PubMed

IDD3 and IDD5 alleles from nod mice mediate Sjögren's syndrome-like autoimmunity.

Cha S, Nagashima H, Peck AB, Humphreys-Beher MG.

Adv Exp Med Biol. 2002;506(Pt B):1035-9. No abstract available. PMID: 12614028 [PubMed - indexed for MEDLINE]Related articles

Immunogenetics of autoimmune exocrinopathy in the nod mouse: more than meets the eye.

Humphreys-Beher MG, Brayer J, Cha S, Nagashima H, Diggs S, Peck AB.

Adv Exp Med Biol. 2002;506(Pt B):999-1007. No abstract available. PMID: 12614023 [PubMed - indexed for MEDLINE]Related articles

Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjögren's syndrome) on a healthy murine background.

Cha S, Nagashima H, Brown VB, Peck AB, Humphreys-Beher MG.

Arthritis Rheum. 2002 May;46(5):1390-8.PMID: 12115247 [PubMed - indexed for MEDLINE]Related articlesFree article

Progress in understanding autoimmune exocrinopathy using the non-obese diabetic mouse: an update.

Cha S, Peck AB, Humphreys-Beher MG.

Crit Rev Oral Biol Med. 2002;13(1):5-16. Review.PMID: 12097234 [PubMed - indexed for MEDLINE]Related articlesFree article

Sjögren's syndrome: immunological response underlying the disease.

Brayer JB, Humphreys-Beher MG, Peck AB.

Arch Immunol Ther Exp (Warsz). 2001;49(5):353-60. Review.PMID: 11798133 [PubMed - indexed for MEDLINE]Related articles

The genetic control of sialadenitis versus arthritis in a NOD.QxB10.Q F2 cross.

Johansson AC, Nakken B, Sundler M, Lindqvist AK, Johannesson M, Alarcón-Riquelme M, Bolstad AI, Humphreys-Beher MG, Jonsson R, Skarstein K, Holmdahl R.

Eur J Immunol. 2002 Jan;32(1):243-50.PMID: 11782015 [PubMed - indexed for MEDLINE]Related articles

Polarized expression of G protein-coupled receptors and an all-or-none discharge of Ca2+ pools at initiation sites of [Ca2+]i waves in polarized exocrine cells.

Shin DM, Luo X, Wilkie TM, Miller LJ, Peck AB, Humphreys-Beher MG, Muallem S.

J Biol Chem. 2001 Nov 23;276(47):44146-56. Epub 2001 Sep 11.PMID: 11553617 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal organogenesis in salivary gland development may initiate adult onset of autoimmune exocrinopathy.

Cha S, van Blockland SC, Versnel MA, Homo-Delarche F, Nagashima H, Brayer J, Peck AB, Humphreys-Beher MG.

Exp Clin Immunogenet. 2001;18(3):143-60.PMID: 11549844 [PubMed - indexed for MEDLINE]Related articles

Reduced oral wound healing in the NOD mouse model for type 1 autoimmune diabetes and its reversal by epidermal growth factor supplementation.

Nagy A, Nagashima H, Cha S, Oxford GE, Zelles T, Peck AB, Humphreys-Beher MG.

Diabetes. 2001 Sep;50(9):2100-4.PMID: 11522677 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-4-dependent effector phase in autoimmune exocrinopathy as defined by the NOD.IL-4-gene knockout mouse model of Sjögren's syndrome.

Brayer JB, Cha S, Nagashima H, Yasunari U, Lindberg A, Diggs S, Martinez J, Goa J, Humphreys-Beher MG, Peck AB.

Scand J Immunol. 2001 Jul-Aug;54(1-2):133-40.PMID: 11439159 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor-alpha and receptors for it in labial salivary glands in Sjögren's syndrome.

Koski H, Janin A, Humphreys-Beher MG, Sorsa T, Malmström M, Konttinen YT.

Clin Exp Rheumatol. 2001 Mar-Apr;19(2):131-7.PMID: 11326474 [PubMed - indexed for MEDLINE]Related articles

Differential absorption and distribution of epidermal growth factor and insulin-like growth factor in diabetic NOD mice.

Clarke MY, Brayer J, Heintz K, Nagashima H, Cha S, Oxford GE, Nanni JM, Peck AB, Zelles T, Humphreys-Beher MG.

J Diabetes Complications. 2001 Mar-Apr;15(2):103-11.PMID: 11274907 [PubMed - indexed for MEDLINE]Related articles

Elevated proapoptotic Bax and caspase 3 activation in the NOD.scid model of Sjögren's syndrome.

Masago R, Aiba-Masago S, Talal N, Zuluaga FJ, Al-Hashimi I, Moody M, Lau CA, Peck AB, Brayer J, Humphreys-Beher MG, Dang H.

