PubMed

Ca(2+), within the physiological concentrations, selectively accelerates Abeta42 fibril formation and not Abeta40 in vitro.

Ahmad A, Muzaffar M, Ingram VM.

Biochim Biophys Acta. 2009 Oct;1794(10):1537-48. Epub 2009 Jul 10.PMID: 19595795 [PubMed - indexed for MEDLINE]Related articles

Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs.

Wang H, Duennwald ML, Roberts BE, Rozeboom LM, Zhang YL, Steele AD, Krishnan R, Su LJ, Griffin D, Mukhopadhyay S, Hennessy EJ, Weigele P, Blanchard BJ, King J, Deniz AA, Buchwald SL, Ingram VM, Lindquist S, Shorter J.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7159-64. Epub 2008 May 14.PMID: 18480256 [PubMed - indexed for MEDLINE]Related articlesFree article

Atomic force microscopy analysis of the Huntington protein nanofibril formation.

Dahlgren PR, Karymov MA, Bankston J, Holden T, Thumfort P, Ingram VM, Lyubchenko YL.

Nanomedicine. 2005 Mar;1(1):52-7.PMID: 17292058 [PubMed - indexed for MEDLINE]Related articles

Stochastic kinetics of intracellular huntingtin aggregate formation.

Colby DW, Cassady JP, Lin GC, Ingram VM, Wittrup KD.

Nat Chem Biol. 2006 Jun;2(6):319-23. Epub 2006 May 14.PMID: 16699519 [PubMed - indexed for MEDLINE]Related articles

Atomic force microscopy analysis of the Huntington protein nanofibril formation.

Dahlgren PR, Karymov MA, Bankston J, Holden T, Thumfort P, Ingram VM, Lyubchenko YL.

Dis Mon. 2005 Jun;51(6):374-85. No abstract available. PMID: 16242522 [PubMed - indexed for MEDLINE]Related articles

The role of Alzheimer Abeta peptides in ion transport across cell membranes.

Ingram VM.

Subcell Biochem. 2005;38:339-49. Review.PMID: 15709487 [PubMed - indexed for MEDLINE]Related articles

Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody.

Colby DW, Chu Y, Cassady JP, Duennwald M, Zazulak H, Webster JM, Messer A, Lindquist S, Ingram VM, Wittrup KD.

Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17616-21. Epub 2004 Dec 14. Erratum in: Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):955. PMID: 15598740 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule.

Blanchard BJ, Chen A, Rozeboom LM, Stafford KA, Weigele P, Ingram VM.

Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14326-32. Epub 2004 Sep 23.PMID: 15388848 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of a human light chain variable domain (V(L)) intracellular antibody specific for the amino terminus of huntingtin via yeast surface display.

Colby DW, Garg P, Holden T, Chao G, Webster JM, Messer A, Ingram VM, Wittrup KD.

J Mol Biol. 2004 Sep 17;342(3):901-12.PMID: 15342245 [PubMed - indexed for MEDLINE]Related articles

Sickle-cell anemia hemoglobin: the molecular biology of the first "molecular disease"--the crucial importance of serendipity.

Ingram VM.

Genetics. 2004 May;167(1):1-7. No abstract available. PMID: 15166132 [PubMed - indexed for MEDLINE]Related articlesFree article

Elimination of Amyloid beta Neurotoxicity.

Blanchard BJ, Hiniker AE, Lu CC, Margolin Y, Yu AS, Ingram VM.

J Alzheimers Dis. 2000 Jun;2(2):137-149.PMID: 12214104 [PubMed - as supplied by publisher]Related articles

Uncoupling of mitochondria activates protein phosphatases and inactivates MBP protein kinases.

Luo Y, Ingram VM.

J Alzheimers Dis. 2001 Dec;3(6):593-598.PMID: 12214026 [PubMed - as supplied by publisher]Related articles

Eliminating membrane depolarization caused by the Alzheimer peptide Abeta(1-42, aggr.).

Blanchard BJ, Stockwell BR, Ingram VM.

Biochem Biophys Res Commun. 2002 May 17;293(4):1204-8.PMID: 12054503 [PubMed - indexed for MEDLINE]Related articles

Mechanism of membrane depolarization caused by the Alzheimer Abeta1-42 peptide.

Blanchard BJ, Thomas VL, Ingram VM.

Biochem Biophys Res Commun. 2002 May 17;293(4):1197-203.PMID: 12054502 [PubMed - indexed for MEDLINE]Related articles

Mechanism and prevention of neurotoxicity caused by beta-amyloid peptides: relation to Alzheimer's disease.

Blanchard BJ, Konopka G, Russell M, Ingram VM.

Brain Res. 1997 Nov 21;776(1-2):40-50.PMID: 9439794 [PubMed - indexed for MEDLINE]Related articles

Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP kinases.

