Fiorito C, Ignarro LJ, Napoli C.

Int J Cardiol. 2007 Apr 25;117(2):238-43. Epub 2006 Jul 27.PMID: 16875745 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in endothelial nitric oxide synthase and carotid artery atherosclerosis.

Napoli C, Ignarro LJ.

J Clin Pathol. 2007 Apr;60(4):341-4. Epub 2006 Jul 12. Review. No abstract available. PMID: 16837626 [PubMed - indexed for MEDLINE]Related articles

D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet.

Buga GM, Frank JS, Mottino GA, Hendizadeh M, Hakhamian A, Tillisch JH, Reddy ST, Navab M, Anantharamaiah GM, Ignarro LJ, Fogelman AM.

J Lipid Res. 2006 Oct;47(10):2148-60. Epub 2006 Jul 11.PMID: 16835442 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice.

Napoli C, Williams-Ignarro S, de Nigris F, Lerman LO, D'Armiento FP, Crimi E, Byrns RE, Casamassimi A, Lanza A, Gombos F, Sica V, Ignarro LJ.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10479-84. Epub 2006 Jun 26.PMID: 16801544 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide and atherosclerosis: an update.

Napoli C, de Nigris F, Williams-Ignarro S, Pignalosa O, Sica V, Ignarro LJ.

Nitric Oxide. 2006 Dec;15(4):265-79. Epub 2006 Apr 15. Review.PMID: 16684613 [PubMed - indexed for MEDLINE]Related articles

Free radical biology and medicine: it's a gas, man!

Pryor WA, Houk KN, Foote CS, Fukuto JM, Ignarro LJ, Squadrito GL, Davies KJ.

Am J Physiol Regul Integr Comp Physiol. 2006 Sep;291(3):R491-511. Epub 2006 Apr 20. Review.PMID: 16627692 [PubMed - indexed for MEDLINE]Related articles

Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide.

Ignarro LJ, Byrns RE, Sumi D, de Nigris F, Napoli C.

Nitric Oxide. 2006 Sep;15(2):93-102. Epub 2006 Apr 19.PMID: 16626982 [PubMed - indexed for MEDLINE]Related articles

Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin.

Bratasz A, Weir NM, Parinandi NL, Zweier JL, Sridhar R, Ignarro LJ, Kuppusamy P.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3914-9. Epub 2006 Feb 23.PMID: 16497833 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of human menopausal gonadotrophin treatment on testicular blood flow and on seminal plasma nitric oxide levels in infertile males.

Matteo M, Cicinelli E, Baldini D, Cho YS, Ignarro LJ, Vitarelli A, Boffoli D, Greco P.

Int J Androl. 2006 Aug;29(4):441-5. Epub 2006 Feb 20.PMID: 16487405 [PubMed - indexed for MEDLINE]Related articles

The role of oxidative stress in adult critical care.

Crimi E, Sica V, Williams-Ignarro S, Zhang H, Slutsky AS, Ignarro LJ, Napoli C.

Free Radic Biol Med. 2006 Feb 1;40(3):398-406. Epub 2005 Nov 18. Review.PMID: 16443154 [PubMed - indexed for MEDLINE]Related articles

Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells.

de Nigris F, Williams-Ignarro S, Botti C, Sica V, Ignarro LJ, Napoli C.

Nitric Oxide. 2006 Nov;15(3):259-63. Epub 2006 Jan 18.PMID: 16413211 [PubMed - indexed for MEDLINE]Related articles

Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.

Napoli C, Williams-Ignarro S, de Nigris F, de Rosa G, Lerman LO, Farzati B, Matarazzo A, Sica G, Botti C, Fiore A, Byrns RE, Sumi D, Sica V, Ignarro LJ.

Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17202-6. Epub 2005 Nov 14.PMID: 16286655 [PubMed - indexed for MEDLINE]Related articlesFree article

l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.

Hayashi T, Juliet PA, Matsui-Hirai H, Miyazaki A, Fukatsu A, Funami J, Iguchi A, Ignarro LJ.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13681-6. Epub 2005 Sep 12.PMID: 16157883 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide.

Ignarro LJ.

Curr Top Med Chem. 2005;5(7):595. No abstract available. PMID: 16101421 [PubMed - indexed for MEDLINE]Related articles