Arthritis Rheum. 2001 Mar;44(3):693-702.PMID: 11263785 [PubMed - indexed for MEDLINE]Related articlesFree article

Desipramine induced changes in salivary proteins, cultivable oral microbiota and gingival health in aging female NIA Fischer 344 rats.

Koller MM, Purushotham KR, Maeda N, Scarpace PJ, Humphreys-Beher MG.

Life Sci. 2000 Dec 15;68(4):445-55.PMID: 11205893 [PubMed - indexed for MEDLINE]Related articles

An analysis of parotid salivary gland function with desipramine and age in female NIA Fischer 344 rats.

Koller MM, Cowman RA, Humphreys-Beher MG, Scarpace PJ.

Exp Gerontol. 2001 Jan;36(1):141-57.PMID: 11162918 [PubMed - indexed for MEDLINE]Related articles

An analysis of submandibular salivary gland function with desipramine and age in female NIA Fischer 344 rats.

Koller MM, Cowman RA, Humphreys-Beher MG, Scarpace PJ.

Mech Ageing Dev. 2000 Nov 15;119(3):131-47.PMID: 11080533 [PubMed - indexed for MEDLINE]Related articles

Desipramine changes salivary gland function, oral microbiota, and oral health in rats.

Koller MM, Maeda N, Scarpace PJ, Humphreys-Beher MG.

Eur J Pharmacol. 2000 Nov 10;408(1):91-8.PMID: 11070187 [PubMed - indexed for MEDLINE]Related articles

Evidence for antimuscarinic acetylcholine receptor antibody-mediated secretory dysfunction in nod mice.

Nguyen KH, Brayer J, Cha S, Diggs S, Yasunari U, Hilal G, Peck AB, Humphreys-Beher MG.

Arthritis Rheum. 2000 Oct;43(10):2297-306.PMID: 11037890 [PubMed - indexed for MEDLINE]Related articlesFree article

Salivary EGF levels reduced in diabetic patients.

Oxford GE, Tayari L, Barfoot MD, Peck AB, Tanaka Y, Humphreys-Beher MG.

J Diabetes Complications. 2000 May-Jun;14(3):140-5.PMID: 10989322 [PubMed - indexed for MEDLINE]Related articles

Alleles from chromosomes 1 and 3 of NOD mice combine to influence Sjögren's syndrome-like autoimmune exocrinopathy.

Brayer J, Lowry J, Cha S, Robinson CP, Yamachika S, Peck AB, Humphreys-Beher MG.

J Rheumatol. 2000 Aug;27(8):1896-904.PMID: 10955330 [PubMed - indexed for MEDLINE]Related articles

Salivary epidermal growth factor levels decrease in patients receiving radiation therapy to the head and neck.

Dumbrigue HB, Sandow PL, Nguyen KH, Humphreys-Beher MG.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Jun;89(6):710-6.PMID: 10846125 [PubMed - indexed for MEDLINE]Related articles

Aberrant proteolytic digestion of biglycan and decorin by saliva and exocrine gland lysates from the NOD mouse model for autoimmune exocrinopathy.

Yamachika S, Brayer J, Oxford GE, Peck AB, Humphreys-Beher MG.

Clin Exp Rheumatol. 2000 Mar-Apr;18(2):233-40.PMID: 10812497 [PubMed - indexed for MEDLINE]Related articles

Transforming and epidermal growth factors in degenerated intervertebral discs.

Konttinen YT, Kemppinen P, Li TF, Waris E, Pihlajamäki H, Sorsa T, Takagi M, Santavirta S, Schultz GS, Humphreys-Beher MG.

J Bone Joint Surg Br. 1999 Nov;81(6):1058-63.PMID: 10615986 [PubMed - indexed for MEDLINE]Related articlesFree article

New concepts for the development of autoimmune exocrinopathy derived from studies with the NOD mouse model.

Humphreys-Beher MG, Peck AB.

Arch Oral Biol. 1999 May;44 Suppl 1:S21-5. Review.PMID: 10414851 [PubMed - indexed for MEDLINE]Related articles

The role of apoptosis in the initiation of the autoimmune response in Sjögren's syndrome.

Humphreys-Beher MG, Peck AB, Dang H, Talal N.

Clin Exp Immunol. 1999 Jun;116(3):383-7. Review. No abstract available. PMID: 10361223 [PubMed - indexed for MEDLINE]Related articlesFree article

An alternative perspective to the immune response in autoimmune exocrinopathy: induction of functional quiescence rather than destructive autoaggression.

Humphreys-Beher MG, Brayer J, Yamachika S, Peck AB, Jonsson R.