Luo Y, Bond JD, Ingram VM.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9705-10.PMID: 9275188 [PubMed - indexed for MEDLINE]Related articlesFree article

Aggregates of a beta-amyloid peptide are required to induce calcium currents in neuron-like human teratocarcinoma cells: relation to Alzheimer's disease.

Sanderson KL, Butler L, Ingram VM.

Brain Res. 1997 Jan 2;744(1):7-14.PMID: 9030407 [PubMed - indexed for MEDLINE]Related articles

Hyperphosphorylation of the cytoskeletal protein Tau by the MAP-kinase PK40erk2: regulation by prior phosphorylation with cAMP-dependent protein kinase A.

Raghunandan R, Ingram VM.

Biochem Biophys Res Commun. 1995 Oct 24;215(3):1056-66.PMID: 7488031 [PubMed - indexed for MEDLINE]Related articles

Gene assignment by polymerase chain reaction: localization of the human potassium channel IsK gene to the Down's syndrome region of chromosome 21q22.1-q22.2.

Malo MS, Srivastava K, Ingram VM.

Gene. 1995 Jul 4;159(2):273-5.PMID: 7622063 [PubMed - indexed for MEDLINE]Related articles

Alzheimer tangles and abnormal phosphorylation.

Ingram VM.

Science. 1995 Mar 31;267(5206):1889-90. No abstract available. PMID: 7741944 [PubMed - indexed for MEDLINE]Related articles

Activation of a neurofilament kinase, a tau kinase, and a tau phosphatase by decreased ATP levels in nerve growth factor-differentiated PC-12 cells.

Bush ML, Miyashiro JS, Ingram VM.

Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1861-5.PMID: 7892192 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperphosphorylation of human TAU by brain kinase PK40erk beyond phosphorylation by cAMP-dependent PKA: relation to Alzheimer's disease.

Blanchard BJ, devi Raghunandan R, Roder HM, Ingram VM.

Biochem Biophys Res Commun. 1994 Apr 15;200(1):187-94.PMID: 8166686 [PubMed - indexed for MEDLINE]Related articles

Targeted gene walking by low stringency polymerase chain reaction: assignment of a putative human brain sodium channel gene (SCN3A) to chromosome 2q24-31.

Malo MS, Srivastava K, Andresen JM, Chen XN, Korenberg JR, Ingram VM.

Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):2975-9.PMID: 8159690 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization of a putative human brain sodium channel gene (SCN1A) to chromosome band 2q24.

Malo MS, Blanchard BJ, Andresen JM, Srivastava K, Chen XN, Li X, Jabs EW, Korenberg JR, Ingram VM.

Cytogenet Cell Genet. 1994;67(3):178-86.PMID: 8062593 [PubMed - indexed for MEDLINE]Related articles

Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease.

Roder HM, Eden PA, Ingram VM.

Biochem Biophys Res Commun. 1993 Jun 15;193(2):639-47.PMID: 8512563 [PubMed - indexed for MEDLINE]Related articles

A mitochondrial DNA deletion in normally aging and in Alzheimer brain tissue.

Blanchard BJ, Park T, Fripp WJ, Lerman LS, Ingram VM.

Neuroreport. 1993 Jun;4(6):799-802.PMID: 8347829 [PubMed - indexed for MEDLINE]Related articles

Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios.

Roder HM, Ingram VM.

J Neurosci. 1991 Nov;11(11):3325-43.PMID: 1719159 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective distribution of a novel tubulin in the developing and mature rat brain.

Gossels JM, Ingram VM.

Brain Res Dev Brain Res. 1990 Apr 1;53(1):103-15.PMID: 2350876 [PubMed - indexed for MEDLINE]Related articles

A tubulin identified by a monoclonal antibody is not present in mitotic spindles.

Gossels JM, Ingram VM.

Exp Cell Res. 1989 Oct;184(2):471-83.PMID: 2806400 [PubMed - indexed for MEDLINE]Related articles

Identification of a novel casein kinase activity in HeLa cell nuclei.

Friedrich TD, Ingram VM.

Biochim Biophys Acta. 1989 Jul 21;992(1):41-8.PMID: 2752037 [PubMed - indexed for MEDLINE]Related articles

Age-related neurofilament phosphorylation in normal human brains.

Blanchard BJ, Ingram VM.

Neurobiol Aging. 1989 May-Jun;10(3):253-8.PMID: 2747830 [PubMed - indexed for MEDLINE]Related articles

Abnormal human haemoglobins. I. The comparison of normal human and sickle-cell haemoglobins by "fingerprinting". 1958.

Ingram VM.