Scand J Immunol. 1999 Jan;49(1):7-10. Review.PMID: 10023850 [PubMed - indexed for MEDLINE]Related articles

Elevated levels of human salivary epidermal growth factor after oral and juxtaoral surgery.

Oxford GE, Jonsson R, Olofsson J, Zelles T, Humphreys-Beher MG.

J Oral Maxillofac Surg. 1999 Feb;57(2):154-8; discussion 158-9.PMID: 9973123 [PubMed - indexed for MEDLINE]Related articles

Excessive synthesis of matrix metalloproteinases in exocrine tissues of NOD mouse models for Sjögren's syndrome.

Yamachika S, Nanni JM, Nguyen KH, Garces L, Lowry JM, Robinson CP, Brayer J, Oxford GE, da Silveira A, Kerr M, Peck AB, Humphreys-Beher MG.

J Rheumatol. 1998 Dec;25(12):2371-80.PMID: 9858432 [PubMed - indexed for MEDLINE]Related articles

Inappropriate apoptosis of salivary and lacrimal gland epithelium of immunodeficient NOD-scid mice.

Kong L, Robinson CP, Peck AB, Vela-Roch N, Sakata KM, Dang H, Talal N, Humphreys-Beher MG.

Clin Exp Rheumatol. 1998 Nov-Dec;16(6):675-81.PMID: 9844759 [PubMed - indexed for MEDLINE]Related articles

Salivary gland changes in the NOD mouse model for Sjögren's syndrome: is there a non-immune genetic trigger?

Humphreys-Beher MG, Yamachika S, Yamamoto H, Maeda N, Nakagawa Y, Peck AB, Robinson CP.

Eur J Morphol. 1998 Aug;36 Suppl:247-51.PMID: 9825931 [PubMed - indexed for MEDLINE]Related articles

Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells.

Broverman RL, Nguyen KH, da Silveira A, Brinkley LL, Macauley SP, Zeng T, Yamamoto H, Tarnuzzer RW, Schultz GS, Kerr M, Humphreys-Beher MG.

J Dent Res. 1998 Jul;77(7):1504-14.PMID: 9663435 [PubMed - indexed for MEDLINE]Related articlesFree article

Transfer of human serum IgG to nonobese diabetic Igmu null mice reveals a role for autoantibodies in the loss of secretory function of exocrine tissues in Sjögren's syndrome.

Robinson CP, Brayer J, Yamachika S, Esch TR, Peck AB, Stewart CA, Peen E, Jonsson R, Humphreys-Beher MG.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7538-43.PMID: 9636185 [PubMed - indexed for MEDLINE]Related articlesFree article

Aberrant expression and potential function for parotid secretory protein (PSP) in the NOD (non-obese diabetic) mouse.

Robinson CP, Bounous DI, Alford CE, Peck AB, Humphreys-Beher MG.

Adv Exp Med Biol. 1998;438:925-30. No abstract available. PMID: 9634989 [PubMed - indexed for MEDLINE]Related articles

Infiltrating lymphocyte populations and cytokine production in the salivary and lacrimal glands of autoimmune NOD mice.

Robinson CP, Cornelius J, Bounous DI, Yamamoto H, Humphreys-Beher MG, Peck AB.

Adv Exp Med Biol. 1998;438:493-7. No abstract available. PMID: 9634926 [PubMed - indexed for MEDLINE]Related articles

Elevated salivary EGF levels stimulated by periodontal surgery.

Oxford GE, Nguyen KH, Alford CE, Tanaka Y, Humphreys-Beher MG.

J Periodontol. 1998 Apr;69(4):479-84.PMID: 9609379 [PubMed - indexed for MEDLINE]Related articles

Characterization of the changing lymphocyte populations and cytokine expression in the exocrine tissues of autoimmune NOD mice.

Robinson CP, Cornelius J, Bounous DE, Yamamoto H, Humphreys-Beher MG, Peck AB.

Autoimmunity. 1998;27(1):29-44.PMID: 9482205 [PubMed - indexed for MEDLINE]Related articles

A novel NOD-derived murine model of primary Sjögren's syndrome.

Robinson CP, Yamachika S, Bounous DI, Brayer J, Jonsson R, Holmdahl R, Peck AB, Humphreys-Beher MG.

Arthritis Rheum. 1998 Jan;41(1):150-6.PMID: 9433880 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of bromhexine as a treatment regimen in Sjögren's syndrome-like disease in the NOD (non-obese diabetic) mouse.

Nanni JM, Nguyen KH, Alford CE, Robinson CP, Stewart CM, Maeda N, Humphreys-Beher MG.

Clin Exp Rheumatol. 1997 Sep-Oct;15(5):515-21.PMID: 9307859 [PubMed - indexed for MEDLINE]Related articles

Extracellular-matrix gene expression during mouse submandibular gland development.

Macauley SP, Tarnuzzer RW, Schultz GS, Chegini N, Oxford GE, Humphreys-Beher MG.

Arch Oral Biol. 1997 Jun;42(6):443-54.PMID: 9382709 [PubMed - indexed for MEDLINE]Related articles

Elevated levels of cysteine protease activity in saliva and salivary glands of the nonobese diabetic (NOD) mouse model for Sjögren syndrome.

Robinson CP, Yamachika S, Alford CE, Cooper C, Pichardo EL, Shah N, Peck AB, Humphreys-Beher MG.

Proc Natl Acad Sci U S A. 1997 May 27;94(11):5767-71.PMID: 9159148 [PubMed - indexed for MEDLINE]Related articlesFree article

PSP expression in murine lacrimal glands and function as a bacteria binding protein in exocrine secretions.

Robinson CP, Bounous DI, Alford CE, Nguyen KH, Nanni JM, Peck AB, Humphreys-Beher MG.

Am J Physiol. 1997 Apr;272(4 Pt 1):G863-71.PMID: 9142919 [PubMed - indexed for MEDLINE]Related articles

Gastrointestinal absorption of insulin-like growth factor in the mouse in the absence of salivary insulin-like growth factor binding protein.

Nakagawa Y, Oxford GE, Ishibashi K, Yamamoto H, Maeda N, Bowen E, Brayer J, Humphreys-Beher MG.

Biochem Pharmacol. 1997 Jan 24;53(2):233-40.PMID: 9037256 [PubMed - indexed for MEDLINE]Related articles

Effects of chronic isoproterenol treatment or submandibular and sublingual ablation on microflora of mouse tooth surfaces.

Maeda N, Okamoto M, Nakagawa Y, Fujita H, Humphreys-Beher MG.

Microbiol Immunol. 1997;41(7):513-7.PMID: 9272696 [PubMed - indexed for MEDLINE]Related articles

Detection of alterations in the levels of neuropeptides and salivary gland responses in the non-obese diabetic mouse model for autoimmune sialoadenitis.

Yamamoto H, Ishibashi K, Nakagawa Y, Maeda N, Zeng T, Robinson CP, Oxford GE, Chegini N, Humphreys-Beher MG.

Scand J Immunol. 1997 Jan;45(1):55-61.PMID: 9010501 [PubMed - indexed for MEDLINE]Related articles

Inhibition of rat parotid gland growth response induced by chronic isoproterenol following treatment with quinolone antibiotics.

Kelentey B, Kerr M, Tao Z, Purushotham KR, Humphreys-Beher MG, Zelles T.

Mol Cell Biochem. 1996 Dec 6;165(1):55-63.PMID: 8974081 [PubMed - indexed for MEDLINE]Related articles

Cell cycle control in isoproterenol-induced murine salivary acinar cell proliferation.

Zeng T, Yamamoto H, Bowen E, Broverman RL, Nguyen KH, Humphreys-Beher MG.

Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996 Nov;115(3):271-9.PMID: 9375366 [PubMed - indexed for MEDLINE]Related articles

Animal models for autoimmune disease-associated xerostomia and xerophthalmia.

Humphreys-Beher MG.

Adv Dent Res. 1996 Apr;10(1):73-5. Review.PMID: 8934930 [PubMed - indexed for MEDLINE]Related articlesFree article

Competitive RNA templates for detection and quantitation of growth factors, cytokines, extracellular matrix components and matrix metalloproteinases by RT-PCR.

Tarnuzzer RW, Macauley SP, Farmerie WG, Caballero S, Ghassemifar MR, Anderson JT, Robinson CP, Grant MB, Humphreys-Beher MG, Franzen L, Peck AB, Schultz GS.

Biotechniques. 1996 Apr;20(4):670-4.PMID: 8800688 [PubMed - indexed for MEDLINE]Related articles

Genetically programmed development of salivary gland abnormalities in the NOD (nonobese diabetic)-scid mouse in the absence of detectable lymphocytic infiltration: a potential trigger for sialoadenitis of NOD mice.

Robinson CP, Yamamoto H, Peck AB, Humphreys-Beher MG.

Clin Immunol Immunopathol. 1996 Apr;79(1):50-9.PMID: 8612351 [PubMed - indexed for MEDLINE]Related articles

Alterations in the level of phosphotyrosine signal transduction constituents in human parotid tumors.

Bu R, Purushotham KR, Kerr M, Tao Z, Jonsson R, Olofsson J, Humphreys-Beher MG.

Proc Soc Exp Biol Med. 1996 Mar;211(3):257-64.PMID: 8633106 [PubMed - indexed for MEDLINE]Related articles