Biochim Biophys Acta. 1989;1000:151-7. No abstract available. PMID: 2673360 [PubMed - indexed for MEDLINE]Related articles

A case of sickle-cell anaemia: a commentary on 'Abnormal Human Haemoglobins. I. The Comparison of Normal Human and Sickle-Cell Haemoglobins by 'Fingerprinting" with II. The Chymotryptic Digestion of the Trypsin-resistant 'Core' of Haemoglobins A and S and III. The Chemical Difference Between Normal and Sickle Cell Haemoglobins.

Ingram VM.

Biochim Biophys Acta. 1989;1000:147-50. No abstract available. PMID: 2673358 [PubMed - indexed for MEDLINE]Related articles

Diversity among Purkinje cells in the monkey cerebellum.

Ingram VM, Ogren MP, Chatot CL, Gossels JM, Owens BB.

Proc Natl Acad Sci U S A. 1985 Oct;82(20):7131-5.PMID: 3901012 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth-dependent expression of multiple species of DNA methyltransferase in murine erythroleukemia cells.

Bestor TH, Ingram VM.

Proc Natl Acad Sci U S A. 1985 May;82(9):2674-8.PMID: 3857609 [PubMed - indexed for MEDLINE]Related articlesFree article

The DNA-methylating system of murine erythroleukemia cells.

Bestor T, Ingram VM.

Prog Clin Biol Res. 1985;198:95-104. No abstract available. PMID: 3865232 [PubMed - indexed for MEDLINE]Related articles

Differentiation of two mouse cell lines is associated with hypomethylation of their genomes.

Bestor TH, Hellewell SB, Ingram VM.

Mol Cell Biol. 1984 Sep;4(9):1800-6.PMID: 6092940 [PubMed - indexed for MEDLINE]Related articlesFree article

Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA.

Bestor TH, Ingram VM.

Proc Natl Acad Sci U S A. 1983 Sep;80(18):5559-63.PMID: 6577443 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and partial DNA sequence of the chicken beta H-globin gene.

Roninson IB, Ingram VM.

J Biol Chem. 1983 Jan 25;258(2):802-9.PMID: 6296082 [PubMed - indexed for MEDLINE]Related articlesFree article

DNA methylation of remote sequences in chicken alpha-globin gene expression.

Haigh LS, Owens BB, Ingram VM.

Prog Clin Biol Res. 1983;134:205-10.PMID: 6664998 [PubMed - indexed for MEDLINE]Related articles

Globin expression in Rous sarcoma virus-transformed quail myoblasts.

Farrell RL, Ingram VM.

Prog Clin Biol Res. 1983;134:263-6.PMID: 6320215 [PubMed - indexed for MEDLINE]Related articles

DNA methylation in chicken alpha-globin gene expression.

Haigh LS, Owens BB, Hellewell OS, Ingram VM.

Proc Natl Acad Sci U S A. 1982 Sep;79(17):5332-6.PMID: 6291038 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene evolution in the chicken beta-globin cluster.

Roninson IB, Ingram VM.

Cell. 1982 Mar;28(3):515-21.PMID: 6896168 [PubMed - indexed for MEDLINE]Related articles

Control of hemoglobin expression in chick embryonic development.

Haigh LS, Hellewell S, Roninson IB, Owens BB, Ingram VM.

Prog Clin Biol Res. 1982;102 pt A:35-46.PMID: 6897746 [PubMed - indexed for MEDLINE]Related articles

cDNA sequence of a new chicken embryonic rho-globin.

Roninson IB, Ingram VM.

Proc Natl Acad Sci U S A. 1981 Aug;78(8):4782-5.PMID: 6170981 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of ovotransferrin as a heme-, colony- and burst-stimulating factor in chick erythroid cell cultures.

Coll J, Ingram VM.

Exp Cell Res. 1981 Jan;131(1):173-84. No abstract available. PMID: 6969595 [PubMed - indexed for MEDLINE]Related articles

In vitro transcription of chromatin containing histones hyperacetylated in vivo.

Dobson ME, Ingram VM.

Nucleic Acids Res. 1980 Sep 25;8(18):4201-19.PMID: 7001364 [PubMed - indexed for MEDLINE]Related articlesFree article

Embryonic determination and differentiation.

Ingram VM, Keane RW.

Ann Intern Med. 1980 Apr;92(4):547-52.PMID: 7362158 [PubMed - indexed for MEDLINE]Related articles

Nucleosome-associated protein kinases in murine erythroleukemia cells.

Neumann JR, Owens BB, Ingram VM.

Arch Biochem Biophys. 1979 Oct 15;197(2):447-53. No abstract available. PMID: 292355 [PubMed - indexed for MEDLINE]Related articles

Isolation and transformation of primary mesenchymal cells of the chick embryo.

Keane RW, Lindblad PC, Pierik LT, Ingram VM.

Cell. 1979 Aug;17(4):801-11.PMID: 487430 [PubMed - indexed for MEDLINE]Related articles